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List of works by Manabu Okumura

Adsorption of irinotecan onto oral adsorbent AST-120 (Kremezin) for preventing delayed diarrhea

scientific article published on 13 June 2006

Analysis of CYP3A inhibitory components of star fruit (Averrhoa carambola L.) using liquid chromatography-mass spectrometry

scientific article published on 25 March 2008

Caffeine increases the antitumor effect of Cisplatin in human hepatocellular carcinoma cells.

scientific article

Effect of P-glycoprotein modulator, cyclosporin A, on the gastrointestinal excretion of irinotecan and its metabolite SN-38 in rats

scientific article

Effect of acute hepatic failure on epirubicin pharmacokinetics after intrahepatic arterial injection in rats

scientific article

Effect of acute hepatic failure on the hepatic first-pass effect of 5-fluorouracil in rats

scientific article published on May 2010

Effects of pomegranate juice on human cytochrome P450 2C9 and tolbutamide pharmacokinetics in rats

scientific article published on 28 November 2006

Effects of pomegranate juice on human cytochrome p450 3A (CYP3A) and carbamazepine pharmacokinetics in rats

scientific article

Hepatic fibrosis does not affect the pharmacokinetics of 5-fluorouracil in rats

scientific article published on 28 December 2010

Hepatocyte growth factor increases uptake of estradiol 17beta-D-glucuronide and Oatp1 protein level in rat hepatocytes

scientific article published on 25 October 2007

Hepatocyte growth factor suppresses the anticancer effect of irinotecan by decreasing the level of active metabolite in HepG2 cells.

scientific article published on 5 August 2011

Inhibition of carrier-mediated uptake of epirubicin reduces cytotoxicity in primary culture of rat hepatocytes.

scientific article published in April 2008

Inhibitory effects of amino-acid fluids on drug binding to site II of human serum albumin in vitro

scientific article published in March 2005

Inhibitory effects of citrus fruits on cytochrome P450 3A (CYP3A) activity in humans

scientific article published in September 2003

Inhibitory effects of fruit juices on cytochrome P450 2C9 activity in vitro.

scientific article published on 7 February 2008

Isolation of cytochrome P450 3A (CYP3A) inhibitors from Hyuganatsu, Citrus tamurana Hort

scientific article published on 14 April 2006

Potent inhibition by star fruit of human cytochrome P450 3A (CYP3A) activity

scientific article

Relationship between UGT1A1*27 and UGT1A1*7 polymorphisms and irinotecan-related toxicities in patients with lung cancer.

scientific article

Retrospective analysis of the correlation between tacrolimus concentrations measured in whole blood and variations of blood cell counts in patients undergoing allogeneic haematopoietic stem cell transplantation

scientific article published on 16 November 2018

Transient inhibition of cyp3a in rats by star fruit juice

scientific article published on 2 December 2005