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List of works by Celia F. Brosnan

15-deoxy-Delta12,14-prostaglandin J2 inhibits IFN-inducible protein 10/CXC chemokine ligand 10 expression in human microglia: mechanisms and implications

scientific article

15-deoxy-delta (12,14)-PGJ2 inhibits astrocyte IL-1 signaling: inhibition of NF-kappaB and MAP kinase pathways and suppression of cytokine and chemokine expression

scientific article

A comparison of methods for RNA extraction from lymphocytes for RT-PCR ⬇️

scientific article published on 01 December 1994

A critical role for IL-4 in regulating disease severity in experimental allergic encephalomyelitis as demonstrated in IL-4-deficient C57BL/6 mice and BALB/c mice ⬇️

scientific article published on May 15, 1998

A pathogenic role for gamma delta T cells in relapsing-remitting experimental allergic encephalomyelitis in the SJL mouse

scientific article published on 01 July 1996

Abnormal tubulin aggregates induced by zinc sulfate in organotypic cultures of nerve tissue

scientific article published on 01 January 1978

Activation of C-C beta-chemokines in human peripheral blood gammadelta T cells by isopentenyl pyrophosphate and regulation by cytokines.

scientific article

Amelioration of proteolipid protein 139-151-induced encephalomyelitis in SJL mice by modified amino acid copolymers and their mechanisms

scholarly article

Analysis of humoral and cellular events and the role of lipid haptens during CNS demyelination

scientific article published on 01 January 1983

Antigen presenting capacity of brain microvasculature in altered peptide ligand modulation of experimental allergic encephalomyelitis

scientific article published on January 1999

Antigen-induced suppression of mitogen responses and resistance to experimental autoimmune encephalomyelitis

scientific article published in May 1983

Antigen-specific T cells can mediate demyelination in organotypic central nervous system cultures

scientific article published on 01 October 1986

Astrocyte Involvement in the Acquired Demyelinating Diseases

Astrocyte indoleamine 2,3-dioxygenase is induced by the TLR3 ligand poly(I:C): mechanism of induction and role in antiviral response

scientific article

Astrocytic reactivity and intermediate filament metabolism in experimental autoimmune encephalomyelitis: the effect of suppression with prazosin

scientific article published in November 1986

Axl-/- mice have delayed recovery and prolonged axonal damage following cuprizone toxicity

scientific journal article

Brain-derived heat shock protein 70-peptide complexes induce NK cell-dependent tolerance to experimental autoimmune encephalomyelitis.

scientific article published in February 2006

CD1b is expressed in multiple sclerosis lesions

scientific article published on 01 July 1996

CSF-1 expression is upregulated in astrocyte cultures by IL-1 and TNF and affects microglial proliferation and morphology in organotypic cultures

scientific article published in April 1993

Canonical transient receptor potential channel 4 (TRPC4) co-localizes with the scaffolding protein ZO-1 in human fetal astrocytes in culture

scientific article

Characterization of primary human fetal dissociated central nervous system cultures with an emphasis on microglia

scientific article published on October 1, 1992

Chronic inflammatory effects of interleukin-1 on the blood-retina barrier

scientific article published on 01 December 1992

Chronic-relapsing experimental autoimmune encephalomyelitis. Myelin basic protein induces suppression of blastogenesis during remissions but not during exacerbations

scientific article published on February 1985

Colocalization of lymphocytes bearing gamma delta T-cell receptor and heat shock protein hsp65+ oligodendrocytes in multiple sclerosis ⬇️

scientific article published on August 1, 1991

Complement potentiates the degradation of myelin proteins by plasmin: implications for a mechanism of inflammatory demyelination

scientific article published in January 1986

Copolymer I: effect on normal human lymphocytes

scientific article published on 01 January 1984

Copolymer effects on microglia and T cells in the central nervous system of humanized mice

scientific article published in December 2005

Curcumin inhibits activation of Vgamma9Vdelta2 T cells by phosphoantigens and induces apoptosis involving apoptosis-inducing factor and large scale DNA fragmentation

scientific article

Cutting edge: purinergic signaling regulates radical-mediated bacterial killing mechanisms in macrophages through a P2X7-independent mechanism

scientific journal article

Cytokine Regulation of iNOS Expression in Human Glial Cells

scientific article published on August 1996

Cytokine cytotoxicity against oligodendrocytes. Apoptosis induced by lymphotoxin

scientific article

Cytokine induction of MIP-1 alpha and MIP-1 beta in human fetal microglia ⬇️

scientific article published on February 1, 1998

Cytokine localization in multiple sclerosis lesions: correlation with adhesion molecule expression and reactive nitrogen species

scientific article published on June 1995

Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta.

