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List of works by Hidenori Akutsu

A Distinct Role for Pin1 in the Induction and Maintenance of Pluripotency ⬇️

scientific article published on February 4, 2011

A medium-chain fatty acid as an alternative energy source in mouse preimplantation development.

scientific article

A melanocyte--melanoma precursor niche in sweat glands of volar skin

scientific article published on 4 September 2014

A synthetic nanofibrillar matrix promotes in vitro hepatic differentiation of embryonic stem cells and induced pluripotent stem cells

scientific article published on 7 October 2013

A xenogeneic-free system generating functional human gut organoids from pluripotent stem cells

scientific article

Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells

scientific article

Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus cell nuclei

scientific article

Age-associated alteration of gene expression patterns in mouse oocytes.

scientific article published on 18 August 2004

Age-associated telomere shortening in mouse oocytes

scientific article

An efficient method for differentiation of human induced pluripotent stem cells into hepatocyte-like cells retaining drug metabolizing activity

scientific article published on 10 December 2013

Assessment of the Safety of Chondrocyte Sheet Implantation for Cartilage Regeneration

scientific article published on 11 November 2015

Autonomous trisomic rescue of Down syndrome cells

scientific article published on 13 February 2019

Can Human Embryonic Stem Cell-Derived Stromal Cells Serve a Starting Material for Myoblasts?

scientific article

Chemical inhibition of sulfation accelerates neural differentiation of mouse embryonic stem cells and human induced pluripotent stem cells ⬇️

scientific article published on September 25, 2010

Chromatin condensation of Xist genomic loci during oogenesis in mice

scientific article

Clinical applications of human embryonic stem cell

scientific article published on 01 June 2015

DNA Methylation Dynamics in Human Induced Pluripotent Stem Cells over Time ⬇️

scientific article published on May 26, 2011

DNA hypermethylation enhanced telomerase reverse transcriptase expression in human-induced pluripotent stem cells

scientific article published on 4 November 2017

De novo DNA methyltransferases DNMT3A and DNMT3B are essential for XIST silencing for erosion of dosage compensation in pluripotent stem cells

scientific article

Defining Hypo-Methylated Regions of Stem Cell-Specific Promoters in Human iPS Cells Derived from Extra-Embryonic Amnions and Lung Fibroblasts ⬇️

scientific article published on September 27, 2010

Derivation of human decidua-like cells from amnion and menstrual blood

scientific article published on 08 April 2014

Differentiation of Human Induced Pluripotent Stem Cells into Functional Enterocyte-like Cells Using a Simple Method ⬇️

scientific article published on July 2, 2013

Early Senescence Is Not an Inevitable Fate of Human-Induced Pluripotent Stem-Derived Cells ⬇️

scientific article published on June 30, 2011

Efficient generation of hepatoblasts from human ES cells and iPS cells by transient overexpression of homeobox gene HEX.

scientific article

Efficient production of trophoblast lineage cells from human induced pluripotent stem cells

scientific article published on 13 March 2017

Efficient reprogramming of human and mouse primary extra-embryonic cells to pluripotent stem cells

scientific article published on 13 November 2009

Elucidating nuclear reprogramming mechanisms: taking a synergistic approach

scientific article published on January 2008

Epigenetic and transcriptional features of the novel human imprinted lncRNA GPR1AS suggest it is a functional ortholog to mouse Zdbf2linc

scientific article published on 09 May 2013

Epigenetic-scale comparison of human iPSCs generated by retrovirus, Sendai virus or episomal vectors

Esg1, expressed exclusively in preimplantation embryos, germline, and embryonic stem cells, is a putative RNA-binding protein with broad RNA targets

scientific journal article

Establishment and directed differentiation of induced pluripotent stem cells from glycogen storage disease type Ib patient

scientific article published on 28 October 2013

Exploring trophoblast-specific Tead4 enhancers through chromatin conformation capture assays followed by functional screening

scientific article published on 01 January 2020

Feeder-Free and Serum-Free Production of Hepatocytes, Cholangiocytes, and Their Proliferating Progenitors from Human Pluripotent Stem Cells: Application to Liver-Specific Functional and Cytotoxic Assays ⬇️

scientific article published on March 2, 2012

Fetal Therapy Model of Myelomeningocele with Three-Dimensional Skin Using Amniotic Fluid Cell-Derived Induced Pluripotent Stem Cells

scientific article

Generation and Profiling of 2,135 Human ESC Lines for the Systematic Analyses of Cell States Perturbed by Inducing Single Transcription Factors

scientific article published on 01 May 2020

Generation of primitive neural stem cells from human fibroblasts using a defined set of factors

scientific article published on 21 October 2015

Glycome diagnosis of human induced pluripotent stem cells using lectin microarray

scientific article

Human cytomegalovirus downregulates SLITRK6 expression through IE2.

scientific article published on 16 August 2016

Human cytomegalovirus induces apoptosis in neural stem/progenitor cells derived from induced pluripotent stem cells by generating mitochondrial dysfunction and endoplasmic reticulum stress.

