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List of works by Huib N. Caron

123I-MIBG scintigraphy and 18F-FDG-PET imaging for diagnosing neuroblastoma

scientific article

A biology-driven approach identifies the hypoxia gene signature as a predictor of the outcome of neuroblastoma patients

scientific article published on 12 July 2010

A coding variant in RARG confers susceptibility to anthracycline-induced cardiotoxicity in childhood cancer

scientific article

A prospective study on the characteristics and subjects of pediatric palliative care case management provided by a hospital based palliative care team

scientific article

A worldwide collaboration to harmonize guidelines for the long-term follow-up of childhood and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group.

scientific article published on 31 December 2012

AMORE protocol in pediatric head and neck rhabdomyosarcoma: descriptive analysis of failure patterns

scientific article

Acute malnutrition is common in Malawian patients with a Wilms tumour: A role for peanut butter

scientific article published in December 2009

Adverse events of local treatment in long-term head and neck rhabdomyosarcoma survivors after external beam radiotherapy or AMORE treatment

scientific article published on 18 May 2015

Age Dependency of the Prognostic Impact of Tumor Genomics in Localized Resectable MYCN-Nonamplified Neuroblastomas. Report From the SIOPEN Biology Group on the LNESG Trials and a COG Validation Group

scientific article published on 09 September 2020

Antagonistic effects of sequential administration of BL1521, a histone deacetylase inhibitor, and gemcitabine to neuroblastoma cells

scientific article

Anthracycline cardiotoxicity in children

scientific article published in July 2004

Anthracycline-induced cardiotoxicity: comparison of recommendations for monitoring cardiac function during therapy in paediatric oncology trials

scientific article published on 29 September 2006

Cardiac Function in 5-Year Survivors of Childhood Cancer—Reply

Cardiac function in 5-year survivors of childhood cancer: a long-term follow-up study

scientific article published on July 2010

Cardioprotective interventions for cancer patients receiving anthracyclines

scientific article (publication date: 15 June 2011)

Cardioprotective interventions for cancer patients receiving anthracyclines

scientific article (published 2008-04-23)

Catecholamines profiles at diagnosis: Increased diagnostic sensitivity and correlation with biological and clinical features in neuroblastoma patients

scientific article published on 3 January 2017

Clinical heart failure during pregnancy and delivery in a cohort of female childhood cancer survivors treated with anthracyclines

scientific article published on 17 August 2006

Clinical heart failure in a cohort of children treated with anthracyclines: a long-term follow-up study

scientific article published on 20 September 2006

Coping and family functioning predict longitudinal psychological adaptation of siblings of childhood cancer patients

scientific article

Copy number defects of G1-cell cycle genes in neuroblastoma are frequent and correlate with high expression of E2F target genes and a poor prognosis

scientific article published on 27 October 2011

Course of life of survivors of childhood cancer is related to quality of life in young adulthood

scientific article published in January 2007

Cyclin D1 and CDK4 activity contribute to the undifferentiated phenotype in neuroblastoma

scientific article published in April 2008

Cyclin-Dependent Kinase Inhibitor AT7519 as a Potential Drug for MYCN-Dependent Neuroblastoma

scientific article published on 22 July 2015

Cyclopentenyl cytosine primes SK-N-BE(2)c neuroblastoma cells for cytarabine toxicity

scientific article published on January 2003

Cyclopentenyl cytosine-induced activation of deoxycytidine kinase increases gemcitabine anabolism and cytotoxicity in neuroblastoma

scientific article published on 5 November 2005

DNA-Dependent Protein Kinase As Molecular Target for Radiosensitization of Neuroblastoma Cells

scientific article published on 30 December 2015

Detecting minimal residual disease in neuroblastoma: the superiority of a panel of real-time quantitative PCR markers

scientific article

Determination of the deoxycytidine kinase activity in cell homogenates with a non-radiochemical assay using reversed-phase high performance liquid chromatography; Identification of a novel metabolite of 2-chlorodeoxyadenosine

scientific article published on June 2004

Development of a real-time polymerase chain reaction assay for prediction of the uptake of meta-[(131)I]iodobenzylguanidine by neuroblastoma tumors.

