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List of works by Dobromir Dobrev

2014 ESC/EACTS Guidelines on myocardial revascularization: the Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Developed with the special contri

scientific article

2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS

article by Paulus Kirchhof et al published 27 August 2016 in EP Europace

2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS.

scientific article

A roadmap to improve the quality of atrial fibrillation management: proceedings from the fifth Atrial Fibrillation Network/European Heart Rhythm Association consensus conference

scientific article

Ablation of the calpain-targeted site in cardiac myosin binding protein-C is cardioprotective during ischemia-reperfusion injury

scientific article published on 09 March 2019

Acute atrial tachyarrhythmia induces angiotensin II type 1 receptor-mediated oxidative stress and microvascular flow abnormalities in the ventricles.

scientific article published on 05 March 2009

Acute effects of alcohol on cardiac electrophysiology and arrhythmogenesis: Insights from multiscale in silico analyses

scientific article published on 22 July 2020

Aldosterone-receptor antagonism as a potential therapeutic option for atrial fibrillation

scientific article published on April 2010

Alterations in the interactome of serine/threonine protein phosphatase type-1 in atrial fibrillation patients.

scientific article

Altered atrial metabolism: an underappreciated contributor to the initiation and progression of atrial fibrillation

scientific article published on 15 March 2015

Altered calcium-handling produces reentry-promoting action potential alternans in atrial fibrillation-remodeled hearts

scientific article published on 07 April 2020

An aqueous extract of the marine sponge Ectyoplasia ferox stimulates L-type Ca2+-current by direct interaction with the Cav1.2 subunit

scientific article

Angiotensin Receptor-Neprilysin Inhibitor (ARNI) and Cardiac Arrhythmias ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2021

Animal models for atrial fibrillation: clinical insights and scientific opportunities.

scientific article published on 29 October 2009

Antiarrhythmic drugs for atrial fibrillation: Imminent impulses are emerging

Application of the RIMARC algorithm to a large data set of action potentials and clinical parameters for risk prediction of atrial fibrillation.

scientific article

Assessment of OMT-28, a synthetic analog of omega-3 epoxyeicosanoids, in patients with persistent atrial fibrillation: Rationale and design of the PROMISE-AF phase II study

scientific article published on 10 July 2020

Atrial Fibrillation Activates AMP-Dependent Protein Kinase and its Regulation of Cellular Calcium Handling: Potential Role in Metabolic Adaptation and Prevention of Progression.

scientific article

Atrial Myocyte NLRP3/CaMKII Nexus Forms a Substrate for Post-Operative Atrial Fibrillation

scientific article published on 30 July 2020

Atrial fibrillation in a dish: Insights into atrial arrhythmogenesis from induced pluripotent stem cell derived cardiomyocytes

scientific article published on 20 December 2019

Atrial fibrillation in sub-Saharan Africa: The knowns and unknowns?

article

Atrial fibrillation promotion by endurance exercise: demonstration and mechanistic exploration in an animal model.

scientific article published on 10 April 2013

Atrial remodeling and atrial fibrillation: mechanisms and implications.

scientific article published on April 2008

Atrial-selective sodium channel block by dronedarone: sufficient to terminate atrial fibrillation? ⬇️

scientific article published on 04 May 2011

Bayesian network analyses in atrial fibrillation - A path to better therapies?

Breaking bad: Higher risk of osteoporosis with vitamin K antagonists compared to direct oral anticoagulants in patients with atrial fibrillation

scientific article published on 10 April 2020

COVID-19 associated atrial fibrillation: Incidence, putative mechanisms and potential clinical implications

scientific article published on 01 September 2020

Ca(2+)-related signaling and protein phosphorylation abnormalities play central roles in a new experimental model of electrical storm

scientific article published on 09 May 2011

CaMKII activity contributes to homeometric autoregulation of the heart: a novel mechanism for the Anrep effect

scientific article published on 12 May 2020

Calcium Handling Abnormalities as a Target for Atrial Fibrillation Therapeutics: How Close to Clinical Implementation?

scientific article published on 27 March 2015

Calcium Signaling and Cardiac Arrhythmias

scientific article

Calcium dysregulation in atrial fibrillation: the role of CaMKII

scientific article

Calcium handling abnormalities in atrial fibrillation as a target for innovative therapeutics.

scientific article published on October 2008

Calcium handling and atrial fibrillation.

