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List of works by David Hockenbery

2-Methoxy antimycin reveals a unique mechanism for Bcl-x(L) inhibition

scientific article

A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells

scientific article

A Metabolomics Study of BPTES Altered Metabolism in Human Breast Cancer Cell Lines.

scientific article

A mitochondrial Achilles' heel in cancer?

scientific article published in July 2002

A randomized, placebo-controlled trial of oral beclomethasone dipropionate as a prednisone-sparing therapy for gastrointestinal graft-versus-host disease.

scientific article

Abstract 1981: Immune related liver toxicity and potential risk factors: A case-control study

scientific article published in 2022

Activation of NF-kappaB by palmitate in endothelial cells: a key role for NADPH oxidase-derived superoxide in response to TLR4 activation

scientific article published on 18 June 2009

An unsupervised MVA method to compare specific regions in human breast tumor tissue samples using ToF-SIMS

scientific article

Analysis of the Myc-induced pancreatic β cell islet tumor microenvironment using imaging ToF-SIMS

scientific article published on 28 August 2018

Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3.

scientific article

BCL-2 and BCL-XL restrict lineage choice during hematopoietic differentiation

scientific article published on 28 April 2003

BCL-2 suppresses ceramide-induced cell killing

scientific article published on 01 January 1996

BCL-2, a novel regulator of apoptosis

scientific article published on January 1996

BCL-XL dimerization by three-dimensional domain swapping

scientific article

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death

scientific article published on August 1991

Bak to basics of colonocyte renewal

scientific article published on 22 January 2009

Bcl-2 Slowsin VitroBreast Cancer Growth Despite Its Antiapoptotic Effect ⬇️

scientific article published on April 1, 1998

Bcl-2 family proteins as regulators of oxidative stress

scientific article published on 24 December 2008

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

scientific article (publication date: 22 October 1993)

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

scientific article (publication date: 22 November 1990)

Bcl-2 maintains B cell memory

scientific article

Bcl-2 protooncogene expression in cervical carcinoma cell lines containing inactive p53.

scientific article published in March 1995

Bcl-2-related proteins as drug targets

scientific article

Bcl-2-related survival proteins

scientific article published on 09 June 2006

Bcl-2: B cell life, death and neoplasia

scientific article published on 01 January 1990

Bcl-XL Mutations Suppress Cellular Sensitivity to Antimycin A ⬇️

scientific article published on October 8, 2003

Biophysical characterization of recombinant human Bcl-2 and its interactions with an inhibitory ligand, antimycin A.

scientific article published on April 2001

Blood and Gastric FOXP3+ T Cells Are Not Decreased in Human Gastric Graft-versus-Host Disease ⬇️

scientific article published on September 24, 2010

Caspase-3 and inhibitor of apoptosis protein(s) interactions in Saccharomyces cerevisiae and mammalian cells

scientific article published on September 2000

Caspase-3 inhibits growth in Saccharomyces cerevisiae without causing cell death

scientific article published on 01 March 1999

Colonic mucosal and exfoliome transcriptomic profiling and fecal microbiome response to a flaxseed lignan extract intervention in humans

scientific article published on 01 August 2019

Competitive inhibition of benzodiazepine binding by fractions from porcine brain ⬇️

scientific article published on December 1, 1978

Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer

scientific article

Conditional Disruption of Raptor Reveals an Essential Role for mTORC1 in B Cell Development, Survival, and Metabolism.

scientific article published on 12 August 2016

Constitutive expression of human Bcl-2 modulates nitrogen mustard and camptothecin induced apoptosis

scientific article published on April 1993

Cyclin I activates Cdk5 and regulates expression of Bcl-2 and Bcl-XL in postmitotic mouse cells

scientific article published on September 2009

Defining apoptosis

scientific article published on January 1995

Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines.

scientific article published on May 1990

Differential effects of bexarotene on intrinsic and extrinsic pathways in TRAIL-induced apoptosis in two myeloid leukemia cell lines

scientific article published on May 2007

Differential responses of FLIPLong and FLIPShort-overexpressing human myeloid leukemia cells to TNF-alpha and TRAIL-initiated apoptotic signals

scientific article published on 05 October 2008

Disruption of Fnip1 Reveals a Metabolic Checkpoint Controlling B Lymphocyte Development ⬇️

scientific article published on May 17, 2012

Distinct Alterations in Mitochondrial Mass and Function Characterize Different Models of Apoptosis ⬇️

scientific article published on March 15, 1998

Down-regulation of apurinic/apyrimidinic endonuclease expression is associated with the induction of apoptosis in differentiating myeloid leukemia cells.

