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List of works by Colin L. Masters

(18)F-Florbetaben PET beta-amyloid binding expressed in Centiloids

scientific article published on 22 June 2017

11C-PiB PET ABri imaging in Worster-Drought syndrome (familial British dementia): a case report

scientific article published on January 2010

A Conceptualization of the Utility of Subjective Cognitive Decline in Clinical Trials of Preclinical Alzheimer's Disease

scientific article published on 11 August 2016

A Multi-Cohort Study of ApoE ɛ4 and Amyloid-β Effects on the Hippocampus in Alzheimer's Disease

scientific article published on January 2017

A Polygenic Risk Score Derived From Episodic Memory Weighted Genetic Variants Is Associated With Cognitive Decline in Preclinical Alzheimer's Disease

scientific article published on 19 December 2018

A Randomized Controlled Trial of Adherence to a 24-Month Home-Based Physical Activity Program and the Health Benefits for Older Adults at Risk of Alzheimer's Disease: The AIBL Active-Study

scientific article published on 01 January 2019

A blood-based biomarker panel indicates IL-10 and IL-12/23p40 are jointly associated as predictors of β-amyloid load in an AD cohort

scientific article published on 25 October 2017

A classification algorithm for predicting progression from normal cognition to mild cognitive impairment across five cohorts: The preclinical AD consortium

scientific article

A domain level interaction network of amyloid precursor protein and Abeta of Alzheimer's disease

scientific article published on June 2010

A harmonized longitudinal biomarkers and cognition database for assessing the natural history of preclinical Alzheimer's disease from young adulthood and for designing prevention trials

scientific article published on 07 September 2019

A manganese-superoxide dismutase/catalase mimetic extends survival in a mouse model of human prion disease

scientific article published on 16 April 2008

A normalisation framework for quantitative brain imaging; application to quantitative susceptibility mapping

A novel epsilon-cleavage within the transmembrane domain of the Alzheimer amyloid precursor protein demonstrates homology with Notch processing

scientific article published in February 2002

A pilot study of the utility of cerebrospinal fluid neurofilament light chain in differentiating neurodegenerative from psychiatric disorders: A 'C-reactive protein' for psychiatrists and neurologists?

scientific article published on 21 June 2019

A plasma protein classifier for predicting amyloid burden for preclinical Alzheimer's disease

scientific article published on 06 February 2019

A primer of amyloid nomenclature

scientific article (publication date: September 2007)

A randomized, exploratory molecular imaging study targeting amyloid β with a novel 8-OH quinoline in Alzheimer's disease: The PBT2-204 IMAGINE study

scientific article published on 9 November 2017

A rigorous method to enrich for exosomes from brain tissue

scientific article published on 26 July 2017

A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer's disease

scientific article published on 11 March 2020

A surface based approach for cortical thickness comparison between PiB+ and PiB- healthy control subjects

A survey of attitudes toward clinical trials and genetic disclosure in autosomal dominant Alzheimer's disease

scientific article published on 22 July 2015

A systemic view of Alzheimer disease - insights from amyloid-β metabolism beyond the brain

scientific article published on 13 October 2017

A systemic view of Alzheimer disease - insights from amyloid-β metabolism beyond the brain

scientific article published in September 2017

A voxel-based morphometry study of volumetric MRI in familial Alzheimer's disease

A web‐based normative data tool for assessing cognitive performance in healthy older Australians ⬇️

scientific article published on February 21, 2011

APOE ε4 moderates amyloid-related memory decline in preclinical Alzheimer's disease

scientific article published on 11 December 2014

APOEɛ4 Genotype, Amyloid, and Clinical Disease Progression in Cognitively Normal Older Adults

scientific article

APP intracellular domain is increased and soluble Abeta is reduced with diet-induced hypercholesterolemia in a transgenic mouse model of Alzheimer disease

scientific article published on June 2004

ATN profiles among cognitively normal individuals and longitudinal cognitive outcomes

scientific article published on 06 March 2019

Abeta aggregation and possible implications in Alzheimer's disease pathogenesis

scientific article published on March 2009

Activation of epidermal growth factor receptor by metal-ligand complexes decreases levels of extracellular amyloid beta peptide

scientific article

Acute exposure to prion infection induces transient oxidative stress progressing to be cumulatively deleterious with chronic propagation in vitro ⬇️

scientific article published on April 3, 2011

Addressing population aging and Alzheimer's disease through the Australian imaging biomarkers and lifestyle study: collaboration with the Alzheimer's Disease Neuroimaging Initiative

scientific article published in May 2010

Advances in molecular imaging for the diagnosis of dementia

scientific article published on 29 July 2009

Advancing Alzheimer's disease diagnosis, treatment, and care: recommendations from the Ware Invitational Summit

scientific article (publication date: September 2012)

Alanine-2 carbonyl is an oxygen ligand in Cu2+ coordination of Alzheimer's disease amyloid-beta peptide--relevance to N-terminally truncated forms.

scientific article published in July 2009

Alpha-synuclein transgenic mice exhibit reduced anxiety-like behaviour

scientific article published on 4 January 2008

Alterations in dorsal and ventral posterior cingulate connectivity in APOE ε4 carriers at risk of Alzheimer's disease

scientific article

Alternative transcripts of presenilin-1 associated with frontotemporal dementia

scientific article

Alzheimer disease: the landscape of ageing--insights from AD imaging markers

scientific article published on 4 November 2014

Alzheimer's Aβ peptides with disease-associated N-terminal modifications: influence of isomerisation, truncation and mutation on Cu2+ coordination

scientific article

Alzheimer's Disease Normative Cerebrospinal Fluid Biomarkers Validated in PET Amyloid-β Characterized Subjects from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study

scientific article published on August 2015

Alzheimer's Disease and the Early Signs of Age-Related Macular Degeneration

scientific article published on 2 June 2016

Alzheimer's Disease: A Journey from Amyloid Peptides and Oxidative Stress, to Biomarker Technologies and Disease Prevention Strategies-Gains from AIBL and DIAN Cohort Studies

scientific article published in January 2018

Alzheimer's centennial legacy: prospects for rational therapeutic intervention targeting the Abeta amyloid pathway

scientific article published on 29 September 2006

Alzheimer's disease amyloid beta and prion protein amyloidogenic peptides promote macrophage survival, DNA synthesis and enhanced proliferative response to CSF-1 (M-CSF).

scientific article published in June 2002

Alzheimer's disease amyloid precursor protein (ApPP): proteolytic processing, secretases and βA4 amyloid production

article

Alzheimer's disease-associated presenilin 1 in neuronal cells: Evidence for localization to the endoplasmic reticulum-Golgi intermediate compartment

Ammonium hydroxide treatment of Aβ produces an aggregate free solution suitable for biophysical and cell culture characterization ⬇️

scientific article published on May 7, 2013

Among vitamin B12 deficient older people, high folate levels are associated with worse cognitive function: combined data from three cohorts

scientific article

Amyloid burden and incident depressive symptoms in cognitively normal older adults

scientific article published on 25 April 2016

Amyloid burden and incident depressive symptoms in preclinical Alzheimer's disease.

scientific article published on 3 January 2018

Amyloid fibril protein nomenclature -- 2002.