scientific article published on August 2003

Dickkopf-3 expression is a marker for neuroblastic tumor maturation and is down-regulated by MYCN.

scientific article published on April 2008

Different anthracycline derivates for reducing cardiotoxicity in cancer patients

scientific article (publication date: 12 May 2010)

Different anthracycline derivates for reducing cardiotoxicity in cancer patients

scientific article (published 2010-03-17)

Different anthracycline derivates for reducing cardiotoxicity in cancer patients

scientific article

Different dosage schedules for reducing cardiotoxicity in cancer patients receiving anthracycline chemotherapy

scientific article (published 2009-10-07)

Different dosage schedules for reducing cardiotoxicity in cancer patients receiving anthracycline chemotherapy

scientific article

Direct regulation of the minichromosome maintenance complex by MYCN in neuroblastoma

scientific article published on 10 September 2007

Dose-effect relationships for adverse events after cranial radiation therapy in long-term childhood cancer survivors.

scientific article published on 3 September 2012

Enhancer of zeste homologue 2 plays an important role in neuroblastoma cell survival independent of its histone methyltransferase activity

scientific article published on 16 February 2017

Equivalence Ratio for Daunorubicin to Doxorubicin in Relation to Late Heart Failure in Survivors of Childhood Cancer

scientific article published on 24 August 2015

Evaluation of a patient information website for childhood cancer survivors

scientific article

Evaluation of late adverse events in long-term wilms' tumor survivors

scientific article published on 4 February 2010

Facial asymmetry in head and neck rhabdomyosarcoma survivors.

scientific article

Fenretinide induces mitochondrial ROS and inhibits the mitochondrial respiratory chain in neuroblastoma

scientific article

Gene expression profiling in response to the histone deacetylase inhibitor BL1521 in neuroblastoma

scientific article

Genetic variants inSLC22A17 and SLC22A7are associated with anthracycline-induced cardiotoxicity in children

scientific article published on 31 July 2015

Glomerular function time trends in long-term survivors of childhood cancer: a longitudinal study

scientific article

Health-related quality of life in children and emotional reactions of parents following completion of cancer treatment

scientific article

Hepatic late adverse effects after antineoplastic treatment for childhood cancer

scientific article

Hepatic late adverse effects after treatment for childhood cancer

scientific article

High Hospitalization Rates in Survivors of Childhood Cancer: A Longitudinal Follow-Up Study Using Medical Record Linkage

scientific article

High delta-like 1 expression in a subset of neuroblastoma cell lines corresponds to a differentiated chromaffin cell type

scientific article (publication date: 20 May 2003)

High dose chemotherapy and autologous stem cell rescue for children with high risk neuroblastoma

scientific article

High efficacy of the BCL-2 inhibitor ABT199 (venetoclax) in BCL-2 high-expressing neuroblastoma cell lines and xenografts and rational for combination with MCL-1 inhibition

scientific article published on April 2016

High incidence of malformation syndromes in a series of 1,073 children with cancer.

scientific article

High prevalence of early hypothalamic-pituitary damage in childhood brain tumor survivors: need for standardized follow-up programs

scientific article

High risk of symptomatic cardiac events in childhood cancer survivors

scientific article published on 02 April 2012

High-dose chemotherapy and autologous haematopoietic stem cell rescue for children with high-risk neuroblastoma

scientific article (published 2013-08-22)

High-dose chemotherapy and autologous haematopoietic stem cell rescue for children with high-risk neuroblastoma

scientific article (published 2010-05-12)

Histone deacetylase inhibitor BL1521 induces a G1-phase arrest in neuroblastoma cells through altered expression of cell cycle proteins.

scientific article published on February 2005

Histone deacetylases (HDACs): characterization of the classical HDAC family

scientific article

Identification of BIRC6 as a novel intervention target for neuroblastoma therapy

scientific article

Inactivation of CDK2 is synthetically lethal to MYCN over-expressing cancer cells

scholarly article

Inhibiting Polo-like kinase 1 causes growth reduction and apoptosis in pediatric acute lymphoblastic leukemia cells

scientific article published on 10 June 2013

Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features

scientific article

Iodine-131-meta-iodobenzylguanidine therapy for patients with high-risk neuroblastoma

scientific article

Iodine-131-metaiodobenzylguanidine as initial induction therapy in stage 4 neuroblastoma patients over 1 year of age.

