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List of works by Heli Skottman

A defined and xeno-free culture method enabling the establishment of clinical-grade human embryonic, induced pluripotent and adipose stem cells

scientific article

A xeno-free culturing protocol for pluripotent stem cell-derived oligodendrocyte precursor cell production

scientific article published on July 2011

An antibody surface for selective neuronal cell attachment

scientific article published on 10 November 2009

Aquaporin expression and function in human pluripotent stem cell-derived retinal pigmented epithelial cells.

scientific article published on May 2013

Autophagy Regulates Proteasome Inhibitor-Induced Pigmentation in Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells

scientific article

Avoiding the Pitfalls of siRNA Delivery to the Retinal Pigment Epithelium with Physiologically Relevant Cell Models

scientific article published on 16 July 2020

Biomimetic collagen I and IV double layer Langmuir-Schaefer films as microenvironment for human pluripotent stem cell derived retinal pigment epithelial cells

scientific article published on 20 February 2015

Breath figures in tissue engineering and drug delivery: State-of-the-art and future perspectives

scientific article published on 25 November 2017

CACNB2 Is a Novel Susceptibility Gene for Diabetic Retinopathy in Type 1 Diabetes

scientific article published on 22 August 2019

CD marker expression profiles of human embryonic stem cells and their neural derivatives, determined using flow-cytometric analysis, reveal a novel CD marker for exclusion of pluripotent stem cells.

scientific article published on 16 September 2008

Challenges and approaches to the culture of pluripotent human embryonic stem cells

scientific article published on May 2007

Co-culture of human induced pluripotent stem cell-derived retinal pigment epithelial cells and endothelial cells on double collagen-coated honeycomb films

scientific article published on 08 November 2019

Collagen-immobilized polyimide membranes for retinal pigment epithelial cell adherence and proliferation

Comparative analysis of targeted differentiation of human induced pluripotent stem cells (hiPSCs) and human embryonic stem cells reveals variability associated with incomplete transgene silencing in retrovirally derived hiPSC lines

scientific article published on 22 January 2013

Comparative proteomic analysis of human embryonic stem cell-derived and primary human retinal pigment epithelium.

scientific article

Comparative proteomics reveals human pluripotent stem cell-derived limbal epithelial stem cells are similar to native ocular surface epithelial cells.

scientific article

Comparison of biomaterials and extracellular matrices as a culture platform for multiple, independently derived human embryonic stem cell lines.

scientific article

Compromised Barrier Function in Human Induced Pluripotent Stem-Cell-Derived Retinal Pigment Epithelial Cells from Type 2 Diabetic Patients

scientific article published on 01 August 2019

Computational Model of Ca2+ Wave Propagation in Human Retinal Pigment Epithelial ARPE-19 Cells

scientific article

Corneal epithelial differentiation of human pluripotent stem cells generates ABCB5 and ∆Np63α cells with limbal cell characteristics and high wound healing capacity

Culture conditions for human embryonic stem cells

scientific article published on November 2006

Derivation and characterization of three new human embryonic stem cell lines in Finland

scientific article

Derivation of human embryonic stem cell lines in serum replacement medium using postnatal human fibroblasts as feeder cells.

scientific article

Differential Expression of Inflammasome-Related Genes in Induced Pluripotent Stem-Cell-Derived Retinal Pigment Epithelial Cells with or without History of Age-Related Macular Degeneration

scientific article published in 2021

Distinct sets of developmentally regulated genes that are expressed by human oocytes and human embryonic stem cells

scientific article published on 27 November 2006

Drug Flux Across RPE Cell Models: The Hunt for An Appropriate Outer Blood-Retinal Barrier Model for Use in Early Drug Discovery

scientific article published on 19 February 2020

Effects of Cytokine Activation and Oxidative Stress on the Function of the Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells.

scientific article

Effects of different serum conditions on osteogenic differentiation of human adipose stem cells in vitro.