scientific article published in April 1993

Cytokine regulation of gap junction connectivity: an open-and-shut case or changing partners at the Nexus?

scientific article published on May 2001

Cytokine, chemokine and chemokine receptor mRNA expression in different strains of normal mice: implications for establishment of a Th1/Th2 bias

scientific article published in December 1999

Cytokine-induced inflammation in the central nervous system revisited

scientific article published on March 1, 1998

Cytokines: powerful regulators of glial cell activation

scientific article

Cytoskeletal alterations in human fetal astrocytes induced by interleukin-1 beta.

scientific article published in November 1994

Degradation of the P0, P1, and Pr, Proteins in Peripheral Nervous System Myelin by Plasmin: Implications Regarding the Role of Macrophages in Demyelinating Diseases ⬇️

scientific article published on 01 April 1981

Delayed onset of experimental allergic neuritis in rats treated with reserpine

scientific article published on January 1984

Deletion of astrocyte connexins 43 and 30 leads to a dysmyelinating phenotype and hippocampal CA1 vacuolation.

scientific article published on June 2009

Delta 9-tetrahydrocannabinol: a novel treatment for experimental autoimmune encephalomyelitis

scientific article

Developmental plasticity of CNS microglia

scientific article

Differential chemokine induction by the mouse adenovirus type-1 in the central nervous system of susceptible and resistant strains of mice.

scientific article published on February 1999

Differential effects of transforming growth factor-beta 1 on interleukin-1-induced cellular inflammation and vascular permeability in the rabbit retina

scientific article published on 01 October 1996

Differential induction of chemokines in human microglia by type I and II interferons

scientific article published on 01 February 2000

EAE serum decreases CNPase activity in cultures of B104 cells

scientific article published in January 1988

EAE tolerance induction with Hsp70-peptide complexes depends on H60 and NKG2D activity

scientific article published on 01 October 2007

Effects of prazosin on the blood-brain barrier during experimental autoimmune encephalomyelitis

scientific article published on October 30, 1992

Effects of zinc on the cytoskeletal proteins in the central nervous system of the rat

scientific article published on 01 September 1981

Electrophysiological analysis of factors involved in the primary demyelinating diseases: the rabbit eye model system

scientific article

Evidence for gammadelta T cells with a restricted Vgamma6 junctional region in the normal mouse central nervous system

scientific article published on 01 December 1999

Evidence of persistent blood-brain barrier abnormalities in chronic-progressive multiple sclerosis

scientific article published on 01 January 1995

Exacerbation of experimental autoimmune encephalomyelitis in P2X7R-/- mice: evidence for loss of apoptotic activity in lymphocytes

scientific journal article

Experimental allergic encephalomyelitis. Characterization of serum factors causing demyelination and swelling of myelin

scientific article published on 01 April 1981

Experimental autoimmune encephalomyelitis disrupts endocannabinoid-mediated neuroprotection

scholarly article

Experimental autoimmune encephalomyelitis on the SJL mouse: effect of gamma delta T cell depletion on chemokine and chemokine receptor expression in the central nervous system

scientific article published on 01 February 2000

Experimental autoimmune encephalomyelitis. Qualitative and semiquantitative differences in heat shock protein 60 expression in the central nervous system

scientific article published on 01 April 1995

Expression of CSF-1, c-fms, and MCP-1 in the central nervous system of rats with experimental allergic encephalomyelitis

scientific article published on 01 March 1993

Expression of Glial Fibrillary Acidic Protein and Neurofilament mRNA in Gliosis Induced by Experimental Autoimmune Encephalomyelitis ⬇️

scientific article published on 01 April 1990

Expression of heat shock protein-65 by oligodendrocytes in vivo and in vitro: implications for multiple sclerosis

scientific article published on April 1, 1992

Expression of inducible nitric oxide synthase and nitrotyrosine in multiple sclerosis lesions

scientific article

Expression of monocyte/macrophage growth factors and receptors in the central nervous system

scientific article published on January 1993

Expression of type II nitric oxide synthase in primary human astrocytes and microglia: role of IL-1beta and IL-1 receptor antagonist

scientific article published on 01 October 1996

Extracellular nucleotides differentially regulate interleukin-1beta signaling in primary human astrocytes: implications for inflammatory gene expression.

