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List of works by Zoya N. Demidenko

Accumulation of hypoxia-inducible factor-1alpha is limited by transcription-dependent depletion.

scientific article

Advances in targeting signal transduction pathways

scientific article

At concentrations that inhibit mTOR, resveratrol suppresses cellular senescence.

scientific article published on 21 June 2009

Cellular quiescence caused by the Mdm2 inhibitor nutlin-3A.

scientific article published on 23 November 2009

Chronological lifespan in stationary culture: from yeast to human cells

scientific article published in November 2011

Complementation of two mutant p53: implications for loss of heterozygosity in cancer

scientific article

Contact inhibition and high cell density deactivate the mammalian target of rapamycin pathway, thus suppressing the senescence program

scientific article (publication date: 2 June 2014)

Critical Roles of EGFR Family Members in Breast Cancer and Breast Cancer Stem Cells: Targets for Therapy

scientific article published on 4 March 2016

Cytostatic activity of paclitaxel in coronary artery smooth muscle cells is mediated through transient mitotic arrest followed by permanent post-mitotic arrest: comparison with cancer cells

scientific article published on 17 July 2006

Depletion of mutant p53 and cytotoxicity of histone deacetylase inhibitors

scientific article published on August 2005

Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention

scientific article

Dual mTORC1/C2 inhibitors suppress cellular geroconversion (a senescence program).

scientific article

Dual phosphorylation controls Cdc25 phosphatases and mitotic entry

scientific article

Elimination of proliferating cells unmasks the shift from senescence to quiescence caused by rapamycin

scientific article (publication date: 2011)

Exploring long-term protection of normal human fibroblasts and epithelial cells from chemotherapy in cell culture

scientific article published on March 2011

Flavopiridol induces p53 via initial inhibition of Mdm2 and p21 and, independently of p53, sensitizes apoptosis-reluctant cells to tumor necrosis factor

scientific article published on May 2004

From cytometry to cell cycle: a portrait of Zbigniew Darzynkiewicz.

scientific article

GSK-3 as potential target for therapeutic intervention in cancer

scientific article

Growth stimulation leads to cellular senescence when the cell cycle is blocked

scientific article published on 12 November 2008

Hyper-mitogenic drive coexists with mitotic incompetence in senescent cells

scientific article

Hypoxia suppresses conversion from proliferative arrest to cellular senescence

scientific article

In vitro DNA methylation by wheat nuclear cytosine DNA methyltransferase: effect of phytohormones ⬇️

scientific article published on May 19, 1995

Inhibition of transcription results in accumulation of Wt p53 followed by delayed outburst of p53-inducible proteins: p53 as a sensor of transcriptional integrity.

scientific article published in January 2002

Kinase-addiction and bi-phasic sensitivity-resistance of Bcr-Abl- and Raf-1-expressing cells to imatinib and geldanamycin

scientific article published on 5 April 2005

MEK drives cyclin D1 hyperelevation during geroconversion

scientific article published on 12 July 2013

Mechanism of G1-like arrest by low concentrations of paclitaxel: next cell cycle p53-dependent arrest with sub G1 DNA content mediated by prolonged mitosis

scientific article

Paclitaxel induces primary and postmitotic G1 arrest in human arterial smooth muscle cells.

scientific article published on 24 August 2004

Paradoxical suppression of cellular senescence by p53

scientific article

Pharmacologic inhibition of MEK and PI-3K converges on the mTOR/S6 pathway to decelerate cellular senescence

scientific article

Pharmacological induction of Hsp70 protects apoptosis-prone cells from doxorubicin: comparison with caspase-inhibitor- and cycle-arrest-mediated cytoprotection

scientific article published on 25 November 2005

Phosphorylation of Xenopus Cdc25C at Ser285 Interferes with Ability to Activate a DNA Damage Replication Checkpoint in the Pre-Midblastula Embryos

Phosphorylation of Xenopus Cdc25C at Ser285 interferes with ability to activate a DNA damage replication checkpoint in pre-midblastula embryos

scientific article published in May 2003

Pseudo-DNA damage response in senescent cells

scientific journal article

Quantifying pharmacologic suppression of cellular senescence: prevention of cellular hypertrophy versus preservation of proliferative potential

scientific article

RNA-polymerase, DNA-polymerase, DNA-methyltransferase and sphingomyelinase activities in liver nuclei of rats of different Age

scientific article published on 01 February 1998

Rapamycin decelerates cellular senescence

scientific article

Rapamycin for life: a step to immortality.

scientific article published on 15 December 2011

Rapamycin reverses insulin resistance (IR) in high-glucose medium without causing IR in normoglycemic medium

scientific article published on 8 May 2014

Recent discoveries in the cycling, growing and aging of the p53 field

scientific article published on December 2012

Recent progress in genetics of aging, senescence and longevity: focusing on cancer-related genes

scientific article published on December 2012

Recent progress in targeting cancer

scientific article published on December 2011

Resveratrol potentiates rapamycin to prevent hyperinsulinemia and obesity in male mice on high fat diet

scientific article published on 24 January 2013

S6K in geroconversion

scientific article published on 09 September 2013

Selective killing of adriamycin-resistant (G2 checkpoint-deficient and MRP1-expressing) cancer cells by docetaxel

scientific article published in May 2005

The carboxy terminus of Prospero regulates its subcellular localization

scientific article

The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathway

scientific article published on June 2010

The purpose of the HIF-1/PHD feedback loop: to limit mTOR-induced HIF-1α.

scientific article published on 15 May 2011

The regulation of hypoxic genes by calcium involves c-Jun/AP-1, which cooperates with hypoxia-inducible factor 1 in response to hypoxia

scientific article

p21 (CDKN1A) is a negative regulator of p53 stability.

scientific article

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