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List of works by Luc Cynober

"Immunonutrition" Has Failed to Improve Peritonitis-Induced Septic Shock in Rodents

scientific article published on 25 January 2016

7e symposium « Biologie d'urgence et gaz du sang »

scientific article published on 01 October 2018

An Oligomeric Diet Limits the Response to Injury in Traumatic Brain-Injured Rats ⬇️

scientific article published on June 6, 2013

Analytical evaluation of a high-sensitivity troponin T assay and its clinical assessment in acute coronary syndrome

scientific article published on 22 June 2011

Aortic banding in rat as a model to investigate malnutrition associated with heart failure

scientific article published on 6 January 2005

Arginine administration to critically ill patients with a low nitric oxide fraction in the airways: a pilot study

scientific article published on 19 June 2013

Arginine and glutamine availability and macrophage functions in the obese insulin-resistant Zucker rat.

scientific article published in January 2005

Arginine availability modulates arginine metabolism and TNFα production in peritoneal macrophages from Zucker Diabetic Fatty rats

scientific article published on 17 December 2011

Arginine does not exacerbate markers of inflammation in cocultures of human enterocytes and leukocytes.

scientific article published in January 2007

Arginine or citrulline associated with a statin stimulates nitric oxide production in bovine aortic endothelial cells

Arginine reduces bacterial invasion in rats with head injury: an in vivo evaluation by bioluminescence.

scientific article

Arginine-enriched diet limits plasma and muscle glutamine depletion in head-injured rats

scientific article published on 02 August 2006

Arginine-supplemented enteral nutrition in critically ill diabetic and obese rats: a dose-ranging study evaluating nutritional status and macrophage function

scientific article published on 22 October 2012

Assessment of transthyretin cut-off values for a better screening of malnutrition: Retrospective determination and prospective validation

scientific article published on 25 June 2020

Behaviour of plasma citrulline after bariatric surgery in the BARIASPERM cohort

scientific article published on 12 June 2020

Best temperature for static liver graft storage is 1°C ⬇️

scientific article published on May 12, 2012

Characterization of the alteration of nutritional state in brain injury induced by fluid percussion in rats.

scientific article published on 30 November 2004

Citrulline and the gut.

scientific article published on September 2007

Citrulline as a biomarker of intestinal failure due to enterocyte mass reduction.

scientific article published on 28 April 2008

Citrulline directly modulates muscle protein synthesis via the PI3K/MAPK/4E-BP1 pathway in a malnourished state: evidence from in vivo, ex vivo, and in vitro studies

scientific article published on 8 November 2016

Citrulline enhances myofibrillar constituents expression of skeletal muscle and induces a switch in muscle energy metabolism in malnourished aged rats

scientific article published on 10 June 2013

Citrulline prevents age-related LTP decline in old rats

scientific article published on 27 December 2019

Citrulline stimulates locomotor activity in aged rats: Implication of the dopaminergic pathway

scientific article published on 9 January 2017

Citrulline stimulates muscle protein synthesis in the post-absorptive state in healthy people fed a low-protein diet - A pilot study

scientific article

Citrulline: a new player in the control of nitrogen homeostasis

scientific article published on June 2007

Citrulline: from metabolism to therapeutic use.

scientific article published on 28 September 2012

Combining citrulline with atorvastatin preserves glucose homeostasis in a murine model of diet-induced obesity

scientific article published on 30 July 2015

Consequences of head injury and static cold storage on hepatic function: ex vivo experiments using a model of isolated perfused rat liver.

scientific article published on 16 July 2009

Creatinine-to-cystatin C ratio and bioelectrical impedance analysis for the assessement of low lean body mass in cancer patients: Comparison to L3-computed tomography scan

scientific article published on 15 June 2020

Decreased glutamate, glutamine and citrulline concentrations in plasma and muscle in endotoxemia cannot be reversed by glutamate or glutamine supplementation: a primary intestinal defect?

scientific article published on 01 October 2012

Does the ornithine-alpha-ketoglutarate ratio influence ornithine alpha-ketoglutarate metabolism in healthy rats?

scientific article published in January 2007

Dose dependency of the effect of ornithine alpha-ketoglutarate on tissue glutamine concentrations and hypercatabolic response in endotoxaemic rats

scientific article published in October 2004

Early Expansion of Circulating Granulocytic Myeloid-derived Suppressor Cells Predicts Development of Nosocomial Infections in Patients with Sepsis

scientific article published on February 2017

Effect of aging on liver functions-an experimental study in a perfused rat liver model

scientific article published in September 2004

Effect of an immune-enhancing diet on lymphocyte in head-injured rats: what is the role of arginine?

