Advanced search

Authors whose works are in public domain in at least one jurisdiction

List of works by Toshihisa Ishikawa

A CASE OF SUMMER-TYPE HYPERSENSITIVITY PNEUMONITIS ACCOMPANIED BY THE SYNDROME OF INAPPROPRIATE SECRETION OF ANTIDIURETIC HORMONE

scientific article published in January 2018

A SNP in the ABCC11 gene is the determinant of human earwax type

scientific article

A new strategy of high-speed screening and quantitative structure-activity relationship analysis to evaluate human ATP-binding cassette transporter ABCG2-drug interactions

scientific article published on 17 February 2006

ABCC11/MRP8 polymorphisms affect 5-fluorouracil-induced severe toxicity and hepatic expression.

scientific article published in September 2013

ABCC13, an unusual truncated ABC transporter, is highly expressed in fetal human liver

scientific article

Are human ATP-binding cassette transporter C11 and earwax associated with the incidence of cholesteatoma?

scientific article published on 24 February 2018

Association between breast cancer risk and the wild-type allele of human ABC transporter ABCC11

scientific article published on 01 December 2010

Association of cumulative cyclosporine dose with its irreversible nephrotoxicity in Japanese patients with pediatric-onset autoimmune diseases

scientific article published on 01 December 2007

Cellular phototoxicity evoked through the inhibition of human ABC transporter ABCG2 by cyclin-dependent kinase inhibitors in vitro

scientific article published on 9 October 2008

Characterization of the mouse Abcc12 gene and its transcript encoding an ATP-binding cassette transporter, an orthologue of human ABCC12.

scientific article published on May 2003

Clinical SNP Detection by the SmartAmp Method ⬇️

scientific article published on January 1, 2013

Clinical and Molecular Evidence of ABCC11 Protein Expression in Axillary Apocrine Glands of Patients with Axillary Osmidrosis

scientific article published on 15 February 2017

Critical role of ABCG2 in ALA-photodynamic diagnosis and therapy of human brain tumor

scientific article

Diagnosis of Human Axillary Osmidrosis by Genotyping of the Human ABCC11 Gene: Clinical Practice and Basic Scientific Evidence

scientific article

Direct genotyping of Cytochrome P450 2A6 whole gene deletion from human blood samples by the SmartAmp method ⬇️

scientific article published on March 21, 2011

Disruption of N-linked glycosylation enhances ubiquitin-mediated proteasomal degradation of the human ATP-binding cassette transporter ABCG2

scientific article

Does ABCG2 need a heterodimer partner? Expression and functional evaluation of ABCG2 (Arg 482)*.

scientific article published in January 2002

Drug-induced phototoxicity evoked by inhibition of human ABC transporter ABCG2: development of in vitro high-speed screening systems

scientific article published on 01 March 2008

Earwax, osmidrosis, and breast cancer: why does one SNP (538G>A) in the human ABC transporter ABCC11 gene determine earwax type?

scientific article

Emerging new technologies in Pharmacogenomics: rapid SNP detection, molecular dynamic simulation, and QSAR analysis methods to validate clinically important genetic variants of human ABC Transporter ABCB1 (P-gp/MDR1).

scientific article published on 04 February 2010

Emerging new technology: QSAR analysis and MO Calculation to characterize interactions of protein kinase inhibitors with the human ABC transporter, ABCG2 (BCRP).

scientific article published on January 2010

Evaluation of human P-glycoprotein (MDR1/ABCB1) ATPase activity assay method by comparing with in vitro transport measurements: Michaelis-Menten kinetic analysis to estimate the affinity of P-glycoprotein to drugs

scientific article published on December 2006

Expression and functional characterization of human ABC transporter ABCG2 variants in insect cells

scientific article published in January 2003

FAMILIAL SUMMER-TYPE HYPERSENSITIVITY PNEUMONITIS INDUCED IN SUMMER AND WINTER AT THE WORK PLACE

scientific article published in January 2017

Functional evaluation of ABCB1 (P-glycoprotein) polymorphisms: high-speed screening and structure-activity relationship analyses

scientific article published in February 2004

Functional validation of the genetic polymorphisms of human ATP-binding cassette (ABC) transporter ABCG2: identification of alleles that are defective in porphyrin transport.

