Search filters

List of works by Berta Strulovici

A 1,536-well [(35)S]GTPgammaS scintillation proximity binding assay for ultra-high-throughput screening of an orphan galphai-coupled GPCR.

scientific article published in June 2008

A 1,536-well ultra-high-throughput siRNA screen to identify regulators of the Wnt/beta-catenin pathway

scientific article

A 1536-well cAMP assay for Gs- and Gi-coupled receptors using enzyme fragmentation complementation.

scientific article published in February 2004

A beta-lactamase-dependent Gal4-estrogen receptor beta transactivation assay for the ultra-high throughput screening of estrogen receptor beta agonists in a 3456-well format

scientific article published on December 2003

A cell-based beta-lactamase reporter gene assay for the identification of inhibitors of hepatitis C virus replication

scientific article

A cell-based ultra-high-throughput screening assay for identifying inhibitors of D-amino acid oxidase

scientific article

A collaborative screening program for the discovery of inhibitors of HCV NS2/3 cis-cleaving protease activity

scientific article published in April 2002

A fluorescence-based thiol quantification assay for ultra-high-throughput screening for inhibitors of coenzyme A production

scientific article published in June 2008

A fully automated [35S]GTPgammaS scintillation proximity assay for the high-throughput screening of Gi-linked G protein-coupled receptors

scientific article published in April 2003

A high-precision fluorogenic cholesteryl ester transfer protein assay compatible with animal serum and 3456-well assay technology

scientific article published on 8 June 2007

A miniaturized cell-based fluorescence resonance energy transfer assay for insulin-receptor activation

scientific article published on 9 June 2006

A multiplexed siRNA screening strategy to identify genes in the PARP pathway

scientific article published on 10 July 2012

A rational utilization of high-throughput screening affords selective, orally bioavailable 1-benzyl-3-carboxyazetidine sphingosine-1-phosphate-1 receptor agonists

scientific article

A short-incubation reporter-gene assay for high-throughput screening of estrogen receptor-alpha antagonists

scientific article published in August 2005

An efficient and fully automated high-throughput transfection method for genome-scale siRNA screens

scientific article

Application of division arrest technology to cell-based HTS: comparison with frozen and fresh cells

scientific article

Application of real-time cell electronic sensing (RT-CES) technology to cell-based assays

scientific article published on August 2004

Compounds that bind APP and inhibit Abeta processing in vitro suggest a novel approach to Alzheimer disease therapeutics

scientific article (publication date: 6 May 2005)

Current trends in high-throughput screening

scientific article published on August 2008

Development of an intact cell reporter gene beta-lactamase assay for G protein-coupled receptors for high-throughput screening

scientific article published on March 2003

Development of an oxazolopyridine series of dual thrombin/factor Xa inhibitors via structure-guided lead optimization

scientific article published in October 2005

Genome-scale RNAi screen for host factors required for HIV replication

scientific article published on 30 October 2008

High-throughput cell-based screening using scintillation proximity assay for the discovery of inositol phosphatase inhibitors.

scientific article published in March 2004

High-throughput screening of 11beta-hydroxysteroid dehydrogenase type 1 in scintillation proximity assay format

scientific article published in August 2005

Hit selection with false discovery rate control in genome-scale RNAi screens

scientific article

Identification of metabotropic glutamate receptor antagonists using an automated high-throughput screening system

scientific article published on February 2003

Identification of small molecule antagonists of the human mas-related gene-X1 receptor

scientific article published on 3 February 2006

Identification of small-molecule modulators of mouse SVZ progenitor cell proliferation and differentiation through high-throughput screening

scientific article

Induced pluripotent stem cells — opportunities for disease modelling and drug discovery

scientific article published on November 11, 2011

Integrating experimental and analytic approaches to improve data quality in genome-wide RNAi screens

scientific article

LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease

scientific article

Median absolute deviation to improve hit selection for genome-scale RNAi screens

scientific article

Miniaturizable homogenous time-resolved fluorescence assay for carboxypeptidase B activity

scientific article published on June 1, 2003

Miniaturization and HTS of a FRET-based membrane potential assay for K(ir) channel inhibitors

scientific article

Miniaturization and automation of an ubiquitin ligase cascade enzyme-linked immunosorbent assay in 1,536-well format

scientific article published in August 2007

Miniaturization of absorbance assays using the fluorescent properties of white microplates

scientific article

Miniaturization of intracellular calcium functional assays to 1536-well plate format using a fluorometric imaging plate reader

scientific article

Miniaturization of whole live cell-based GPCR assays using microdispensing and detection systems

scientific article

Small interfering RNA screens reveal enhanced cisplatin cytotoxicity in tumor cells having both BRCA network and TP53 disruptions

scientific article

The use of strictly standardized mean difference for hit selection in primary RNA interference high-throughput screening experiments

scientific article published on 13 April 2007

Ultra-high-throughput screening for antagonists of a Gi-coupled receptor in a 2.2-microl 3,456-well plate format cyclicAMP assay

scientific article