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List of works by Diane F. Jelinek

A promising approach for treatment of tumor-induced bone diseases: utilizing bisphosphonate derivatives of nucleoside antimetabolites

scientific article

A rare case of selective Igκ chain deficiency: Biologic and clinical implications

scientific article published on 03 April 2020

A recombinant IL-4-Pseudomonas exotoxin inhibits protein synthesis and overcomes apoptosis resistance in human CLL B cells

scientific article published on 12 April 2005

A role for BLyS in the activation of innate immune cells

scientific article published on 6 July 2006

A role for Janus kinases in crosstalk between ErbB3 and the interferon-alpha signaling complex in myeloma cells

scientific article published on February 2004

A role for insulin-like growth factor in the regulation of IL-6-responsive human myeloma cell line growth

scientific article published on July 1997

A role for phosphatidylinositol 3-kinase in generating T cell help for B cell growth and differentiation

scientific article published on 01 October 1996

A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union

scientific article

A-Miz-ing BCL6.

scientific article published in October 2005

AML-1A and AML-1B regulation of MIP-1alpha expression in multiple myeloma.

scientific article

Aberrant expression of B-lymphocyte stimulator by B chronic lymphocytic leukemia cells: a mechanism for survival

scientific article published on 01 October 2002

Acquired chromosomal anomalies in chronic lymphocytic leukemia patients compared with more than 50,000 quasi-normal participants

scientific article

Age at diagnosis and the utility of prognostic testing in patients with chronic lymphocytic leukemia

scientific article published on October 2010

Akt inhibitor MK-2206 in combination with bendamustine and rituximab in relapsed or refractory chronic lymphocytic leukemia: Results from the N1087 alliance study.

scientific article

Alternative splicing regulates activation-induced cytidine deaminase (AID): implications for suppression of AID mutagenic activity in normal and malignant B cells

scientific article published on 06 August 2008

Analysis of IL-6-mediated growth control of myeloma cells using a gp130 chimeric receptor approach

scientific article

Analysis of clonal B-cell CD38 and immunoglobulin variable region sequence status in relation to clinical outcome for B-chronic lymphocytic leukaemia

scientific article published on 01 December 2001

Angiogenesis in B-chronic lymphocytic leukemia

scientific article published on 01 June 2001

Angiogenesis in B-chronic lymphocytic leukemia

scientific article published on 01 August 2001

Atypical expression of ErbB3 in myeloma cells: cross-talk between ErbB3 and the interferon-alpha signaling complex

scientific article published on June 2003

Autoimmune cytopenia in chronic lymphocytic leukemia/small lymphocytic lymphoma: changes in clinical presentation and prognosis

scientific article

B lymphocyte stimulator regulates adaptive immune responses by directly promoting dendritic cell maturation

scientific article published on June 2008

B-CLL cells are capable of synthesis and secretion of both pro- and anti-angiogenic molecules

scientific article published on 01 May 2002

B-CLL: is the enigma of disease heterogeneity about to be revealed?

scientific article published in August 2002

B-cell count and survival: differentiating chronic lymphocytic leukemia from monoclonal B-cell lymphocytosis based on clinical outcome

scientific article

BCL2 mutations are associated with increased risk of transformation and shortened survival in follicular lymphoma

scientific article

Biologic and genetic characterization of the novel amyloidogenic lambda light chain-secreting human cell lines, ALMC-1 and ALMC-2.

scientific article

Biological evaluation of CpG stimulation of normal human B‐cells: implications for B‐cell biology and cytogenetic analysis of CLL B‐cells ⬇️

scientific article published on February 17, 2011

Bone marrow stromal cells protect lymphoma B‐cells from rituximab‐induced apoptosis and targeting integrin α‐4‐β‐1 (VLA‐4) with natalizumab can overcome this resistance ⬇️

scientific article (publication date: October 2011)

Brief report: natural history of individuals with clinically recognized monoclonal B-cell lymphocytosis compared with patients with Rai 0 chronic lymphocytic leukemia

scientific article published on 20 July 2009

CD147 regulates the expression of MCT1 and lactate export in multiple myeloma cells

scientific article published on 03 September 2013

CD38 expression levels in chronic lymphocytic leukemia B cells are associated with activation marker expression and differential responses to interferon stimulation

scientific article published in December 2005

CD40 expression in malignant plasma cells. Role in stimulation of autocrine IL-6 secretion by a human myeloma cell line.

