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List of works by Charla R. Secreto

Aberrant regulation of pVHL levels by microRNA promotes the HIF/VEGF axis in CLL B cells

scientific article published on 31 March 2009

Akt inhibitor MK-2206 in combination with bendamustine and rituximab in relapsed or refractory chronic lymphocytic leukemia: Results from the N1087 alliance study.

scientific article

Akt inhibitor MK2206 selectively targets CLL B-cell receptor induced cytokines, mobilizes lymphocytes and synergizes with bendamustine to induce CLL apoptosis

scientific article

Bi-directional activation between mesenchymal stem cells and CLL B-cells: implication for CLL disease progression

scientific article published on 08 September 2009

Bone marrow hematopoietic dysfunction in untreated chronic lymphocytic leukemia patients

scientific article published on 05 October 2018

Chronic lymphocytic leukemia cells from ibrutinib treated patients are sensitive to Axl receptor tyrosine kinase inhibitor therapy

Circulating microvesicles in B-cell chronic lymphocytic leukemia can stimulate marrow stromal cells: implications for disease progression

scientific article

Correction: potential therapeutic application of gold nanoparticles in B-chronic lymphocytic leukemia (BCLL): enhancing apoptosis.

scientific article published in July 2013

Curcumin inhibits prosurvival pathways in chronic lymphocytic leukemia B cells and may overcome their stromal protection in combination with EGCG.

scientific article published on February 2009

Deep sequencing identifies genetic heterogeneity and recurrent convergent evolution in chronic lymphocytic leukemia

scientific article

Direct and complement dependent cytotoxicity in CLL cells from patients with high-risk early-intermediate stage chronic lymphocytic leukemia (CLL) treated with alemtuzumab and rituximab

scientific article published on 27 June 2008

Early treatment of high-risk chronic lymphocytic leukemia with alemtuzumab and rituximab

scientific article

Genomic characterization of high-count MBL cases indicates that early detection of driver mutations and subclonal expansion are predictors of adverse clinical outcome

scientific article

Identification of recurrent truncated DDX3X mutations in chronic lymphocytic leukaemia.

scientific article published on 10 November 2014

Mcl-1 expression predicts progression-free survival in chronic lymphocytic leukemia patients treated with pentostatin, cyclophosphamide, and rituximab

scientific article

Monoclonal B-cell lymphocytosis is characterized by mutations in CLL putative driver genes and clonal heterogeneity many years before disease progression

scientific article

Pembrolizumab in patients with CLL and Richter transformation or with relapsed CLL.

scientific article published on 19 April 2017

Phase I trial of daily oral Polyphenon E in patients with asymptomatic Rai stage 0 to II chronic lymphocytic leukemia

scientific article published on 26 May 2009

Potential therapeutic application of gold nanoparticles in B-chronic lymphocytic leukemia (BCLL): enhancing apoptosis

scientific article published on 8 May 2007

Pretreatment angiogenic cytokines predict response to chemoimmunotherapy in patients with chronic lymphocytic leukaemia

scientific article published on 10 July 2009

Targeted Axl Inhibition Primes Chronic Lymphocytic Leukemia B Cells to Apoptosis and Shows Synergistic/Additive Effects in Combination with BTK Inhibitors

scientific article published on 11 February 2015

The novel receptor tyrosine kinase Axl is constitutively active in B-cell chronic lymphocytic leukemia and acts as a docking site of nonreceptor kinases: implications for therapy ⬇️

scientific article published on December 6, 2010

Tris (dibenzylideneacetone) dipalladium: a small-molecule palladium complex is effective in inducing apoptosis in chronic lymphocytic leukemia B-cells

scientific article published on 17 May 2016

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