scientific article published on July 2012

Calcium-handling abnormalities underlying atrial arrhythmogenesis and contractile dysfunction in dogs with congestive heart failure

scientific article published on 30 April 2008

Calcium-mediated cellular triggered activity in atrial fibrillation

scientific article published on 9 February 2017

Calmodulin kinase II, sarcoplasmic reticulum Ca2+ leak, and atrial fibrillation

scientific article published on January 2010

Calmodulin kinase II-mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in mice

scientific article

Can cystatin C-based estimated glomerular filtration rate help to guide individualized risk factor modification programs?

scientific article

Cardiac CaM Kinase II genes δ and γ contribute to adverse remodeling but redundantly inhibit calcineurin-induced myocardial hypertrophy

scientific article

Cardiac safety assays

scientific article

Cardiac sympathetic innervation and control of potassium channel function

scientific article published on 01 February 2003

Cardiomyocyte Inflammasome Signaling in Cardiomyopathies and Atrial Fibrillation: Mechanisms and Potential Therapeutic Implications

scientific article published on 13 August 2018

Cardiomyocyte calcium handling in health and disease: Insights from in vitro and in silico studies

scientific article published on 15 March 2020

Cellular and molecular correlates of ectopic activity in patients with atrial fibrillation ⬇️

scientific article published on November 1, 2012

Cellular and molecular electrophysiology of atrial fibrillation initiation, maintenance, and progression

scientific article published on April 2014

Cellular and molecular mechanisms of atrial arrhythmogenesis in patients with paroxysmal atrial fibrillation.

scientific article

Cellular signaling underlying atrial tachycardia remodeling of L-type calcium current

scientific article published on 21 August 2008

Challenges to the translation of basic science findings to atrial fibrillation therapies

scientific article published on 19 April 2016

Changes in I K, ACh single-channel activity with atrial tachycardia remodelling in canine atrial cardiomyocytes

scientific article published on 26 October 2007

Chronic loss of inhibitor-1 diminishes cardiac RyR2 phosphorylation despite exaggerated CaMKII activity

scientific article

Comparing the global mRNA expression profile of human atrial and ventricular myocardium with high-density oligonucleotide arrays.

scientific article

Comprehensive risk reduction in patients with atrial fibrillation: emerging diagnostic and therapeutic options--a report from the 3rd Atrial Fibrillation Competence NETwork/European Heart Rhythm Association consensus conference

scientific article published on 26 July 2011

Computational modeling: What does it tell us about atrial fibrillation therapy?

scientific article published on 25 January 2019

Computational models of atrial cellular electrophysiology and calcium handling, and their role in atrial fibrillation.

scientific article

Constitutive activity of the acetylcholine-activated potassium current IK,ACh in cardiomyocytes.

scientific article

Constitutively active phosphatase inhibitor-1 improves cardiac contractility in young mice but is deleterious after catecholaminergic stress and with aging

scientific article

Contemporary plaque imaging for risk stratification of coronary artery disease: Are we getting there?

scientific article published on 24 November 2020

Controversies About Atrial Fibrillation Mechanisms: Aiming for Order in Chaos and Whether it Matters

scientific article

Coronary clot composition after myocardial infarction: Thrombus age matters

scientific article published on 12 December 2019

Counteracting Protein Kinase Activity in the Heart: The Multiple Roles of Protein Phosphatases

scientific article

DPP10 is a new regulator of Nav1.5 channels in human heart

scientific article published on 03 January 2019

Deciphering the fundamental mechanisms of atrial fibrillation: a quest for over a century

scientific article published on 7 February 2016

Decreased ATP-sensitive K(+) current density during chronic human atrial fibrillation

scientific article

Decreased phosphorylation levels of cardiac myosin-binding protein-C in human and experimental heart failure

scientific article

Defective cardiac ryanodine receptor regulation during atrial fibrillation

scientific article published in April 2005

Defects in ankyrin-based membrane protein targeting pathways underlie atrial fibrillation

scientific article

Detailed characterization of microRNA changes in a canine heart failure model: Relationship to arrhythmogenic structural remodeling

scientific article published on 12 October 2014

Differences in Left Versus Right Ventricular Electrophysiological Properties in Cardiac Dysfunction and Arrhythmogenesis

scientific article published on May 2016

Differential phosphorylation-dependent regulation of constitutively active and muscarinic receptor-activated IK,ACh channels in patients with chronic atrial fibrillation

scientific article

Differential protein kinase C isoform regulation and increased constitutive activity of acetylcholine-regulated potassium channels in atrial remodeling.

scientific article published on 8 September 2011

Distinct contractile and molecular differences between two goat models of atrial dysfunction: AV block-induced atrial dilatation and atrial fibrillation

scientific article

Do genetics help to better understand the underlying mechanisms of atrial fibrillation?

scientific article published on 07 June 2006

Double Jeopardy: Will the new trials tell us how to manage patients with atrial fibrillation and coronary artery disease?

