List of works - Natalia Fernández-Borges

A Quick Method to Evaluate the Effect of the Amino Acid Sequence in the Misfolding Proneness of the Prion Protein

scientific article published in January 2017

A Single Amino Acid Substitution, Found in Mammals with Low Susceptibility to Prion Diseases, Delays Propagation of Two Prion Strains in Highly Susceptible Transgenic Mouse Models

scientific article published on 07 March 2019

A molecular switch controls interspecies prion disease transmission in mice

scientific article

Altered Ca2+ homeostasis induces Calpain-Cathepsin axis activation in sporadic Creutzfeldt-Jakob disease

scientific article

An Amino Acid Substitution Found in Animals with Low Susceptibility to Prion Diseases Confers a Protective Dominant-Negative Effect in Prion-Infected Transgenic Mice

scientific article published on 20 December 2017

An assessment of the long-term persistence of prion infectivity in aquatic environments

scientific article published in September 2016

Animal models for prion-like diseases.

scientific article published on 20 April 2015

Animal models for testing anti-prion drugs.

scientific article

Behind the potential evolution towards prion resistant species.

scientific article published in February 2018

Bovine spongiform encephalopathy induces misfolding of alleged prion-resistant species cellular prion protein without altering its pathobiological features.

scientific article published in May 2013

Canine D-PrP polymorphic variant does not provide complete protection against prion infection in small ruminant PrP context

scientific article

Characterization of mesenchymal stem cells in sheep naturally infected with scrapie

scientific article published on 2 October 2015

Cofactors influence the biological properties of infectious recombinant prions.

scientific article published in November 2017

DNA immunization of pigs with foot-and-mouth disease virus minigenes: from partial protection to disease exacerbation

scientific article published on 17 February 2011

DNA vaccination can break immunological tolerance to PrP in wild-type mice and attenuates prion disease after intracerebral challenge

scientific article published on October 2006

DNA vaccines expressing B and T cell epitopes can protect mice from FMDV infection in the absence of specific humoral responses

article

Detection of PrPres in genetically susceptible fetuses from sheep with natural scrapie

scientific article

Development of a new largely scalable in vitro prion propagation method for the production of infectious recombinant prions for high resolution structural studies

scientific article published on 23 October 2019

Dogs are resistant to prion infection, due to the presence of aspartic or glutamic acid at position 163 of their prion protein

scientific article published on 15 January 2020

Exploring the risks of a putative transmission of BSE to new species

scientific article

Generation of a new infectious recombinant prion: a model to understand Gerstmann-Sträussler-Scheinker syndrome

scientific article

Human prion protein sequence elements impede cross-species chronic wasting disease transmission

scientific article published on 11 May 2015

Human prion protein sequence elements impede cross-species chronic wasting disease transmission. ⬇️

scientific article

In Vitro Approach To Identify Key Amino Acids in Low Susceptibility of Rabbit Prion Protein to Misfolding

scientific article published on 4 October 2017

In vitro studies of the transmission barrier.

scientific article published on 30 October 2009

Infectivity versus Seeding in Neurodegenerative Diseases Sharing a Prion-Like Mechanism

scientific article

Insights into the Bidirectional Properties of the Sheep-Deer Prion Transmission Barrier

scientific article published on 27 December 2018

Naturally prion resistant mammals: a utopia?

scientific article

PMCA. A Decade of In Vitro Prion Replication

article by Natalia Fernandez-Borges & Joaquin Castilla published 1 September 2010 in Current chemical biology

PrPC Governs Susceptibility to Prion Strains in Bank Vole, While Other Host Factors Modulate Strain Features.

scientific article

Prion Diseases in Animals and Zoonotic Potential

scientific article published on 07 December 2016

Prion replication without host adaptation during interspecies transmissions.

scientific article

Prion transmission prevented by modifying the β2-α2 loop structure of host PrPC

scientific article published on January 2014

Prion-Associated Neurodegeneration Causes Both Endoplasmic Reticulum Stress and Proteasome Impairment in a Murine Model of Spontaneous Disease ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2021

Prion-resistant or prion-susceptible species, this is the question.

scientific article published on 8 May 2013

Prionemia and leukocyte-platelet-associated infectivity in sheep transmissible spongiform encephalopathy models.

scientific article published on 7 December 2011

Protective Effect of Val129-PrP against Bovine Spongiform Encephalopathy but not Variant Creutzfeldt-Jakob Disease.

scientific article published on September 2017

Rabbits are not resistant to prion infection

scientific article published on 13 March 2012

Recent advances in the development of recombinant vaccines against classical swine fever virus: cellular responses also play a role in protection

scientific article published on 04 September 2007

Recombinant PrPSc shares structural features with brain-derived PrPSc: Insights from limited proteolysis.

scientific article published on 31 January 2018

Regional and subtype-dependent miRNA signatures in sporadic Creutzfeldt-Jakob disease are accompanied by alterations in miRNA silencing machinery and biogenesis.

scientific article published on 22 January 2018

Structure of the β2-α2 loop and interspecies prion transmission

scientific article

Susceptibility of European red deer (Cervus elaphus elaphus) to alimentary challenge with bovine spongiform encephalopathy

scientific article

Transgenic Mouse Bioassay: Evidence That Rabbits Are Susceptible to a Variety of Prion Isolates

scientific article

Transgenic fatal familial insomnia mice indicate prion infectivity-independent mechanisms of pathogenesis and phenotypic expression of disease

scientific article

Transmission and Replication of Prions.