scientific article published on 11 April 2006

Gefitinib enhances the antitumor activity of CPT-11 in vitro and in vivo by inhibiting ABCG2 but not ABCB1: a new clue to circumvent gastrointestinal toxicity risk

scientific article published on January 2013

Gefitinib enhances the efficacy of photodynamic therapy using 5-aminolevulinic acid in malignant brain tumor cells ⬇️

scientific article published on July 20, 2012

Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCG2: therapeutic implications

scientific article

Genetic polymorphisms of human ABC transporter ABCG2: development of the standard method for functional validation of SNPs by using the Flp recombinase system

scientific article published in January 2006

High-speed screening and QSAR analysis of human ATP-binding cassette transporter ABCB11 (bile salt export pump) to predict drug-induced intrahepatic cholestasis

scientific article published on May 2006

High-speed screening of human ATP-binding cassette transporter function and genetic polymorphisms: new strategies in pharmacogenomics.

scientific article published in January 2005

Human ABC transporter ABCG2 in cancer chemotherapy and pharmacogenomics

scientific article published on January 2009

Human ABC transporter ABCG2 in cancer chemotherapy: drug molecular design to circumvent multidrug resistance

scientific article published in January 2012

Human ABC transporter ABCG2 in xenobiotic protection and redox biology

scientific article published on January 2006

Identification of two biologically crucial hydroxyl groups of (-)-epigallocatechin gallate in osteoclast culture

scientific article published on 12 September 2006

In vitro evaluation of photosensitivity risk related to genetic polymorphisms of human ABC transporter ABCG2 and inhibition by drugs

scientific article published on December 2007

Intramolecular disulfide bond is a critical check point determining degradative fates of ATP-binding cassette (ABC) transporter ABCG2 protein

scientific article published on 8 August 2007

Major SNP (Q141K) variant of human ABC transporter ABCG2 undergoes lysosomal and proteasomal degradations

scientific article

Methods to Examine the Impact of Nonsynonymous SNPs on Protein Degradation and Function of Human ABC Transporter ⬇️

scientific article published on January 1, 2013

Molecular and cytogenetic characterization of the mouse ATP-binding cassette transporter Abcg4.

scientific article

Molecular modeling of new camptothecin analogues to circumvent ABCG2-mediated drug resistance in cancer

scientific article

Mutation analysis of 2009 pandemic influenza A(H1N1) viruses collected in Japan during the peak phase of the pandemic

scientific article

Nitensidine A, a guanidine alkaloid from Pterogyne nitens, is a novel substrate for human ABC transporter ABCB1.

scientific article published on 14 October 2013

Novel camptothecin analogues that circumvent ABCG2-associated drug resistance in human tumor cells.

scientific article published on July 2004

Nrf2-dependent and -independent induction of ABC transporters ABCC1, ABCC2, and ABCG2 in HepG2 cells under oxidative stress

scientific article published on January 2007

Nrf2-dependent induction of human ABC transporter ABCG2 and heme oxygenase-1 in HepG2 cells by photoactivation of porphyrins: biochemical implications for cancer cell response to photodynamic therapy

scientific article published on January 2008

Nuclear receptor-mediated transcriptional regulation in Phase I, II, and III xenobiotic metabolizing systems

scientific article published on December 2006

One-step detection of the 2009 pandemic influenza A(H1N1) virus by the RT-SmartAmp assay and its clinical validation

scientific article

Pharmacogenetics of human ABC transporter ABCC11: new insights into apocrine gland growth and metabolite secretion

scientific article published in 2012

Pharmacogenomics of Human ABC Transporter ABCC11 (MRP8): Potential Risk of Breast Cancer and Chemotherapy Failure ⬇️

scientific article published on October 1, 2010

Pharmacogenomics of Human ABC Transporters: Detection of Clinically Important SNPs by SmartAmp2 Method ⬇️

scientific article published on April 1, 2011

Pharmacogenomics of drug transporters: a new approach to functional analysis of the genetic polymorphisms of ABCB1 (P-glycoprotein/MDR1).