scientific article published on January 1994

CD49d associates with nodal presentation and subsequent development of lymphadenopathy in patients with chronic lymphocytic leukaemia

scientific article published on 7 April 2017

CD49d expression is an independent predictor of overall survival in patients with chronic lymphocytic leukaemia: a prognostic parameter with therapeutic potential

scientific article published on March 2008

CLL B cells with a bimodal CD38 expression pattern: persistence of bimodal populations despite effective therapy for B-CLL ⬇️

scientific article published on 01 January 2004

Cd4+ T-cell immune response to large B-cell non-Hodgkin's lymphoma predicts patient outcome

scientific article published in February 2001

Characterization and use of the novel human multiple myeloma cell line MC-B11/14 to study biological consequences of CRISPR-mediated loss of immunoglobulin A heavy chain

scientific article published on 10 October 2017

Chromosome anomalies detected by interphase fluorescence in situ hybridization: correlation with significant biological features of B-cell chronic lymphocytic leukaemia

scientific article published on 01 April 2003

Chronic Lymphocytic Leukemia with Mutated IGHV4-34 Receptors: Shared and Distinct Immunogenetic Features and Clinical Outcomes

scientific article published on 23 May 2017

Chronic lymphocytic leukemia

scientific article published on 01 January 2002

Chronic lymphocytic leukemia in young (≤ 55 years) patients: a comprehensive analysis of prognostic factors and outcomes

scientific article

Clinical Course and Prognosis of Smoldering (Asymptomatic) Multiple Myeloma

article

Clinical effect of stereotyped B-cell receptor immunoglobulins in chronic lymphocytic leukaemia: a retrospective multicentre study

scientific article

Clonotypic Light Chain Peptides Identified for Monitoring Minimal Residual Disease in Multiple Myeloma without Bone Marrow Aspiration

scientific article published on October 2015

Coexistence of aneuploid subclones within a myeloma cell line that exhibits clonal immunoglobulin gene rearrangement: clinical implications

scientific article published on November 1993

Combination chemoimmunotherapy with pentostatin, cyclophosphamide, and rituximab shows significant clinical activity with low accompanying toxicity in previously untreated B chronic lymphocytic leukemia

scientific article

Comparative activation requirements of human peripheral blood, spleen, and lymph node B cells

scientific article published on 01 August 1987

Comparison of Multiple Myeloma Donor Patient Samples and Derived Cell Lines Identifies a Confirmed Hyperdiploid Myeloma Cell Line and Demonstrates Remarkable Genetic Similarity Between Cell Lines and Patient Samples

scientific article published on 18 April 2020

Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: results from the US Intergroup Phase III Trial E2997.

scientific article published on 5 February 2007

Comprehensive assessment of potential multiple myeloma immunoglobulin heavy chain V-D-J intraclonal variation using massively parallel pyrosequencing

scientific article

Cytogenetic abnormalities can change during the course of the disease process in chronic lymphocytic leukemia

scientific article published on 01 July 2006

Cytogenetic prioritization with inclusion of molecular markers predicts outcome in previously untreated patients with chronic lymphocytic leukemia treated with fludarabine or fludarabine plus cyclophosphamide: a long-term follow-up study of the US i

scientific article

Delineation of the functional capacity of human neonatal lymphocytes ⬇️

scientific article published on February 1, 1991

Development of a cell with dendritic morphology from a precursor of B lymphocyte lineage

scientific article published on 01 April 1987

Differential human multiple myeloma cell line responsiveness to interferon-alpha. Analysis of transcription factor activation and interleukin 6 receptor expression

scientific article published on February 1997

Differentiation of Chronic Lymphocytic Leukemia B Cells into Immunoglobulin Secreting Cells Decreases LEF-1 Expression ⬇️

scientific article published on October 6, 2011

Direct and complement dependent cytotoxicity in CLL cells from patients with high-risk early-intermediate stage chronic lymphocytic leukemia (CLL) treated with alemtuzumab and rituximab

scientific article published on 27 June 2008

Dissociation between IFN-alpha-induced anti-viral and growth signaling pathways

scientific article published on March 1999

Divergent effects of BAFF on human memory B cell differentiation into Ig-secreting cells

scientific article published in May 2007

Early treatment of high-risk chronic lymphocytic leukemia with alemtuzumab and rituximab

scientific article

Effects of Interferon Alpha on Myeloma Cells: Mechanisms of Differential Responsiveness ⬇️

scientific article published on 01 January 1997

Elevated serum B-lymphocyte stimulator levels in patients with familial lymphoproliferative disorders

scientific article

Enhancement of human B cell proliferation and differentiation by tumor necrosis factor-alpha and interleukin 1

scientific article published on 01 November 1987

Eosinophil purification from human bone marrow

scientific article published on 01 January 2014

Eosinophils regulate peripheral B cell numbers in both mice and humans

scientific article published on 10 March 2014

Establishment and characterization of three myeloma cell lines that demonstrate variable cytokine responses and abilities to produce autocrine interleukin-6.

