List of works by Hervé Perron

A cytotoxic factor for glial cells: a new avenue of research for multiple sclerosis?

scientific article published on September 1997

A gliotoxic factor and multiple sclerosis

scientific article published on February 1998

A new therapeutic approach for type 1 diabetes: rationale for GNbAC1 an anti-HERV-W-Env monoclonal antibody.

scientific article published on 10 May 2018

A phase IIa randomised clinical study of GNbAC1, a humanised monoclonal antibody against the envelope protein of multiple sclerosis-associated endogenous retrovirus in multiple sclerosis patients

scientific article

A phase IIa randomized clinical study testing GNbAC1, a humanized monoclonal antibody against the envelope protein of multiple sclerosis associated endogenous retrovirus in multiple sclerosis patients - a twelve month follow-up

scientific article published on 20 May 2015

A urinary marker for multiple sclerosis

scientific article published on 01 May 1998

An ancestral retroviral protein identified as a therapeutic target in type-1 diabetes

scientific article published on 7 September 2017

Antibody to reverse transcriptase of human retroviruses in multiple sclerosis

scientific article published on December 1991

Case report: DNA fragmentation in glial cells in a cerebral biopsy from a multiple sclerosis patient

scientific article published in June 1998

Cell cultures and associated retroviruses in multiple sclerosis. Collaborative Research Group on MS.

scientific article published on January 1997

Correlation between disease severity and in vitro cytokine production mediated by MSRV (Multiple Sclerosis associated RetroViral element) envelope protein in patients with multiple sclerosis

scientific article published on 08 December 2004

Correlation between milk and dairy product consumption and multiple sclerosis prevalence: a worldwide study

scientific article

Coxsackievirus-B4 Infection Can Induce the Expression of Human Endogenous Retrovirus W in Primary Cells

scientific article published on 01 September 2020

Detection of a gliotoxic activity in the cerebrospinal fluid from multiple sclerosis patients

scientific article published on 01 March 1998

Detection of virion-associated MSRV-RNA in serum of patients with multiple sclerosis

scientific article published on 01 January 1998

Development of a pan-retrovirus detection system for multiple sclerosis studies.

scientific article published in January 1997

Endogenous retroviral genes, Herpesviruses and gender in Multiple Sclerosis

scientific article

Endogenous retroviral sequences in the human genome can play a physiological or pathological role

scientific article published on April 2017

Endogenous retrovirus type W GAG and ENV antigenaemia in serum of schizophrenic patients

scientific article published on 24 September 2009

Endogenous retrovirus type W GAG and envelope protein antigenemia in serum of schizophrenic patients

scientific article published on 29 August 2008

Erratum: Molecular characteristics of Human Endogenous Retrovirus type-W in schizophrenia and bipolar disorder

scholarly article published in Translational Psychiatry

Exposure to infant siblings during early life and risk of multiple sclerosis

scientific article published on 01 May 2005

Expression of endogenous retroviruses in blood mononuclear cells and brain tissue from multiple sclerosis patients

scientific article published in June 1995

Expression of endogenous retroviruses in blood mononuclear cells and brain tissue from multiple sclerosis patients

scientific article published on 01 January 1997

First international workshop on human endogenous retroviruses and diseases, HERVs & disease 2015

scientific article

GNbAC1, a humanized monoclonal antibody against the envelope protein of multiple sclerosis-associated endogenous retrovirus: a first-in-humans randomized clinical study

scientific article

Glial toxicity in urine and multiple sclerosis

scientific article published on December 2001

Gliotoxic factor and multiple sclerosis

scientific article published in April 1996

Gliotoxicity, reverse transcriptase activity and retroviral RNA in monocyte/macrophage culture supernatants from patients with multiple sclerosis

scientific article published on August 1997

HERV-W envelope is significantly expressed in Multiple Sclerosis and causes neuroinflammation in animal models with specific antibody inhibition

Herpes simplex virus ICP0 and ICP4 immediate early proteins strongly enhance expression of a retrovirus harboured by a leptomeningeal cell line from a patient with multiple sclerosis

scientific article published on January 1993

Human Endogenous Retrovirus and Neuroinflammation in Chronic Inflammatory Demyelinating Polyradiculoneuropathy.

scientific article published on 10 March 2016

Human Endogenous Retroviruses and Type 1 Diabetes

scientific article published on 21 November 2019

Human Endogenous Retroviruses in Neurological Diseases.

scientific article published on 15 March 2018

Human endogenous retroviral protein triggers deficit in glutamate synapse maturation and behaviors associated with psychosis

scientific article published on 17 July 2020

Human endogenous retrovirus (HERV)-W ENV and GAG proteins: physiological expression in human brain and pathophysiological modulation in multiple sclerosis lesions

scientific article published in February 2005

Human endogenous retrovirus W in brain lesions: Rationale for targeted therapy in multiple sclerosis

scientific article published on 22 April 2016

Human endogenous retrovirus protein activates innate immunity and promotes experimental allergic encephalomyelitis in mice

scientific article

Human endogenous retrovirus type W (HERV-W) in schizophrenia: a new avenue of research at the gene-environment interface

scientific article published on 22 September 2011

Human endogenous retrovirus type W envelope expression in blood and brain cells provides new insights into multiple sclerosis disease.

scientific article published on 28 March 2012

Human endogenous retrovirus type W envelope protein inhibits oligodendroglial precursor cell differentiation

scientific article published on 16 September 2013

Human viral superantigens: to be or not to be transactivated?