scientific article

Amyloid imaging in Alzheimer's disease and other dementias

scientific article published on 7 April 2009

Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging

scientific article published on 15 May 2010

Amyloid imaging with (18)F-florbetaben in Alzheimer disease and other dementias

scientific article published on 15 July 2011

Amyloid precursor protein processing and retinal pathology in mouse models of Alzheimer's disease

scientific article published on 7 March 2009

Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study

scientific article

Amyloid β-associated cognitive decline in the absence of clinical disease progression and systemic illness

scientific article published on 9 June 2017

Amyloid-Related Memory Decline in Preclinical Alzheimer's Disease Is Dependent on APOE ε4 and Is Detectable over 18-Months

scientific article published on 2 October 2015

Amyloid-beta peptide disruption of lipid membranes and the effect of metal ions

scientific article published on 20 December 2005

Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope

scientific article

Amyloid-β Peptide Aβ3pE-42 Induces Lipid Peroxidation, Membrane Permeabilization, and Calcium Influx in Neurons

scientific article published on 23 December 2015

Amyloid-β, anxiety, and cognitive decline in preclinical Alzheimer disease: a multicenter, prospective cohort study

scientific article

Amyloid-β: the seeds of darkness

scientific article published on 11 May 2011

An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations

scientific article published on 07 October 2019

An increased neutrophil-lymphocyte ratio in Alzheimer's disease is a function of age and is weakly correlated with neocortical amyloid accumulation

scientific article

An iron–dopamine index predicts risk of parkinsonian neurodegeneration in the substantia nigra pars compacta

article

Anionic phospholipid interactions of the prion protein N terminus are minimally perturbing and not driven solely by the octapeptide repeat domain

scientific article published on 2 August 2010

Anxiety symptoms, cerebral amyloid burden and memory decline in healthy older adults without dementia: 3-year prospective cohort study

scientific article published on 13 February 2014

Apolipoprotein C-II Adopts Distinct Structures in Complex with Micellar and Submicellar Forms of the Amyloid-Inhibiting Lipid-Mimetic Dodecylphosphocholine

scientific article published on January 2016

Apolipoprotein D levels are elevated in prefrontal cortex of subjects with Alzheimer's disease: no relation to apolipoprotein E expression or genotype

scientific article (publication date: 15 July 2003)

Apolipoprotein D levels are elevated in prefrontal cortex of subjects with Alzheimer’s disease

Are early atrophy patterns in autosomal dominant familial Alzheimer's disease gene-dependent?

article

Association of plasma Aß peptides with blood pressure in the elderly

scientific article (publication date: 15 April 2011)

Association of β-Amyloid and Apolipoprotein E ε4 With Memory Decline in Preclinical Alzheimer Disease.

scientific article published on 22 January 2018

Associations of neighborhood environment with brain imaging outcomes in the Australian Imaging, Biomarkers and Lifestyle cohort

scientific article published on 18 August 2016

Atrophy, hypometabolism and clinical trajectories in patients with amyloid-negative Alzheimer's disease.

scientific article published on 29 June 2016

Autobiographical narratives relate to Alzheimer's disease biomarkers in older adults

scientific article published on 27 June 2014

Automated (11)C-PiB standardized uptake value ratio

scientific article

Autosomal Dominantly Inherited Alzheimer Disease: Analysis of genetic subgroups by Machine Learning

scientific article published on 07 January 2020

Avoiding methodological bias in studies of amyloid imaging results disclosure.

scientific article published on 4 June 2019

Awareness of genetic risk in the Dominantly Inherited Alzheimer Network (DIAN)

scientific article published on 01 January 2020

Aβ Imaging: feasible, pertinent, and vital to progress in Alzheimer's disease

scientific article published in February 2012

Aβ amyloid, cognition, and APOE genotype in healthy older adults

scientific article published on 14 November 2012

Aβ and cognitive change: examining the preclinical and prodromal stages of Alzheimer's disease

scientific article published on 28 February 2014

Aβ imaging with 18F-florbetaben in prodromal Alzheimer's disease: a prospective outcome study

scientific article

Aβ-amyloid and Tau Imaging in Dementia

scientific article published on 13 October 2016

Aβ-related memory decline in APOE ε4 noncarriers: Implications for Alzheimer disease

scientific article

BACE: Therapeutic target and potential biomarker for Alzheimer's disease ⬇️

scientific article published on September 15, 2010

BDNF Val66Met in preclinical Alzheimer's disease is associated with short-term changes in episodic memory and hippocampal volume but not serum mBDNF.

scientific article

BDNF Val66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer's disease

scientific article

BDNF Val66Met, Aβ amyloid, and cognitive decline in preclinical Alzheimer's disease

scientific article published on 12 June 2013

Baseline Amnestic Severity Predicts Progression From Amnestic Mild Cognitive Impairment to Alzheimer Disease Dementia at 3 Years

scientific article published on 20 March 2018

Bayesian graphical network analyses reveal complex biological interactions specific to Alzheimer's disease

scientific article published in January 2015

Behavioural phenotype of APPC100.V717F transgenic mice over-expressing a mutant Abeta-bearing fragment is associated with reduced NMDA receptor density

scientific article

Beta-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease

scientific article published on 10 October 2007

Biochemically-defined pools of amyloid-β in sporadic Alzheimer's disease: correlation with amyloid PET.

scientific article published on 5 March 2017

Biochemistry of amyloid β-protein and amyloid deposits in Alzheimer disease

scientific article published on June 2012

Blood Borne Aβ Dimer Correlates With Clinical Markers of Alzheimer's Disease

scholarly article by Kevin J. Barnham et al published July 2009 in Alzheimer's and Dementia

Blood-Based Protein Biomarkers for Diagnosis of Alzheimer Disease ⬇️

scientific article published on October 1, 2012

Blood-based biomarkers for Alzheimer disease: mapping the road to the clinic

scientific article published on 01 November 2018

Brain and hippocampal rates of atrophy in familial Alzheimer's disease mutation carriers: Preliminary findings from the DIAN study

Buccal Cell Cytokeratin 14 Correlates with Multiple Blood Biomarkers of Alzheimer's Disease Risk

scientific article published in September 2015

C-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress

scientific article

C-terminal peptides modelling constitutive PrPC processing demonstrate ameliorated toxicity predisposition consequent to α-cleavage

scientific article

C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1.

scientific article published on 25 September 2006

CSF Tau supplements 14-3-3 protein detection for sporadic Creutzfeldt-Jakob disease diagnosis while transitioning to next generation diagnostics

scientific article published on 5 February 2018

CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline

scholarly article by Marc Suárez-Calvet et al published December 2018 in EMBO Molecular Medicine

CapAIBL: Automated Reporting of Cortical PET Quantification Without Need of MRI on Brain Surface Using a Patch-Based Method

Catching the culprit prion

scientific article published in Nature

Cerebral amyloidosis associated with cognitive decline in autosomal dominant Alzheimer disease

scientific article

Cerebral microbleeds: a review of clinical, genetic, and neuroimaging associations

scientific article published on 06 January 2014

Cerebral quantitative susceptibility mapping predicts amyloid-β-related cognitive decline