scientific article published on May 1996

Evidence for ongoing DNA damage in multiple myeloma cells as revealed by constitutive phosphorylation of H2AX

scientific article published on 13 May 2011

Evolutionary dynamics of two related malignant plasma cell lines ⬇️

scientific article published on September 15, 2010

Expression and function of Fas (APO-1/CD95) in patient myeloma cells and myeloma cell lines.

scientific article

Expression of BCMA, TACI, and BAFF-R in multiple myeloma: a mechanism for growth and survival ⬇️

scientific article (publication date: 15 January 2004)

Expression of BLyS and its receptors in B-cell non-Hodgkin lymphoma: correlation with disease activity and patient outcome

scientific article

Expression of TCL-1 as a potential prognostic factor for treatment outcome in B-cell chronic lymphocytic leukemia

scientific article

Fluorescent-labeled DNA probes applied to novel biological aspects of B-cell chronic lymphocytic leukemia

scientific article published on 01 March 2005

Gene-expression profiling of Waldenstrom macroglobulinemia reveals a phenotype more similar to chronic lymphocytic leukemia than multiple myeloma

scientific article

Genetic characterization of SF3B1 mutations in single chronic lymphocytic leukemia cells ⬇️

scientific article published on May 20, 2013

Genetic variation in 1253 immune and inflammation genes and risk of non-Hodgkin lymphoma

scientific article

Growth regulatory pathways in myeloma. Evidence for autocrine oncostatin M expression.

scientific article published on October 1996

Higher-order connections between stereotyped subsets: implications for improved patient classification in CLL

scientific article published on 29 September 2020

Human B lymphocyte malignancies: exploitation of BLyS and APRIL and their receptors

scientific article

Human peripheral blood B lymphocyte subpopulations: functional and phenotypic analysis of surface IgD positive and negative subsets

scientific article published on 01 January 1986

Hypogammaglobulinemia in newly diagnosed chronic lymphocytic leukemia: Natural history, clinical correlates, and outcomes

scientific article

IL-3 expression by myeloma cells increases both osteoclast formation and growth of myeloma cells

scientific article published on 13 November 2003

Ibrutinib-Rituximab or Chemoimmunotherapy for Chronic Lymphocytic Leukemia

scientific article published on 01 August 2019

Identification of a global gene expression signature of B-chronic lymphocytic leukemia.

scientific article published in March 2003

Immunogenetics shows that not all MBL are equal: the larger the clone, the more similar to CLL.

scientific article published on 17 April 2013

Immunoglobulin diversity gene usage predicts unfavorable outcome in a subset of chronic lymphocytic leukemia patients

scientific article

Immunoglobulin free light chain ratio is an independent risk factor for progression of smoldering (asymptomatic) multiple myeloma

scientific article

Immunoglobulin heavy variable (IGHV) genes and alleles: new entities, new names and implications for research and prognostication in chronic lymphocytic leukaemia

scientific article

Immunomodulatory role of IL-4 on the secretion of Ig by human B cells

scientific article published on 01 March 1989

In vitro autoantibody production by normal adult and cord blood B cells

scientific article

Increased expression of extracellular matrix metalloproteinase inducer (CD147) in multiple myeloma: role in regulation of myeloma cell proliferation ⬇️

scientific article published on March 30, 2012

Increased signaling through p62 in the marrow microenvironment increases myeloma cell growth and osteoclast formation

scientific article published on 12 March 2009

Induction of Malignant Plasma Cell Proliferation by Eosinophils ⬇️

scientific article published on July 22, 2013

Infection and killing of multiple myeloma by adenoviruses

scientific article

Infectious complications among individuals with clinical monoclonal B-cell lymphocytosis (MBL): a cohort study of newly diagnosed cases compared to controls

scientific article published on 11 July 2012

Inhibition of human B cell responsiveness by prostaglandin E2

scientific article published on 01 February 1987

Inhibition of survivin expression suppresses the growth of aggressive non-Hodgkin's lymphoma

scientific article published on 01 March 2004

Inhibitory influence of IL-4 on human B cell responsiveness

scientific article published on 01 July 1988

Interleukin 6 induces monocyte chemoattractant protein-1 expression in myeloma cells

scientific article published on October 2002

Karyotype evolution on fluorescent in situ hybridization analysis is associated with short survival in patients with chronic lymphocytic leukemia and is related to CD49d expression

scientific article published on May 2008

LEF-1 is a prosurvival factor in chronic lymphocytic leukemia and is expressed in the preleukemic state of monoclonal B-cell lymphocytosis

scientific article

Long-term repair of T-cell synapse activity in a phase II trial of chemoimmunotherapy followed by lenalidomide consolidation in previously untreated chronic lymphocytic leukemia (CLL).