scientific article published on 21 October 2013

Human embryonic stem cells

scientific article published on 01 January 2006

Identification of an epigenetic signature in human induced pluripotent stem cells using a linear machine learning model

scientific article published on 12 October 2020

Imbalance between the expression dosages of X-chromosome and autosomal genes in mammalian oocytes

scientific article

Immortalization of human hepatocytes from biliary atresia with CDK4R24C, cyclin D1, and TERT for cytochrome P450 induction testing

scientific article published on 15 October 2020

Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei

scientific article published in April 2003

Induced cancer stem-like cells as a model for biological screening and discovery of agents targeting phenotypic traits of cancer stem cell

scientific article

Intestinal Organoids Generated from Human Pluripotent Stem Cells

scientific article published on 27 December 2019

Investigation of telomere length dynamics in induced pluripotent stem cells using quantitative fluorescence in situ hybridization.

scientific article published on 5 August 2013

Involvement of a novel preimplantation-specific gene encoding the high mobility group box protein Hmgpi in early embryonic development

scientific journal article

In vivo maturation of human embryonic stem cell-derived teratoma over time

scientific article published on 25 July 2016

Lectin microarray analysis of pluripotent and multipotent stem cells

scientific article published on 13 December 2010

Lipid rafts enriched in monosialylGb5Cer carrying the stage-specific embryonic antigen-4 epitope are involved in development of mouse preimplantation embryos at cleavage stage ⬇️

scientific article published on April 14, 2011

Maintenance of Xist Imprinting Depends on Chromatin Condensation State and Rnf12 Dosage in Mice

scientific article

Maintenance of pluripotency and self-renewal ability of mouse embryonic stem cells in the absence of tetraspanin CD9.

scientific article published on 28 August 2009

Manipulation of Xist Imprinting in Mouse Preimplantation Embryos

scientific article published on 01 January 2018

Mesenchymal to embryonic incomplete transition of human cells by chimeric OCT4/3 (POU5F1) with physiological co-activator EWS.

scientific article

Method for evaluation of human induced pluripotent stem cell quality using image analysis based on the biological morphology of cells.

scientific article published in October 2017

MicroRNA-199a-3p, microRNA-193b, and microRNA-320c are correlated to aging and regulate human cartilage metabolism

scientific article published on 01 June 2012

Mitochondrial Genetic Drift after Nuclear Transfer in Oocytes

scientific article published on 16 August 2020

Odf2 haploinsufficiency causes a new type of decapitated and decaudated spermatozoa, Odf2-DDS, in mice

scientific article published on 03 October 2019

Oocyte activation ability correlates with head flatness and presence of perinuclear theca substance in human and mouse sperm

scientific article published on 16 July 2009

Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines

scientific article published in February 2009

Organoids recapitulate organs?

scientific article published on 17 January 2018

Podocalyxin is a glycoprotein ligand of the human pluripotent stem cell-specific probe rBC2LCN.

scientific article published on 22 March 2013

Possible involvement of CD81 in acrosome reaction of sperm in mice

scientific article published in January 2008

Preferential localization of SSEA-4 in interfaces between blastomeres of mouse preimplantaion embryos

scientific article published on 26 October 2007

Production of a non-triple helical collagen alpha chain in transgenic silkworms and its evaluation as a gelatin substitute for cell culture

scientific article published on August 2010

Production of functional classical brown adipocytes from human pluripotent stem cells using specific hemopoietin cocktail without gene transfer

article

Production of inbred and hybrid transgenic mice carrying large (> 200 kb) foreign DNA fragments by intracytoplasmic sperm injection

scientific article published in November 2005

Removal of reprogramming transgenes improves the tissue reconstitution potential of keratinocytes generated from human induced pluripotent stem cells

scientific article published on 14 July 2014

Research and Development Strategy for Future Embryonic Stem Cell-Based Therapy in Japan

scientific article published on 23 September 2020

Spatiotemporal dynamics of OCT4 protein localization during preimplantation development in mice.

scientific article published on 05 August 2016

Stability of genomic imprinting in human induced pluripotent stem cells.

scientific article

The combination of dibenzazepine and a DOT1L inhibitor enables a stable maintenance of human naïve-state pluripotency in non-hypoxic conditions

scientific article

The fusing ability of sperm is bestowed by CD9-containing vesicles released from eggs in mice

scholarly article

The hsa-miR-302 cluster controls ectodermal differentiation of human pluripotent stem cell via repression of DAZAP2

scientific article published on 25 May 2020

The role of maternal-specific H3K9me3 modification in establishing imprinted X-chromosome inactivation and embryogenesis in mice

scientific article

The serine 106 residue within the N-terminal transactivation domain is crucial for Oct4 function in mice

scientific article published on 7 March 2017

Transcriptome analysis of mouse stem cells and early embryos

scientific article

Transcriptomic features of trophoblast lineage cells derived from human induced pluripotent stem cells treated with BMP 4

scientific article published on 09 October 2019

What can we learn from gene expression profiling of mouse oocytes?

scientific article published on May 2008

Xenogeneic-free defined conditions for derivation and expansion of human embryonic stem cells with mesenchymal stem cells.

scientific article published on 19 February 2015

Zscan5b Deficiency Impairs DNA Damage Response and Causes Chromosomal Aberrations during Mitosis

scientific article published on 30 May 2019

[Osteogenesis and chondrogenesis from a stem cell source]

scientific article published on 01 December 2008

α2-6 sialylation is a marker of the differentiation potential of human mesenchymal stem cells

scientific article published on 02 April 2016

β-Catenin Functions Pleiotropically in Differentiation and Tumorigenesis in Mouse Embryo-Derived Stem Cells ⬇️

scientific article published on May 14, 2013

β-catenin is a molecular switch that regulates transition of cell-cell adhesion to fusion ⬇️

scientific article published on August 19, 2011

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