Dynamic balance of platelet reactivity in atrial fibrillation PARtially unravelled

scientific article published on 01 September 2017

EHRA White Paper: knowledge gaps in arrhythmia management-status 2019

article by Andreas Goette et al published 1 July 2019 in EP Europace

EHRA/HRS/APHRS/SOLAECE expert consensus on Atrial cardiomyopathies: Definition, characterisation, and clinical implication.

scientific article

EHRA/HRS/APHRS/SOLAECE expert consensus on atrial cardiomyopathies: Definition, characterization, and clinical implication.

scientific article published on 10 June 2016

EHRA/HRS/APHRS/SOLAECE expert consensus on atrial cardiomyopathies: definition, characterization, and clinical implication.

scientific article

Effects of immunoglobulin G from patients with dilated cardiomyopathy on rat cardiomyocytes

scientific article published in June 2005

Electrical storm: recent pathophysiological insights and therapeutic consequences.

scientific article published on 21 February 2013

Electrocardiographic characteristics associated with atrial fibrillation - What do they tell us?

scientific article published on 01 September 2018

Electrophysiological and molecular mechanisms of paroxysmal atrial fibrillation

scientific article published on 4 August 2016

Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial Fibrillation

Enhanced myofilament responsiveness upon β-adrenergic stimulation in post-infarct remodeled myocardium

scientific article published on 13 December 2010

Enhanced sarcoplasmic reticulum Ca2+ leak and increased Na+-Ca2+ exchanger function underlie delayed afterdepolarizations in patients with chronic atrial fibrillation

scientific article

Erratum: "Revealing kinetics and state-dependent binding properties of IKur-targeting drugs that maximize atrial fibrillation selectivity" [Chaos 27, 093918 (2017)].

scientific article published in October 2017

Expression and function of Kv1.1 potassium channels in human atria from patients with atrial fibrillation.

scientific article

Facilitated electrical cardioversion: does the selection of the antiarrhythmic drug matter?

scientific article published on 01 September 2019

Fibroblast inward-rectifier potassium current upregulation in profibrillatory atrial remodeling.

scientific article published on 21 January 2015

Four and a half LIM protein 1: a novel chaperone for atrium-specific Kv1.5 channels with a potential role in atrial arrhythmogenesis

scientific article published on 05 April 2008

Function and regulation of serine/threonine phosphatases in the healthy and diseased heart.

scientific article

Genome-wide association studies of atrial fibrillation: Finding meaning in the life of risk loci

scientific article published on 08 July 2019

Guía ESC 2015 sobre el tratamiento de pacientes con arritmiasventriculares y prevención de la muerte súbita cardiaca

Guía ESC 2016 sobre el diagnóstico y tratamiento de la fibrilación auricular, desarrollada en colaboración con la EACTS

Heart failure with preserved ejection fraction meets atrial fibrillation: Is enhanced inflammasome signaling a major common mechanism leading to these 2 frequent diseases?

scientific article published on 07 March 2020

Highlights from the International Journal of Cardiology Heart & Vasculature: Heart failure, atrial fibrillation, coronary artery disease and myocardial infarction

scientific article published on 20 November 2019

Human atrial action potential and Ca2+ model: sinus rhythm and chronic atrial fibrillation

scientific article published on 15 September 2011

Human atrial ion channel and transporter subunit gene-expression remodeling associated with valvular heart disease and atrial fibrillation.

scientific article

Human inward rectifier potassium channels in chronic and postoperative atrial fibrillation

scientific article

Identification of microRNA-mRNA dysregulations in paroxysmal atrial fibrillation.

scientific article published on 28 January 2015

Identification of optimal reference genes for transcriptomic analyses in normal and diseased human heart

scientific article published on 22 September 2017

Impaired Na⁺-dependent regulation of acetylcholine-activated inward-rectifier K⁺ current modulates action potential rate dependence in patients with chronic atrial fibrillation.

