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List of works by Anna Spada

A new structural rearrangement associated to Wolfram syndrome in a child with a partial phenotype

scientific article published on 4 July 2012

A rare S33C mutation of CTNNB1 encoding β-catenin in a parathyroid adenoma found in an Italian primary hyperparathyroid cohort

article

Adequacy of current postglucose GH nadir limit (< 1 µg/l) to define long-lasting remission of acromegalic disease

scientific article published on 8 February 2007

Adrenalectomy reduces the risk of vertebral fractures in patients with monolateral adrenal incidentalomas and subclinical hypercortisolism.

scientific article

An alternate translation initiation site circumvents an amino-terminal DAX1 nonsense mutation leading to a mild form of X-linked adrenal hypoplasia congenita

scientific article

Aryl hydrocarbon receptor-interacting protein and pituitary adenomas: a population-based study on subjects exposed to dioxin after the Seveso, Italy, accident

scientific article published on 11 September 2008

Autosomal dominant pseudohypoparathyroidism type Ib: a novel inherited deletion ablating STX16 causes loss of imprinting at the A/B DMR.

scientific article published on 17 January 2014

Biallelic expression of the Gsalpha gene in human bone and adipose tissue.

scientific article published in December 2004

CDC73 mutations and parafibromin immunohistochemistry in parathyroid tumors: clinical correlations in a single-centre patient cohort

article by Vito Guarnieri et al published 18 September 2012 in Cellular Oncology

Calcimimetic R-568 effects on activity of R990G polymorphism of calcium-sensing receptor.

scientific article published on 3 August 2010

Characterization of intracellular signaling mediated by human somatostatin receptor 5: role of the DRY motif and the third intracellular loop

scientific article published on 02 April 2009

Circulating ghrelin levels in basal conditions and during glucose tolerance test in acromegalic patients

scientific article published in August 2002

Circulating ghrelin levels in celiac patients

scientific article published in November 2003

Circulating levels of ghrelin in human fetuses

scientific article published in August 2003

Clinical characteristics and therapeutic responses in patients with germ-line AIP mutations and pituitary adenomas: an international collaborative study

scientific article published on 4 August 2010

Clinically non-functioning pituitary incidentalomas: characteristics and natural history

scientific article published on 13 September 2019

Comparison between six-year therapy with long-acting somatostatin analogs and successful surgery in acromegaly: effects on cardiovascular risk factors

scientific article published in November 2005

Correction to: Multiple endocrine neoplasia type 1: analysis of germline MEN1 mutations in the Italian multicenter MEN1 patient database

article

Cushing's disease: a prospective case-control study of health-related quality of life and cognitive status before and after surgery

scientific article published on 15 November 2019

Cytoskeleton protein Filamin A is required for efficient Somatostatin receptor type 2 internalization and recycling through Rab5 and Rab4 sorting endosomes in tumor somatotroph cells

scientific article published on 01 October 2019

DAX1 and X-linked adrenal hypoplasia congenita: clinical and molecular analysis in five patients

scientific article published on 01 May 2006

Deciphering the specific role of G(αi/o) isoforms: functional selective oxytocin ligands and somatostatin SST5 receptor mutants

scientific article published on February 2013

Diagnostic features and outcome of surgical therapy of acromegalic patients: experience of the last three decades

scientific article published on January 2014

Different effects of short- and long-term recombinant hGH administration on ghrelin and adiponectin levels in GH-deficient adults

scientific article

Different expression of protein kinase A (PKA) regulatory subunits in normal and neoplastic thyroid tissues

scientific article

Editorial: New strategy to solve the etiopathogenetic conundrum of pituitary adenomas

scientific article published on 01 February 2002

Effect of 9-cis retinoic acid on dopamine D2 receptor expression in pituitary adenoma cells

scientific article

Effect of growth hormone deficiency and recombinant hGH (rhGH) replacement on the hypothalamic?pituitary?adrenal axis in children with idiopathic isolated GH deficiency

scientific article published on 14 September 2007

Effect of recombinant hGH (rhGH) replacement on gonadal function in male patients with organic adult-onset GH deficiency

scientific article published in December 2006

Effect of recombinant human growth hormone (GH) replacement on the hypothalamic-pituitary-adrenal axis in adult GH-deficient patients

scientific article published in November 2004

Estimated glomerular filtration rate by serum cystatin C correlates with cardiometabolic parameters in patients with primary hyperparathyroidism.