scientific article published on 15 February 2013

Efficient and Scalable Directed Differentiation of Clinically Compatible Corneal Limbal Epithelial Stem Cells from Human Pluripotent Stem Cells

scientific article published on 24 October 2018

Efflux protein expression in human stem cell-derived retinal pigment epithelial cells

scientific article

Electric impedance of human embryonic stem cell-derived retinal pigment epithelium ⬇️

scientific article published on December 22, 2011

Exclusion of coding-region mutations in luteinizing hormone and follicle-stimulating hormone receptor genes as the cause of ovarian hyperstimulation syndrome

article

Expression of leukemia inhibitory factor and its receptors is increased during differentiation of human embryonic stem cells.

scientific article

Feeder-free derivation of human embryonic stem-cell lines

scientific article

Functional Voltage-Gated Calcium Channels Are Present in Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium

scientific article published on 04 November 2018

Gene expression signatures of seven individual human embryonic stem cell lines

scientific article

Generation of hESC-derived retinal pigment epithelium on biopolymer coated polyimide membranes

scientific article published on 11 August 2012

Good manufacturing practice and clinical-grade human embryonic stem cell lines

scientific article published on April 2008

Healthy human CSF promotes glial differentiation of hESC-derived neural cells while retaining spontaneous activity in existing neuronal networks.

scientific article published on 13 May 2013

Honeycomb porous films as permeable scaffold materials for human embryonic stem cell-derived retinal pigment epithelium.

scientific article published on 23 February 2016

Hsp90 inhibition as a means to inhibit activation of the NLRP3 inflammasome.

scientific article published on 30 April 2018

Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium-Role in Dead Cell Clearance and Inflammation

scientific article published on 20 February 2019

Human cell-based micro electrode array platform for studying neurotoxicity ⬇️

scientific article published on September 30, 2010

Human embryonic stem cell-derived cardiomyocytes: demonstration of a portion of cardiac cells with fairly mature electrical phenotype

scientific article published on 01 April 2010

Human embryonic stem cell-derived neuronal cells form spontaneously active neuronal networks in vitro.

scientific article published on 22 April 2009

Human embryonic stem cells are immunogenic in allogeneic and xenogeneic settings

scientific article published on 01 November 2006

Human iPSC derived disease model of MERTK-associated retinitis pigmentosa

scientific article

Human pluripotent stem cell-derived limbal epithelial stem cells on bioengineered matrices for corneal reconstruction.

scientific article published on 30 November 2015

Human stem cell based corneal tissue mimicking structures using laser-assisted 3D bioprinting and functional bioinks.

scientific article published on 16 April 2018

Hydrazone crosslinked hyaluronan-based hydrogels for therapeutic delivery of adipose stem cells to treat corneal defects.

scientific article

In Vitro Cultivation of Limbal Epithelial Stem Cells on Surface-Modified Crosslinked Collagen Scaffolds

scientific article published on 01 April 2019

In vitro stem cell modelling demonstrates a proof-of-concept for excess functional mutant TIMP3 as the cause of Sorsby Fundus Dystrophy

scientific article published on 15 July 2020

Integrating probe-level expression changes across generations of Affymetrix arrays

scientific article

Laminin-511 expression is associated with the functionality of feeder cells in human embryonic stem cell culture

scientific article published on 27 August 2011

Langmuir-Schaefer film deposition onto honeycomb porous films for retinal tissue engineering

scientific article published on 18 February 2017

Limbal Stem Cells on Bacterial Nanocellulose Carriers for Ocular Surface Regeneration

scientific article

Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration

article

Modulation of Wnt/BMP pathways during corneal differentiation of hPSC maintains ABCG2-positive LSC population that demonstrates increased regenerative potential

scientific article published on 05 August 2019

Monitoring and analysis of dynamic growth of human embryonic stem cells: comparison of automated instrumentation and conventional culturing methods

scientific article published on 12 April 2007

Ormocomp-modified glass increases collagen binding and promotes the adherence and maturation of human embryonic stem cell-derived retinal pigment epithelial cells

scientific article

Patient-Specific Induced Pluripotent Stem Cell-Derived RPE Cells: Understanding the Pathogenesis of Retinopathy in Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency

scientific article published on May 2015

Poly(trimethylene carbonate) as an elastic biodegradable film for human embryonic stem cell-derived retinal pigment epithelial cells

scientific article published on 4 January 2017

Production and isolation of NG2+ oligodendrocyte precursors from human embryonic stem cells in defined serum-free medium

scientific article published on 9 June 2010

Quantitative pigment extraction analysis for human pluripotent stem cell derived retinal pigment epithelial cells