scientific article published on 24 March 2013

Impaired local regulation of ryanodine receptor type 2 by protein phosphatase 1 promotes atrial fibrillation.

scientific article

In Silico Assessment of Efficacy and Safety of IKur Inhibitors in Chronic Atrial Fibrillation: Role of Kinetics and State-Dependence of Drug Binding. ⬇️

scientific article published on 7 November 2017

Inhibition of CaMKII phosphorylation of RyR2 prevents induction of atrial fibrillation in FKBP12.6 knockout mice

scientific article published on 8 December 2011

Inhibition of IK,ACh current may contribute to clinical efficacy of class I and class III antiarrhythmic drugs in patients with atrial fibrillation

scientific article published on 17 September 2009

Inhibition of Small-Conductance Ca2+-Activated K+ Channels: The Long-Awaited Breakthrough for Antiarrhythmic Drug Therapy of Atrial Fibrillation?

scientific article published in October 2017

Innovative Therapeutics for Atrial Fibrillation: Imminent Breakthroughs or Much Ado About Nothing?

scientific article published on 01 November 2015

Inositol Trisphosphate Receptors and Nuclear Calcium in Atrial Fibrillation

scientific article published on 30 December 2020

Integrating new approaches to atrial fibrillation management: the 6th AFNET/EHRA Consensus Conference

scientific article published on 2 January 2018

Intracellular calcium leak due to FKBP12.6 deficiency in mice facilitates the inducibility of atrial fibrillation.

scientific article published on 27 March 2008

Inverse remodelling of K2P3.1 K+ channel expression and action potential duration in left ventricular dysfunction and atrial fibrillation: implications for patient-specific antiarrhythmic drug therapy

scientific article published on 4 January 2017

Investigational antiarrhythmic agents: promising drugs in early clinical development.

scientific article

Ion channels as part of macromolecular multiprotein complexes : Clinical significance

scientific article published on 6 December 2017

Irregular rhythm and atrial metabolism are key for the evolution of proarrhythmic atrial remodeling in atrial fibrillation

scientific article published on 28 May 2015

Isolation of Human Atrial Myocytes for Simultaneous Measurements of Ca<sup>2+</sup> Transients and Membrane Currents ⬇️

scientific article published on 03 July 2013

JAK-STAT signaling and the atrial fibrillation promoting fibrotic substrate.

scientific article

KCNQ1 autoantibodies: another way to regulate IKs.

scientific article

Left-to-right atrial inward rectifier potassium current gradients in patients with paroxysmal versus chronic atrial fibrillation

scientific article published on 24 July 2010

Left-ventricular innervation assessed by 123I-SPECT/CT is associated with cardiac events in inherited arrhythmia syndromes

scientific article published on 06 March 2020

Loss of Protein Phosphatase 1 Regulatory Subunit PPP1R3A Promotes Atrial Fibrillation

scientific article published on 12 June 2019

Loss of SPEG Inhibitory Phosphorylation of RyR2 Promotes Atrial Fibrillation

scientific article published on 20 July 2020

Loss of cardiomyocyte integrin-linked kinase produces an arrhythmogenic cardiomyopathy in mice

scientific article published on 12 June 2015

Loss of microRNA-106b-25 cluster promotes atrial fibrillation by enhancing ryanodine receptor type-2 expression and calcium release.

scientific article

Maastricht antiarrhythmic drug evaluator (MANTA): A computational tool for better understanding of antiarrhythmic drugs

scientific article published on 04 September 2019

Management of patients with newly-diagnosed atrial fibrillation: Insights from the BALKAN-AF survey

scientific article published on 28 December 2019

Mechanisms of atrial tachyarrhythmias associated with coronary artery occlusion in a chronic canine model

scientific article published on 03 January 2011

Methods for isolating atrial cells from large mammals and humans

scientific article

MicroRNA regulation and cardiac calcium signaling: role in cardiac disease and therapeutic potential

scientific article

MicroRNA29: a mechanistic contributor and potential biomarker in atrial fibrillation

scientific article published on 4 March 2013

Molecular Basis of Atrial Fibrillation Pathophysiology and Therapy: A Translational Perspective

scientific article published on 18 June 2020

Molecular determinants of altered Ca2+ handling in human chronic atrial fibrillation

scientific article published on 07 August 2006

Mouse Models of Cardiac Arrhythmias

scientific article published on 01 July 2018

Multiple potential molecular contributors to atrial hypocontractility caused by atrial tachycardia remodeling in dogs.

