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List of works by Hans Langendijk

"Radiobiology of Proton Therapy": Results of an international expert workshop

scientific article published on 01 June 2018

18F-FDG PET during stereotactic body radiotherapy for stage I lung tumours cannot predict outcome: a pilot study

scientific article

18F-FDG PET image biomarkers improve prediction of late radiation-induced xerostomia

scientific article published on 23 September 2017

18F-FLT-PET for detection of rectal cancer

scientific article published on 03 February 2011

2-Deoxy-2[F-18]FDG-PET for detection of recurrent laryngeal carcinoma after radiotherapy: interobserver variability in reporting

scientific article published on 12 July 2008

3D Variation in delineation of head and neck organs at risk

scientific article published on 13 March 2012

A Clarion Call for Large-Scale Collaborative Studies of Pediatric Proton Therapy

scientific article published on 10 July 2017

A Model-Based Approach to Predict Short-Term Toxicity Benefits With Proton Therapy for Oropharyngeal Cancer

scientific article published on 6 January 2019

A comparison of weekly versus 3-weekly cisplatin during adjuvant radiotherapy for high-risk head and neck cancer.

scientific article published on August 2016

A comprehensive motion analysis - consequences for high precision image-guided radiotherapy of esophageal cancer patients

scientific article published on 05 November 2020

A new CT-based method to quantify radiation-induced lung damage in patients

scientific article published on 04 August 2015

A phase II study of primary reirradiation in squamous cell carcinoma of head and neck.

scientific article published on 9 March 2006

A predictive model for swallowing dysfunction after curative radiotherapy in head and neck cancer

scientific article published on 21 January 2009

A prospective cohort study on radiation-induced hypothyroidism: development of an NTCP model

scientific article published on 19 June 2012

A review on re-irradiation for recurrent and second primary head and neck cancer

scientific article

A screening questionnaire for voice problems after treatment of early glottic cancer

scientific article published in July 2005

A systematic review on the role of FDG-PET/CT in tumour delineation and radiotherapy planning in patients with esophageal cancer

scientific article

ACE inhibition attenuates radiation-induced cardiopulmonary damage.

scientific article published on 25 November 2014

Acute skin toxicity management in head and neck cancer patients treated with radiotherapy and chemotherapy or EGFR inhibitors: Literature review and consensus

scientific article published on 02 July 2015

Acute symptoms during the course of head and neck radiotherapy or chemoradiation are strong predictors of late dysphagia

scientific article published on 16 March 2015

Advances in Radiotherapy for Head and Neck Cancer

scientific article published on 08 September 2015

Advancing interdisciplinary research in head and neck cancer through a multicenter longitudinal prospective cohort study: the NETherlands QUality of life and BIomedical Cohort (NET-QUBIC) data warehouse and biobank

scientific article published on 05 August 2019

Age-specific incidence and treatment patterns of head and neck cancer in the Netherlands-A cohort study.

scientific article published on 26 September 2017

Amplicon mapping and expression profiling identify the Fas-associated death domain gene as a new driver in the 11q13.3 amplicon in laryngeal/pharyngeal cancer

scientific article published in November 2007

An automated, quantitative, and case-specific evaluation of deformable image registration in computed tomography images

scientific article

An in silico comparison between margin-based and probabilistic target-planning approaches in head and neck cancer patients.

scientific article published on 14 September 2013

An instrument dedicated for modelling of pulmonary radiotherapy

scientific article published on 9 April 2015

Analysis of the applicability of two-dimensional detector arrays in terms of sampling rate and detector size to verify scanned intensity modulated proton therapy plans

scientific article published on 23 June 2020

Artificial neural network analysis to assess hypernasality in patients treated for oral or oropharyngeal cancer

scientific article published on 24 August 2011

Assessing and improving quality of life in patients with head and neck cancer

scientific article

Assessment of Neurocognitive Impairment and Speech Functioning Before Head and Neck Cancer Treatment

scientific article published on 01 March 2019

Assessment of dosimetric errors induced by deformable image registration methods in 4D pencil beam scanned proton treatment planning for liver tumours

scientific article published on 20 March 2018

Assessment of hypoxic subvolumes in laryngeal cancer with (18)F-fluoroazomycinarabinoside ((18)F-FAZA)-PET/CT scanning and immunohistochemistry

scientific article published on 3 August 2015

Assessment of range uncertainty in lung-like tissue using a porcine lung phantom and proton radiography

scientific article published on 11 May 2020

Associations between voice quality and swallowing function in patients treated for oral or oropharyngeal cancer.

scientific article published on 24 February 2013

Automated Robust Proton Planning Using Dose-Volume Histogram-Based Mimicking of the Photon Reference Dose and Reducing Organ at Risk Dose Optimization

scientific article published on 24 August 2018

Bath and shower effects in the rat parotid gland explain increased relative risk of parotid gland dysfunction after intensity-modulated radiotherapy

scientific article published on 01 July 2009

Biological mechanisms of normal tissue damage: importance for the design of NTCP models

scientific article published on 29 June 2012

Biological tumor markers associated with local control after primary radiotherapy in laryngeal cancer: a systematic review

scientific article published on 04 April 2020

Brain abnormalities on MRI in non-functioning pituitary adenoma patients treated with or without postoperative radiotherapy.

scientific article published on 14 January 2015

CT image biomarkers to improve patient-specific prediction of radiation-induced xerostomia and sticky saliva

scientific article published on 22 July 2016

CT-based delineation of organs at risk in the head and neck region: DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines.

scientific article published on 13 August 2015

Can we safely reduce the radiation dose to the heart while compromising the dose to the lungs in oesophageal cancer patients?

scientific article published on 20 May 2020

Cardiac Function After Radiation Therapy for Breast Cancer

scientific article published on 11 February 2019

Cardiac toxicity in the radiation treatment of esophageal cancer: an emerging concern

scientific article

Cardiovascular morbidity after radiotherapy or chemoradiation in patients with cervical cancer

scientific article published on 29 March 2010

Carotid body paragangliomas: a systematic study on management with surgery and radiotherapy.