RNA Polymerase III Subunit POLR3G Regulates Specific Subsets of PolyA+ and SmallRNA Transcriptomes and Splicing in Human Pluripotent Stem Cells

scientific article published on May 2017

Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage

scientific article

Semi-automatic Method for Ca2+ Imaging Data Analysis of Maturing Human Embryonic Stem Cells-Derived Retinal Pigment Epithelium.

scientific article

Similarly derived and cultured hESC lines show variation in their developmental potential towards neuronal cells in long-term culture

scientific article published in September 2010

Small non-coding RNA landscape of extracellular vesicles from human stem cells

scientific article published in Scientific Reports

Small-molecule induction promotes corneal epithelial cell differentiation from human induced pluripotent stem cells

scientific article published on 06 February 2014

Sodium channels enable fast electrical signaling and regulate phagocytosis in the retinal pigment epithelium

scientific article published on 15 August 2019

Spatial and temporal expression pattern of germ layer markers during human embryonic stem cell differentiation in embryoid bodies

scientific article published on 6 April 2010

Structure and barrier properties of human embryonic stem cell-derived retinal pigment epithelial cells are affected by extracellular matrix protein coating

scientific article published on 20 January 2014

Structured PDMS Chambers for Enhanced Human Neuronal Cell Activity on MEA Platforms

Substantial variation in the cardiac differentiation of human embryonic stem cell lines derived and propagated under the same conditions--a comparison of multiple cell lines.

scientific article

Surface Modified Biodegradable Electrospun Membranes as a Carrier for Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells

scientific article

Survival and functionality of xeno-free human embryonic stem cell-derived retinal pigment epithelial cells on polyester substrate after transplantation in rabbits

scientific article published on 28 December 2018

Testing of nine different xeno-free culture media for human embryonic stem cell cultures

scientific article published on 24 January 2007

Texture Descriptors Ensembles Enable Image-Based Classification of Maturation of Human Stem Cell-Derived Retinal Pigmented Epithelium

scientific article published on 19 February 2016

The derivation of clinical-grade human embryonic stem cell lines

scientific article

The effect of human and mouse fibroblast feeder cells on cardiac differentiation of human pluripotent stem cells

scientific article published on 19 January 2012

Three-dimensional growth matrix for human embryonic stem cell-derived neuronal cells ⬇️

scientific article published on May 18, 2012

Tissue adhesive hyaluronic acid hydrogels for sutureless stem cell delivery and regeneration of corneal epithelium and stroma

scientific article published on 23 September 2019

Toward the defined and xeno-free differentiation of functional human pluripotent stem cell-derived retinal pigment epithelial cells.

scientific article

Towards a defined, serum- and feeder-free culture of stratified human oral mucosal epithelium for ocular surface reconstruction ⬇️

scientific article published on September 11, 2012

Transcriptome profiling of human pre-implantation development

scientific article

Ultrathin Polyimide Membrane as Cell Carrier for Subretinal Transplantation of Human Embryonic Stem Cell Derived Retinal Pigment Epithelium

scientific article published on 25 November 2015

Unique gene expression signature by human embryonic stem cells cultured under serum-free conditions correlates with their enhanced and prolonged growth in an undifferentiated stage

scientific article published on 11 August 2005

Wound healing of human embryonic stem cell-derived retinal pigment epithelial cells is affected by maturation stage

scientific article published on 31 July 2018

Xeno- and feeder-free differentiation of human pluripotent stem cells to two distinct ocular epithelial cell types using simple modifications of one method

scientific article published on 29 December 2017

[Stem cell therapy of the eye]

scientific article published on 01 January 2014

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