Cerebrospinal fluid neurofilament light chain is elevated in Niemann-Pick type C compared to psychiatric disorders and healthy controls and may be a marker of treatment response

scientific article published on 11 December 2019

Cerebrospinal fluid neurofilament light concentration predicts brain atrophy and cognition in Alzheimer's disease

scientific article published on 27 February 2020

Changes in plasma amyloid beta in a longitudinal study of aging and Alzheimer's disease

scientific article published on 13 March 2013

Changes in the plasma proteome at asymptomatic and symptomatic stages of autosomal dominant Alzheimer's disease

scientific article published on 06 July 2016

Characterisation of the effect of knockout of the amyloid precursor protein on outcome following mild traumatic brain injury

scientific article published on 28 February 2012

Characterization and Identification of Dityrosine Cross-Linked Peptides Using Tandem Mass Spectrometry

scientific article published on 28 April 2017

Characterization of PiB binding to white matter in Alzheimer disease and other dementias

scientific article published on 21 January 2009

Characterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations

scientific article

Characterization of the metal status of natively purified alpha-synuclein from human blood, brain tissue, or recombinant sources using size exclusion ICP-MS reveals no significant binding of Cu, Fe or Zn

scientific article published on 01 January 2019

Characterizing bathocuproine self-association and subsequent binding to Alzheimer's disease amyloid beta-peptide by NMR.

scientific article

Cholesterol and Clioquinol modulation of A beta(1-42) interaction with phospholipid bilayers and metals

scientific article published on 8 September 2007

Chronic exposure to U18666A is associated with oxidative stress in cultured murine cortical neurons

scientific article published on 12 June 2006

Chronic exposure to high levels of zinc or copper has little effect on brain metal homeostasis or Abeta accumulation in transgenic APP-C100 mice

scientific article published on 21 April 2009

Clinical and biomarker changes in dominantly inherited Alzheimer's disease

scientific article

Clinical and cognitive trajectories in cognitively healthy elderly individuals with suspected non-Alzheimer's disease pathophysiology (SNAP) or Alzheimer's disease pathology: a longitudinal study.

scientific article published on 19 July 2016

Clinical meaningfulness of subtle cognitive decline on longitudinal testing in preclinical AD

scientific article published on 04 January 2020

Clinical utility of the cogstate brief battery in identifying cognitive impairment in mild cognitive impairment and Alzheimer's disease

scientific article

Clinical, pathophysiological and genetic features of motor symptoms in autosomal dominant Alzheimer's disease

scientific article published on 01 May 2019

Clioquinol inhibits peroxide-mediated toxicity through up-regulation of phosphoinositol-3-kinase and inhibition of p53 activity

scientific article published on 17 November 2007

Cognition and beta-amyloid in preclinical Alzheimer's disease: data from the AIBL study

scientific article

Cognitive consequences of high Aβ amyloid in mild cognitive impairment and healthy older adults: implications for early detection of Alzheimer's disease

scientific article

Cognitive decline in adults with amnestic mild cognitive impairment and high amyloid-β: prodromal Alzheimer's disease?

scientific article published in January 2013

Cognitive impairment and decline in cognitively normal older adults with high amyloid-β: A meta-analysis

scientific article published on 18 October 2016

Comparative analysis of the Cancer Council of Victoria and the online Commonwealth Scientific and Industrial Research Organisation FFQ.

scientific article published on 18 September 2015

Comparing cortical signatures of atrophy between late-onset and autosomal dominant Alzheimer disease

scientific article published on 05 November 2020

Comparison of 11C-PiB and 18F-florbetaben for Aβ imaging in ageing and Alzheimer's disease

scientific article published on 8 March 2012

Comparison of 18F-florbetaben quantification results using the standard Centiloid, MR-based, and MR-less CapAIBL® approaches: Validation against histopathology

scientific article published on 14 May 2019

Comparison of Pittsburgh compound B and florbetapir in cross-sectional and longitudinal studies

article

Comparison of amyloid PET measured in Centiloid units with neuropathological findings in Alzheimer's disease

scientific article published on 04 March 2020

Concentration dependent Cu2+ induced aggregation and dityrosine formation of the Alzheimer's disease amyloid-beta peptide

scientific article published on 13 February 2007

Concordance Between Cerebrospinal Fluid Biomarkers with Alzheimer's Disease Pathology Between Three Independent Assay Platforms

scientific article

Concordant peripheral lipidome signatures in two large clinical studies of Alzheimer's disease

scientific article published on 10 November 2020

Copper Coordination by Familial Mutants of Parkinson’s Disease-Associated α-Synuclein

scholarly article by Simon C. Drew et al published 20 October 2009 in Applied Magnetic Resonance

Copper promotes the trafficking of the amyloid precursor protein

scientific article

Copper, beta-amyloid, and Alzheimer's disease: tapping a sensitive connection

scientific article

Copper-dependent inhibition of cytochrome c oxidase by Abeta(1-42) requires reduced methionine at residue 35 of the Abeta peptide

scientific article published in October 2006

Copper-mediated amyloid-beta toxicity is associated with an intermolecular histidine bridge

scientific article

Correction: Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group

scientific article published on 20 September 2016

Corrigendum: Corrigendum to 'Self and informant memory concerns align in healthy memory complainers and in early stages of mild cognitive impairment but separate with increasing cognitive impairment'.

scientific article published on 11 July 2016

Cortical surface mapping using topology correction, partial flattening and 3D shape context-based non-rigid registration for use in quantifying atrophy in Alzheimer's disease

scientific article published on 29 December 2011

Creutzfeldt-Jakob disease surveillance in Australia January 1970 to December 2003.

scientific article published in January 2004

Creutzfeldt-Jakob disease surveillance in Australia: update to 31 December 2018

scientific article published on 15 August 2019

Creutzfeldt-Jakob disease surveillance in Australia: update to December 2014.

scientific article

Creutzfeldt-Jakob disease surveillance in Australia: update to December 2015.

scientific article

Creutzfeldt-Jakob disease: Australian surveillance update to 31 December 2004.

scientific article

Creutzfeldt-Jakob disease: Australian surveillance update to December 2005.

scientific article published in January 2006

Creutzfeldt-Jakob disease: Australian surveillance update to March 2007.

scientific article published in June 2007

Creutzfeldt–Jakob disease surveillance in Australia: update to December 2017

scientific article published on 16 July 2019

Cross-sectional and longitudinal analysis of the relationship between Aβ deposition, cortical thickness, and memory in cognitively unimpaired individuals and in Alzheimer disease.

scientific article

Cross-sectional cerebral volumetric differences and associations with estimated time to age-at-onset in familial Alzheimer's disease: Findings from the DIAN study

article

Crystal Structure of the Amyloid-β p3 Fragment Provides a Model for Oligomer Formation in Alzheimer's Disease ⬇️

scientific article published on January 26, 2011

Crystallization and preliminary crystallographic studies of the copper-binding domain of the amyloid precursor protein of Alzheimer's disease

scientific article

Cu2+-induced modification of the kinetics of A beta(1-42) channels

scientific article published on 18 June 2003

Cytosolic beta-amyloid deposition and supranuclear cataracts in lenses from people with Alzheimer's disease

scientific article

DIFFERENCE IN THE RATE OF COGNITIVE CHANGE BETWEEN INDIVIDUALS WITH AND WITHOUT VASCULAR RISK FACTORS: A LONGITUDINAL STUDY

Decline in cognitive function over 18 months in healthy older adults with high amyloid-β.

scientific article

Decrease in p3-Alcβ37 and p3-Alcβ40, products of Alcadein β generated by γ-secretase cleavages, in aged monkeys and patients with Alzheimer's disease

scientific article published on 07 November 2019

Decreased body mass index in the preclinical stage of autosomal dominant Alzheimer's disease

scientific article

Decreased copper in Alzheimer's disease brain is predominantly in the soluble extractable fraction

scientific article published on 21 October 2013

Decreased plasma iron in Alzheimer's disease is due to transferrin desaturation

scientific article

Decreased serum zinc is an effect of ageing and not Alzheimer's disease.

