Search filters

List of works by Mamoru Hasegawa

A free radical scavenger but not FGF-2-mediated angiogenic therapy rescues myonephropathic metabolic syndrome in severe hindlimb ischemia

scientific article

A novel protective MHC-I haplotype not associated with dominant Gag-specific CD8+ T-cell responses in SIVmac239 infection of Burmese rhesus macaques

scientific article

Abrogation of AIDS vaccine-induced cytotoxic T-lymphocyte efficacy in vivo due to a change in viral epitope flanking sequences

scientific article published on 8 December 2007

Acute toxicity study of a simian immunodeficiency virus-based lentiviral vector for retinal gene transfer in nonhuman primates

scientific article published on September 2009

An improved method for recovery of F-defective Sendai virus expressing foreign genes from cloned cDNA.

scientific article published on July 2002

Angiogenic gene therapy for experimental critical limb ischemia: acceleration of limb loss by overexpression of vascular endothelial growth factor 165 but not of fibroblast growth factor-2.

scientific article

Antagonism of VEGF by Genetically Engineered Dendritic Cells Is Essential to Induce Antitumor Immunity against Malignant Ascites ⬇️

scientific article published on January 5, 2011

Antigen-specific T-cell induction by vaccination with a recombinant Sendai virus vector even in the presence of vector-specific neutralizing antibodies in rhesus macaques

scientific article published on 6 May 2008

BioKnife, a uPA Activity-dependent Oncolytic Sendai Virus, Eliminates Pleural Spread of Malignant Mesothelioma via Simultaneous Stimulation of uPA Expression ⬇️

scientific article published on February 7, 2012

CFTR gene transfer to human cystic fibrosis pancreatic duct cells using a Sendai virus vector.

scientific article

Carbon-ion beam treatment induces systemic antitumor immunity against murine squamous cell carcinoma

scientific article published on August 2010

Collection and analysis of hematopoietic progenitor cells from cynomolgus macaques (Macaca fascicularis): assessment of cross-reacting monoclonal antibodies

scientific article

Comparison between Sendai virus and adenovirus vectors to transduce HIV-1 genes into human dendritic cells

scientific article published in March 2008

Comparison of sendai virus-mediated gene transfer efficiency to adhesive and floating adipose tissue-derived stem cells

scientific article published in January 2009

Comparison of the expression and immunogenicity of wild-type and sequence-modified HIV-1 gag genes in a recombinant Sendai virus vector

scientific article published in April 2010

Cytokine-based high log-scale expansion of functional human dendritic cells from cord-blood CD34-positive cells ⬇️

scientific article published on November 29, 2011

Cytokine-based log-scale expansion of functional murine dendritic cells

scientific article

Cytoplasmic RNA vector derived from nontransmissible Sendai virus. Production and use.

scientific article

Cytoplasmic expression and extracellular deposition of an antiangiogenic factor, pigment epithelium-derived factor, in human atherosclerotic plaques.

scientific article published on 30 June 2005

Cytotoxic T lymphocyte-based control of simian immunodeficiency virus replication in a preclinical AIDS vaccine trial

scientific article

DVC1-0101 to treat peripheral arterial disease: a Phase I/IIa open-label dose-escalation clinical trial

scientific article published on 15 January 2013

Development of immunostimulatory virotherapy using non-transmissible Sendai virus-activated dendritic cells

scientific article published on 2 February 2007

Diabetic microangiopathy in ischemic limb is a disease of disturbance of the platelet-derived growth factor-BB/protein kinase C axis but not of impaired expression of angiogenic factors

scientific article published on 23 November 2005

Differentiation of Mouse Pancreatic Stem Cells Into Insulin-Producing Cells by Recombinant Sendai Virus-Mediated Gene Transfer Technology

scientific article published on January 2012

Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors

scientific article

Efficient protective immunity against Trypanosoma cruzi infection after nasal vaccination with recombinant Sendai virus vector expressing amastigote surface protein-2.

scientific article published on 25 August 2009

Engraftment and tumor formation after allogeneic in utero transplantation of primate embryonic stem cells

scientific article

Essential role of PDGFRalpha-p70S6K signaling in mesenchymal cells during therapeutic and tumor angiogenesis in vivo: role of PDGFRalpha during angiogenesis

scientific article published in April 2004

Ex Vivo and In Vivo Lentivirus-Mediated Transduction of Airway Epithelial Progenitor Cells

scientific article

Ex vivo expansion of human HSCs with Sendai virus vector expressing HoxB4 assessed by sheep in utero transplantation

scientific article published on 26 September 2010

Fibroblast growth factor-2 determines severity of joint disease in adjuvant-induced arthritis in rats

scientific article published in January 2002

Fibroblast growth factor-2 gene transfer can stimulate hepatocyte growth factor expression irrespective of hypoxia-mediated downregulation in ischemic limbs

scientific article

Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells.