scientific article published on 7 August 2017

Ultra-efficient PrP(Sc) amplification highlights potentialities and pitfalls of PMCA technology

scientific article

Unraveling the key to the resistance of canids to prion diseases

scientific article

YKL-40 in the brain and cerebrospinal fluid of neurodegenerative dementias.

scientific article published on 10 November 2017

iPS Cell Cultures from a Gerstmann-Sträussler-Scheinker Patient with the Y218N PRNP Mutation Recapitulate tau Pathology.

scientific article published on 2 May 2017

List of works by Natalia Fernández-Borges

A Quick Method to Evaluate the Effect of the Amino Acid Sequence in the Misfolding Proneness of the Prion Protein

A Single Amino Acid Substitution, Found in Mammals with Low Susceptibility to Prion Diseases, Delays Propagation of Two Prion Strains in Highly Susceptible Transgenic Mouse Models

A molecular switch controls interspecies prion disease transmission in mice

Altered Ca2+ homeostasis induces Calpain-Cathepsin axis activation in sporadic Creutzfeldt-Jakob disease

An Amino Acid Substitution Found in Animals with Low Susceptibility to Prion Diseases Confers a Protective Dominant-Negative Effect in Prion-Infected Transgenic Mice

An assessment of the long-term persistence of prion infectivity in aquatic environments

Animal models for prion-like diseases.

Animal models for testing anti-prion drugs.

Behind the potential evolution towards prion resistant species.

Bovine spongiform encephalopathy induces misfolding of alleged prion-resistant species cellular prion protein without altering its pathobiological features.

Canine D-PrP polymorphic variant does not provide complete protection against prion infection in small ruminant PrP context

Characterization of mesenchymal stem cells in sheep naturally infected with scrapie

Cofactors influence the biological properties of infectious recombinant prions.

DNA immunization of pigs with foot-and-mouth disease virus minigenes: from partial protection to disease exacerbation

DNA vaccination can break immunological tolerance to PrP in wild-type mice and attenuates prion disease after intracerebral challenge

DNA vaccines expressing B and T cell epitopes can protect mice from FMDV infection in the absence of specific humoral responses

Detection of PrPres in genetically susceptible fetuses from sheep with natural scrapie

Development of a new largely scalable in vitro prion propagation method for the production of infectious recombinant prions for high resolution structural studies

Dogs are resistant to prion infection, due to the presence of aspartic or glutamic acid at position 163 of their prion protein

Exploring the risks of a putative transmission of BSE to new species

Generation of a new infectious recombinant prion: a model to understand Gerstmann-Sträussler-Scheinker syndrome

Human prion protein sequence elements impede cross-species chronic wasting disease transmission

Human prion protein sequence elements impede cross-species chronic wasting disease transmission. ⬇️

In Vitro Approach To Identify Key Amino Acids in Low Susceptibility of Rabbit Prion Protein to Misfolding

In vitro studies of the transmission barrier.

Infectivity versus Seeding in Neurodegenerative Diseases Sharing a Prion-Like Mechanism

Insights into the Bidirectional Properties of the Sheep-Deer Prion Transmission Barrier

Naturally prion resistant mammals: a utopia?

PMCA. A Decade of In Vitro Prion Replication

PrPC Governs Susceptibility to Prion Strains in Bank Vole, While Other Host Factors Modulate Strain Features.

Prion Diseases in Animals and Zoonotic Potential

Prion replication without host adaptation during interspecies transmissions.

Prion transmission prevented by modifying the β2-α2 loop structure of host PrPC

Prion-Associated Neurodegeneration Causes Both Endoplasmic Reticulum Stress and Proteasome Impairment in a Murine Model of Spontaneous Disease ⬇️

Prion-resistant or prion-susceptible species, this is the question.

Prionemia and leukocyte-platelet-associated infectivity in sheep transmissible spongiform encephalopathy models.

Protective Effect of Val129-PrP against Bovine Spongiform Encephalopathy but not Variant Creutzfeldt-Jakob Disease.

Rabbits are not resistant to prion infection

Recent advances in the development of recombinant vaccines against classical swine fever virus: cellular responses also play a role in protection

Recombinant PrPSc shares structural features with brain-derived PrPSc: Insights from limited proteolysis.

Regional and subtype-dependent miRNA signatures in sporadic Creutzfeldt-Jakob disease are accompanied by alterations in miRNA silencing machinery and biogenesis.

Structure of the β2-α2 loop and interspecies prion transmission

Susceptibility of European red deer (Cervus elaphus elaphus) to alimentary challenge with bovine spongiform encephalopathy

Transgenic Mouse Bioassay: Evidence That Rabbits Are Susceptible to a Variety of Prion Isolates

Transgenic fatal familial insomnia mice indicate prion infectivity-independent mechanisms of pathogenesis and phenotypic expression of disease

Transmission and Replication of Prions.

Ultra-efficient PrP(Sc) amplification highlights potentialities and pitfalls of PMCA technology

Unraveling the key to the resistance of canids to prion diseases

YKL-40 in the brain and cerebrospinal fluid of neurodegenerative dementias.

iPS Cell Cultures from a Gerstmann-Sträussler-Scheinker Patient with the Y218N PRNP Mutation Recapitulate tau Pathology.