scientific article

Muscarinic subtype-2 receptor autoantibodies: actors or bystanders in human atrial fibrillation?

scientific article published in July 2004

Muscarinic type-1 receptors contribute to IK,ACh in human atrial cardiomyocytes and are upregulated in patients with chronic atrial fibrillation

scientific article published on 22 December 2017

Mutation E169K in junctophilin-2 causes atrial fibrillation due to impaired RyR2 stabilization.

scientific article published on 21 August 2013

NSC23766, a widely used inhibitor of Rac1 activation, additionally acts as a competitive antagonist at muscarinic acetylcholine receptors

scientific article published on 25 July 2013

New antiarrhythmic drugs for treatment of atrial fibrillation.

scientific article published on 22 March 2010

New antiarrhythmic targets in atrial fibrillation

scientific article

New directions in antiarrhythmic drug therapy for atrial fibrillation

scientific article published on January 2013

New insights into the molecular basis of atrial fibrillation: mechanistic and therapeutic implications

scientific article published on 04 February 2011

Nightly sleep apnea severity in patients with atrial fibrillation: Potential applications of long-term sleep apnea monitoring

scientific article published on 01 September 2019

No evidence for an association between the rs2824292 variant at chromosome 21q21 and ventricular fibrillation during acute myocardial infarction in a German population

scientific article published on 17 May 2011

Non-ion channel therapeutics for heart failure and atrial fibrillation: Are CaMKII inhibitors ready for clinical use?

scientific article published on 24 October 2017

Novel anti-arrhythmic agents for the treatment of atrial fibrillation

scientific article published on 15 February 2007

Novel molecular targets for atrial fibrillation therapy

scientific article published on 30 March 2012

Nucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure.

scientific article published on 07 December 2016

Nucleoside diphosphate kinase B-activated intermediate conductance potassium channels are critical for neointima formation in mouse carotid arteries.

scientific article

On-demand mobile health infrastructures to allow comprehensive remote atrial fibrillation and risk factor management through teleconsultation

scientific article published on 08 October 2020

One for all and all for one? The dilemma of optimal management of atrial fibrillation with cardiac co-morbidities

scientific article published on 07 October 2019

Outcome of atrial fibrillation ablation in pulmonary hypertension: Is pulmonary hypertension a modifiable risk factor?

Oxidized Ca(2+)/calmodulin-dependent protein kinase II triggers atrial fibrillation.

scientific article

Oxidized CaMKII causes cardiac sinus node dysfunction in mice.

scientific article published on 25 July 2011

PITX2: a master regulator of cardiac channelopathy in atrial fibrillation?

scientific article published on 17 January 2016

Palmitoylation and membrane association of the stress axis regulated insert (STREX) controls BK channel regulation by protein kinase C

scientific article published on 29 July 2012

Personalized management of atrial fibrillation: Proceedings from the fourth Atrial Fibrillation competence NETwork/European Heart Rhythm Association consensus conference

scientific article

Pharmacological evidence for altered src kinase regulation of I (Ca,L) in patients with chronic atrial fibrillation

scientific article

Phosphatase inhibitor-1-deficient mice are protected from catecholamine-induced arrhythmias and myocardial hypertrophy

scientific article published on 8 August 2008

Phosphatase-1 inhibitor-1 in physiological and pathological -adrenoceptor signalling ⬇️

scientific article published on February 24, 2011

Phosphodiesterase-2 is up-regulated in human failing hearts and blunts β-adrenergic responses in cardiomyocytes

scientific article published on 26 June 2013

Pleiotropic actions of amiodarone: still puzzling after half a century

scientific article published on 9 April 2013

Pleiotropic actions of ticagrelor versus clopidogrel - Do molecular differences translate into superior clinical efficacy after myocardial infarction?

scientific article published on 03 April 2020

Pleiotropic effects of antiarrhythmic agents: dronedarone in the treatment of atrial fibrillation

scientific article published on 11 August 2013

Polypill revisited - Unity in diversity

scientific article published on 10 August 2020

Postoperative atrial fibrillation: mechanisms, manifestations and management

scientific article published on 01 July 2019

Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics

scientific article published on 3 November 2016

Pro-arrhythmic RyR2 channels in heart failure: do their localisation and mechanism of activation really matter?