scientific article

High-level in vivo gene marking after gene-modified autologous hematopoietic stem cell transplantation without marrow conditioning in nonhuman primates

scientific article

Identification of pendrin as a common mediator for mucus production in bronchial asthma and chronic obstructive pulmonary disease

scientific article

Immunogenicity of repeated Sendai viral vector vaccination in macaques

scientific article published on 31 July 2012

Immunostimulatory virotherapy using recombinant Sendai virus as a new cancer therapeutic regimen

scientific article published on January 2008

Immunostimulatory virotherapy using recombinant Sendai virus as a new cancer therapeutic regimen

scientific article published on May 2008

In vivo expansion of gene-modified hematopoietic cells by a novel selective amplifier gene utilizing the erythropoietin receptor as a molecular switch

scientific article published on January 2004

In vivo expansion of transduced murine hematopoietic cells with a selective amplifier gene

scientific article published in March 2003

In vivo repopulation of cytoplasmically gene transferred hematopoietic cells by temperature-sensitive mutant of recombinant Sendai viral vector

scientific article published on 30 July 2007

Induced pluripotent stem cell reprogramming by integration-free Sendai virus vectors from peripheral blood of patients with craniometaphyseal dysplasia

scientific article

Induction of Gag-specific T-cell responses by therapeutic immunization with a Gag-expressing Sendai virus vector in macaques chronically infected with simian-human immunodeficiency virus

scientific article

Induction of a cross-reactive antibody response to influenza virus M2 antigen in pigs by using a Sendai virus vector

scientific article

Induction of efficient antitumor immunity using dendritic cells activated by recombinant Sendai virus and its modulation by exogenous IFN-beta gene

scientific article published on September 2006

Inhibition of choroidal neovascularization via brief subretinal exposure to a newly developed lentiviral vector pseudotyped with Sendai viral envelope proteins

scientific article

Inhibition of nuclear translocation of apoptosis-inducing factor is an essential mechanism of the neuroprotective activity of pigment epithelium-derived factor in a rat model of retinal degeneration.

scientific article published on 9 October 2008

Intramuscular gene transfer of FGF-2 attenuates endothelial dysfunction and inhibits intimal hyperplasia of vein grafts in poor-runoff limbs of rabbit

scientific article

Intranasal Sendai viral vector vaccination is more immunogenic than intramuscular under pre-existing anti-vector antibodies

scientific article published on 20 September 2011

Introduction of the green fluorescent protein gene into hematopoietic stem cells results in prolonged discrepancy of in vivo transduction levels between bone marrow progenitors and peripheral blood cells in nonhuman primates

scientific article published on 01 September 2002

Knockout serum replacement (KSR) has a suppressive effect on Sendai virus-mediated transduction of cynomolgus ES cells

scientific article published in September 2008

Naked Sendai virus vector lacking all of the envelope-related genes: reduced cytopathogenicity and immunogenicity

scientific article published on September 2006

New selective amplifier genes containing c-Mpl for hematopoietic cell expansion

scientific article published on March 2003

New type of Sendai virus vector provides transgene-free iPS cells derived from chimpanzee blood

scientific article

Newly-developed Sendai virus vector for retinal gene transfer: reduction of innate immune response via deletion of all envelope-related genes

scientific article published in February 2008

Non-transmissible Sendai virus encoding granulocyte macrophage colony-stimulating factor is a novel and potent vector system for producing autologous tumor vaccines

scientific article published on 18 October 2008

Nonendothelial mesenchymal cell-derived MCP-1 is required for FGF-2-mediated therapeutic neovascularization: critical role of the inflammatory/arteriogenic pathway.

scientific article

Nontransmissible virus-like particle formation by F-deficient sendai virus is temperature sensitive and reduced by mutations in M and HN proteins

scientific article

Novel treatment for lithium-induced nephrogenic diabetes insipidus rat model using the Sendai-virus vector carrying aquaporin 2 gene

scientific article published on 24 July 2008

Pigment Epithelium-Derived Factor Gene Therapy Targeting Retinal Ganglion Cell Injuries: Neuroprotection against Loss of Function in Two Animal Models ⬇️

scientific article published on March 17, 2011

Potent specific immune responses induced by prime-boost-boost strategies based on DNA, adenovirus, and Sendai virus vectors expressing gag gene of Chinese HIV-1 subtype B.