scientific article

Changes in nutritional status and dietary intake during and after head and neck cancer treatment

scientific article published on 24 August 2010

Chemoradiotherapy vs. total laryngectomy for primary treatment of advanced laryngeal squamous cell carcinoma

scientific article

Circulating invariant natural killer T-cell numbers predict outcome in head and neck squamous cell carcinoma: updated analysis with 10-year follow-up

scientific article published on 17 January 2012

Clinical Trial Strategies to Compare Protons With Photons

scientific article published on 01 April 2018

Clinical introduction of a linac head-mounted 2D detector array based quality assurance system in head and neck IMRT

scientific article published on 29 September 2011

Clinical management of salivary gland hypofunction and xerostomia in head-and-neck cancer patients: successes and barriers.

scientific article

Clinical validation of FDG-PET/CT in the radiation treatment planning for patients with oesophageal cancer

scientific article published on 29 November 2014

Co-morbidity and treatment outcomes of elderly pharyngeal cancer patients: a matched control study

scientific article published on 31 August 2011

Comparison of CBCT based synthetic CT methods suitable for proton dose calculations in adaptive proton therapy

scientific article published on 06 March 2020

Comparison of Carboplatin With 5-Fluorouracil vs. Cisplatin as Concomitant Chemoradiotherapy for Locally Advanced Head and Neck Squamous Cell Carcinoma

scientific article published on 05 June 2020

Comparison of acute and subacute genitourinary and gastrointestinal adverse events of radiotherapy for prostate cancer using intensity-modulated radiation therapy, three-dimensional conformal radiation therapy, permanent implant brachytherapy and hi

scientific article published on 01 May 2014

Comparison of normal tissue dose with three-dimensional conformal techniques for breast cancer irradiation including the internal mammary nodes

scientific article published on 05 July 2005

Compliance and efficiency before and after implementation of a clinical practice guideline for laryngeal carcinomas

scientific article published on 14 May 2006

Composite minimax robust optimization of VMAT improves target coverage and reduces non-target dose in head and neck cancer patients

scientific article published on 11 April 2019

Comprehensive 4D robustness evaluation for pencil beam scanned proton plans

scientific article published on 20 April 2019

Computerized monitoring of patient-reported speech and swallowing problems in head and neck cancer patients in clinical practice.

scientific article

Conducting radiogenomic research--do not forget careful consideration of the clinical data

scientific article

Consequences of additional use of PET information for target volume delineation and radiotherapy dose distribution for esophageal cancer

scientific article published on 16 September 2009

Contemporary management of lymph node metastases from an unknown primary to the neck: I. A review of diagnostic approaches.

scientific article published on 27 October 2011

Contemporary management of lymph node metastases from an unknown primary to the neck: II. a review of therapeutic options

scientific article published on 27 October 2011

Contemporary management of sinonasal cancer

scientific article published on 24 August 2010

Control of nodal metastases in squamous cell head and neck cancer treated by radiation therapy or chemoradiation

scientific article published on 01 April 2006

Cordectomy by CO2 laser or radiotherapy for small T1a glottic carcinomas: costs, local control, survival, quality of life, and voice quality

scientific article published in February 2007

Correction to: Advancing interdisciplinary research in head and neck cancer through a multicenter longitudinal prospective cohort study: the NETherlands QUality of life and BIomedical Cohort (NET-QUBIC) data warehouse and biobank

scientific article published on 22 October 2019

Creating a data exchange strategy for radiotherapy research: towards federated databases and anonymised public datasets

scientific article

Critical weight loss is a major prognostic indicator for disease-specific survival in patients with head and neck cancer receiving radiotherapy

scientific article published on 08 August 2013

Cumulative cisplatin dose in concurrent chemoradiotherapy for head and neck cancer: A systematic review.

scientific article

Current ideas to reduce or salvage radiation damage to salivary glands

scientific article published on 28 February 2014

Current management of stage IV nasopharyngeal carcinoma without distant metastasis

scientific article published on 21 February 2020

Current treatment options for recurrent nasopharyngeal cancer.

scientific article published on 24 September 2010

Current trends in initial management of hypopharyngeal cancer: the declining use of open surgery

scientific article

Decreasing Irradiated Rat Lung Volume Changes Dose-Limiting Toxicity From Early to Late Effects

scientific article published on 28 September 2015

Deformable image registration uncertainty for inter-fractional dose accumulation of lung cancer proton therapy

scientific article published on 04 May 2020

Delayed Effects of a Single Dose Whole-Brain Radiation Therapy on Glucose Metabolism and Myelin Density: a Longitudinal PET Study

scientific article published on 30 June 2020

Delineation guidelines for organs at risk involved in radiation-induced salivary dysfunction and xerostomia

scientific article published on 21 October 2009

Delineation of organs at risk involved in swallowing for radiotherapy treatment planning

scientific article published on 12 June 2011

Delineation of the neck node levels for head and neck tumors: a 2013 update. DAHANCA, EORTC, HKNPCSG, NCIC CTG, NCRI, RTOG, TROG consensus guidelines.

scientific article published on 31 October 2013

Delta-radiomics features during radiotherapy improve the prediction of late xerostomia

scientific article published on 28 August 2019

Demographic, clinical and lifestyle-related correlates of accelerometer assessed physical activity and fitness in newly diagnosed patients with head and neck cancer

scientific article published on 12 October 2019

Design of and technical challenges involved in a framework for multicentric radiotherapy treatment planning studies.

scientific article

Detecting recurrent laryngeal carcinoma after radiotherapy: room for improvement

scientific article published on 19 November 2003

Development and evaluation of an auto-segmentation tool for the left anterior descending coronary artery of breast cancer patients based on anatomical landmarks

scientific article published on 04 April 2019

Development and evaluation of an online three-level proton vs photon decision support prototype for head and neck cancer - Comparison of dose, toxicity and cost-effectiveness.

