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List of works by Ester Simeone

A monocentric phase I study of vemurafenib plus cobimetinib plus PEG-interferon (VEMUPLINT) in advanced melanoma patients harboring the V600BRAF mutation

scientific article published on 06 January 2021

Abscopal effects of radiotherapy on advanced melanoma patients who progressed after ipilimumab immunotherapy.

scientific article

Abstract 4017: Anti-tumor activity of a BRAF inhibitor and IFNα combination in BRAF mutant melanoma

scientific article published on 15 July 2016

Adjuvant treatment of malignant melanoma: where are we?

scientific article

Analysis of T and NK cells immune response in Ipilimumab treated Melanoma patients.

scientific article published on 15 January 2015

Anti-PD-1 and PD-L1 antibodies in metastatic melanoma

scientific article published on 21 November 2017

Anti-PD1 and anti-PD-L1 in the treatment of metastatic melanoma.

scientific article published on 25 February 2015

Antitumor Activity of BRAF Inhibitor and IFNα Combination in BRAF-Mutant Melanoma

scientific article published on 05 February 2016

Assessing a novel immuno-oncology-based combination therapy: Ipilimumab plus electrochemotherapy

scientific article published on 22 May 2015

Association of CTLA-4 Gene Variants with Response to Therapy and Long-term Survival in Metastatic Melanoma Patients Treated with Ipilimumab: An Italian Melanoma Intergroup Study.

scientific article published on 12 April 2017

Baseline Biomarkers for Outcome of Melanoma Patients Treated with Pembrolizumab

scientific article

Baseline neutrophil-to-lymphocyte ratio (NLR) and derived NLR could predict overall survival in patients with advanced melanoma treated with nivolumab

CTLA-4 gene variant -1661A>G may predict the onset of endocrine adverse events in metastatic melanoma patients treated with ipilimumab

article

Clinical Experiences With Anti-CD137 and Anti-PD1 Therapeutic Antibodies ⬇️

scientific article published on October 1, 2010

Clinical experience with ipilimumab 3 mg/kg: real-world efficacy and safety data from an expanded access programme cohort

scientific article

Clinicopathologic features and surgical management of primary umbilical melanoma: a case series.

scientific article

Combination Treatment of Patients with BRAF-Mutant Melanoma: A New Standard of Care

scientific article published on 6 January 2017

Combination therapy with ipilimumab and electrochemotherapy: preliminary efficacy results and correlation with immunological parameters.

scientific article published on 6 May 2014

Combined vemurafenib and fotemustine in patients with BRAFV600 melanoma progressing on vemurafenib

scientific article

Complete response to nivolumab monotherapy in a treatment-naive, BRAF wild-type patient with advanced mucosal melanoma and elevated lactate dehydrogenase: a case report from a phase III trial

scientific article published on 7 September 2016

Computer-aided diagnosis of melanocytic lesions

scientific article published in November 2005

Correlation between BRAF mutational status and clinical response to pembrolizumab in advanced melanoma patients

scientific article published on 4 November 2015

Correlation between immune-related adverse events and response to pembrolizumab in advanced melanoma patients.

scientific article published on 4 November 2015

Correlation between previous treatment with BRAF inhibitors and clinical response to pembrolizumab in patients with advanced melanoma

scientific article published on 19 January 2017

Corrigendum: Association of CTLA-4 Gene Variants with Response to Therapy and Long-term Survival in Metastatic Melanoma Patients Treated with Ipilimumab: An Italian Melanoma Intergroup Study. ⬇️

scientific article published on 2 March 2018

Do BRAF inhibitors select for populations with different disease progression kinetics?

scientific article

Efficacy and safety of ipilimumab in patients with advanced melanoma and brain metastases

scientific article

Efficacy of radiotherapy in patients on progression after treatment with ipilimumab 3 mg/kg.

scientific article published on 6 May 2014

Electrochemotherapy efficacy evaluation for treatment of locally advanced stage III cutaneous squamous cell carcinoma: a 22-cases retrospective analysis.

scientific article

Electrochemotherapy in melanoma patients: a single institution experience

scientific article published on 18 May 2015

Erratum to: Immunological and biological changes during ipilimumab treatment and their potential correlation with clinical response and survival in patients with advanced melanoma

scholarly article published in Cancer Immunology, Immunotherapy

Expression of CXCR4 Predicts Poor Prognosis in Patients with Malignant Melanoma

scientific article published on 01 March 2005

FKBP51s signature in peripheral blood mononuclear cells of melanoma patients as a possible predictive factor for immunotherapy.

scientific article published on 22 April 2017

Factors predicting the occurrence of germline mutations in candidate genes among patients with cutaneous malignant melanoma from South Italy

scientific article published on 19 October 2006

Gemcitabine versus bacille Calmette-Guérin after initial bacille Calmette-Guérin failure in non-muscle-invasive bladder cancer: a multicenter prospective randomized trial

scientific article published in April 2010

High expression of a spliced variant of FKBP51 in peripheral blood mononuclear cells of melanoma patients may be related to PDL-1 on tumour and predictive of response to Ipilimumab

Human melanoma metastases express functional CXCR4.

scientific article published on April 2006

IL-15, TIM-3 and NK cells subsets predict responsiveness to anti-CTLA-4 treatment in melanoma patients

scientific article published on 7 December 2016

Immunological and biological changes during ipilimumab treatment and their potential correlation with clinical response and survival in patients with advanced melanoma

article

Immunomodulating antibodies in the treatment of metastatic melanoma: The experience with anti-CTLA-4, anti-CD137, and anti-PD1 ⬇️

scientific article published on April 23, 2012

Immunomodulatory pathways regulate expression of a spliced FKBP51 isoform in lymphocytes of melanoma patients.