scientific article published on 11 April 2007

Effect of citrulline on muscle protein turnover in an in vitro model of muscle catabolism

scientific article published on 20 September 2019

Effect of intestinal resections on arginine metabolism: practical implications for nutrition support.

scientific article published on January 2010

Effect of specific amino acids on hepatic lipid metabolism in fructose-induced non-alcoholic fatty liver disease

scientific article published on 11 February 2015

Effects of a Carbohydrate-, Glutamine-, and Antioxidant-Enriched Oral Nutrition Supplement on Major Surgery-Induced Insulin Resistance: A Randomized Pilot Study

scientific article

Effects of a diabetes-specific enteral nutrition on nutritional and immune status of diabetic, obese, and endotoxemic rats: interest of a graded arginine supply.

scientific article published in August 2012

Effects of leucine and citrulline versus non-essential amino acids on muscle protein synthesis in fasted rat: a common activation pathway? ⬇️

scientific article published on December 13, 2011

Effects of ornithine alpha-ketoglutarate on insulin secretion in rat pancreatic islets: implication of nitric oxide synthase and glutamine synthetase pathways

scientific journal article

Effects of ornithine alpha-ketoglutarate on protein metabolism in Yoshida sarcoma-bearing rats

scientific article published on 25 June 2007

Endotoxemia affects citrulline, arginine and glutamine bioavailability

scientific article published on 23 August 2011

Evaluation of a glycine-rich amino acid solution for parenteral nutrition in endotoxemic rats

scientific article

Evaluation of a new concept of immune-enhancing diet in a model of head-injured rat with infectious complications: A proof of concept study.

scientific article published on 24 April 2016

Evidence for impairment of hepatic energy homeostasis in head-injured rat.

scientific article published in February 2008

Evidence that albumin is not a suitable marker of body composition-related nutritional status in elderly patients

scientific article published on 24 April 2010

Evidence that glutamine modulates respiratory burst in stressed rat polymorphonuclear cells through its metabolism into arginine

scientific article

Fat mass protects hospitalized elderly persons against morbidity and mortality

scientific article published on 29 July 2009

French Intensive Care Society, International congress - Réanimation 2016

scientific article published in June 2016

Geriatric Nutritional Risk Index: a new index for evaluating at-risk elderly medical patients

scientific article

Glutamine in the intensive care unit

scientific article published on January 2014

Growth hormone enhances fat-free mass and glutamine availability in patients with short-bowel syndrome: an ancillary double-blind, randomized crossover study.

scientific article published on 30 July 2014

Head injury profoundly affects gut microbiota homeostasis: Results of a pilot study

scientific article published on 8 July 2017

High plasma citrulline and arginine levels ensured by sustained-release citrulline supplementation in rats

scientific article published on 09 April 2011

Hypermetabolism is an independent prognostic factor of survival in metastatic non-small cell lung cancer patients

scientific article published on 10 August 2019

If the soup tastes bad, it doesn’t mean the potatoes are the culprit ⬇️

scientific article published on 01 August 2012

Impact of protein pulse feeding on lean mass in malnourished and at-risk hospitalized elderly patients: a randomized controlled trial

scientific article

Impact of qualitative and quantitative variations in nitrogen supply on catch-up growth in food-deprived-refed young rats

scientific article

Impairment of lymphocyte function in head-injured rats: effects of standard and immune-enhancing diets for enteral nutrition.

scientific article

In VivoBioluminescent Imaging of a New Model of Infectious Complications in Head-Injury Rats ⬇️

scientific article published on October 24, 2011

In vitro anti-inflammatory effects of citrulline on peritoneal macrophages in Zucker diabetic fatty rats

scientific article published on 13 November 2014

In vivo induction of insulin secretion by ornithine alpha-ketoglutarate: involvement of nitric oxide and glutamine

scientific article published in March 2003

Increasing plasma glutamine in postoperative patients fed an arginine-rich immune-enhancing diet--a pharmacokinetic randomized controlled study

scientific article

Indications and contraindications for infusing specific amino acids (leucine, glutamine, arginine, citrulline, and taurine) in critical illness

scientific article published on 28 January 2016

Influence of an ω3-fatty acid-enriched enteral diet with and without added glutamine on the metabolic response to injury in a rat model of prolonged acute catabolism