scientific article

Development and validation of a prediction model for tube feeding dependence after curative (chemo-) radiation in head and neck cancer

scientific article

Development of NTCP models for head and neck cancer patients treated with three-dimensional conformal radiotherapy for xerostomia and sticky saliva: The role of dosimetric and clinical factors

article

Development of Normal Tissue Complication Probability Model for Trismus in Head and Neck Cancer Patients Treated With Radiotherapy: The Role of Dosimetric and Clinical Factors

scientific article published on 01 December 2019

Development of a facility for high-precision irradiation of cells with carbon ions

scientific article published on 01 January 2011

Development of a multivariable normal tissue complication probability (NTCP) model for tube feeding dependence after curative radiotherapy/chemo-radiotherapy in head and neck cancer

scientific article published on 16 October 2014

Development of a prediction model for late urinary incontinence, hematuria, pain and voiding frequency among irradiated prostate cancer patients

scientific article published on 17 July 2018

Development of an iterative reconstruction method to overcome 2D detector low resolution limitations in MLC leaf position error detection for 3D dose verification in IMRT.

scientific article published on 21 April 2016

Differences in delineation guidelines for head and neck cancer result in inconsistent reported dose and corresponding NTCP

scientific article published on 20 February 2014

Direct use of multivariable normal tissue complication probability models in treatment plan optimisation for individualised head and neck cancer radiotherapy produces clinically acceptable treatment plans

scientific article published on 11 September 2014

Distant metastases from head and neck squamous cell carcinoma. Part III. Treatment

scientific article published on 18 April 2012

Distant metastases in head and neck carcinoma: identification of prognostic groups with MR imaging

scientific article published on 10 July 2006

Do patients trust their physician? The role of attachment style in the patient-physician relationship within one year after a cancer diagnosis ⬇️

scientific article published on November 1, 2012

Does hyperbaric oxygen therapy improve quality of life?

scientific article published on 27 December 2008

Does radiation dose to the salivary glands and oral cavity predict patient-rated xerostomia and sticky saliva in head and neck cancer patients treated with curative radiotherapy?

scientific article published on 26 October 2005

Does screening for distress efficiently uncover meetable unmet needs in cancer patients? ⬇️

scientific article published on March 6, 2011

Dose-volume-response analysis in stereotactic radiotherapy for early lung cancer

scientific article published on 5 August 2014

Dosimetric consequences of the shift towards computed tomography guided target definition and planning for breast conserving radiotherapy

scientific article published on 31 January 2008

Dynamics of tumor hypoxia assessed by 18F-FAZA PET/CT in head and neck and lung cancer patients during chemoradiation: possible implications for radiotherapy treatment planning strategies

scientific article published on 27 November 2014

Dysphagia in head and neck cancer patients treated with radiotherapy and systemic therapies: Literature review and consensus

scientific article published on 19 June 2015

EORTC 24051: Unexpected side effects in a phase I study of TPF induction chemotherapy followed by chemoradiation with lapatinib, a dual EGFR/ErbB2 inhibitor, in patients with locally advanced resectable larynx and hypopharynx squamous cell carcinoma

scientific article published in November 2012

Early Detection of Cardiovascular Changes After Radiotherapy for Breast Cancer: Protocol for a European Multicenter Prospective Cohort Study (MEDIRAD EARLY HEART Study)

scientific article published on 01 October 2018

Early detection of cardiovascular changes after radiotherapy for breast cancer: Protocol for a European multicenter prospective cohort (MEDIRAD EARLY HEART Study) (Preprint)

Early-stage young breast cancer patients: impact of local treatment on survival

scientific article published on 09 September 2011

Effect of amifostine on survival among patients treated with radiotherapy: a meta-analysis of individual patient data

scientific article

Efficacy of routine pre-radiation dental screening and dental follow-up in head and neck oncology patients on intermediate and late radiation effects. A retrospective evaluation

scientific article published on 14 October 2011

Efficient and reliable 3D dose quality assurance for IMRT by combining independent dose calculations with measurements.

scientific article

Electronic portal images (EPIs) based position verification for the breast simultaneous integrated boost (SIB) technique

scientific article published on 16 November 2011

Enhanced proliferation of acinar and progenitor cells by prophylactic pilocarpine treatment underlies the observed amelioration of radiation injury to parotid glands.

scientific article published on 10 January 2009

Evaluating adherence to the Dutch guideline for diagnosis, treatment and follow-up of laryngeal carcinomas

scientific article published in March 2005

Evaluation of DVH-based treatment plan verification in addition to gamma passing rates for head and neck IMRT

scientific article published on 22 August 2014

Evaluation of a 3D surface imaging system for deep inspiration breath-hold patient positioning and intra-fraction monitoring

scientific article published on 11 July 2019

Evaluation of the impact of tumor HPV status on outcome in patients with locally advanced unresectable head and neck squamous cell carcinoma (HNSCC) receiving cisplatin, 5-fluorouracil with or without docetaxel: A subset analysis of EORTC 24971 stud

scientific article

Evidence-based review of treatment options for patients with glottic cancer

scientific article

External beam radiotherapy combined with intraluminal brachytherapy in esophageal carcinoma

scientific article published on 30 August 2011

External validation of a multifactorial normal tissue complication probability model for tube feeding dependence at 6 months after definitive radiotherapy for head and neck cancer

scientific article published on 06 October 2018

External validation of a risk group defined by recursive partitioning analysis in patients with head and neck carcinoma treated with surgery and postoperative radiotherapy

scientific article

External validation of three dimensional conformal radiotherapy based NTCP models for patient-rated xerostomia and sticky saliva among patients treated with intensity modulated radiotherapy

scientific article published on 12 December 2011

FADD expression as a prognosticator in early-stage glottic squamous cell carcinoma of the larynx treated primarily with radiotherapy

scientific article published on 28 December 2011

FADD expression is associated with regional and distant metastasis in squamous cell carcinoma of the head and neck

scientific article

FGFR Family Members Protein Expression as Prognostic Markers in Oral Cavity and Oropharyngeal Squamous Cell Carcinoma

scientific article published on 09 June 2016

Feasibility of patient specific quality assurance for proton therapy based on independent dose calculation and predicted outcomes

scientific article published on 21 June 2020

Feedback preferences of patients, professionals and health insurers in integrated head and neck cancer care.

scientific article published on 15 June 2017

Five year outcomes of hypofractionated simultaneous integrated boost irradiation in breast conserving therapy; patterns of recurrence

scientific article

Follow-up strategies in head and neck cancer other than upper aerodigestive tract squamous cell carcinoma.