scientific article published in June 2001

Fetal human cortical neurons grown in culture: morphological differentiation, biochemical correlates and development of electrical activity

scientific article

Further studies on the inflammatory response induced by zinc wire implants in the central nervous system of rats

scientific article published on 01 March 1982

GM-CSF promotes proliferation of human fetal and adult microglia in primary cultures

scientific article

Gamma delta T cell receptor analysis supports a role for HSP 70 selection of lymphocytes in multiple sclerosis lesions

scientific article

Gangliosides offer partial protection in experimental allergic neuritis

scientific article published in January 1990

Gas6/Axl signaling activates the phosphatidylinositol 3-kinase/Akt1 survival pathway to protect oligodendrocytes from tumor necrosis factor alpha-induced apoptosis

scientific article

Glial fibrillary acidic protein increases in the spinal cord of Lewis rats with acute experimental autoimmune encephalomyelitis

scientific article published in October 1988

Gliosis in the spinal cords of rats with experimental allergic encephalomyelitis: immunostaining of carbonic anhydrase and vimentin in reactive astrocytes

scientific article published in January 1989

Granulocyte-macrophage colony-stimulating factor induces an expression program in neonatal microglia that primes them for antigen presentation

scientific article published on 01 September 2002

Heat shock protein 70 associations with myelin basic protein and proteolipid protein in multiple sclerosis brains.

scientific article published in February 2003

Heat shock proteins and multiple sclerosis: a review.

scientific article published on April 1996

Heat-shock proteins and immunopathology. An overview

scientific article published on January 1, 1992

Homing to central nervous system vasculature by antigen-specific lymphocytes. I. Localization of 14C-labeled cells during acute, chronic, and relapsing experimental allergic encephalomyelitis

scientific article published on August 1, 1990

Human astrocytes inhibit Cryptococcus neoformans growth by a nitric oxide-mediated mechanism

scientific article

Humoral response to hsp 65 in multiple sclerosis and other neurologic conditions

scientific article published on 01 May 1994

Hypothesis: a role for tumor necrosis factor in immune-mediated demyelination and its relevance to multiple sclerosis

scientific article published on April 1988

Hypothesis: antigen-specific T cells prime central nervous system endothelium for recruitment of nonspecific inflammatory cells to effect autoimmune demyelination

scientific article published on September 1991

IFNs are critical regulators of IL-1 receptor antagonist and IL-1 expression in human microglia ⬇️

scientific article published on August 15, 1998

IL-1-regulated responses in astrocytes: relevance to injury and recovery

scientific article

IL-10 fails to abrogate experimental autoimmune encephalomyelitis

scientific article published on 01 September 1996

IL-12-mediated NKRP1A up-regulation and consequent enhancement of endothelial transmigration of V delta 2+ TCR gamma delta+ T lymphocytes from healthy donors and multiple sclerosis patients

scientific article published on 01 April 1999

IL-1beta differentially regulates calcium wave propagation between primary human fetal astrocytes via pathways involving P2 receptors and gap junction channels.

scientific article published on September 1999

IL-1beta regulates blood-brain barrier permeability via reactivation of the hypoxia-angiogenesis program

scientific article published in October 2006

Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions

scientific article published in March 1991

Immunogenic potentials of copolymer I in normal human lymphocytes

scientific article published in December 1985

Immunopathology of allergic encephalomyelitis

scientific article published on 01 January 1980

In human fetal astrocytes exposure to interleukin-1 beta stimulates acquisition of the GD3+ phenotype and inhibits cell division

scientific article published on 01 April 1995

Increased vesicular transport and decreased mitochondrial content in blood-brain barrier endothelial cells during experimental autoimmune encephalomyelitis

scientific article

Inducible heat shock protein 70 promotes myelin autoantigen presentation by the HLA class II.