scientific article published in July 2014

Degradation of the Alzheimer disease amyloid beta-peptide by metal-dependent up-regulation of metalloprotease activity

scientific article published on 28 April 2006

Delineating common molecular mechanisms in Alzheimer's and prion diseases

scientific article published on 3 July 2006

Design of non-aggregating variants of Aβ peptide

scientific article published on October 2014

Detection of prion epitopes on PrP and PrP of transmissible spongiform encephalopathies using specific monoclonal antibodies to PrP.

scientific article published in December 2005

Determining clinically meaningful decline in preclinical Alzheimer disease

scientific article published on 09 July 2019

Developing an international network for Alzheimer research: The Dominantly Inherited Alzheimer Network

scientific article (publication date: October 2012)

Development of a Platinum Complex as an anti‐Amyloid Agent for the Therapy of Alzheimer’s Disease ⬇️

scientific article published on February 10, 2013

Diacetylbis(N(4)-methylthiosemicarbazonato) copper(II) (CuII(atsm)) protects against peroxynitrite-induced nitrosative damage and prolongs survival in amyotrophic lateral sclerosis mouse model

scientific article published on 27 October 2011

Dietary patterns and cognitive decline in an Australian study of ageing

scientific article published on 29 July 2014

Differential diagnosis in Alzheimer's disease and dementia with Lewy bodies via VMAT2 and amyloid imaging

scientific article published on 17 January 2012

Dimeric structures of alpha-synuclein bind preferentially to lipid membranes

scientific article

Diverse fibrillar peptides directly bind the Alzheimer's amyloid precursor protein and amyloid precursor-like protein 2 resulting in cellular accumulation

scientific article published in March 2003

Dopamine promotes alpha-synuclein aggregation into SDS-resistant soluble oligomers via a distinct folding pathway

scientific article published on 9 June 2005

Early behavioural changes in familial Alzheimer's disease in the Dominantly Inherited Alzheimer Network

scientific article published on 15 February 2015

Effect of APOE Genotype on Amyloid Deposition, Brain Volume, and Memory in Cognitively Normal Older Individuals.

scientific article

Effect of BDNF Val66Met on memory decline and hippocampal atrophy in prodromal Alzheimer's disease: a preliminary study

scientific article

Effect of BDNFVal66Met on disease markers in dominantly inherited Alzheimer's disease

scientific article published on 25 August 2018

Effect of Metal Chelators on γ-Secretase Indicates That Calcium and Magnesium Ions Facilitate Cleavage of Alzheimer Amyloid Precursor Substrate

scientific article published on 28 December 2010

Effect of a 24-month physical activity program on brain changes in older adults at risk of Alzheimer's disease: the AIBL active trial

scientific article published on 27 May 2019

Effect of amyloid on memory and non-memory decline from preclinical to clinical Alzheimer's disease

scientific article

Effects of anticholinergic drugs on cognitive function in older Australians: results from the AIBL study

scientific article published on 9 March 2011

Elevated labile Cu is associated with oxidative pathology in Alzheimer disease

scientific article published on 24 October 2011

Enduring Elevations of Hippocampal Amyloid Precursor Protein and Iron Are Features of β-Amyloid Toxicity and Are Mediated by Tau

scientific article

Enhanced geographically restricted surveillance simulates sporadic Creutzfeldt-Jakob disease cluster

scientific article published on 28 November 2008

Enhanced toxicity and cellular binding of a modified amyloid beta peptide with a methionine to valine substitution

scientific article

Enzymatic detergent treatment protocol that reduces protease-resistant prion protein load and infectivity from surgical-steel monofilaments contaminated with a human-derived prion strain

scientific article published in October 2007

Episodic Memory and Learning Dysfunction Over an 18-Month Period in Preclinical and Prodromal Alzheimer's Disease

scientific article published on 01 January 2018

Estimates of age-related memory decline are inflated by unrecognized Alzheimer's disease

scientific article published on 11 June 2018

Evaluating atypical dementia syndromes using positron emission tomography with carbon 11 labeled Pittsburgh Compound B.

scientific article published in August 2007

Evaluation of Cholinergic Deficiency in Preclinical Alzheimer's Disease Using Pupillometry

scientific article published on 16 August 2017

Evaluation of the effects of treatment with sAPPα on functional and histological outcome following controlled cortical impact injury in mice

scientific article published on 16 March 2012

Evidence for a copper-binding superfamily of the amyloid precursor protein

scientific article (publication date: 30 July 2002)

Extended period of asymptomatic prion disease after low dose inoculation: assessment of detection methods and implications for infection control

scientific article published in November 2005

Factors associated with the onset and persistence of post-lumbar puncture headache

scientific article

Follow-up plasma apolipoprotein E levels in the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing (AIBL) cohort

scientific article

Formation of dopamine-mediated alpha-synuclein-soluble oligomers requires methionine oxidation

scientific article

Functional connectivity in autosomal dominant and late-onset Alzheimer disease

scientific article

GLOBAL TAU BURDEN CORRELATES WITH BASAL FOREBRAIN ATROPHY IN HEALTHY AGING SUBJECTS

Gender and genetic background effects on brain metal levels in APP transgenic and normal mice: implications for Alzheimer beta-amyloid pathology

scientific article published on 6 March 2006

Gene knockout of tau expression does not contribute to the pathogenesis of prion disease

scientific article published in November 2011

Genetic algorithm with logistic regression for prediction of progression to Alzheimer's disease

scientific article

Genetic heterogeneity in Alzheimer disease and implications for treatment strategies

scientific article

Glycosaminoglycan sulfation determines the biochemical properties of prion protein aggregates

scientific article published on 20 February 2015

Glycosaminoglycan sulphation affects the seeded misfolding of a mutant prion protein

scientific article

Guanidine hydrochloride denaturation of dopamine-induced α-synuclein oligomers: a small-angle X-ray scattering study

scientific article published on 31 August 2013

Habitual exercise levels are associated with cerebral amyloid load in presymptomatic autosomal dominant Alzheimer's disease

scientific article published on 11 May 2017

Harmonization of large MRI datasets for the analysis of brain imaging patterns throughout the lifespan

scientific article published on 09 December 2019

Head-to-head comparison of 11C-PiB and 18F-AZD4694 (NAV4694) for β-amyloid imaging in aging and dementia

scientific article published on 10 April 2013

High Content, Multi-Parameter Analyses in Buccal Cells to Identify Alzheimer's Disease.

scientific article

High order W02-reactive stable oligomers of amyloid-β are produced in vivo and in vitro via dialysis and filtration of synthetic amyloid-β monomer

scientific article

High performance plasma amyloid-β biomarkers for Alzheimer's disease

scientific article published on 31 January 2018

High striatal amyloid beta-peptide deposition across different autosomal Alzheimer disease mutation types

scientific article published in December 2009

Histidine 14 modulates membrane binding and neurotoxicity of the Alzheimer's disease amyloid-beta peptide

scientific article published in January 2010

Histopathology and Florbetaben PET in Patients Incorrectly Diagnosed with Alzheimer's Disease

scientific article published on 9 December 2016

Homo- and heterodimerization of APP family members promotes intercellular adhesion

scientific article

Homocysteine, vitamin B12, and folic acid levels in Alzheimer's disease, mild cognitive impairment, and healthy elderly: baseline characteristics in subjects of the Australian Imaging Biomarker Lifestyle study

scientific article published in January 2011

Iatrogenic Creutzfeldt–Jakob disease in Australia: time to amend infection control measures for pituitary hormone recipients? ⬇️

scientific article published on September 20, 2010

Imaging of amyloid beta in Alzheimer's disease with 18F-BAY94-9172, a novel PET tracer: proof of mechanism

scientific article

Imaging of tau deposits in adults with Niemann-Pick type C disease: a case-control study

scientific article published on 28 January 2019

Imaging tau and amyloid-β proteinopathies in Alzheimer disease and other conditions

scientific article published on 16 February 2018

Impact of Mild Head Injury on Neuropsychological Performance in Healthy Older Adults: Longitudinal Assessment in the AIBL Cohort

scientific article published on 12 May 2016

Implementing the centiloid transformation for 11C-PiB and β-amyloid 18F-PET tracers using CapAIBL

scientific article published on 18 August 2018

In vitro characterisation of BF227 binding to alpha-synuclein/Lewy bodies.