scientific article published on 26 October 2012

Functional Swallowing Units (FSUs) as organs-at-risk for radiotherapy. PART 1: Physiology and anatomy

scientific article published on 09 November 2018

Functional Swallowing Units (FSUs) as organs-at-risk for radiotherapy. PART 2: Advanced delineation guidelines for FSUs

scientific article published on 11 December 2018

Gemcitabine-radiotherapy in patients with locally advanced pancreatic cancer.

scientific article

Geometric Image Biomarker Changes of the Parotid Gland Are Associated With Late Xerostomia

scientific article published on 12 August 2017

Grading system and management guidelines for dermatitis induced by head and neck radiotherapy plus cetuximab: clinical validation required ⬇️

scientific article published on August 29, 2011

Grading-system-dependent volume effects for late radiation-induced rectal toxicity after curative radiotherapy for prostate cancer

scientific article published on 10 October 2007

Has the degree of contrast enhancement with MR imaging in laryngeal carcinoma added value to anatomic parameters regarding prediction of response to radiation therapy?

scientific article

Head and neck intensity modulated radiation therapy leads to an increase of opportunistic oral pathogens

scientific article published on 27 May 2016

Head and neck squamous cell carcinomas do not express EGFRvIII.

scientific article

Head and neck tumor hypoxia imaging by 18F-fluoroazomycin-arabinoside (18F-FAZA)-PET: a review.

scientific article published on January 2014

Health status and voice outcome after treatment for T1a glottic carcinoma.

scientific article

Health-related quality of life and late morbidity in concurrent chemoradiation and radiotherapy alone in patients with locally advanced cervical carcinoma

scientific article

Health-related quality of life in patients surviving non-small cell lung cancer.

scientific article published in October 2010

High and low LET radiation differentially induce normal tissue damage signals.

scientific article published on 13 January 2012

High pATM is Associated With Poor Local Control in Supraglottic Cancer Treated With Radiotherapy

scientific article published on 10 April 2020

High prevalence of cachexia in newly diagnosed head and neck cancer patients: An exploratory study

scientific article

High rate of severe radiation dermatitis during radiation therapy with concurrent cetuximab in head and neck cancer: results of a survey in EORTC institutes

scientific article published on 30 October 2008

Higher laryngeal preservation rate after CO2 laser surgery compared with radiotherapy in T1a glottic laryngeal carcinoma

scientific article

Hypopharyngeal carcinoma after radiation for tuberculosis: radiation-induced carcinoma

scientific article published on 24 July 2010

Hypoxia imaging using Positron Emission Tomography in non-small cell lung cancer: implications for radiotherapy

scientific article published on 04 May 2012

Immediate postoperative radiotherapy in residual nonfunctioning pituitary adenoma: beneficial effect on local control without additional negative impact on pituitary function and life expectancy

scientific article published on 29 December 2006

Impact of late treatment-related toxicity on quality of life among patients with head and neck cancer treated with radiotherapy

scientific article

Impact of primary local treatment on the development of distant metastases or death through locoregional recurrence in young breast cancer patients

scientific article published on 03 August 2013

Impact of primary tumor volume on local control after definitive radiotherapy for head and neck cancer

scientific article published on 17 December 2013

Impact of radiation-induced xerostomia on quality of life after primary radiotherapy among patients with head and neck cancer

scientific article published on 8 June 2007

Impact of sarcopenia on survival and late toxicity in head and neck cancer patients treated with radiotherapy

scientific article published on 03 April 2020

Impact of statistical learning methods on the predictive power of multivariate normal tissue complication probability models

scientific article published on 13 January 2012

Improved detection of recurrent laryngeal tumor after radiotherapy using (18)FDG-PET as initial method

scientific article published on 7 March 2008

Improving automatic delineation for head and neck organs at risk by Deep Learning Contouring

scientific article published on 22 October 2019

Improving the prediction of overall survival for head and neck cancer patients using image biomarkers in combination with clinical parameters.

scientific article published on 29 July 2017

In Response to: Study to determine adequate margins in radiotherapy planning for esophageal carcinoma by detailing patterns of recurrence after definitive chemoradiotherapy

scientific article published in December 2009

In reply to Gemici

scientific article published on 26 September 2014

In vitro biological response of cancer and normal tissue cells to proton irradiation not affected by an added magnetic field

scientific article published on 11 May 2019

Incidence, causative mechanisms, and anatomic localization of stroke in pituitary adenoma patients treated with postoperative radiation therapy versus surgery alone.

scientific article published in September 2013

Indications for radiotherapy after neck dissection

scientific article

Individual patient information to select patients for different radiation techniques

scientific article published on 10 May 2016

Intensity-modulated radiotherapy reduces radiation-induced morbidity and improves health-related quality of life: results of a nonrandomized prospective study using a standardized follow-up program

scientific article

International Guideline on Dose Prioritization and Acceptance Criteria in Radiation Therapy Planning for Nasopharyngeal Carcinoma

scientific article published on 02 July 2019

International guideline for the delineation of the clinical target volumes (CTV) for nasopharyngeal carcinoma.

scientific article published on 15 November 2017

Investigation of inter-fraction target motion variations in the context of pencil beam scanned proton therapy in non-small cell lung cancer patients

scientific article published on 23 June 2020

Ipsilateral irradiation for oral and oropharyngeal carcinoma treated with primary surgery and postoperative radiotherapy

scientific article published on 25 February 2010

Is cardiac toxicity a relevant issue in the radiation treatment of esophageal cancer?

scientific article published on 30 December 2014

Is the chest radiograph a reliable tool in the assessment of tumor response after radiotherapy in nonsmall cell lung carcinoma? ⬇️

scientific article published on July 15, 1998

Is the coronary artery calcium score associated with acute coronary events in breast cancer patients treated with radiotherapy?

scientific article published on 28 October 2017

Key challenges in normal tissue complication probability model development and validation: towards a comprehensive strategy

scientific article published on 23 April 2020

Lack of DNA Damage Response at Low Radiation Doses in Adult Stem Cells Contributes to Organ Dysfunction

scientific article published on 22 August 2018

Laryngeal preservation with induction chemotherapy for hypopharyngeal squamous cell carcinoma: 10-year results of EORTC trial 24891

scientific article

Limited Impact of Setup and Range Uncertainties, Breathing Motion, and Interplay Effects in Robustly Optimized Intensity Modulated Proton Therapy for Stage III Non-small Cell Lung Cancer.