scientific article published on January 2004

Induction and suppression of an autoimmune disease by oligomerized T cell epitopes: enhanced in vivo potency of encephalitogenic peptides

scientific article

Induction of nitric oxide synthase activity in human astrocytes by interleukin-1 beta and interferon-gamma

scientific article published on 01 July 1993

Insulin-like growth factor-I prevents development of a vincristine neuropathy in mice ⬇️

scientific article published on November 7, 1997

Interferon-beta activates multiple signaling cascades in primary human microglia

scientific article

Interleukin-1, nitric oxide and reactive astrocytes

scientific article published on December 1995

Interleukin-11 potentiates oligodendrocyte survival and maturation, and myelin formation.

scientific article

Interleukin-1beta induces a reactive astroglial phenotype via deactivation of the Rho GTPase-Rock axis.

scientific article published in March 2004

Interleukin-1beta-induced expression of monocyte chemotactic protein-1 in the rabbit retina: an in situ and immunohistochemical study

scientific article published on 01 May 2000

Involvement of classical and novel protein kinase C isoforms in the response of human V gamma 9V delta 2 T cells to phosphate antigens.

scientific article published in November 2002

Localization of monocyte chemoattractant peptide-1 expression in the central nervous system in experimental autoimmune encephalomyelitis and trauma in the rat.

scientific article

Loss of Allograft Inflammatory Factor-1 Ameliorates Experimental Autoimmune Encephalomyelitis by Limiting Encephalitogenic CD4 T-Cell Expansion

scientific article published on 6 January 2015

Loss of astrocyte connexins 43 and 30 does not significantly alter susceptibility or severity of acute experimental autoimmune encephalomyelitis in mice

scientific article

Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during experimental autoimmune encephalomyelitis

scientific article

MCP-1, MCP-2 and MCP-3 expression in multiple sclerosis lesions: an immunohistochemical and in situ hybridization study ⬇️

scientific article published on June 1, 1998

MR microscopy of transgenic mice that spontaneously acquire experimental allergic encephalomyelitis.

scientific article published in July 1998

Macrophage Oxidative Metabolism: A Defense Mechanism Against Virus Infection? ⬇️

scientific article published on January 1, 1983

Macrophage colony-stimulating factor in human fetal astrocytes and microglia. Differential regulation by cytokines and lipopolysaccharide, and modulation of class II MHC on microglia

scientific article published in January 1993

Macrophage colony-stimulating factor mediates astrocyte-induced microglial ramification in human fetal central nervous system culture.

scientific article published in July 1994

Macrophages and microglia in HIV-related CNS neuropathology

scientific article published on January 1994

Mechanisms and suppression of inflammatory demyelination

scientific article published on January 1990

Mechanisms of autoimmune neuropathies

scientific article published on January 1990

Mechanisms of edema formation in experimental autoimmune encephalomyelitis. The contribution of inflammatory cells

scientific article published on November 1990

Mechanisms of immune injury in multiple sclerosis

scientific article published on July 1996

Mice Devoid of Tau Have Increased Susceptibility to Neuronal Damage in Myelin Oligodendrocyte Glycoprotein-Induced Experimental Autoimmune Encephalomyelitis ⬇️

scientific article published on May 1, 2012

Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease

scientific article published on January 1993

Microglia in human disease, with an emphasis on acquired immune deficiency syndrome.

scientific article published on February 1991

Microglial involvement in the acquired immunodeficiency syndrome (AIDS)

scientific article published on 01 April 1994

Modified amino acid copolymers suppress myelin basic protein 85-99-induced encephalomyelitis in humanized mice through different effects on T cells

scholarly article

Modulation of astrocyte inducible nitric oxide synthase and cytokine expression by interferon beta is associated with induction and inhibition of interferon gamma-activated sequence binding activity

scientific article published on 01 December 2002

Modulation of interleukin-1beta and tumor necrosis factor alpha signaling by P2 purinergic receptors in human fetal astrocytes.