scientific article published on April 1997

Dysregulated bcl-2 expression inhibits apoptosis but not differentiation of retinoic acid-induced HL-60 granulocytes.

scientific article published on July 1994

Efficacy of neodymium:YAG laser therapy for gastric antral vascular ectasia (GAVE) following hematopoietic cell transplant

scientific article published in January 2006

Endothelial inflammation induced by excess glucose is associated with cytosolic glucose 6-phosphate but not increased mitochondrial respiration

scientific article published on 14 February 2009

Enzyme-Cleavable Polymeric Micelles for the Intracellular Delivery of Proapoptotic Peptides.

scientific article

Expression of Bcl-2 family during liver regeneration and identification of Bcl-x as a delayed early response gene

scientific journal article

Fibrosing cholestatic hepatitis C after hematopoietic cell transplantation: report of 3 fatal cases

scientific article published on February 2015

Flow cytometric measurement of mitochondrial mass and function: A novel method for assessing chemoresistance ⬇️

scientific article published on April 1, 1998

Fnip1 regulates skeletal muscle fiber type specification, fatigue resistance, and susceptibility to muscular dystrophy

scientific article

Forecast: rough seas for leukemia

scientific article published on 01 March 2014

Gastrointestinal graft-versus-host disease in recipients of autologous hematopoietic stem cells: incidence, risk factors, and outcome

scientific article published in February 2006

HIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition ⬇️

scientific article published on March 23, 2012

Hsp90 inhibition decreases mitochondrial protein turnover

scientific article

Identification of androgen-coregulated protein networks from the microsomes of human prostate cancer cells

scientific article

Identification of genes with abnormal expression changes in acute myeloid leukemia

scientific article published on January 2008

Immunolocalization of the Bcl-2 protein within hematopoietic neoplasms

scientific article published on 01 August 1991

Induction of apoptosis using inhibitors of lysophosphatidic acid acyltransferase-beta and anti-CD20 monoclonal antibodies for treatment of human non-Hodgkin's lymphomas.

scientific article published on July 2005

Induction of the Warburg effect by Kaposi's sarcoma herpesvirus is required for the maintenance of latently infected endothelial cells

scientific article

Inhibition of vaccinia virus replication by nitazoxanide

scientific article published on 3 April 2018

Intracellular delivery system for antibody-Peptide drug conjugates

scientific article published on 11 February 2015

Investigating Neoplastic Progression of Ulcerative Colitis with Label-Free Comparative Proteomics ⬇️

scientific article published on October 20, 2010

Life and death in otolaryngology: mechanisms of apoptosis and its role in the pathology and treatment of disease

scientific article

Lipid analysis of eight human breast cancer cell lines with ToF-SIMS.

scientific article

Loss of FANCC function is associated with failure to inhibit late firing replication origins after DNA cross-linking

scientific article published on 6 April 2007

Loss of Fnip1 alters kidney developmental transcriptional program and synergizes with TSC1 loss to promote mTORC1 activation and renal cyst formation.

scientific article published on 13 June 2018

Lymphocytic gastritis resembling graft-vs.-host disease following autologous hematopoietic cell transplantation ⬇️

scientific article published on 01 January 1998

MMPs in unusual places

scientific article published on October 2006

MYC and mitochondrial biogenesis

scientific article published on May 2014

Major histocompatibility complex class II-mediated inhibition of hematopoiesis in long-term marrow cultures involves apoptosis and is prevented by c-kit ligand ⬇️

scientific article published on 01 November 1995

Metabolic Reprogramming and Dependencies Associated with Epithelial Cancer Stem Cells Independent of the Epithelial-Mesenchymal Transition Program

scientific article published on 2 February 2016

Mitochondria and apoptosis: new therapeutic targets

scientific article

Mitochondrial Proliferation and Paradoxical Membrane Depolarization during Terminal Differentiation and Apoptosis in a Human Colon Carcinoma Cell Line ⬇️