scientific article published on 29 June 2016

Limited benefit of inversely optimised intensity modulation in breast conserving radiotherapy with simultaneously integrated boost

scientific article published on 18 February 2010

Lobectomy or Sublobectomy for Small Non-Small-Cell Lung Cancer: The Question Remains

scientific article published on 28 November 2016

Local control in sinonasal malignant melanoma: Comparing conventional to hypofractionated radiotherapy

scientific article published on 16 October 2017

Log file-based dose reconstruction and accumulation for 4D adaptive pencil beam scanned proton therapy in a clinical treatment planning system: Implementation and proof-of-concept

scientific article published on 04 February 2019

Long-term Outcome of Surgery or Stereotactic Radiotherapy for Lung Oligometastases

scientific article published on 30 May 2017

Long-term efficacy of voice therapy in patients with voice problems after treatment of early glottic cancer.

scientific article published on 12 August 2011

Low levels of circulating invariant natural killer T cells predict poor clinical outcome in patients with head and neck squamous cell carcinoma

scientific article published on 01 March 2007

Lung irradiation induces pulmonary vascular remodelling resembling pulmonary arterial hypertension

scientific article published on 26 December 2011

Lymph node metastasis in nasal vestibule cancer: a review

scientific article published on 09 December 2010

Management of salivary gland tumors ⬇️

scientific article published on September 1, 2012

Massive haemoptysis after radiotherapy in inoperable non-small cell lung carcinoma: is endobronchial brachytherapy really a risk factor?

scientific article published on 01 November 1998

Metastatic Squamous Cell Carcinoma to the Cervical Lymph Nodes From an Unknown Primary Cancer: Management in the HPV Era

scientific article published on 10 November 2020

Minimising contralateral breast dose in post-mastectomy intensity-modulated radiotherapy by incorporating conformal electron irradiation

scientific article published on 18 January 2010

More than 10% weight loss in head and neck cancer patients during radiotherapy is independently associated with deterioration in quality of life

scientific article published in January 2013

Mouth opening in patients irradiated for head and neck cancer: a prospective repeated measures study

scientific article

Multicenter validation of recursive partitioning analysis classification for patients with squamous cell head and neck carcinoma treated with surgery and postoperative radiotherapy

scientific article published on May 2007

Multicriteria optimization enables less experienced planners to efficiently produce high quality treatment plans in head and neck cancer radiotherapy

scientific article

Multimodal guided self-help exercise program to prevent speech, swallowing, and shoulder problems among head and neck cancer patients: a feasibility study

scientific article published on 06 March 2014

Multivariable normal tissue complication probability model-based treatment plan optimization for grade 2-4 dysphagia and tube feeding dependence in head and neck radiotherapy

scientific article published on 07 September 2016

Multivariate modeling of complications with data driven variable selection: guarding against overfitting and effects of data set size.

scientific article

NTCP models for patient-rated xerostomia and sticky saliva after treatment with intensity modulated radiotherapy for head and neck cancer: the role of dosimetric and clinical factors

scientific article published on 18 April 2012

Normal tissue complication probability (NTCP) models for late rectal bleeding, stool frequency and fecal incontinence after radiotherapy in prostate cancer patients

scientific article published on 3 May 2016

Objective Acoustic-Phonetic Speech Analysis in Patients Treated for Oral or Oropharyngeal Cancer

scientific article published on 01 July 2009

Oesophageal tumour progression between the diagnostic ¹⁸F-FDG-PET and the ¹⁸F-FDG-PET for radiotherapy treatment planning

scientific article published on 27 November 2012

Optimizing Radiotherapy in HPV-Associated Oropharyngeal Cancer Patients

scientific article

Optimizing dose prescription in stereotactic body radiotherapy for lung tumours using Monte Carlo dose calculation

scientific article published on 18 December 2009

Optimum dose range for the amelioration of long term radiation-induced hyposalivation using prophylactic pilocarpine treatment.

scientific article published on 19 November 2007

Options for salvage after failed initial treatment of anterior vocal commissure squamous carcinoma

scientific article

Organ sparing potential and inter-fraction robustness of adaptive intensity modulated proton therapy for lung cancer

scientific article published on 26 September 2019

Outcome impact and cost-effectiveness of quality assurance for radiotherapy planned for the EORTC 22071-24071 prospective study for head and neck cancer

scientific article published on 23 May 2014

Overexpression of intrinsic hypoxia markers HIF1alpha and CA-IX predict for local recurrence in stage T1-T2 glottic laryngeal carcinoma treated with radiotherapy.

scientific article published in September 2008

PET Imaging with S-[(11)C]Methyl-L-Cysteine and L-[Methyl-(11)C]Methionine in Rat Models of Glioma, Glioma Radiotherapy, and Neuroinflammation.

scientific article published on 30 October 2017

PET imaging of tumor hypoxia using 18F-fluoroazomycin arabinoside in stage III-IV non-small cell lung cancer patients.

scientific article

PTEN Is Associated With Worse Local Control in Early Stage Supraglottic Laryngeal Cancer Treated With Radiotherapy

scientific article published on 12 June 2019

Parameters Associated With Mandibular Osteoradionecrosis

scientific article published on 22 January 2018

Parotid gland fat related Magnetic Resonance image biomarkers improve prediction of late radiation-induced xerostomia

scientific article published on 26 June 2018

Particle therapy in Europe

scientific article published on 29 March 2020

Patient position verification with oblique radiation beams

scientific article published on 15 February 2007

Patients with advanced periodontal disease before intensity-modulated radiation therapy are prone to develop bone healing problems: a 2-year prospective follow-up study

scientific article

Patterns of long-term swallowing dysfunction after definitive radiotherapy or chemoradiation

scientific article published on 25 August 2015

Peripheral blood IFN-gamma-secreting Valpha24+Vbeta11+ NKT cell numbers are decreased in cancer patients independent of tumor type or tumor load

scientific article published on 01 August 2005

Permanent unilateral hearing loss after radiotherapy for parotid gland tumors

scientific article published in October 2006

Phosphorylated FADD is not prognostic for local control in T1-T2 supraglottic laryngeal carcinoma treated with radiotherapy