scientific article published on July 2000

Mouse Adenovirus Type-1 Replication Is Restricted to Vascular Endothelium in the CNS of Susceptible Strains of Mice ⬇️

scientific article published on June 5, 1998

Mouse adenovirus type 1 causes a fatal hemorrhagic encephalomyelitis in adult C57BL/6 but not BALB/c mice

scientific article published in December 1995

Multiple Sclerosis: Limited Diversity of the V?2-J?3 T-Cell Receptor in Chronic Active Lesions

Multiple sclerosis: a protective or a pathogenic role for heat shock protein 60 in the central nervous system?

scientific article published on 01 July 1996

Multiple sclerosis: altered expression of 70- and 27-kDa heat shock proteins in lesions and myelin

scientific article published in June 1997

Multiple sclerosis: re-expression of a developmental pathway that restricts oligodendrocyte maturation

scientific article

New possible roles for aquaporin-4 in astrocytes: cell cytoskeleton and functional relationship with connexin43.

scientific article published on 15 August 2005

Nickel induction of Rosenthal fibers in rat brain

scientific article published on 01 April 1981

Non-specific oligodendrocyte cytotoxicity mediated by soluble products of activated T cell lines

scientific article published on December 1991

Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination.

scholarly article

Notes on the pathogenesis of multiple sclerosis

scientific article published in September 1978

Novel synthetic amino acid copolymers that inhibit autoantigen-specific T cell responses and suppress experimental autoimmune encephalomyelitis

scientific article

P2X7 receptors mediate ATP release and amplification of astrocytic intercellular Ca2+ signaling

scientific article published on February 2006

Pathophysiologic effect of interleukin-1b in the rabbit retina

scientific article published on December 1990

Peroxisome proliferator-activated receptor-gamma agonists prevent experimental autoimmune encephalomyelitis

scientific article

Phenotypic and cytokine analysis of human peripheral blood gamma delta T cells expressing NK cell receptors ⬇️

scientific article published on October 15, 1997

Phenotypic and functional properties of γδ T Cells from patients with Guillain Barré syndrome

scientific article published on 01 January 2000

Prazosin treatment during the effector stage of disease suppresses experimental autoimmune encephalomyelitis in the Lewis rat.

scientific article published on December 1986

Prazosin treatment suppresses increased vascular permeability in both acute and passively transferred experimental autoimmune encephalomyelitis in the Lewis rat.

scientific article published on December 1986

Prazosin, an alpha 1-adrenergic receptor antagonist, suppresses experimental autoimmune encephalomyelitis in the Lewis rat.

scientific article published on September 1985

Preliminary studies of cytokine-induced functional effects on the visual pathways in the rabbit

scientific article published on 01 December 1989

Preliminary studies on sensitization of Lewis rats with sulfated glucuronyl paragloboside

scientific article published in February 1991

Preliminary study on the suppression of experimental autoimmune encephalomyelitis in the Lewis rat with spirogermanium

scientific article published on 01 May 1987

Prevention and treatment of experimental autoimmune encephalomyelitis by CNI-1493, a macrophage-deactivating agent ⬇️

scientific article published on June 1, 1998

Productive infection of human fetal microglia in vitro by HIV-1.

scientific article published on October 1993

Proliferation of astrocytes in vitro in response to cytokines. A primary role for tumor necrosis factor

scientific article published on 01 January 1990

Protection against experimental allergic neuritis with silica quartz dust ⬇️

scientific article published on 01 November 1982

Proteinase inhibitors suppress the development of experimental allergic encephalomyelitis ⬇️

scientific article published on May 22, 1980

Quantitation of antigen-specific T-cell-induced demyelination in vitro

scientific article

Quantitative aspects of reactive gliosis: a review

scientific article

Reactive gliosis in the brains of Lewis rats with experimental allergic encephalomyelitis

scientific article published in May 1990

Reactive nitrogen intermediates in human neuropathology: an overview

scientific article published on January 1994

Reciprocal regulation of the junctional proteins claudin-1 and connexin43 by interleukin-1beta in primary human fetal astrocytes

scientific article published on 01 December 2000

Recombinant human lymphokines induce changes in visual evoked potentials in the rabbit

scientific article published on 01 January 1988

Regulation of RANTES/CCL5 expression in human astrocytes by interleukin-1 and interferon-beta

scientific article published in July 2004

Regulation of immune response by P2X7 receptor.