scientific article published on July 28, 1997

Mitochondrial functions in stem cells

scientific article

Mutant IDH1 regulates the tumor-associated immune system in gliomas

scientific article published on 2 May 2017

Myc's Mastery of Mitochondrial Mischief ⬇️

scientific article published on January 1, 2003

Myc-dependent Mitochondrial Generation of Acetyl-CoA Contributes to Fatty Acid Biosynthesis and Histone Acetylation during Cell Cycle Entry ⬇️

scientific article published on September 2, 2010

Myc-dependent mitochondrial generation of acetyl-CoA contributes to fatty acid biosynthesis and histone acetylation during cell cycle entry

scientific article published in March 2011

Oral beclomethasone dipropionate for treatment of human intestinal graft-versus-host disease

scientific article published on 01 December 1995

Oral beclomethasone dipropionate for treatment of intestinal graft-versus-host disease: A randomized, controlled trial ⬇️

scientific article published on 01 July 1998

Oral beclomethasone dipropionate in gastrointestinal graft-versus-host disease

scientific article published in September 2007

Pan-cancer transcriptional signatures predictive of oncogenic mutations reveal that Fbw7 regulates cancer cell oxidative metabolism

scientific article published on 07 May 2018

Pathological assessment of gastrointestinal biopsies from patients with idelalisib-associated diarrhea and colitis

scientific article published on 23 March 2018

Pericrypt eosinophilic enterocolitis and chronic diarrhea ⬇️

scientific article published on 01 July 1992

Pilot study of lithium to restore intestinal barrier function in severe graft-versus-host disease

scientific article

Prevention of Fas-mediated hepatic failure by transferrin

scientific article published on March 2004

Primitive human hematopoietic precursors express Bcl-x but not Bcl-2

scientific article published on 01 August 1995

Reactive oxygen species in chick hair cells after gentamicin exposure in vitro

scientific article published in February 1997

Reduced Cytochrome c Is an Essential Regulator of Sustained Insulin Secretion by Pancreatic Islets ⬇️

scientific article published on March 10, 2011

Response of Steroid-Refractory Acute GVHD to α1-Antitrypsin

scientific article

Severe gastrointestinal bleeding after hematopoietic cell transplantation, 1987-1997: incidence, causes, and outcome

scientific article published on 01 February 2001

Small-molecule inhibitors of Bcl-2.

scientific article published on December 2006

Spontaneous Tumor Regression in Tasmanian Devils Associated with RASL11A Activation

scientific article published on 18 June 2020

Successful medical treatment of intestinal ulceration caused by Rhizopus microsporus

scientific article published on 01 October 2003

Suppression of p53 function in normal human mammary epithelial cells increases sensitivity to extracellular matrix–induced apoptosis ⬇️

scientific article published on October 22, 2001

Targeted therapies for epithelial cancers: in vivo efficacy of the BCL-2/BCL-XL inhibitor 2-MeAA.

scientific article published on 15 March 2007

Targeting mitochondria for cancer therapy

scientific article published on 01 June 2010

The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins

scientific article published on August 1992

The bcl-2 oncogene and apoptosis

scientific article published on December 1, 1992

The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition

scientific article

The oncogene c-Myc coordinates regulation of metabolic networks to enable rapid cell cycle entry

scientific journal article

The role of apoptosis during intestinal adaptation after small bowel resection

scientific article published on 01 January 2000

ToF-SIMS of tissues: "lessons learned" from mice and women

scientific article

Warburg and Crabtree Effects in Premalignant Barrett's Esophagus Cell Lines with Active Mitochondria ⬇️

scientific article published on February 27, 2013

bcl-2 in cancer, development and apoptosis.

scientific article published on January 1994

bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes ⬇️

scientific article published on November 29, 1991

bcl‐2, a novel reguator of cell death ⬇️

scientific article published on July 1, 1995

c-MYC apoptotic function is mediated by NRF-1 target genes

scientific article

c-Myc activates multiple metabolic networks to generate substrates for cell-cycle entry

scientific article published on 18 May 2009

α-1-Antitrypsin (AAT)-modified donor cells suppress GVHD but enhance the GVL effect: a role for mitochondrial bioenergetics

scientific article

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