scientific article

In vitro characterization of [18F]-florbetaben, an Aβ imaging radiotracer

scientific article published on 11 April 2012

In vitro gamma-secretase cleavage of the Alzheimer's amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc

scientific article published in November 2005

In vivo evaluation of a novel tau imaging tracer for Alzheimer's disease.

scientific article published on 11 February 2014

Incidence of cerebral microbleeds in preclinical Alzheimer disease

scientific article published on 12 March 2014

Increased Carbohydrate Intake is Associated with Poorer Performance in Verbal Memory and Attention in an APOE Genotype-Dependent Manner.

scientific article published on 03 April 2017

Increased cerebral blood flow with increased amyloid burden in the preclinical phase of alzheimer's disease

scientific article published on 30 May 2019

Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease

scientific article

Increased proportions of C1 truncated prion protein protect against cellular M1000 prion infection

scientific article published on October 2009

Increasing Cu bioavailability inhibits Abeta oligomers and tau phosphorylation

scholarly article

Increasing the Predictive Accuracy of Amyloid-β Blood-Borne Biomarkers in Alzheimer's Disease ⬇️

scientific article published on January 1, 2011

Independent contribution of temporal β-amyloid deposition to memory decline in the pre-dementia phase of Alzheimer’s disease ⬇️

scientific article published on February 9, 2011

Influence of Comorbidity of Cerebrovascular Disease and Amyloid-β on Alzheimer's Disease

scientific article published on 01 January 2020

Inhibition of gamma-secretase as a therapeutic intervention for Alzheimer's disease: prospects, limitations and strategies

scientific article published in January 2006

Inhibition of gamma-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes

scientific article published on 2 January 2008

Innate phagocytosis by peripheral blood monocytes is altered in Alzheimer's disease

scientific article

Insulin resistance is associated with reductions in specific cognitive domains and increases in CSF tau in cognitively normal adults.

scientific article published on 29 August 2017

Intensity of human prion disease surveillance predicts observed disease incidence

scientific article published on 21 August 2013

Interaction of the molecular chaperone alphaB-crystallin with alpha-synuclein: effects on amyloid fibril formation and chaperone activity

scientific article published in July 2004

Intracellular amyloid formation in muscle cells of Abeta-transgenic Caenorhabditis elegans: determinants and physiological role in copper detoxification

scientific article

Investigating Alzheimer's disease in the blood cellular fraction

scholarly article by Andrew Watt et al published July 2011 in Alzheimer's and Dementia

Investigating copper-regulated protein expression in Menkes fibroblasts using antibody microarrays

scientific article

Investigation of matrix metalloproteinases, MMP-2 and MMP-9, in plasma reveals a decrease of MMP-2 in Alzheimer's disease

scientific article published in January 2011

Iron inhibits neurotoxicity induced by trace copper and biological reductants

scientific article published on 3 February 2004

Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease

scientific article

KIBRA is associated with accelerated cognitive decline and hippocampal atrophy in APOE ε4-positive cognitively normal adults with high Aβ-amyloid burden

scientific article published in February 2018

Klotho allele status is not associated with Aβ and APOE ε4-related cognitive decline in preclinical Alzheimer's disease

scientific article published on 06 January 2019

Lack of reliable evidence for a distinctive ε4-related cognitive phenotype that is independent from clinical diagnostic status: findings from the Australian Imaging, Biomarkers and Lifestyle Study

scientific article published on 3 June 2013

Larger temporal volume in elderly with high versus low beta-amyloid deposition

scientific article published on 25 August 2010

Laser ablation-inductively coupled plasma-mass spectrometry imaging of white and gray matter iron distribution in Alzheimer's disease frontal cortex

scientific article

Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease

scientific article published on 15 February 2018

Linker histone H1 binds to disease associated amyloid-like fibrils

scientific article

Longitudinal analysis of serum copper and ceruloplasmin in Alzheimer's disease

scientific article published in January 2013

Longitudinal assessment of Aβ and cognition in aging and Alzheimer disease

scientific article

Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease

scientific article

Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease

scientific article published on 14 September 2018

Longitudinal cognitive decline in the AIBL cohort: The role of APOE ε4 status

scientific article published on 20 June 2015

Lyodura use and the risk of iatrogenic Creutzfeldt-Jakob disease in Australia

scientific article published in February 2004

MR-less surface-based amyloid assessment based on 11C PiB PET

scientific article

MRI signatures of brain age and disease over the lifespan based on a deep brain network and 14 468 individuals worldwide

scientific article published on 27 June 2020

Magnetic Resonance Imaging of Vascular Contributions to Cognitive Impairment and Dementia

scientific article

Magnetic Resonance Studies of β-Amyloid Peptides

Manganese chelation therapy extends survival in a mouse model of M1000 prion disease

scientific article published on 23 April 2010

Mechanisms of A beta mediated neurodegeneration in Alzheimer's disease

scientific article published on August 2007

Mechanisms of peripheral microvascular dysfunction in transgenic mice overexpressing the Alzheimer's disease amyloid Abeta protein

scientific article

Mediterranean diet adherence and rate of cerebral Aβ-amyloid accumulation: Data from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing

article

Membrane interactions and the effect of metal ions of the amyloidogenic fragment Abeta(25-35) in comparison to Abeta(1-42).

scientific article published on 22 May 2007

Metal ions, pH, and cholesterol regulate the interactions of Alzheimer's disease amyloid-beta peptide with membrane lipid

scientific article published on 14 November 2002

Metal-protein attenuating compounds and Alzheimer's disease

scientific article

Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial

scientific article

Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2).

scientific article published on 20 August 2002

Metalloproteomics: principles, challenges and applications to neurodegeneration

scientific article published on 18 July 2013

Metals and amyloid-beta in Alzheimer's disease

scientific article

Methionine oxidation: Implications for the mechanism of toxicity of the β-amyloid peptide from Alzheimer's disease

article

Methionine regulates copper/hydrogen peroxide oxidation products of Abeta

scientific article published in June 2005

Method comparison study of the Elecsys® β-Amyloid (1-42) CSF assay versus comparator assays and LC-MS/MS

scientific article published on 23 May 2019

Methylation of the imidazole side chains of the Alzheimer disease amyloid-beta peptide results in abolition of superoxide dismutase-like structures and inhibition of neurotoxicity

scientific article published on 24 January 2005

Mitochondrial oxidative stress causes hyperphosphorylation of tau.

