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List of works by Henry R. Bourne

A Gsalpha mutant designed to inhibit receptor signaling through Gs.

scientific article

A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity

scientific article

A chemical compass.

scientific article

A mutation that prevents GTP-dependent activation of the alpha chain of Gs.

scientific article published in August 1988

An activation switch in the ligand binding pocket of the C5a receptor

scientific article

Biochemical characterization of three stimulatory GTP-binding proteins. The large and small forms of Gs and the olfactory-specific G-protein, Golf

scientific article published on February 1990

Bound attractant at the leading vs. the trailing edge determines chemotactic prowess

scholarly article

C5a receptor activation. Genetic identification of critical residues in four transmembrane helices

scientific article

Carboxyl terminal domain of Gs alpha specifies coupling of receptors to stimulation of adenylyl cyclase

scientific article published in July 1988

Carboxyl-terminal mutations of Gq alpha and Gs alpha that alter the fidelity of receptor activation

scientific article published in October 1996

Coupling of the alpha 2A-adrenergic receptor to multiple G-proteins. A simple approach for estimating receptor-G-protein coupling efficiency in a transient expression system.

scientific article published in February 1994

Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils

scientific article published in July 2003

Dynamics of a chemoattractant receptor in living neutrophils during chemotaxis

scientific article

Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-gamma and PTEN.

scientific article

G-protein diseases furnish a model for the turn-on switch ⬇️

scientific article published on July 2, 1998

Galphai is not required for chemotaxis mediated by Gi-coupled receptors

scientific article published on January 1999

Gbetagamma and palmitate target newly synthesized Galphaz to the plasma membrane

scientific article published on June 1999

Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis

scientific article

Hormonal stimulation of adenylyl cyclase through Gi-protein beta gamma subunits

scientific article published on March 12, 1992

Identification of receptor contact site involved in receptor-G protein coupling

scientific article published in December 1987

Leukocytes navigate by compass: roles of PI3Kgamma and its lipid products

scientific article

Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils

scientific article published in July 2002

Marriage of the flytrap and the serpent

scientific article published in Nature

Morphology matters in immune cell chemotaxis: membrane asymmetry affects amplification

scientific article published on 25 September 2006

Mutant α subunits of Gi2 inhibit cyclic AMP accumulation ⬇️

scientific article published on May 2, 1991

Neutrophil polarization: spatiotemporal dynamics of RhoA activity support a self-organizing mechanism

scholarly article

Overview of the Alliance for Cellular Signaling

scientific article

Polarization of chemoattractant receptor signaling during neutrophil chemotaxis

scientific article

Potentiation of Gi-mediated phospholipase C activation by retinoic acid in HL-60 cells. Possible role of G gamma 2.

scientific article published on March 1995

Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis

scientific article

Rapid GDP release from Gs alpha in patients with gain and loss of endocrine function

scientific article published on September 1994

Receptor and betagamma binding sites in the alpha subunit of the retinal G protein transducin

scientific article published in January 1997

Receptors induce chemotaxis by releasing the βγ subunit of G i , not by activating G q or G s ⬇️

scientific article published on December 23, 1997

Reciprocal regulation of Gs alpha by palmitate and the beta gamma subunit

scientific article published on December 1996

Recombinant Gq alpha. Mutational activation and coupling to receptors and phospholipase C ⬇️

scientific article published on January 5, 1992

Spatial control of actin polymerization during neutrophil chemotaxis

scientific article

Three adenylate cyclase phenotypes in S49 lymphoma cells produced by mutations of one gene ⬇️

scientific article published on 01 July 1982

Type II adenylylcyclase integrates coincident signals from Gs, Gi, and Gq.

scientific article published on July 1993

Unravelling the signal-transduction network in B lymphocytes

scientific article published in Nature

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