scientific article published on 13 May 2015

Immunotherapy Bridge 2017 and Melanoma Bridge 2017: meeting abstracts

scientific article published on 15 January 2018

Immunotherapy in metastatic melanoma: a novel scenario of new toxicities and their management

scientific article published on 08 November 2019

Impact of COVID-19 outbreak on cancer immunotherapy in Italy: a survey of young oncologists

scientific article published on 01 October 2020

Interferon alpha for the adjuvant treatment of melanoma: review of international literature and practical recommendations from an expert panel on the use of interferon

scientific article published on 19 December 2013

Ipilimumab and fotemustine in patients with advanced melanoma (NIBIT-M1): an open-label, single-arm phase 2 trial

scientific article

Long-lasting response to electrochemotherapy in melanoma patients with cutaneous metastasis

scientific article

Long-term response after electrochemotherapy in patients with relapsed or refractory cutaneous melanoma.

scientific article published on 6 May 2014

Low-dose temozolomide before dendritic-cell vaccination reduces (specifically) CD4+CD25++Foxp3+ regulatory T-cells in advanced melanoma patients ⬇️

scientific article published on May 31, 2013

MEK Inhibitors in the Treatment of Metastatic Melanoma and Solid Tumors

scientific article published on 23 May 2017

MISIPI study: Melanoma ImmunoScore evaluation in patients treated with IPIlimumab.

scientific article published on 6 May 2014

Marker utility for combination therapy

scientific article published on January 2014

Neoplastic leptomeningitis presenting in a melanoma patient treated with dabrafenib (a V600EBRAF inhibitor): a case report

scientific article

Nevoid melanoma of the vagina: report of one case diagnosed on thin layer cytological preparations

scientific article published on 3 July 2007

Nivolumab for the treatment of small cell lung cancer

scientific article published on 29 October 2019

Novel mechanisms and therapeutic approaches in melanoma: targeting the MAPK pathway

scientific article (publication date: June 2015)

PD-L1 expression with immune-infiltrate evaluation and outcome prediction in melanoma patients treated with ipilimumab

scientific article published on 05 September 2018

PD-L1 inhibitors in the pipeline: Promise and progress

scientific article published on 21 September 2017

Pegylated arginine deiminase treatment of patients with metastatic melanoma: results from phase I and II studies

scientific article published in October 2005

Phase II trial (BREAK-2) of the BRAF inhibitor dabrafenib (GSK2118436) in patients with metastatic melanoma

scientific article

Phase III randomized study of fotemustine and dacarbazine versus dacarbazine with or without interferon-α in advanced malignant melanoma

scientific article published on 13 February 2013

Proteomic test for anti-PD-1 checkpoint blockade treatment of metastatic melanoma with and without BRAF mutations

scientific article published on 29 March 2019

Regulatory T cell frequency in patients with melanoma with different disease stage and course, and modulating effects of high-dose interferon-alpha 2b treatment

scientific article

Sequencing of BRAF inhibitors and ipilimumab in patients with metastatic melanoma: a possible algorithm for clinical use.

scientific article

Sequential treatment with ipilimumab and BRAF inhibitors in patients with metastatic melanoma: data from the Italian cohort of the ipilimumab expanded access program

scientific article

Serial detection of circulating tumour cells by reverse transcriptase-polymerase chain reaction assays is a marker for poor outcome in patients with malignant melanoma

scientific article

Serious haematological toxicity during and after ipilimumab treatment: a case series.

scientific article

Soluble CTLA-4 as a favorable predictive biomarker in metastatic melanoma patients treated with ipilimumab: an Italian melanoma intergroup study

article

Soluble interleukin-2 receptor in stage I–III melanoma

scientific article published on 01 February 2006

Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer

scientific article published on 01 May 2020

Systems biology analysis of immune signaling in peripheral blood mononuclear cells (PBMC) of melanoma patients receiving ipilimumab; basis for clinical response biomarker identification ⬇️

scientific article published on 7 November 2013

Systems biology analysis of immune signaling in peripheral blood mononuclear cells (PBMC) of melanoma patients receiving ipilimumab; basis for response biomarker identification.

scientific article published on 6 May 2014

Temozolomide and cisplatin in avdanced malignant melanoma.

scientific article published in March 2005

The abscopal effect: efficacy of radiotherapy in patients on progression after treatment with ipilimumab 3 mg/kg

scientific article published on 7 November 2013

The role of BRAF V600 mutation in melanoma

scientific article

The role of MEK inhibitors in the treatment of metastatic melanoma

scientific article published on March 2014

The role of spectrophotometry in the diagnosis of melanoma

scientific article

The use of interferon in melanoma patients: a systematic review

scientific article

Update on PEG-interferon α-2b as adjuvant therapy in melanoma

scientific article published on September 1, 2012

Vemurafenib beyond progression in a patient with metastatic melanoma: a case report

scientific article published in April 2015

Vemurafenib in BRAFV600 mutated metastatic melanoma: a subanalysis of the Italian population of a global safety study.

scientific article published on January 2015

Vemurafenib plus cobimetinib in the treatment of mutated metastatic melanoma: the CoBRIM trial.

scientific article published on 10 August 2015

[Cutaneous squamous cell carcinoma: immunotherapy for locally advanced and metastatic disease]

scientific article published on 01 July 2020

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