scientific article published on 14 March 2013

Longitudinal genome-wide analysis of patients with chronic lymphocytic leukemia reveals complex evolution of clonal architecture at disease progression and at the time of relapse.

scientific article published on 20 January 2012

MBL or CLL: which classification best categorizes the clinical course of patients with an absolute lymphocyte count >or= 5 x 10(9) L(-1) but a B-cell lymphocyte count <5 x 10(9) L(-1)?

scientific article published on 07 January 2008

MIP-1alpha utilizes both CCR1 and CCR5 to induce osteoclast formation and increase adhesion of myeloma cells to marrow stromal cells.

scientific article published on March 2005

Mcl-1 expression predicts progression-free survival in chronic lymphocytic leukemia patients treated with pentostatin, cyclophosphamide, and rituximab

scientific article

Methylprednisolone-rituximab is an effective salvage therapy for patients with relapsed chronic lymphocytic leukemia including those with unfavorable cytogenetic features

scientific article published in December 2007

Molecular analysis of immunoglobulin genes reveals frequent clonal relatedness in double monoclonal gammopathies

scientific article published on 19 April 2013

Molecular and biological role of CD40 in multiple myeloma

scientific article published on 01 January 1995

Monitoring M-Proteins in Patients with Multiple Myeloma Using Heavy-Chain Variable Region Clonotypic Peptides and LC–MS/MS

scientific article published on 05 March 2014

Multiple myeloma dell-derived microvesicles are enriched in CD147 expression and enhance tumor cell proliferation

scientific article

Multiplex Immunofluorescence of Bone Marrow Core Biopsies: Visualizing the Bone Marrow Immune Contexture

scientific article published on 19 December 2019

Myeloma research goes 3D

scientific article published on 01 October 2008

No improvement in long-term survival over time for chronic lymphocytic leukemia patients in stereotyped subsets #1 and #2 treated with chemo(immuno)therapy

scientific article published on 21 December 2017

Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations

scientific article

Ofatumumab‐based chemoimmunotherapy is effective and well tolerated in patients with previously untreated chronic lymphocytic leukemia (CLL) ⬇️

scientific article published on 06 August 2013

Pentostatin and rituximab therapy for previously untreated patients with B-cell chronic lymphocytic leukemia

scientific article

Percentage of smudge cells on routine blood smear predicts survival in chronic lymphocytic leukemia

scientific article published on 02 March 2009

Phase 1 study of interleukin-12 in combination with rituximab in patients with B-cell non-Hodgkin lymphoma ⬇️

scientific article published on 01 January 2002

Phase 2 trial of daily, oral Polyphenon E in patients with asymptomatic, Rai stage 0 to II chronic lymphocytic leukemia

scientific article published on 03 July 2012

Phase I trial of daily oral Polyphenon E in patients with asymptomatic Rai stage 0 to II chronic lymphocytic leukemia

scientific article published on 26 May 2009

Phase II trials of single-agent anti-VEGF therapy for patients with chronic lymphocytic leukemia ⬇️

scientific article published on November 5, 2010

Phenotyping polyclonal kappa and lambda light chain molecular mass distributions in patient serum using mass spectrometry

scientific article published on 26 August 2014

Phosphatidylinositol 3-kinase activation in normal human B lymphocytes

scientific article published on 01 June 1996

Platelet-derived growth factor (PDGF)-PDGF receptor interaction activates bone marrow-derived mesenchymal stromal cells derived from chronic lymphocytic leukemia: implications for an angiogenic switch

scientific article

Prevalence and risk of progression of light-chain monoclonal gammopathy of undetermined significance: a retrospective population-based cohort study

scientific article

Prognostic importance of T and NK-cells in a consecutive series of newly diagnosed patients with chronic lymphocytic leukaemia

scientific article published on April 2008

Progressive but previously untreated CLL patients with greater array CGH complexity exhibit a less durable response to chemoimmunotherapy