scientific article published on 11 February 2008

Knockdown of survivin (BIRC5) causes apoptosis in neuroblastoma via mitotic catastrophe

scientific article

LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression.

scientific article published on 7 October 2012

Local Resection and Brachytherapy for Primary Orbital Rhabdomyosarcoma: Outcome and Failure Pattern Analysis

scientific article published on 21 September 2015

Longitudinal assessment of health-related quality of life in preschool children with non-CNS cancer after the end of successful treatment

scientific article

MEK inhibition causes Bim stabilization and sensitivity to Bcl2 family member inhibitors in RAS-MAPK mutated neuroblastoma

MIBG scans in patients with stage 4 neuroblastoma reveal two metastatic patterns, one is associated with MYCN amplification and in MYCN-amplified tumours correlates with a better prognosis

scientific article

MIBG scintigraphy and PET imaging for diagnosing neuroblastoma

scientific article (published 2011-09-07)

MON-458 Radiological Alterations Of The Hypothalamic-pituitary Region After Craniospinal Irradiation For Medulloblastoma During Childhood

Malnourished Malawian patients presenting with large Wilms tumours have a decreased vincristine clearance rate

scientific article published on 09 April 2010

Malnutrition and neutropenia in children treated for Burkitt lymphoma in Malawi

scientific article

Management of asymptomatic anthracycline-induced cardiac damage after treatment for childhood cancer: a postal survey among Dutch adult and pediatric cardiologists

scientific article published on 01 June 2005

Mannose-binding lectin (MBL) substitution: recovery of opsonic function in vivo lags behind MBL serum levels

scientific article published on 05 August 2009

Medical assessment of adverse health outcomes in long-term survivors of childhood cancer

scientific article published on 01 June 2007

Medical interventions for treating anthracycline-induced symptomatic and asymptomatic cardiotoxicity during and after treatment for childhood cancer

scientific article (publication date: 7 September 2011)

Medical interventions for treating anthracycline-induced symptomatic and asymptomatic cardiotoxicity during and after treatment for childhood cancer

scientific article (published 2009-10-07)

Meta-analysis of neuroblastomas reveals a skewed ALK mutation spectrum in tumors with MYCN amplification

scientific article published on 18 August 2010

Methylated RASSF1a is the first specific DNA marker for minimal residual disease testing in neuroblastoma.

scientific article published on 5 December 2011

Minimal residual disease detection in autologous stem cell grafts from patients with high risk neuroblastoma.

scientific article

Minimally invasive surgery versus open surgery for the treatment of solid abdominal and thoracic neoplasms in children

scientific article

Minimally invasive surgery versus open surgery for the treatment of solid abdominal and thoracic neoplasms in children

scientific article (publication date: 18 January 2012)

Minimally invasive surgery versus open surgery for the treatment of solid abdominal and thoracic neoplasms in children

scientific article (publication date: 17 March 2010)

Molecular risk stratification of medulloblastoma patients based on immunohistochemical analysis of MYC, LDHB, and CCNB1 expression

scientific article published in July 2008

NF1 is a tumor suppressor in neuroblastoma that determines retinoic acid response and disease outcome

scientific article

Neuroblastoma With Intraspinal Extension: Health Problems in Long-Term Survivors

scientific article

Neuroblastoma messenger RNA is frequently detected in bone marrow at diagnosis of localised neuroblastoma patients

scientific article published on 12 January 2016

Neuroblastoma, maternal valproic acid use, in-vitro fertilization and family history of mosaic chromosome 22: coincidence or causal relationship?

scientific article

Neuroblastoma: biology, prognosis, and treatment

scientific article published on February 2008

Neuroblastoma: biology, prognosis, and treatment

scientific article published on February 2010

Neurofeedback ineffective in paediatric brain tumour survivors: Results of a double-blind randomised placebo-controlled trial.

scientific article published on 22 June 2016

Newly-derived neuroblastoma cell lines propagated in serum-free media recapitulate the genotype and phenotype of primary neuroblastoma tumours

scientific article published on 6 December 2013

Nutritional status at admission of children with cancer in Malawi

scientific article published in November 2008

Obituary of a very special doctor, Dr Jan de Kraker (October 18, 1944 to January 19, 2012).