scientific article published on 13 June 2017

Interactions between ω3 polyunsaturated fatty acids and arginine on nutritional and immunological aspects in severe inflammation

scientific article published on 13 April 2010

Isolated perfused liver model: the rat and guinea pig compared

scientific article published in May 2004

L-alanyl-L-glutamine dipeptide-supplemented total parenteral nutrition reduces infectious complications and glucose intolerance in critically ill patients: the French controlled, randomized, double-blind, multicenter study

scientific article published in March 2006

L-arginine plus atorvastatin for prevention of atheroma formation in genetically hypercholesterolaemic rabbits

scientific article published on 29 March 2007

Lean Body Mass and Endocrine Status But Not Age Are Determinants of Resting Energy Expenditure in Patients with Non-Small Cell Lung Cancer

scientific article published on 19 December 2019

Leucine and Citrulline: Two Major Regulators of Protein Turnover ⬇️

scientific article published on October 12, 2012

Leucine and citrulline modulate muscle function in malnourished aged rats ⬇️

scientific article published on February 23, 2011

Long-lasting improved amino acid bioavailability associated with protein pulse feeding in hospitalized elderly patients: a randomized controlled trial.

scientific article

Mechanisms and kinetics of citrulline uptake in a model of human intestinal epithelial cells

scientific article published in October 2008

Metabolic response and nutritional support in traumatic brain injury: evidence for resistance to renutrition

scientific article published in November 2009

Midregional Pro–Atrial Natriuretic Peptide for the Diagnosis of Cardiac-Related Dyspnea according to Renal Function in the Emergency Department: A Comparison with B-Type Natriuretic Peptide (BNP) and N-Terminal ProBNP ⬇️

scientific article published on 02 September 2010

Nitric oxide production by peritoneal macrophages from aged rats: A short term and direct modulation by citrulline

scientific article published on 7 December 2016

Ornithine Aminotransferase, an Important Glutamate-Metabolizing Enzyme at the Crossroads of Multiple Metabolic Pathways

scientific article published on 07 March 2017

Ornithine alpha-ketoglutarate metabolism in the healthy rat in the postabsorptive state

scientific article published in August 2005

Ornithine alpha-ketoglutarate supplementation influences motor activity in healthy rats

scientific article published on August 2004

Overexpression of ornithine aminotransferase: consequences on amino acid homeostasis.

scientific article

Performance of glycogen phosphorylase isoenzyme BB is weak in the detection of patients with non-ST-elevation acute coronary syndrome

scientific article published on 28 July 2011

Plasma L-citrulline concentrations and its relationship with inflammation at the onset of septic shock: a pilot study

scientific article published on 26 November 2013

Plasma citrulline is a biomarker of enterocyte mass and an indicator of parenteral nutrition in HIV-infected patients

scientific article published on 08 July 2009

Plasma citrulline: a marker of enterocyte mass in villous atrophy-associated small bowel disease ⬇️

scientific article published on May 1, 2003

Polyamines: metabolism and implications in human diseases

scientific article

Pretreatment of starved rats with ornithine alpha-ketoglutarate: effects on hepatic mRNA levels and plasma concentrations of three liver-secreted proteins.

scientific article published in June 2005

Protective effects of regulatory amino acids on ischemia-reperfusion injury in the isolated perfused rat liver

scientific article published in November 2006

Sex-differential expression of ornithine aminotransferase in the mouse kidney.

scientific article published in March 2007

Taurine status and response to intravenous taurine supplementation in adults with short-bowel syndrome undergoing long-term parenteral nutrition: a pilot study

scientific article published on 01 August 2006

The 2009 ESPEN Sir David Cuthbertson. Citrulline: a new major signaling molecule or just another player in the pharmaconutrition game?

scientific article published on 16 August 2010

The feeding route (enteral or parenteral) affects the plasma response of the dipetide Ala-Gln and the amino acids glutamine, citrulline and arginine, with the administration of Ala-Gln in preoperative patients

scientific article

Therapeutic use of branched-chain amino acids in burn, trauma, and sepsis

scientific article

Tolerance and efficacy of a new enteral formula specifically designed for elderly persons: an experimental study in the aged rat.

scientific article published in July 2008

Transthyretin for the routine assessment of malnutrition: A clinical dilemma highlighted by an international survey of experts in the field

scientific article published on 25 September 2018

[Circulating citrulline levels: a biomarker for intestinal functionality assessment]

scientific article published on 01 September 2011

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