scientific article

Mixed ligand Cu2+ complexes of a model therapeutic with Alzheimer's amyloid-β peptide and monoamine neurotransmitters

scientific article published on 28 March 2013

Modulation of Retinal Arteriolar Central Reflection by APOE genotype

scientific article

Molecular dissection of the interaction between amyloid precursor protein and its neuronal trafficking receptor SorLA/LR11.

scientific article published in February 2006

Molecular mechanisms for Alzheimer's disease: implications for neuroimaging and therapeutics

scientific article

Mouse-adapted sporadic human Creutzfeldt-Jakob disease prions propagate in cell culture

scientific article

Multisite study of the relationships between antemortem [C]PIB-PET Centiloid values and postmortem measures of Alzheimer's disease neuropathology

article

Neurodegenerative diseases and oxidative stress

scientific article published in March 2004

Neurological manifestations of autosomal dominant familial Alzheimer's disease: a comparison of the published literature with the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS).

scientific article

Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein

scientific article

Neurotoxic, redox-competent Alzheimer's beta-amyloid is released from lipid membrane by methionine oxidation

scientific article

Neurotoxicity from glutathione depletion is mediated by Cu-dependent p53 activation

scientific article published on 15 September 2007

Nicastrin expression in mouse peripheral tissues is not co-ordinated with presenilin and is high in muscle

scientific article published on October 2004

No evidence for prion protein gene locus multiplication in Creutzfeldt-Jakob disease

scientific article published on 25 January 2010

Non-invasive in vivo hyperspectral imaging of the retina for potential biomarker use in Alzheimer's disease

scientific article published on 17 September 2019

Novel Statistically-Derived Composite Measures for Assessing the Efficacy of Disease-Modifying Therapies in Prodromal Alzheimer's Disease Trials: An AIBL Study

scientific article published on June 2015

Ocular Biomarkers of Alzheimer's Disease: The Role of Anterior Eye and Potential Future Directions

scientific article published on 01 July 2018

Olfactory deficits and amyloid-β burden in Alzheimer's disease, mild cognitive impairment, and healthy aging: a PiB PET study

scientific article published on January 2010

Oligodendrocytes from neural stem cells express alpha-synuclein: increased numbers from presenilin 1 deficient mice

scientific article published in July 2002

Optical imaging detects apoptosis in the brain and peripheral organs of prion-infected mice

scientific article published in February 2011

Overexpression of Abeta is associated with acceleration of onset of motor impairment and superoxide dismutase 1 aggregation in an amyotrophic lateral sclerosis mouse model

scientific article

Overexpression of Alzheimer's disease amyloid-beta opposes the age-dependent elevations of brain copper and iron

scientific article published on 4 September 2002

Overview and recent advances in neuropathology. Part 2: Neurodegeneration

scientific article published on February 2011

P1-153: The relationship between olfactory identification and memory and Abeta burden in Alzheimer's disease, mild cognitive impairment and healthy aging: A PIB-PET study

scholarly article by Alex Bahar-Fuchs et al published July 2008 in Alzheimer's and Dementia

P2-006: Baseline data from a multi-centre, prospective longitudinal study of ageing in 1000 volunteers (the AIBL study)

P3-187 Mutagenesis-toxicity studies of the amyloid beta peptide of Alzheimer's disease

article

P4-241 The mechanism by which Aβ produces hydrogen peroxide and its role in neurotoxicity

P4-419 Clioquinol targets metallated abeta in human Alzheimer's and TG2576 mouse brains

PBT2 rapidly improves cognition in Alzheimer's Disease: additional phase II analyses

scientific article published in January 2010

Paradoxical condensation of copper with elevated beta-amyloid in lipid rafts under cellular copper deficiency conditions: implications for Alzheimer disease

scientific article published on 19 June 2009

Pathogenic mutations within the hydrophobic domain of the prion protein lead to the formation of protease-sensitive prion species with increased lethality

scientific article published on 18 December 2013

Pathways to the discovery of the Abeta amyloid of Alzheimer's disease.

scientific article published in January 2006

Performance on the Cogstate Brief Battery Is Related to Amyloid Levels and Hippocampal Volume in Very Mild Dementia.

scientific article published in September 2016

Peripheral α-defensins 1 and 2 are elevated in Alzheimer's disease

scientific article

Personal memory function in mild cognitive impairment and subjective memory complaints: results from the Australian Imaging, Biomarkers, and Lifestyle (AIBL) Study of Ageing

scientific article published on January 2014

Pharmacotherapeutic targets in Alzheimer's disease

scientific article

Phenomenological characterization of memory complaints in preclinical and prodromal Alzheimer's disease

scientific article

Plant poisoning leads to alpha-synucleinopathy and neuromelanopathy in kangaroos

scientific article published on 13 November 2019

Plasma Cortisol, Brain Amyloid-β, and Cognitive Decline in Preclinical Alzheimer's Disease: A 6-Year Prospective Cohort Study

scientific article published on 07 September 2016

Plasma Phospholipid and Sphingolipid Alterations in Presenilin1 Mutation Carriers: A Pilot Study

scientific article published on 21 January 2016

Plasma alpha-synuclein is decreased in subjects with Parkinson's disease

scientific article

Plasma amyloid beta42 and amyloid beta40 levels are associated with early cognitive dysfunction after cardiac surgery

scientific article published in November 2009

Plasma amyloid β 42/40 ratios as biomarkers for amyloid β cerebral deposition in cognitively normal individuals

scientific article published on 12 September 2017

Plasma amyloid-beta as a biomarker in Alzheimer's disease: the AIBL study of aging

scientific article

Plasma amyloid-β levels are significantly associated with a transition toward Alzheimer's disease as measured by cognitive decline and change in neocortical amyloid burden

scientific article published in January 2014

Plasma and CSF Abeta for the longitudinal prediction of Alzheimer's disease dementia and other dementias in people with cognitive decline but no dementia

scientific article

Plasma and Cerebro Spinal Fluid Amyloid Beta 42, 40 and the 42:40 ratio for diagnosis of incipient Dementia in a population with objective cognitive decline

scientific article

Plasma and Cerebro Spinal Fluid Amyloid Beta 42, 40 and the 42:40 ratio for diagnosis of incipient Dementia in a population with objective cognitive decline

scientific article (publication date: 10 November 2010)

Plasma apolipoprotein J as a potential biomarker for Alzheimer's disease: Australian Imaging, Biomarkers and Lifestyle study of aging

scientific article published on 22 December 2015

Platelet alpha- and gamma-synucleins in Parkinson's disease and normal control subjects

scientific article

Platinum-based inhibitors of amyloid-beta as therapeutic agents for Alzheimer's disease

scholarly article

Pleomorphic copper coordination by Alzheimer's disease amyloid-beta peptide

scientific article

Predicting Alzheimer disease from a blood-based biomarker profile: A 54-month follow-up

scientific article published on 17 August 2016

Predicting Alzheimer disease with β-amyloid imaging: results from the Australian imaging, biomarkers, and lifestyle study of ageing

scientific article published in December 2013

Predicting sporadic Alzheimer's disease progression via inherited Alzheimer's disease-informed machine-learning

scientific article published on 11 February 2020

Predictors of rapid cognitive decline in Alzheimer's disease: results from the Australian imaging, biomarkers and lifestyle (AIBL) study of ageing

scientific article published on 13 July 2011

Preferential degradation of cognitive networks differentiates Alzheimer's disease from ageing

scientific article published on 7 March 2018

Presymptomatic Dutch-Type Hereditary Cerebral Amyloid Angiopathy-Related Blood Metabolite Alterations

scientific article published on 24 December 2020

Presymptomatic atrophy in autosomal dominant Alzheimer's disease: A serial MRI study.