scientific article published on 01 September 2018

Proarrhythmic atrial calcium cycling in the diseased heart.

scientific article published on January 2012

Problem-based learning: a new pathway to competence?

scientific article published in April 2002

Profibrotic, Electrical, and Calcium-Handling Remodeling of the Atria in Heart Failure Patients With and Without Atrial Fibrillation

article by Cristina E Molina et al published 2018 in Frontiers in Physiology

Prognostic impact of electrical storm in patients with implantable cardioverter defibrillators: Mechanistic and therapeutic considerations to reduce the risk of death.

scientific article published in March 2018

Rat engineered heart tissue: a novel tool in the safety pharmacology toolkit?

scientific article published on 11 September 2014

Rate-adaptive pacing using intracardiac impedance shows no evidence for positive feedback during dobutamine stress test

scientific article

Recent advances in the molecular pathophysiology of atrial fibrillation.

scientific article

Recording atrial monophasic action potentials using standard pacemaker leads: an alternative way to study electrophysiology properties of the human atrium in vivo?

scientific article published in December 2004

Recurrence of atrial fibrillation following non-cardiac surgery or acute illness: A common but rarely detected complication

scientific article published on 06 August 2020

Regulating the regulator: Insights into the cardiac protein phosphatase 1 interactome

scientific article published on 20 September 2016

Regulation of heterotrimeric G-protein signaling by NDPK/NME proteins and caveolins: an update

scientific article published on 16 October 2017

Remodeling of cardiomyocyte ion channels in human atrial fibrillation

scientific article

Remodelling of cardiac repolarization: how homeostatic responses can lead to arrhythmogenesis.

scientific article published on 30 September 2008

Repurposing traditional immunomodulators to target the inflammatory burden of atherosclerosis

scientific article published on 12 May 2020

Response to Letter Regarding Article, "Upregulation of K2P3.1 K+ Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation"

scientific article published on 01 March 2016

Response to: "The emerging role of hybrid ablation for ablation" by Spartialis M. et al.

scientific article published in December 2017

Resveratrol: an effective pharmacological agent to prevent inflammation-induced atrial fibrillation?

scientific article published on 20 September 2018

Revealing kinetics and state-dependent binding properties of IKur-targeting drugs that maximize atrial fibrillation selectivity.

scientific article published on September 2017

Rhythm control of atrial fibrillation in heart failure.

scientific article

Role of IKur in controlling action potential shape and contractility in the human atrium: influence of chronic atrial fibrillation

scientific article published on 11 October 2004

Role of RyR2 phosphorylation at S2814 during heart failure progression

scientific article

Role of RyR2 phosphorylation in heart failure and arrhythmias: Controversies around ryanodine receptor phosphorylation in cardiac disease

scientific article

Role of T-type calcium channel subunits in post-myocardial infarction remodelling probed with genetically engineered mice

scientific article published on 27 May 2011

Role of autonomic nervous system in atrial fibrillation

scientific article published on 18 November 2018

Role of calcineurin and protein phosphatase-2A in the regulation of phosphatase inhibitor-1 in cardiac myocytes

scientific article

Role of small-conductance calcium-activated potassium channels in atrial electrophysiology and fibrillation in the dog.

scientific article published on 4 November 2013

Role of triggers and substrate in heart failure based atrial fibrillation: Is pulmonary vein isolation still the cornerstone of atrial fibrillation therapy?

scientific article published on 01 September 2017

Ryanodine receptor-mediated calcium leak drives progressive development of an atrial fibrillation substrate in a transgenic mouse model

scientific article

S-glutathiolation impairs phosphoregulation and function of cardiac myosin-binding protein C in human heart failure.

scientific article published on 2 February 2016

SPEG: a key regulator of cardiac calcium homeostasis

scientific article published on 17 October 2020

Safety and efficacy of vernakalant for acute cardioversion of atrial fibrillation: an update ⬇️

scientific article published on April 23, 2013

Serine/Threonine Phosphatases in Atrial Fibrillation

scientific article published on 7 January 2017

Sleep apnea and atrial fibrillation: Update 2020

scientific article published on 27 November 2020

Smart device-based detection of atrial fibrillation: Opportunities and challenges in the emerging world of digital health

scientific article published on 14 December 2019

Straight to the heart: Pleiotropic antiarrhythmic actions of oral anticoagulants

scientific article published on 02 May 2019

Stroke prevention versus bleeding risk of vitamin-K antagonists: a double-edged sword in patients with atrial fibrillation who require surgery

scientific article published in January 2009

Switching off the jitters: Dabigatran as a candidate approach to halt atrial fibrillation?