scientific article

Pharmacogenomics of the human ABC transporter ABCG2: from functional evaluation to drug molecular design

scientific article published in October 2005

Pivotal roles of peptide transporter PEPT1 and ATP-binding cassette (ABC) transporter ABCG2 in 5-aminolevulinic acid (ALA)-based photocytotoxicity of gastric cancer cells in vitro ⬇️

scientific article published on January 4, 2012

Prediction of drug-induced intrahepatic cholestasis: in vitro screening and QSAR analysis of drugs inhibiting the human bile salt export pump

scientific article published on January 2007

Production of cells with targeted integration of gene variants of human ABC transporter for stable and regulated expression using the Flp recombinase system

scientific article published on January 2010

Prognostic potential of the MDM2 309T>G polymorphism in stage I lung adenocarcinoma

scientific article published on 26 May 2016

Quality control of human ABCG2 protein in the endoplasmic reticulum: ubiquitination and proteasomal degradation

scientific article published on 11 December 2008

Quantitative structure--activity relationship analysis and molecular dynamics simulation to functionally validate nonsynonymous polymorphisms of human ABC transporter ABCB1 (P-glycoprotein/MDR1).

scientific article published on 9 June 2007

Rapid Detection of SNP (c.309T>G) in the MDM2 Gene by the Duplex SmartAmp Method ⬇️

scientific article published on April 2, 2013

Rapid and cost-effective SNP detection method: application of SmartAmp2 to pharmacogenomics research

scientific article published in July 2009

Re-evaluation and functional classification of non-synonymous single nucleotide polymorphisms of the human ATP-binding cassette transporter ABCG2.

scientific article published on February 2007

Regulation of the Axillary Osmidrosis-Associated ABCC11 Protein Stability by N-Linked Glycosylation: Effect of Glucose Condition

scientific article

Role of Nrf2 in Cancer Photodynamic Therapy: Regulation of Human ABC Transporter ABCG2 ⬇️

scientific article published on 06 May 2013

SNP (–617C>A) in ARE-Like Loci of the NRF2 Gene: A New Biomarker for Prognosis of Lung Adenocarcinoma in Japanese Non-Smoking Women ⬇️

scientific article published on September 11, 2013

Simple non-ion-paired high-performance liquid chromatographic method for simultaneous quantitation of carboxylate and lactone forms of 14 new camptothecin derivatives

scientific article published in September 2003

Single-nucleotide polymorphism (c.309T>G) in the MDM2 gene and lung cancer risk

scientific article

Synthesis and evaluation of 3D templates based on a taxane skeleton to circumvent P-glycoprotein-associated multidrug resistance of cancer

scientific article published in May 2005

Technical pitfalls and improvements for high-speed screening and QSAR analysis to predict inhibitors of the human bile salt export pump (ABCB11/BSEP).

scientific article published on 18 August 2009

The SmartAmp method: rapid detection of SNPs in thiopurine S-methyltransferase and ABC transporters ABCC4 and ABCG2

scientific article published on 01 September 2012

The genetic polymorphism of drug transporters: functional analysis approaches.

scientific article published on January 2004

Transport mechanism-based drug molecular design: novel camptothecin analogues to circumvent ABCG2-associated drug resistance of human tumor cells

scientific article

Transport of SN-38 by the wild type of human ABC transporter ABCG2 and its inhibition by quercetin, a natural flavonoid.

scientific article published in April 2004

Transport-metabolism interplay: LXRalpha-mediated induction of human ABC transporter ABCC2 (cMOAT/MRP2) in HepG2 cells

scientific article

Transporter-Mediated Drug Interaction Strategy for 5-Aminolevulinic Acid (ALA)-Based Photodynamic Diagnosis of Malignant Brain Tumor: Molecular Design of ABCG2 Inhibitors ⬇️

scientific article published on September 14, 2011

Ubiquitin-Mediated Proteasomal Degradation of ABC Transporters: a New Aspect of Genetic Polymorphisms and Clinical Impacts ⬇️

scientific article published on May 12, 2011

Ubiquitin-mediated proteasomal degradation of non-synonymous SNP variants of human ABC transporter ABCG2.

scientific article published on May 2008

[Drug resistance mediated by ABC transporters]

scientific article published on 01 January 2004

[Genetic polymorphisms of human ABC transporter ABCG2: Porphyria risk and ER quality control]

scientific article published on 01 February 2007

[Role of ABC transporters in porphyrin biosynthesis and heme metabolism]

scientific article published on 01 October 2007

[The pharmacogenomics of drug transporters: functional analysis approaches]

scientific article published on 01 September 2004

[To promise personalized medicine: development of world's fastest SNP detection method to circumvent drug-induced adverse reactions]

scientific article published on 01 February 2010

Paulina is supported by:

About Paulina

Help