scientific article published on 17 March 2017

Physiological interaction of heart and lung in thoracic irradiation

scientific article published on 11 September 2012

Platform for automatic patient quality assurance via Monte Carlo simulations in proton therapy

scientific article published on 20 January 2020

Poor sleep quality among newly diagnosed head and neck cancer patients: prevalence and associated factors

scientific article published on 22 June 2020

Positive surgical margins in neck dissection specimens in patients with head and neck squamous cell carcinoma and the effect of radiotherapy

scientific article published on September 2000

Post-therapeutic surveillance strategies in head and neck squamous cell carcinoma

scientific article published on 13 September 2012

Postoperative elective nodal irradiation for squamous cell carcinoma of the head and neck: outcome and prognostic factors for regional recurrence

scientific article published on 01 March 2011

Postoperative radiotherapy in squamous cell carcinoma of the oral cavity: the importance of the overall treatment time

scientific article published on 01 November 2003

Postoperative strategies after primary surgery for squamous cell carcinoma of the head and neck.

scientific article published on 18 April 2010

Potential benefits of scanned intensity-modulated proton therapy versus advanced photon therapy with regard to sparing of the salivary glands in oropharyngeal cancer

scientific article published on 21 August 2010

Practical robustness evaluation in radiotherapy - A photon and proton-proof alternative to PTV-based plan evaluation

scientific article published on 03 September 2019

Practice recommendations for risk-adapted head and neck cancer radiotherapy during the COVID-19 pandemic: an ASTRO-ESTRO consensus statement

scientific article published on 14 April 2020

Pre-treatment radiomic features predict individual lymph node failure for head and neck cancer patients

scientific article published on 27 February 2020

Predictive modelling for swallowing dysfunction after primary (chemo)radiation: results of a prospective observational study.

scientific article

Predictors for trismus in patients receiving radiotherapy

scientific article published on 14 September 2016

Pretreatment quality of life of inoperable non-small cell lung cancer patients referred for primary radiotherapy

scientific article published in January 2000

Prevalence and clinical and psychological correlates of high fear of cancer recurrence in patients newly diagnosed with head and neck cancer

scientific article published on 07 June 2019

Prevalence and prediction of trismus in patients with head and neck cancer: A cross-sectional study

scientific article published on 18 December 2018

Prevalence of swallowing and speech problems in daily life after chemoradiation for head and neck cancer based on cut-off scores of the patient-reported outcome measures SWAL-QOL and SHI.

scientific article published on 14 June 2015

Primary treatment of the anterior vocal commissure squamous carcinoma

scientific article published on 15 August 2006

Prognostic factors for locoregional recurrences in colon cancer

scientific article published on 05 January 2012

Prognostic factors for tube feeding dependence after curative (chemo-) radiation in head and neck cancer: A systematic review of literature

scientific article published on 21 September 2017

Prognostic factors in adult soft tissue sarcomas of the head and neck: a single-centre experience

scientific article

Prognostic significance of HIF-1a, CA-IX, and OPN in T1-T2 laryngeal carcinoma treated with radiotherapy.

scientific article published in September 2013

Prophylactic exercises among head and neck cancer patients during and after swallowing sparing intensity modulated radiation: adherence and exercise performance levels of a 12-week guided home-based program

scientific article

Proposal for a rational classification of neck dissections

article

Prospective data registration and clinical trials for particle therapy in Europe

scientific article published on 07 July 2018

Prospective evaluation of health-related quality of life in long-term oral and oropharyngeal cancer survivors and the perceived need for supportive care

scientific article published on 11 January 2013

Prospective evaluation of voice outcome during the first two years in male patients treated by radiotherapy or laser surgery for T1a glottic carcinoma

scientific article

Prospective study on quality of life before and after radical radiotherapy in non-small-cell lung cancer.

scientific article

Protection of salivary function by concomitant pilocarpine during radiotherapy: a double-blind, randomized, placebo-controlled study

scientific article published on 14 September 2007

Protons in head-and-neck cancer: bridging the gap of evidence.

scientific article

Pulmonary Function Changes After Radiotherapy for Lung or Esophageal Cancer: A Systematic Review Focusing on Dose-Volume Parameters

scientific article published on 26 May 2017

Pulmonary oligometastases: metastasectomy or stereotactic ablative radiotherapy?

scientific article published on 14 June 2013

Quality assurance for the EORTC 22071-26071 study: dummy run prospective analysis.

scientific article

Quality assurance in head and neck surgical oncology: EORTC 24954 trial on larynx preservation

scientific article published on 28 June 2013

Quality of life after curative radiotherapy in Stage I non-small-cell lung cancer

scientific article published on 01 July 2002

Quality of life after palliative radiotherapy in non-small cell lung cancer: a prospective study

scientific article

Quality of life after surgical treatment for oral and oropharyngeal cancer: a prospective longitudinal assessment of patients reconstructed by a microvascular flap

scientific article published on 16 February 2007

Quality of life among prostate cancer patients: a prospective longitudinal population-based study

scientific article

Quality of life as predictor of survival: a prospective study on patients treated with combined surgery and radiotherapy for advanced oral and oropharyngeal cancer

scientific article

Quality of life in patients with head and neck cancer receiving targeted or multimodal therapy--update of the EORTC QLQ-H&N35, Phase I.

scientific article published on 21 August 2012

Quality-of-life after radiotherapy for advanced laryngeal cancer: Results of a phase III trial of the Dutch Head and Neck Society.