scientific article

Prospective evaluation of clonal evolution during long-term follow-up of patients with untreated early-stage chronic lymphocytic leukemia

scientific article

Protein expression profiling of CLL B cells using replicate off-line strong cation exchange chromatography and LC-MS/MS

scientific article published on 01 May 2005

Proteomic detection of immunoglobulin light chain variable region peptides from amyloidosis patient biopsies

scientific article published on 20 March 2015

Purification of functional eosinophils from human bone marrow ⬇️

scientific article published on October 22, 2012

Quantitative DNA methylation analysis identifies a single CpG dinucleotide important for ZAP-70 expression and predictive of prognosis in chronic lymphocytic leukemia

scientific article

Quantitative protein expression analysis of CLL B cells from mutated and unmutated IgV(H) subgroups using acid-cleavable isotope-coded affinity tag reagents

scientific article

Regulated expression of BAFF-binding receptors during human B cell differentiation

scientific article published in December 2007

Regulation of human B cell activation by prostaglandin E2. Suppression of the generation of immunoglobulin-secreting cells

scientific article published on April 1985

Regulation of human B cell proliferation by prostaglandin E2

scientific article published on 01 November 1984

Regulation of human B lymphocyte activation, proliferation, and differentiation

scientific article published on January 1987

Regulation of human B lymphocyte responsiveness

scientific article published on January 1988

Responsiveness of cytogenetically discrete human myeloma cell lines to lenalidomide: lack of correlation with cereblon and interferon regulatory factor 4 expression levels

scientific article published on 17 September 2013

Risk factors for development of a second lymphoid malignancy in patients with chronic lymphocytic leukaemia

scientific article published in November 2007

Role of long non-coding RNAs in disease progression of early stage unmutated chronic lymphocytic leukemia

Selective induction of DNA repair pathways in human B cells activated by CD4+ T cells

scientific article

Selective inhibition of inflammatory gene expression in activated T lymphocytes: a mechanism of immune suppression by thiopurines

scientific article published on 23 September 2004

Sequence, expression and function of an mRNA encoding a soluble form of the human interleukin-6 receptor (sIL-6R).

scientific article published on January 1995

Sharpening spots: correcting for bleedover in cDNA array images

scientific article published in March 2002

Species D Adenoviruses as Oncolytics against B-cell Cancers ⬇️

scientific article published on September 2, 2011

Survival of patients with clinically identified monoclonal B-cell lymphocytosis (MBL) relative to the age- and sex-matched general population

scientific article published on 12 August 2011

T cell-dependent activation of B cell proliferation and differentiation by immobilized monoclonal antibodies to CD3

scientific article published on 01 June 1988

TALEN-mediated genetic tailoring as a tool to analyze the function of acquired mutations in multiple myeloma cells

scientific article

The Histone Methyltransferase MMSET Regulates Class Switch Recombination ⬇️

scientific article published on December 14, 2012

The oncogenic transcription factor IRF4 is regulated by a novel CD30/NF-κB positive feedback loop in peripheral T-cell lymphoma

scientific article published on April 2015

The prognostic significance of cytopenia in chronic lymphocytic leukaemia/small lymphocytic lymphoma

scientific article

The role of B cell proliferation in the generation of immunoglobulin-secreting cells in man ⬇️

scientific article published on 01 June 1983

The roles of T cell factors in activation, cell cycle progression, and differentiation of human B cells

scientific article published on 01 March 1985

The roles of interleukin 2 and interferon-gamma in human B cell activation, growth and differentiation

scientific article published on 01 August 1986

The structure of the TNFRSF13C promoter enables differential expression of BAFF-R during B cell ontogeny and terminal differentiation.

scientific article published on 16 June 2010

Transactivation of gp130 in myeloma cells

scientific article published in April 2003

Transcriptional and post-transcriptional mechanisms of BAFF-receptor dysregulation in human B lineage malignancies

scientific article

Uncovering the biology of multiple myeloma among African Americans: a comprehensive genomics approach

scientific article published on 19 February 2013

Using smudge cells on routine blood smears to predict clinical outcome in chronic lymphocytic leukemia: a universally available prognostic test

scientific article

VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia

scientific article published on 2 March 2004

VEGF receptors on chronic lymphocytic leukemia (CLL) B cells interact with STAT 1 and 3: implication for apoptosis resistance

scientific article published in April 2005

Validation of a new prognostic index for patients with chronic lymphocytic leukemia

scientific article published on January 2009

ZAP-70 is expressed by a subset of normal human B-lymphocytes displaying an activated phenotype

scientific article published in June 2005

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