Advanced search

Authors whose works are in public domain in at least one jurisdiction

List of works by Karl Barry Sharpless

1-50 of 125 results

View this query on the Wikidata Query Service
A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes

scientific article (publication date: 15 July 2002)
Click Chemistry: Diverse Chemical Function from a Few Good Reactions

scientific article (publication date: June 2001)
The growing impact of click chemistry on drug discovery

scientific article
Bioconjugation by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition

scientific article published in March 2003
Polytriazoles as copper(I)-stabilizing ligands in catalysis

scientific article
Catalytic Asymmetric Dihydroxylation

Copper(I)-catalyzed synthesis of azoles. DFT study predicts unprecedented reactivity and intermediates

scientific article
Efficiency and Fidelity in a Click-Chemistry Route to Triazole Dendrimers by the Copper(I)-Catalyzed Ligation of Azides and Alkynes

scholarly article by Peng Wu et al published 26 July 2004 in Angewandte Chemie International Edition
"On water": unique reactivity of organic compounds in aqueous suspension

scientific article
The first practical method for asymmetric epoxidation

scientific article (publication date: August 1980)
Ruthenium-catalyzed cycloaddition of alkynes and organic azides

scientific article
Click-Chemie: diverse chemische Funktionalität mit einer Handvoll guter Reaktionen

scientific article from 2001
Catalytic asymmetric epoxidation and kinetic resolution: modified procedures including in situ derivatization

article
The osmium-catalyzed asymmetric dihydroxylation: a new ligand class and a process improvement

scholarly article by Karl Barry Sharpless et al published May 1992 in Journal of Organic Chemistry
In situ click chemistry: enzyme inhibitors made to their own specifications

scientific article published in October 2004
A sulfilimine bond identified in collagen IV

scientific article
Multivalent, bifunctional dendrimers prepared by click chemistry

scientific article published on 4 November 2005
A potent and highly selective inhibitor of human alpha-1,3-fucosyltransferase via click chemistry

scientific article published in August 2003
Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation

scientific article
In situ selection of lead compounds by click chemistry: target-guided optimization of acetylcholinesterase inhibitors

scientific article published in May 2005
Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry

scientific article published on August 11, 2014
Copper(I)-catalyzed cycloaddition of organic azides and 1-iodoalkynes

scientific article
In situ click chemistry: enzyme-generated inhibitors of carbonic anhydrase II.

scientific article published in December 2004
Iterative in situ click chemistry creates antibody-like protein-capture agents

scientific article published on January 2009
Ligand-Accelerated Catalysis

Catalytic Asymmetric Aminohydroxylation(AA) of Olefins

Kinetic resolution of racemic allylic alcohols by enantioselective epoxidation. A route to substances of absolute enantiomeric purity?

scientific article published in 1981
In situclick chemistry: a powerful means for lead discovery

scientific article published on November 1, 2006
The allylic azide rearrangement: achieving selectivity

scientific article published in October 2005
Bisaryloxime ethers as potent inhibitors of transthyretin amyloid fibril formation

scientific article
Searching for new reactivity (Nobel lecture).

scientific article published in June 2002
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate

scientific article
New Structural Scaffolds for Centrally Acting Oxime Reactivators of Phosphylated Cholinesterases

scientific article published on April 4, 2011
Refinement of Structural Leads for Centrally Acting Oxime Reactivators of Phosphylated Cholinesterases

scientific article published on February 16, 2012
Mechanisms of tetrazole formation by addition of azide to nitriles

scientific article published in October 2002
Mechanistic studies on the Cu-catalyzed three-component reactions of sulfonyl azides, 1-alkynes and amines, alcohols, or water: dichotomy via a common pathway

scientific article published on 17 June 2008
Rapid discovery and structure-activity profiling of novel inhibitors of human immunodeficiency virus type 1 protease enabled by the copper(I)-catalyzed synthesis of 1,2,3-triazoles and their further functionalization

scientific article published in December 2006
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue

scientific article published on 18 May 2016
Identification of a new endogenous metabolite and the characterization of its protein interactions through an immobilization approach

scientific article published on January 2009
Why is tetrazole formation by addition of azide to organic nitriles catalyzed by zinc(II) salts?

scientific article published in August 2003
SuFEx‐Based Synthesis of Polysulfates

scientific article published on August 5, 2014
Synthesis and electrochemistry of 2-ethenyl and 2-ethanyl derivatives of 5-nitroimidazole and antimicrobial activity against Giardia lamblia

scientific article published on July 2009
Toward an Understanding of the High Enantioselectivity in the Osmium-Catalyzed Asymmetric Dihydroxylation. 4. Electronic Effects in Amine-Accelerated Osmylations

scholarly article by Derek W. Nelson et al published February 1997 in Journal of the American Chemical Society
Bringing Efficiency to Materials Synthesis: The Philosophy of Click Chemistry

Generation of Candidate Ligands for Nicotinic Acetylcholine Receptors via in situ Click Chemistry with a Soluble Acetylcholine Binding Protein Template

scientific article
Inhibitors of VIM-2 by screening pharmacologically active and click-chemistry compound libraries

scientific article published on 22 June 2009
Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1

scientific article published on October 24, 2011
Mechanism of asymmetric epoxidation. 2. Catalyst structure

scientific article published in 1991
Electrophilic and nucleophilic organoselenium reagents. New routes to .alpha.,.beta.-unsaturated carbonyl compounds

scientific article published in 1973
Expanded therapeutic potential in activity space of next-generation 5-nitroimidazole antimicrobials with broad structural diversity

scientific article published on 07 October 2013

Paulina is supported by:

About Paulina

Help