scientific article published on 21 July 2017

Profiling the iron, copper and zinc content in primary neuron and astrocyte cultures by rapid online quantitative size exclusion chromatography-inductively coupled plasma-mass spectrometry

scientific article published on 17 October 2013

Proteasome-mediated degradation of the C-terminus of the Alzheimer's disease beta-amyloid protein precursor: effect of C-terminal truncation on production of beta-amyloid protein

scientific article published in November 2003

Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets ⬇️

scientific article published on November 1, 2003

Protocol for a randomized controlled trial evaluating the effect of physical activity on delaying the progression of white matter changes on MRI in older adults with memory complaints and mild cognitive impairment: the AIBL Active trial

scientific article

Pupil response biomarkers distinguish amyloid precursor protein mutation carriers from non-carriers

scientific article published on October 2013

Pyroglutamate-Aβ: Role in the natural history of Alzheimer's disease ⬇️

scientific article published on September 15, 2010

Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group

scientific article

Quinacrine does not prolong survival in a murine Creutzfeldt-Jakob disease model

article

Radioiodinated clioquinol as a biomarker for beta-amyloid: Zn complexes in Alzheimer's disease

scientific article published in February 2006

Rapid decline in episodic memory in healthy older adults with high amyloid-β.

scientific article published in January 2013

Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta

scientific article

Rates of age- and amyloid β-associated cortical atrophy in older adults with superior memory performance

scientific article published on 12 August 2019

Rates of diagnostic transition and cognitive change at 18-month follow-up among 1,112 participants in the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing (AIBL).

scientific article

Reduced TRPC6 mRNA levels in the blood cells of patients with Alzheimer's disease and mild cognitive impairment

scientific article

Regional dynamics of amyloid-β deposition in healthy elderly, mild cognitive impairment and Alzheimer's disease: a voxelwise PiB-PET longitudinal study

scientific article published on 23 May 2012

Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease

scientific article

Regulation of prion gene expression by transcription factors SP1 and metal transcription factor-1.

scientific article

Relationship Between Amyloid-β Positivity and Progression to Mild Cognitive Impairment or Dementia over 8 Years in Cognitively Normal Older Adults

scientific article published on 01 January 2018

Relationship between Memory Performance and β-Amyloid Deposition at Different Stages of Alzheimer’s Disease ⬇️

scientific article published on January 1, 2012

Relationship between atrophy and beta-amyloid deposition in Alzheimer disease

scientific article published in March 2010

Relationship between physical activity, cognition, and Alzheimer pathology in autosomal dominant Alzheimer's disease

scientific article published on 25 September 2018

Relationships between performance on the Cogstate Brief Battery, neurodegeneration, and Aβ accumulation in cognitively normal older adults and adults with MCI.

scientific article published on 2 December 2014

Research and standardization in Alzheimer's trials: reaching international consensus

scientific article published on 23 December 2012

Restored degradation of the Alzheimer's amyloid-beta peptide by targeting amyloid formation

scientific article

SAGE analysis of genes differentially expressed in presymptomatic TgSOD1G93A transgenic mice identified cellular processes involved in early stage of ALS pathology

scientific article

Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial

scientific article published on 30 July 2008

Seizures as an early symptom of autosomal dominant Alzheimer's disease

scientific article published on 05 December 2018

Selecting cells with different Alzheimer's disease gamma-secretase activity using FACS. Differential effect on presenilin exon 9 gamma- and epsilon-cleavage

scientific article published in February 2003

Selective intracellular release of copper and zinc ions from bis(thiosemicarbazonato) complexes reduces levels of Alzheimer disease amyloid-beta peptide

scientific article

Selenium Levels in Serum, Red Blood Cells, and Cerebrospinal Fluid of Alzheimer's Disease Patients: A Report from the Australian Imaging, Biomarker & Lifestyle Flagship Study of Ageing (AIBL).

scientific article

Self and informant memory concerns align in healthy memory complainers and in early stages of mild cognitive impairment but separate with increasing cognitive impairment

scientific article published on 8 October 2015

Semi-automated hippocampal segmentation in people with cognitive impairment using an age appropriate template for registration

scientific article

Sensitivity of a Preclinical Alzheimer's Cognitive Composite (PACC) to amyloid β load in preclinical Alzheimer's disease

scientific article published on 29 March 2019

Sensitivity of composite scores to amyloid burden in preclinical Alzheimer's disease: Introducing the Z-scores of Attention, Verbal fluency, and Episodic memory for Nondemented older adults composite score

scientific article published on 12 December 2015

Sequence of Alzheimer disease biomarker changes in cognitively normal adults: A cross-sectional study

scientific article published on 01 September 2020

Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease

scientific article published on 21 January 2019

Serum neurofilament light chain levels are associated with white matter integrity in autosomal dominant Alzheimer's disease

scientific article published on 06 June 2020

Sex, amyloid, and APOE ε4 and risk of cognitive decline in preclinical Alzheimer's disease: Findings from three well-characterized cohorts

scientific article published on 24 May 2018

Single-subject grey matter network trajectories over the disease course of autosomal dominant Alzheimer's disease

scientific article published on 15 July 2020

Small Amphipathic Molecules Modulate Secondary Structure and Amyloid Fibril-forming Kinetics of Alzheimer Disease Peptide Aβ1–42 ⬇️

scientific article published on March 29, 2012

Small angle X-ray scattering analysis of Cu(2+)-induced oligomers of the Alzheimer's amyloid β peptide

scientific article published on March 2015

Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer's disease: a longitudinal study

scientific article published on 31 January 2018

Specific binding of the alzheimer βA4 amyloid precursor to collagen, laminin, and heparin

Spectrum of saccade system function in Alzheimer disease

scientific article

Stabilization of neurotoxic soluble beta-sheet-rich conformations of the Alzheimer's disease amyloid-beta peptide

scientific article

Stabilization of nontoxic Aβ-oligomers: insights into the mechanism of action of hydroxyquinolines in Alzheimer's disease

scientific article published in February 2015

Stereospecific interactions are necessary for Alzheimer disease amyloid-β toxicity

scientific article published on 25 March 2009

Stimulus pattern dependence of the Alzheimer's disease amyloid-beta 42 peptide's inhibition of long term potentiation in mouse hippocampal slices

scientific article published on 18 March 2009

Stronger effect of amyloid load than APOE genotype on cognitive decline in healthy older adults

scientific article published in October 2012

Structural studies of the Alzheimer's amyloid precursor protein copper-binding domain reveal how it binds copper ions

scientific article

Structural studies of the tethered N-terminus of the Alzheimer's disease amyloid-β peptide

scientific article

Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis

scientific article (publication date: 9 May 2003)

Subjective Memory Complaints in APOEɛ4 Carriers are Associated with High Amyloid-β Burden

scientific article published on 25 November 2015

Subjective memory decline predicts greater rates of clinical progression in preclinical Alzheimer's disease

scientific article published on 4 February 2016

Superior Memory Reduces 8-year Risk of Mild Cognitive Impairment and Dementia But Not Amyloid β-Associated Cognitive Decline in Older Adults

scientific article published on 01 July 2019

Supervised method to build an atlas database for multi-atlas segmentation-propagation

Surveillance for Creutzfeldt-Jakob disease in Australia: update to December 2012.

scientific article published on 30 June 2013

Surveillance of Creutzfeldt-Jakob disease in Australia: 2008.