scientific article published on 01 May 2002

In vitro transmission and antigenicity of a retrovirus isolated from a multiple sclerosis patient

scientific article published in September 1992

Induction of Proinflammatory Multiple Sclerosis-Associated Retrovirus Envelope Protein by Human Herpesvirus-6A and CD46 Receptor Engagement

scientific article published on 06 December 2018

Inflammatory response of endothelial cells to a human endogenous retrovirus associated with multiple sclerosis is mediated by TLR4.

scientific article

Infrequency of detection of particle-associated MSRV/HERV-W RNA in the synovial fluid of patients with rheumatoid arthritis

scientific article published on 01 September 2000

Isolation of retrovirus from patients with multiple sclerosis

scientific article published in April 1991

Leptomeningeal cell line from multiple sclerosis with reverse transcriptase activity and viral particles

scientific article published in November 1989

MSRV envelope protein is a potent, endogenous and pathogenic agonist of human toll-like receptor 4: Relevance of GNbAC1 in multiple sclerosis treatment

scientific article published on 11 December 2015

MSRV, Syncytin and the role of endogenous retroviral proteins in demyelination

scientific article published on 01 April 2005

Meeting report: "Human endogenous retroviruses: HERVs or transposable elements in autoimmune, chronic inflammatory and degenerative diseases or cancer", Lyon, France, november 5th and 6th 2019 - an MS scientist's digest

scientific article published on 08 April 2020

Molecular characteristics of Human Endogenous Retrovirus type-W in schizophrenia and bipolar disorder.

scientific article published on 4 December 2012

Molecular characteristics of Human Endogenous Retrovirus type-W in schizophrenia and bipolar disorder.

scientific article

Molecular characterization and placental expression of HERV-W, a new human endogenous retrovirus family.

scientific article

Molecular cloning and characterization of MSRV-related sequences associated with retrovirus-like particles

scientific article published on July 1999

Molecular identification of a novel retrovirus repeatedly isolated from patients with multiple sclerosis. The Collaborative Research Group on Multiple Sclerosis

scientific article published on July 1997

Multiple sclerosis retrovirus particles and recombinant envelope trigger an abnormal immune response in vitro, by inducing polyclonal Vbeta16 T-lymphocyte activation

scientific article published on 01 September 2001

Multiple sclerosis-associated retroviral agent (MSRV)-stimulated cytokine production in patients with relapsing-remitting multiple sclerosis.

scientific article published on 27 February 2009

Multiple sclerosis-associated retrovirus and related human endogenous retrovirus-W in patients with multiple sclerosis.

scientific article published on 6 December 2013

Multiple sclerosis-associated retrovirus particles cause T lymphocyte-dependent death with brain hemorrhage in humanized SCID mice model

scientific article published in February 2003

Phylogeny of a novel family of human endogenous retrovirus sequences, HERV-W, in humans and other primates

scientific article (publication date: 20 November 1999)

Preclinical and early clinical development of GNbAC1, a humanized IgG4 monoclonal antibody targeting endogenous retroviral MSRV-Env protein

scientific article

Prehistoric enemies within: The contribution of human endogenous retroviruses to neurological diseases. Meeting report: "Second International Workshop on Human Endogenous Retroviruses and Disease", Washington DC, March 13th and 14th 2017.

scientific article published in May 2017

Re: Errors in the editorial by Christensen and Giovannoni [HERVs: have we been here before? MSJ 18(12) 1670-1672].

scientific article

Reduced expression of human endogenous retrovirus (HERV)-W GAG protein in the cingulate gyrus and hippocampus in schizophrenia, bipolar disorder, and depression

scientific article published on 15 January 2007

Regulation of human endogenous retrovirus W protein expression by herpes simplex virus type 1: implications for multiple sclerosis

scientific article published in February 2006

Reply to Ruprecht and Mayer: Unearthing genomic fossils in the pathogenesis of multiple sclerosis

scientific article published on 27 August 2019

Rescuing the negative impact of human endogenous retrovirus envelope protein on oligodendroglial differentiation and myelination

scientific article published on 14 November 2018

Specificities of multiple sclerosis cerebrospinal fluid and serum antibodies against mimotopes

scientific article

Sporadic ALS/MND: a global neurodegeneration with retroviral involvement?

scientific article published in May 1995

The DNA copy number of human endogenous retrovirus-W (MSRV-type) is increased in multiple sclerosis patients and is influenced by gender and disease severity

scientific article

The envelope of human endogenous retrovirus in neuro-inflammation

The envelope protein of a human endogenous retrovirus-W family activates innate immunity through CD14/TLR4 and promotes Th1-like responses

scientific article published on 01 June 2006

The human endogenous retrovirus link between genes and environment in multiple sclerosis and in multifactorial diseases associating neuroinflammation

scientific article published on August 2010

The multiple sclerosis-associated retrovirus and its HERV-W endogenous family: a biological interface between virology, genetics, and immunology in human physiology and disease

scientific article

The neutralizing antibody GNbAC1 abrogates HERV-W envelope protein-mediated oligodendroglial maturation blockade

scientific article published on 5 December 2014

Treatment against human endogenous retrovirus: a possible personalized medicine approach for multiple sclerosis

scientific article published on 16 September 2015

Variation in proviral content among human genomes mediated by LTR recombination

scholarly article by Jainy Thomas published in January 2018

[DNA sequences from mobile genetic elements, a hidden half of the human genome].

scientific article published on 27 February 2017

pHERV-W envelope protein fuels microglial cell-dependent damage of myelinated axons in multiple sclerosis

scientific article published on 18 June 2019

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