scientific article published on 13 June 2018

Systems approaches to post-operative atrial fibrillation - do they help us to better understand the ionic basis of the arrhythmogenic substrate?

scientific article published on 21 June 2012

T-type calcium current contributes to escape automaticity and governs the occurrence of lethal arrhythmias after atrioventricular block in mice

scientific article published on 24 July 2013

Tachycardia-induced silencing of subcellular Ca2+ signaling in atrial myocytes

scientific article

Targeting atrial fibrillation promoting atrial structural remodeling: is this a viable strategy in patients with heart failure?

scientific article

Targeting supraventricular ectopic complexes: Which approach should be used and how does it affect atrial fibrillation?

scientific article published on 01 October 2017

The European Network for Translational Research in Atrial Fibrillation (EUTRAF): objectives and initial results

scientific article published on 12 September 2015

The German Competence Network on Atrial Fibrillation (AFNET).

scientific article published in December 2008

The anticoagulation dilemma and future treatment avenues in patients with breast cancer and atrial fibrillation

scientific article published on 01 October 2020

The biology of human pulmonary veins: does it help us to better understand AF pathophysiology in patients?

scientific article published on 11 December 2012

The clinical profile and pathophysiology of atrial fibrillation: relationships among clinical features, epidemiology, and mechanisms

scientific article

The combined effects of ranolazine and dronedarone on human atrial and ventricular electrophysiology

scientific article published on 4 April 2016

The gut microbial-derived metabolite trimethylamine N-oxide: A missing link between lifestyle-components and atrial fibrillation?

scientific article published on 23 July 2020

The impact of rapid atrial pacing on ADMA and endothelial NOS

scientific article published on 05 October 2010

The inward rectifier current inhibitor PA-6 terminates atrial fibrillation and does not cause ventricular arrhythmias in goat and dog models.

scientific article

The multidimensional role of calcium in atrial fibrillation pathophysiology: mechanistic insights and therapeutic opportunities

scientific article published on 16 April 2012

The multiple proarrhythmic roles of cardiac calcium-handling abnormalities: triggered activity, conduction abnormalities, beat-to-beat variability, and adverse remodelling

scientific article published on 29 January 2016

The not-so-sweet problem of hearts aflutter: Dissecting stroke risk in atrial fibrillation with concomitant diabetes

scientific article published on 19 May 2018

The role of amiodarone in contemporary management of complex cardiac arrhythmias

scientific article published on 19 November 2019

The ryanodine receptor channel as a molecular motif in atrial fibrillation: pathophysiological and therapeutic implications

scientific article published on 12 October 2010

The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation: a critical analysis

scientific article published on 23 December 2015

Thrombin receptor PAR4 drives canonical NLRP3 inflammasome signaling in the heart

scientific article published on 07 January 2020

Tools to Keep the Clock Ticking: Molecular Approaches to Treat Sinus Node Dysfunction

scientific article published on 04 June 2015

Transient receptor potential canonical-3 channel-dependent fibroblast regulation in atrial fibrillation

scientific article published on 19 September 2012

Translational Challenges in Atrial Fibrillation

scientific article

Upregulation of K(2P)3.1 K+ Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation

scientific article published on 7 May 2015

Use of pulsed electron avalanche knife (PEAK) PlasmaBlade™ in patients undergoing implantation of subcutaneous implantable cardioverter-defibrillator

scientific article published on 05 July 2019

Voltage-clamp-based methods for the detection of constitutively active acetylcholine-gated I(K,ACh) channels in the diseased heart

scientific article published on January 2010

Voltage‐gated Na+ channels: novel players in fibroblast‐to‐myofibroblast transition with a potential role in atrial arrhythmogenesis? ⬇️

scientific article published on October 15, 2012

What is a good tutorial from the student's point of view? Evaluation of tutorials in a newly established PBL block course "Basics of Drug Therapy".

scientific article published on 22 May 2002

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