scientific article published on June 2008

Surveillance of Creutzfeldt-Jakob disease in Australia: 2009 update.

scientific article published in June 2009

Surveillance of Creutzfeldt-Jakob disease in Australia: 2010 update

scientific article published on June 1, 2010

Surveillance of Creutzfeldt-Jakob disease in Australia: update to December 2010

scientific article published on June 1, 2011

Surveillance of Creutzfeldt-Jakob disease in Australia: update to December 2011.

scientific article published on 30 June 2012

Symptom onset in autosomal dominant Alzheimer disease: a systematic review and meta-analysis

scientific article

Tau imaging: early progress and future directions

scientific article

Tau protein: relevance to Parkinson's disease

scientific article

The APOE ε4 Allele Is Associated with Lower Selenium Levels in the Brain: Implications for Alzheimer's Disease

scientific article published on 28 April 2017

The ART of loss: Abeta imaging in the evaluation of Alzheimer's disease and other dementias

scientific article published on 09 August 2008

The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers

scientific article published on July 2011

The Alzheimer's therapeutic PBT2 promotes amyloid-β degradation and GSK3 phosphorylation via a metal chaperone activity

scientific article

The Animal Models of Dementia and Alzheimer’s Disease for Pre-Clinical Testing and Clinical Translation ⬇️

scientific article published on November 1, 2012

The Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging: methodology and baseline characteristics of 1112 individuals recruited for a longitudinal study of Alzheimer's disease

scientific article

The Aβcentric Pathway of Alzheimer’s Disease

article

The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease

scientific article published on 21 March 2019

The Brain Chart of Aging: Machine-learning analytics reveals links between brain aging, white matter disease, amyloid burden, and cognition in the iSTAGING consortium of 10,216 harmonized MR scans

scientific article published on 13 September 2020

The Caenorhabditis elegans A beta 1-42 model of Alzheimer disease predominantly expresses A beta 3-42.

scientific article

The Neurobiology and Age-Related Prevalence of the ε4 Allele of Apolipoprotein E in Alzheimer's Disease Cohorts

scientific article

The Prion Protein Preference of Sporadic Creutzfeldt-Jakob Disease Subtypes ⬇️

scientific article published on August 28, 2012

The Relationship between Sleep Quality and Brain Amyloid Burden

scientific article published on 12 April 2016

The Women's Healthy Ageing Project: fertile ground for investigation of healthy participants 'at risk' for dementia

scientific article published on December 2013

The amyloid precursor protein (APP) of Alzheimer disease and its paralog, APLP2, modulate the Cu/Zn-Nitric Oxide-catalyzed degradation of glypican-1 heparan sulfate in vivo

scientific article

The association of Aβ amyloid and composite cognitive measures in healthy older adults and MCI.

scientific article published on 18 July 2013

The dawn of robust individualised risk models for dementia

scientific article published on 13 September 2019

The effect of paraformaldehyde fixation and sucrose cryoprotection on metal concentration in murine neurological tissue

article

The hypoxia imaging agent CuII(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease

scientific article published on 2 April 2012

The intramembrane cleavage site of the amyloid precursor protein depends on the length of its transmembrane domain

scientific article

The neuroprotective domains of the amyloid precursor protein, in traumatic brain injury, are located in the two growth factor domains

scientific article published on 6 January 2011

The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson's disease

scientific article

The pattern of atrophy in familial Alzheimer disease: volumetric MRI results from the DIAN study

scientific article published on 18 September 2013

The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: modulation of APLP-1 processing by n-glycosylation

scientific article (publication date: 30 April 2004)

The role of metallobiology and amyloid-β peptides in Alzheimer's disease

scientific article

The structure of the amyloid-beta peptide high-affinity copper II binding site in Alzheimer disease

scientific article published on 3 July 2008

The transmembrane domain of the amyloid precursor protein in microsomal membranes is on both sides shorter than predicted

scientific article published on 25 November 2002

Therapeutic interventions ameliorating prion disease

scientific article published on February 2009

Three-month stability of the CogState brief battery in healthy older adults, mild cognitive impairment, and Alzheimer's disease: results from the Australian Imaging, Biomarkers, and Lifestyle-rate of change substudy (AIBL-ROCS).

scientific article

To What Extent Does Age at Death Account for Sex Differences in Rates of Mortality From Alzheimer Disease?

scientific article published on 01 July 2019

Toxicity of substrate-bound amyloid peptides on vascular smooth muscle cells is enhanced by homocysteine

scientific article

Trajectories of depressive and anxiety symptoms in older adults: a 6-year prospective cohort study.

scientific article

Trajectories of irregular word reading ability as a proxy for premorbid intelligence in Alzheimer’s disease, mild cognitive impairment, and healthy aging: A longitudinal study

scientific article published in October 2018

Transition-state analogue gamma-secretase inhibitors stabilize a 900 kDa presenilin/nicastrin complex.

scientific article

Transmissible spongiform encephalopathies.

scientific article

Traumatic brain injury induces elevation of Co in the human brain

scientific article published on 26 November 2014

Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease beta-amyloid

scientific article

Use of an experimental language acquisition paradigm for standardized neuropsychological assessment of learning: A pilot study in young and older adults

scientific article published on 13 September 2019

Use of the CogState Brief Battery in the assessment of Alzheimer's disease related cognitive impairment in the Australian Imaging, Biomarkers and Lifestyle (AIBL) study

scientific article published on 17 January 2012

Using Robust Normative Data to Investigate the Neuropsychology of Cognitive Aging

scientific article

Using subjective cognitive decline to identify high global amyloid in community-based samples: A cross-cohort study

scientific article published on 25 September 2019

Utility of an Alzheimer's Disease Risk-Weighted Polygenic Risk Score for Predicting Rates of Cognitive Decline in Preclinical Alzheimer's Disease: A Prospective Longitudinal Study

scientific article published on 01 January 2018

Utility of an improved model of amyloid-beta (Aβ₁₋₄₂) toxicity in Caenorhabditis elegans for drug screening for Alzheimer's disease

scientific article

Validation of a priori candidate Alzheimer's disease SNPs with brain amyloid-beta deposition

scientific article published on 19 November 2019

Variability in Blood-Based Amyloid-β Assays: The Need for Consensus on Pre-Analytical Processing ⬇️

scientific article published on January 1, 2012

Visual assessment versus quantitative assessment of 11C-PIB PET and 18F-FDG PET for detection of Alzheimer's disease

scientific article published in April 2007

Visual paired associate learning deficits associated with elevated beta-amyloid in cognitively normal older adults

scientific article published on 01 August 2019

White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer's disease

article by Miguel Ángel Araque Caballero et al published 1 October 2018 in Brain

White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer's disease

scientific article published on 9 May 2018

White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network

scientific article

Zinc induces depletion and aggregation of endogenous TDP-43.

scientific article

beta-Amyloid as a molecular therapeutic target in Alzheimer's disease

scientific article published on April 2009

sAPPα rescues deficits in amyloid precursor protein knockout mice following focal traumatic brain injury

scientific article published on 17 May 2012

val158met is not associated with Aβ-amyloid and ε4 related cognitive decline in cognitively normal older adults ⬇️

scientific article published on 02 May 2019

β-Amyloid, APOE and BDNF Genotype, and Depressive and Anxiety Symptoms in Cognitively Normal Older Women and Men.

scientific article published on 17 August 2016

β-amyloid in biological samples: not all Aβ detection methods are created equal

scientific article

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