scientific article published on 22 September 2008

Prevalence of specific neutralizing antibodies against Sendai virus in populations from different geographic areas: implications for AIDS vaccine development using Sendai virus vectors

scientific article published in June 2011

Prevention of immune responses to human erythropoietin in cynomolgus monkeys (Macaca fascicularis)

scientific article published on 01 May 2006

Protective efficacy of an AIDS vaccine, a single DNA priming followed by a single booster with a recombinant replication-defective Sendai virus vector, in a macaque AIDS model

scientific article published on September 2003

Provision of continuous maturation signaling to dendritic cells by RIG-I-stimulating cytosolic RNA synthesis of Sendai virus

scientific article published on 27 December 2010

Pseudotyped lentivirus vectors derived from simian immunodeficiency virus SIVagm with envelope glycoproteins from paramyxovirus

scientific article

RIG-I Helicase-Independent Pathway in Sendai Virus-Activated Dendritic Cells Is Critical for Preventing Lung Metastasis of AT6.3 Prostate Cancer ⬇️

scientific article published on November 1, 2010

Recombinant Sendai virus vector induces complete remission of established brain tumors through efficient interleukin-2 gene transfer in vaccinated rats

scientific article

Recombinant Sendai virus vectors deleted in both the matrix and the fusion genes: efficient gene transfer with preferable properties

scientific article published on October 2004

Recombinant Sendai virus-mediated gene transfer into adult rat retinal tissue: efficient gene transfer by brief exposure

scientific article published on July 2002

Recombinant sendai virus-mediated gene transfer to adipose tissue-derived stem cells (ASCs).

scientific article published in January 2008

SOCS1 [corrected] inhibits HPV-E7-mediated transformation by inducing degradation of E7 protein

scientific article published on April 2004

Safe and efficient collection of cytokine-mobilized peripheral blood cells from cynomolgus monkeys (Macaca fascicularis) with human newborn-equivalent body weights

scientific article published on 01 October 2005

Safe and efficient methods of autologous hematopoietic stem cell transplantation for biomedical research in cynomolgus monkeys

scientific article published on 01 October 2002

Sendai viral vector mediated angiopoietin-1 gene transfer for experimental ischemic limb disease

scientific article

Sendai virus for cancer immunotherapy

scientific article published in January 2009

Sendai virus for gene therapy and vaccination.

scientific article

Sendai virus transgene in a novel gene therapy for laryngotracheal disease

scientific article published on 10 May 2013

Sendai virus vector-mediated gene transfer of glial cell line-derived neurotrophic factor prevents delayed neuronal death after transient global ischemia in gerbils

scientific article published in April 2003

Sendai virus vector-mediated transgene expression in the cochlea in vivo

scientific article published on 6 December 2006

Sendai virus-mediated gene delivery into hepatocytes via isolated hepatic perfusion

scientific article published in August 2006

Sendai virus-mediated gene transfer of GDNF reduces AIF translocation and ameliorates ischemic cerebral injury

scientific article

Stable retinal gene expression in nonhuman primates via subretinal injection of SIVagm-based lentiviral vectors

scientific article

Sustained and NK/CD4+ T cell-dependent efficient prevention of lung metastasis induced by dendritic cells harboring recombinant Sendai virus

scientific article published on 4 September 2009

Sustained transgene expression by human cord blood derived CD34+ cells transduced with simian immunodeficiency virus agmTYO1-based vectors carrying the human coagulation factor VIII gene in NOD/SCID mice

scientific article published in October 2004

Synergistic neuroprotective effect via simian lentiviral vector-mediated simultaneous gene transfer of human pigment epithelium-derived factor and human fibroblast growth factor-2 in rodent models of retinitis pigmentosa

scientific article

TLR7 ligand augments GM-CSF-initiated antitumor immunity through activation of plasmacytoid dendritic cells

scientific article published on 10 April 2014

The Sprouty-related protein, Spred, inhibits cell motility, metastasis, and Rho-mediated actin reorganization

scientific article

The nasal epithelium as a factory for systemic protein delivery

scientific article

Transgene-free disease-specific induced pluripotent stem cells from patients with type 1 and type 2 diabetes

scientific article published on 30 May 2012

Urokinase-targeted fusion by oncolytic Sendai virus eradicates orthotopic glioblastomas by pronounced synergy with interferon-β gene.

scientific article

VEGF function for upregulation of endogenous PlGF expression during FGF-2-mediated therapeutic angiogenesis.

scientific article published on 6 February 2008

VEGF-C regulates lymphangiogenesis and capillary stability by regulation of PDGF-B.

scientific article

[Mucosal immunotherapy for alzheimer's disease with viral vectors].

scientific article

Paulina is supported by:

About Paulina

Help