scientific article

PHOX2B is a novel and specific marker for minimal residual disease testing in neuroblastoma

scientific article published on 6 October 2008

Peripheral stem cell apheresis is feasible post Iodine-metaiodobenzylguanidine- therapy in high-risk neuroblastoma, but results in delayed platelet reconstitution

scientific article published on 12 October 2018

Pharmacogenomic Prediction of Anthracycline-Induced Cardiotoxicity in Children

Pleiotropic effects of fenretinide in neuroblastoma cell lines and multicellular tumor spheroids.

scientific article

Polo-Like Kinase 1 (PLK1) Inhibition Reduces Cell Proliferation and Induces Apoptosis in Childhood Acute Lymphoblastic Leukemia ⬇️

scholarly article

Preoperative chemotherapy for patients with Wilms tumor in Malawi is feasible and efficacious

scientific article

Prevalence and patterns of morphological abnormalities in patients with childhood cancer

scientific article

Prevalence and risk factors of radiation-induced growth hormone deficiency in childhood cancer survivors: a systematic review

scientific article published on 28 July 2009

Prevalence of congenital heart defects in neuroblastoma patients: a cohort study and systematic review of literature.

scientific article published on 17 December 2008

Prevalence of rib anomalies in normal Caucasian children and childhood cancer patients

scientific article published on 12 February 2005

Prevention of anthracycline-induced cardiotoxicity in children: the evidence

scientific article published on 26 March 2007

Prevention of central venous catheter-associated bloodstream infections in paediatric oncology patients using 70% ethanol locks: A randomised controlled multi-centre trial

scientific article published on 15 July 2015

Prognostic factors for progression of childhood optic pathway glioma: a systematic review

scientific article published on 30 June 2006

Promising effects of the 4HPR-BSO combination in neuroblastoma monolayers and spheroids

scientific article published on 23 June 2011

Psychosocial indicators of health-related quality of life in children with cancer 2 months after end of successful treatment

scientific article published in August 2007

Psychosocial well-being of long-term survivors of pediatric head-neck rhabdomyosarcoma

article

Pulmonary function impairment measured by pulmonary function tests in long-term survivors of childhood cancer

scientific article published on 29 July 2011

QOS-48PREVALENCE AND RISK FACTORS OF EARLY ENDOCRINE DISORDERS IN CHILDHOOD BRAIN TUMOR SURVIVORS: A NATIONWIDE MULTICENTER STUDY.

scientific article

Real-world implementation of electronic patient-reported outcomes in outpatient pediatric cancer care

scientific article published on 8 August 2016

Rearrangements and increased expression of cyclin D1 (CCND1) in neuroblastoma

scientific article published on 01 March 2003

Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations

scientific article published on 29 June 2015

Renal dysfunction and elevated blood pressure in long-term childhood cancer survivors

scientific article

Reporting health‐related quality of life scores to physicians during routine follow‐up visits of pediatric oncology patients: Is it effective? ⬇️

scientific article published on May 16, 2011

Response assessment in pediatric rhabdomyosarcoma: can response evaluation criteria in solid tumors replace three-dimensional volume assessments?

scientific article

Response to "cancer care in the pediatric surgical patient: a paradigm to abolish volume-outcome disparities in surgery".

scientific article published on 20 September 2009

Retinoic acid reduces the cytotoxicity of cyclopentenyl cytosine in neuroblastoma cells

scientific article published in September 2002

Risk of Symptomatic Stroke After Radiation Therapy for Childhood Cancer: A Long-Term Follow-Up Cohort Analysis

scientific article published on 8 April 2016

Safety and pharmacokinetics of plasma-derived mannose-binding lectin (MBL) substitution in children with chemotherapy-induced neutropaenia

scientific article published on 31 December 2008

Screening for Psychosocial Risk in Dutch Families of a Child With Cancer: Reliability, Validity, and Usability of the Psychosocial Assessment Tool

scientific article published on 29 December 2015

Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes

scientific article

Should anthracyclines and dexrazoxane be used for children with cancer?