scientific article

Quantifying local radiation-induced lung damage from computed tomography

scientific article published on 01 February 2010

Radiation dose associated with local control in advanced anal cancer: retrospective analysis of 129 patients

scientific article published on 22 May 2008

Radiation dose constraints for organs at risk in neuro-oncology; the European Particle Therapy Network consensus

scientific article published on 17 May 2018

Radiation-Induced Sarcomas of the Head and Neck: A Systematic Review

scientific article published on 13 November 2020

Radiation-induced carotid artery lesions

scientific article published on 20 April 2018

Radiation-induced fibrosis in the boost area after three-dimensional conformal radiotherapy with a simultaneous integrated boost technique for early-stage breast cancer: A multivariable prediction model

scientific article published on 25 October 2016

Radiation-induced hypothyroidism in head and neck cancer patients: a systematic review

scientific article

Radiotherapy alone, versus radiotherapy with amifostine 3 times weekly, versus radiotherapy with amifostine 5 times weekly: A prospective randomized study in squamous cell head and neck cancer

scientific article published on 01 August 2006

Radiotherapy for parapharyngeal space tumors

scientific article published on 21 December 2018

Radiotherapy is not associated with reduced quality of life and cognitive function in patients treated for nonfunctioning pituitary adenoma

scientific article published on 26 March 2007

Radiotherapy of squamous cell carcinoma of the nasal vestibule

scientific article published on 01 August 2004

Radiotherapy on the neck nodes predicts severe weight loss in patients with early stage laryngeal cancer

scientific article published on 10 March 2010

Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma

scientific article published in July 2002

Randomized controlled trial to identify the optimal radiotherapy scheme for palliative treatment of incurable head and neck squamous cell carcinoma

scientific article published on 14 May 2020

Re-irradiation of a second localization of idiopathic midline destructive disease in the head and neck area.

scientific article

Recent changes in the treatment of patients with advanced laryngeal cancer

scientific article published on January 2008

Reconstruction of high resolution MLC leaf positions using a low resolution detector for accurate 3D dose reconstruction in IMRT.

scientific article published on 7 November 2016

Reply letter to "Texture analysis of parotid gland as a predictive factor of radiation induced xerostomia: A subset analysis".

scientific article

Reply to Laprie A. et al

scientific article published on 13 November 2018

Reproducibility of the lung anatomy under active breathing coordinator control: Dosimetric consequences for scanned proton treatments

scientific article published on 19 October 2018

Residual ¹⁸F-FDG-PET uptake 12 weeks after stereotactic ablative radiotherapy for stage I non-small-cell lung cancer predicts local control

scientific article published on 13 March 2012

Resting energy expenditure in head and neck cancer patients before and during radiotherapy

scientific article

Results of postoperative reirradiation for recurrent or second primary head and neck carcinoma

scientific article published in April 2006

Risk-group definition by recursive partitioning analysis of patients with squamous cell head and neck carcinoma treated with surgery and postoperative radiotherapy

scientific article published in October 2005

Robust Intensity Modulated Proton Therapy (IMPT) Increases Estimated Clinical Benefit in Head and Neck Cancer Patients

scientific article

Role of minor salivary glands in developing patient-rated xerostomia and sticky saliva during day and night

scientific article published on 15 August 2013

Role of radiotherapy fractionation in head and neck cancers (MARCH): an updated meta-analysis

scientific article published on 27 July 2017

Screening for distant metastases in patients with head and neck cancer: is chest computed tomography sufficient?

scientific article published in October 2005

Screening for distant metastases in patients with head and neck cancer: what is the current clinical practice?

scientific article published on 01 October 2005

Scrotal irradiation in primary testicular lymphoma: review of the literature and in silico planning comparative study

scientific article published on 24 July 2012

Selection of head and neck cancer patients for adaptive radiotherapy to decrease xerostomia

scientific article published on 23 June 2016

Selection of lymph node target volumes for definitive head and neck radiation therapy: a 2019 Update

scientific article published on 30 January 2019

Selection of patients for radiotherapy with protons aiming at reduction of side effects: the model-based approach

scientific article published on 05 June 2013

Severe comorbidity negatively influences prognosis in patients with oral and oropharyngeal cancer after surgical treatment with microvascular reconstruction

scientific article published on 01 April 2005

Simultaneous integrated boost irradiation after breast-conserving surgery: physician-rated toxicity and cosmetic outcome at 30 months' follow-up.

scientific article published on 10 April 2012

Sparing the region of the salivary gland containing stem cells preserves saliva production after radiotherapy for head and neck cancer.

scientific article published on September 2015

Speech outcome after surgical treatment for oral and oropharyngeal cancer: a longitudinal assessment of patients reconstructed by a microvascular flap

scientific article published in September 2005

Standardised Ki-67 proliferation index assessment in early-stage laryngeal squamous cell carcinoma in relation to local control and survival after primary radiotherapy

scientific article published on 05 November 2019

Statistical validation of normal tissue complication probability models.

scientific article published on 27 April 2012

Strategies to promote translational research within the European Organisation for Research and Treatment of Cancer (EORTC) Head and Neck Cancer Group: a report from the Translational Research Subcommittee

scientific article

Supraglottic carcinoma treated with curative radiation therapy: identification of prognostic groups with MR imaging

scientific article published on 01 August 2004

Survival Patterns in Elderly Head and Neck Squamous Cell Carcinoma Patients Treated With Definitive Radiation Therapy

scientific article published on 6 March 2017

Survival after definitive (chemo)radiotherapy in esophageal cancer patients: a population-based study in the north-East Netherlands

scientific article published on 29 December 2012

Survival and quality of life after stereotactic or 3D-conformal radiotherapy for inoperable early-stage lung cancer

scientific article published on 2 June 2011

Swallowing after major surgery of the oral cavity or oropharynx: A prospective and longitudinal assessment of patients treated by microvascular soft tissue reconstruction

scientific article published on 01 July 2007

Swallowing sparing intensity modulated radiotherapy (SW-IMRT) in head and neck cancer: Clinical validation according to the model-based approach

scientific article published on 14 December 2015

Swallowing-sparing intensity-modulated radiotherapy for head and neck cancer patients: treatment planning optimization and clinical introduction

scientific article published on 03 June 2013

Synergistic induction of profibrotic PAI-1 by TGF-β and radiation depends on p53.

scientific article

Systematic review and meta-analysis of radiotherapy in various head and neck cancers: comparing photons, carbon-ions and protons.

scientific article published on May 2011

The Acute and Early Effects of Whole-Brain Irradiation on Glial Activation, Brain Metabolism, and Behavior: a Positron Emission Tomography Study

scientific article published on 12 February 2020

The Groningen Radiotherapy-Induced Xerostomia questionnaire: development and validation of a new questionnaire

scientific article published on 10 June 2010

The In Vitro Response of Tissue Stem Cells to Irradiation With Different Linear Energy Transfers.

