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List of works by Emily Ho

3,3'-Diindolylmethane induces G1 arrest and apoptosis in human acute T-cell lymphoblastic leukemia cells

scientific article published in 2012

3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells

scientific article

A miRNA signature for an environmental heterocyclic amine defined by a multi-organ carcinogenicity bioassay in the rat.

scientific article published on 13 March 2017

A role for low-abundance miRNAs in colon cancer: the miR-206/Krüppel-like factor 4 (KLF4) axis ⬇️

scientific article published on September 24, 2012

Absorption and chemopreventive targets of sulforaphane in humans following consumption of broccoli sprouts or a myrosinase-treated broccoli sprout extract.

scientific article

Acetylation of CCAR2 Establishes a BET/BRD9 Acetyl Switch in Response to Combined Deacetylase and Bromodomain Inhibition

scientific article published on 14 January 2019

Analysis of autophagic flux in response to sulforaphane in metastatic prostate cancer cells.

scientific article

Assessment of global proteome in LNCaP cells by 2D-RP/RP LC-MS/MS following sulforaphane exposure.

scientific article

Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.

scientific article

Dietary HDAC inhibitors: time to rethink weak ligands in cancer chemoprevention?

scientific article

Dietary agents as histone deacetylase inhibitors

scientific article

Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates

scientific article published on August 2008

Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells ⬇️

scientific article published on October 26, 2011

Dietary sulforaphane, a histone deacetylase inhibitor for cancer prevention

scientific article

Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells

scientific article published on 4 March 2011

Differential modulation of dibenzo[def,p]chrysene transplacental carcinogenesis: maternal diets rich in indole-3-carbinol versus sulforaphane

scientific article (publication date: July 2013)

Divergent roles of p120-catenin isoforms linked to altered cell viability, proliferation, and invasiveness in carcinogen-induced rat skin tumors

scientific article published on 20 February 2017

Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells

scientific article published on 22 January 2014

Epigenetic Regulation by Sulforaphane: Opportunities for Breast and Prostate Cancer Chemoprevention

scientific article published on April 2015

Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer

scientific article

HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates

scientific article published on 26 April 2013

HDAC6 activity is not required for basal autophagic flux in metastatic prostate cancer cells

scientific article published on 06 December 2015

Histone and Non-Histone Targets of Dietary Deacetylase Inhibitors

scientific article published on 25 August 2015

Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly ⬇️

scientific article published on May 30, 2011

Metabolism and tissue distribution of sulforaphane in Nrf2 knockout and wild-type mice

scientific article

Metabolism as a key to histone deacetylase inhibition

scientific article published on 5 April 2011

MicroRNA profiling of carcinogen‐induced rat colon tumors and the influence of dietary spinach ⬇️

scientific article published on May 29, 2012

MicroRNAs, diet, and cancer: new mechanistic insights on the epigenetic actions of phytochemicals

scientific article

Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: studies with sulforaphane and garlic organosulfur compounds

scientific article published on April 2009

Multi-targeted prevention of cancer by sulforaphane

scientific article

Phytochemicals from cruciferous vegetables, epigenetics, and prostate cancer prevention

scientific article published on 26 June 2013

Promoter de-methylation of cyclin D2 by sulforaphane in prostate cancer cells ⬇️

scientific article published on October 26, 2011

Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells

scientific article published on 9 November 2005

Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice

scientific article

Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects.

scientific article

The epigenome as a potential mediator of cancer and disease prevention in prenatal development

scientific article published on 15 May 2013

The phytochemical 3,3'-diindolylmethane decreases expression of AR-controlled DNA damage repair genes through repressive chromatin modifications and is associated with DNA damage in prostate cancer cells.

scientific article

Untargeted Metabolomic Screen Reveals Changes in Human Plasma Metabolite Profiles Following Consumption of Fresh Broccoli Sprouts.

scientific article published on 28 January 2018

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