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List of works by Katherine M. Brendza

Autoinhibition of Escherichia coli Rep monomer helicase activity by its 2B subdomain

scientific article

Biochemical characterization of tirabrutinib and other irreversible inhibitors of Bruton's tyrosine kinase reveals differences in on - and off - target inhibition

scientific article published on 15 January 2020

Crystal structures of HIV-1 reverse transcriptase with etravirine (TMC125) and rilpivirine (TMC278): implications for drug design

scientific article

Direct binding of ledipasvir to HCV NS5A: mechanism of resistance to an HCV antiviral agent

scientific article published on 9 April 2015

Dithiothreitol causes HIV-1 integrase dimer dissociation while agents interacting with the integrase dimer interface promote dimer formation

scientific article published on 21 February 2011

GS-5806 inhibits pre- to postfusion conformational changes of the respiratory syncytial virus fusion protein

scientific article published on 31 August 2015

Large-scale functional purification of recombinant HIV-1 capsid

scientific article

Lipid-Sensing High-Throughput ApoA-I Assays ⬇️

scientific article published on July 17, 2012

Protein Footprinting and X-ray Crystallography Reveal the Interaction of PD-L1 and a Macrocyclic Peptide

scientific article published on 31 December 2019

RNase H active site inhibitors of human immunodeficiency virus type 1 reverse transcriptase: design, biochemical activity, and structural information

scientific article

The 2B domain of the Escherichia coli Rep protein is not required for DNA helicase activity

scientific article

The HCV non-nucleoside inhibitor Tegobuvir utilizes a novel mechanism of action to inhibit NS5B polymerase function

scientific article

The KN-93 Molecule Inhibits Calcium/Calmodulin-Dependent Protein Kinase II (CaMKII) Activity by Binding to Ca2+/CaM

scientific article published on 10 February 2019

The macroscopic rate of nucleic acid translocation by hepatitis C virus helicase NS3h is dependent on both sugar and base moieties

scientific article published on 06 May 2010

Visualizing ATP-Dependent RNA Translocation by the NS3 Helicase from HCV ⬇️

scientific article published on December 9, 2010

Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex

scientific article

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