scientific article published on January 2006

Regulation of inducible nitric oxide synthase expression in human glia: implications for inflammatory central nervous system diseases

scientific article published on May 1997

Revisiting Notch in remyelination of multiple sclerosis lesions

scientific article published on January 2009

Role of mitogen-activated protein kinases in inducible nitric oxide synthase and TNFalpha expression in human fetal astrocytes

scientific article published in May 2002

SP-40,40 immunoreactivity in inflammatory CNS lesions displaying astrocyte/oligodendrocyte interactions

scientific article published in March 1993

Selective inhibition of human glial inducible nitric oxide synthase by interferon‐β: Implications for multiple sclerosis ⬇️

scientific article published on 01 March 1998

Studies on demyelination by activated lymphocytes in the rabbit eye. I. Effects of a mononuclear cell infiltrate induced by products of activated lymphocytes ⬇️

scientific article published on June 1, 1977

Studies on demyelination by activated lymphocytes in the rabbit eye. II. Antibody-dependent cell-mediated demyelination ⬇️

scientific article published on June 1, 1977

TGFbeta1 induces Jagged1 expression in astrocytes via ALK5 and Smad3 and regulates the balance between oligodendrocyte progenitor proliferation and differentiation

scientific article

TLR3 and TLR4 are innate antiviral immune receptors in human microglia: role of IRF3 in modulating antiviral and inflammatory response in the CNS.

scientific article

TLR3 ligation activates an antiviral response in human fetal astrocytes: a role for viperin/cig5

scientific article

The 70-kDa heat shock cognate protein (HSC70) is a major constituent of the central nervous system and is up-regulated only at the mRNA level in acute experimental autoimmune encephalomyelitis

scientific article published on 01 October 1993

The TLR3 ligand polyI: C downregulates connexin 43 expression and function in astrocytes by a mechanism involving the NF-kappaB and PI3 kinase pathways

scientific article published in December 2006

The astrocyte in multiple sclerosis revisited ⬇️

scientific article published on January 16, 2013

The cytokine IL-1beta activates IFN response factor 3 in human fetal astrocytes in culture

scientific article

The cytokine IL-1beta transiently enhances P2X7 receptor expression and function in human astrocytes.

scientific article published on January 2005

The effect of gammadelta T cell depletion on cytokine gene expression in experimental allergic encephalomyelitis ⬇️

scientific article published on June 15, 1998

The effect of norepinephrine on endotoxin-mediated macrophage activation

scientific article published on 01 January 1991

The effects of macrophage depletion on the clinical and pathologic expression of experimental allergic encephalomyelitis ⬇️

scientific article published on February 1, 1981

The ordered array of perivascular macrophages is disrupted by IL-1-induced inflammation in the rabbit retina

scientific article published in August 1996

The response of lysosomes in cultured neurons to chlorpromazine ⬇️

scientific article published on 01 July 1970

The suppression of mitogen responses associated with resistance to experimental autoimmune encephalomyelitis requires adherent and T cells ⬇️

scientific article published on May 1, 1984

Toll-like receptors in CNS viral infections

scientific article published on January 2009

Transcriptional profiling of gamma delta T cells identifies a role for vitamin D in the immunoregulation of the V gamma 9V delta 2 response to phosphate-containing ligands

scientific article published in May 2005

Transcriptional profiling of microdissected areas of active multiple sclerosis lesions reveals activation of heat shock protein genes.

scientific article

Tumor Necrosis Factor-Induced Proliferation of Astrocytes from Mature Brain Is Associated with Down-Regulation of Glial Fibrillary Acidic Protein mRNA ⬇️

scientific article published on September 1, 1991

Ultrastructural studies of the blood-retina barrier after exposure to interleukin-1 beta or tumor necrosis factor-alpha.

scientific article

Upregulation of group 1 CD1 antigen presenting molecules in guinea pigs with experimental autoimmune encephalomyelitis: an immunohistochemical study.

scientific article

γδ T Cells Express Activation Markers in the Central Nervous System of Mice with Chronic-relapsing Experimental Autoimmune Encephalomyelitis ⬇️

scientific article published on December 1, 2001

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