scientific article published on 01 January 2011

Social outcomes in adult survivors of childhood cancer compared to the general population: linkage of a cohort with population registers

scientific article published on 23 November 2015

Stability of PCR targets for monitoring minimal residual disease in neuroblastoma.

scientific article published on 16 January 2012

Structural genome variations in individuals with childhood cancer and tumour predisposition syndromes

scientific article published on 6 March 2013

Studying Hospitalizations and Mortality in the Netherlands: Feasible and Valid Using Two-Step Medical Record Linkage with Nationwide Registers

scientific article published on 6 July 2015

Surveillance of hepatic late adverse effects in a large cohort of long-term survivors of childhood cancer: prevalence and risk factors

scientific article published on 15 August 2012

Synergistic interaction between cisplatin and gemcitabine in neuroblastoma cell lines and multicellular tumor spheroids

scientific article

Targeted BCL2 inhibition effectively inhibits neuroblastoma tumour growth

scientific article

Targeted BIRC5 silencing using YM155 causes cell death in neuroblastoma cells with low ABCB1 expression

scientific article

The High Prevalence of Functional Complement Defects Induced by Chemotherapy

scientific article published on 17 October 2016

The N-myc and c-myc downstream pathways include the chromosome 17q genes nm23-H1 and nm23-H2.

scientific article

The Phox2B homeobox gene is mutated in sporadic neuroblastomas

scientific article

The Potential of Aurora Kinases A and B As Therapeutic Targets in Pediatric Acute Leukemia ⬇️

scholarly article

The development of a clinical screening instrument for tumour predisposition syndromes in childhood cancer patients

scientific article

The efficacy and toxicity of SIOP preoperative chemotherapy in Malawian children with a Wilms tumour

scientific article published on 23 January 2012

The guardians' perspective on paediatric cancer treatment in Malawi and factors affecting adherence

scientific article published in November 2008

The human transcriptome map reveals extremes in gene density, intron length, GC content, and repeat pattern for domains of highly and weakly expressed genes

scientific article

The influence of patient reported outcomes on the discussion of psychosocial issues in children with cancer ⬇️

scientific article published on January 23, 2012

The novel histone deacetylase inhibitor BL1521 inhibits proliferation and induces apoptosis in neuroblastoma cells.

scientific article published in October 2004

The polyamine metabolism genes ornithine decarboxylase and antizyme 2 predict aggressive behavior in neuroblastomas with and without MYCN amplification

scientific article

The role of 131I-metaiodobenzylguanidine (MIBG) therapy in unresectable and compromising localised neuroblastoma

scientific article published on 06 June 2013

The role of the 'innovative therapies for children with cancer' (ITCC) European consortium.

scientific article published on 15 March 2010

The use of equivalent radiation dose in the evaluation of late effects after childhood cancer treatment.

scientific article published on 14 June 2014

Towards personalized therapy in pediatric acute lymphoblastic leukemia: RAS mutations and prednisolone resistance

scientific article published on 5 December 2014

Toxicity of upfront ¹³¹I-metaiodobenzylguanidine (¹³¹I-MIBG) therapy in newly diagnosed neuroblastoma patients: a retrospective analysis

scientific article

Treatment and outcome of neuroblastoma with intraspinal extension: A systematic review

scientific article published on 2 February 2017

Treatment including anthracyclines versus treatment not including anthracyclines for childhood cancer

scientific article

Treatment including anthracyclines versus treatment not including anthracyclines for childhood cancer

scientific article (published 2011-01-19)

Treatment including anthracyclines versus treatment not including anthracyclines for childhood cancer

scientific article (published 2009-01-21)

Upfront treatment of high-risk neuroblastoma with a combination of 131I-MIBG and topotecan

scientific article published on 15 May 2015

Validated assay for the simultaneous quantification of total vincristine and actinomycin-D concentrations in human EDTA plasma and of vincristine concentrations in human plasma ultrafiltrate by high-performance liquid chromatography coupled with tan

scientific article

Valvular abnormalities detected by echocardiography in 5-year survivors of childhood cancer: a long-term follow-up study

scientific article published on 25 October 2014

Whole-Genome Sequencing Identifies Patient-Specific DNA Minimal Residual Disease Markers in Neuroblastoma

scholarly article by Esther M. van Wezel et al published January 2015 in The Journal of Molecular Diagnostics

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