scientific article published on 12 February 2016

The QUANTEC criteria for parotid gland dose and their efficacy to prevent moderate to severe patient-rated xerostomia.

scientific article published on 2 September 2013

The Quest for Evidence for Proton Therapy: Model-Based Approach and Precision Medicine.

scientific article published on 9 October 2015

The additional value of chemotherapy to radiotherapy in locally advanced nasopharyngeal carcinoma: a meta-analysis of the published literature

scientific article published on 01 November 2004

The cost of setting up and operating a hadron facility. In regard to Vanderstraeten et al

scientific article published on 01 September 2014

The course of health-related quality of life in head and neck cancer patients treated with chemoradiation: a prospective cohort study

scientific article published on 25 February 2014

The effect of induction chemotherapy on tumor volume and organ-at-risk doses in patients with locally advanced oropharyngeal cancer.

scientific article published on 16 November 2013

The efficacy of voice therapy in patients after treatment for early glottic carcinoma.

scientific article published in January 2006

The impact of age on changes in quality of life among breast cancer survivors treated with breast-conserving surgery and radiotherapy

scientific article

The impact of comorbidity on treatment-related side effects in older patients with laryngeal cancer

scientific article published on 15 December 2010

The impact of gastrointestinal and genitourinary toxicity on health related quality of life among irradiated prostate cancer patients

scientific article

The impact of heart irradiation on dose-volume effects in the rat lung

scientific article published on 01 October 2007

The impact of late treatment-toxicity on generic health-related quality of life in head and neck cancer patients after radiotherapy

scientific article published on 17 June 2011

The importance of immunohistochemical expression of EGFr in squamous cell carcinoma of the oral cavity treated with surgery and postoperative radiotherapy

scientific article published on 05 June 2006

The incidence of second tumours and mortality in pituitary adenoma patients treated with postoperative radiotherapy versus surgery alone.

scientific article published on 8 June 2012

The phosphatase and tensin homologue deleted on chromosome 10 mediates radiosensitivity in head and neck cancer.

scientific article

The potential benefit of radiotherapy with protons in head and neck cancer with respect to normal tissue sparing: a systematic review of literature

scientific article published on 24 February 2011

The potential benefit of swallowing sparing intensity modulated radiotherapy to reduce swallowing dysfunction: an in silico planning comparative study

scientific article published on 21 November 2011

The potential of intensity-modulated proton radiotherapy to reduce swallowing dysfunction in the treatment of head and neck cancer: A planning comparative study

scientific article published on 19 June 2012

The prevalence of hypothyroidism after treatment for laryngeal and hypopharyngeal carcinomas: are autoantibodies of influence?

scientific article published on 01 March 2007

The prognostic significance of accumulation of p53 protein in stage III non-small cell lung cancer treated by radiotherapy

scientific article published on 01 September 1995

The prognostic significance of p16 overexpression in oropharyngeal squamous cell carcinoma: implications for treatment strategies and future clinical studies

scientific article published on 17 August 2010

The prognostic value of CT-based image-biomarkers for head and neck cancer patients treated with definitive (chemo-)radiation

scientific article published on 26 June 2019

The psychometric and clinical validity of the SWAL-QOL questionnaire in evaluating swallowing problems experienced by patients with oral and oropharyngeal cancer.

scientific article

The significance of anemia in squamous cell head and neck cancer treated with surgery and postoperative radiotherapy

scientific article published on 16 September 2005

Three-dimensional conformal hypofractionated simultaneous integrated boost in breast conserving therapy: results on local control and survival

scientific article published on 2 June 2011

Three-dimensional conformal simultaneously integrated boost technique for breast-conserving radiotherapy

scientific article published on 26 March 2007

Treatment of late sequelae after radiotherapy for head and neck cancer

scientific article published on 18 July 2017

Tyrosine positron emission tomography and protein synthesis rate in pituitary adenoma: different effects of surgery and radiation therapy

scientific article published on 4 February 2011

Unilateral versus bilateral irradiation in squamous cell head and neck cancer in relation to patient-rated xerostomia and sticky saliva

scientific article published on 27 March 2007

Updating Photon-based Normal Tissue Complication Probability Models for Pneumonitis in Lung Cancer Patients Treated with Proton Beam Therapy

scientific article published on 13 May 2020

Using a reduced spot size for intensity-modulated proton therapy potentially improves salivary gland-sparing in oropharyngeal cancer.

scientific article published on 25 June 2011

Validation and Modification of a Prediction Model for Acute Cardiac Events in Patients With Breast Cancer Treated With Radiotherapy Based on Three-Dimensional Dose Distributions to Cardiac Substructures

scientific article published on 17 January 2017

Validation of a gene expression signature for assessment of lymph node metastasis in oral squamous cell carcinoma.

scientific article

Validation of linear energy transfer computed in a Monte Carlo dose engine of a commercial treatment planning system

scientific article published on 17 January 2020

Validation of the proton range accuracy and optimization of CT calibration curves utilizing range probing

scientific article published on 04 February 2020

Validation of the total dysphagia risk score (TDRS) in head and neck cancer patients in a conventional and a partially accelerated radiotherapy scheme.

scientific article

Validity of bioelectrical impedance analysis to assess fat-free mass in patients with head and neck cancer: an exploratory study.

scientific article

Variation in lymph node evaluation in rectal cancer: a Dutch nationwide population-based study

scientific article published on 24 August 2010

Variation in treatment and outcome of patients with rectal cancer by region, hospital type and volume in the Netherlands.

scientific article

Viable tumor in salvage neck dissections in head and neck cancer: Relation with initial treatment, change of lymph node size and human papillomavirus

scientific article published on 08 January 2018

Visualization of small glottic laryngeal cancer using methyl-labeled 11C-methionine positron emission tomography.

scientific article published on 14 January 2009

Voice in early glottic cancer compared to benign voice pathology

scientific article published on 25 April 2007

Volume-dependent expression of in-field and out-of-field effects in the proton-irradiated rat lung

scientific article published on 24 May 2011

Whole breast proton irradiation for maximal reduction of heart dose in breast cancer patients

scientific article

ΔNp73 enhances promoter activity of TGF-β induced genes

scientific article

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