scientific article published on 20 July 2015

Evaluation of pituitary function after infectious meningitis in childhood ⬇️

scientific article

Evolution of an aggressive prolactinoma into a growth hormone secreting pituitary tumor coincident with GNAS gene mutation

scientific article published on 4 November 2009

Expression of parathyroid-specific genes in vascular endothelial progenitors of normal and tumoral parathyroid glands

scientific article published on 30 July 2009

Expression of the antiapoptotic gene seladin-1 and octreotide-induced apoptosis in growth hormone-secreting and nonfunctioning pituitary adenomas

scientific article published on 9 August 2005

Expression of the two alternatively spliced PRKAR1A RNAs in human endocrine glands

scientific article published on 01 June 2005

Factors associated with vertebral fracture risk in patients with primary hyperparathyroidism

scientific article published on 25 June 2014

Fibrosis is associated with adiponectin resistance in chronic hepatitis C virus infection

scientific article published on 9 March 2011

Filamin-A is essential for dopamine d2 receptor expression and signaling in tumorous lactotrophs.

scientific article published on 18 January 2012

Filamin-A is required to mediate SST2 effects in pancreatic neuroendocrine tumours.

scientific article published on 5 January 2016

GH replacement improves quality of life and metabolic parameters in cured acromegalic patients with growth hormone deficiency

scientific article published on 17 August 2012

Genetic Analysis and Evaluation of Resistance to Thyrotropin and Growth Hormone-Releasing Hormone in Pseudohypoparathyroidism Type Ib

article by Giovanna Mantovani et al published September 2007 in The Journal of Clinical Endocrinology and Metabolism

Genetics of Pituitary Tumors: Focus on G-Protein Mutations ⬇️

scientific article published on October 1, 2003

Ghrelin and adiponectin in patients with Cushing's disease before and after successful transsphenoidal surgery

scientific article published in January 2005

Gonadal structures in a fetus with complete androgen insensitivity syndrome and persistent Müllerian derivatives: comparison with normal fetal development

scientific article published on 25 October 2010

Growth factors and human pituitary adenomas

scientific article

Growth hormone-releasing hormone resistance in pseudohypoparathyroidism type ia: new evidence for imprinting of the Gs alpha gene.

scientific article published in September 2003

HESX1 expression in human normal pituitaries and pituitary adenomas.

scientific article published on 18 January 2006

High prevalence of AIP gene mutations following focused screening in young patients with sporadic pituitary macroadenomas.

scientific article published on 13 July 2011

Hormonal signaling and pituitary adenomas.

scientific article published on 28 February 2007

Hypercalciuria May Persist After Successful Parathyroid Surgery and It Is Associated With Parathyroid Hyperplasia.

scientific article published on 8 May 2015

Hypogonadotropic hypogonadism as a presenting feature of late-onset X-linked adrenal hypoplasia congenita

scientific article published in January 2002

Hypothalamic-Pituitary Axis in Non-Functioning Pituitary Adenomas: Focus on the Prevalence of Isolated Central Hypoadrenalism

scientific article published on 29 April 2015

Identification of human somatostatin receptor 2 domains involved in internalization and signaling in QGP-1 pancreatic neuroendocrine tumor cell line

scientific article published on 12 July 2016

Immunogenicity, safety and tolerability of inactivated trivalent influenza vaccine in overweight and obese children

scientific article

In postmenopausal female subjects with type 2 diabetes mellitus, vertebral fractures are independently associated with cortisol secretion and sensitivity

scientific article published on 15 January 2015

Increased prevalence of the GCM2 polymorphism, Y282D, in primary hyperparathyroidism: analysis of three Italian cohorts

scientific article

Influence of the d3GH receptor polymorphism on the metabolic and biochemical phenotype of GH-deficient adults at baseline and during short- and long-term recombinant human GH replacement therapy

scientific article published on 30 June 2010

Is the 250 μg ACTH test a useful tool for the diagnosis of central hypoadrenalism in adult patients with pituitary disorders?

scientific article

Landscape of somatic mutations in sporadic GH-secreting pituitary adenomas.

scientific article published on 23 December 2015

Long-term effects of radiotherapy on cardiovascular risk factors in acromegaly

scientific article published in May 2011

Long-term evaluation of postoperative acromegalic patients in remission with previous and newly proposed criteria

scientific article published on 7 December 2004

MEN1-related hyperparathyroidism: response to cinacalcet and its relationship with the calcium-sensing receptor gene variant Arg990Gly

scientific article published on 10 May 2012

MON-465 SST2 Trafficking Through The Cytoskeleton: Role Of Scaffolding Proteins Filamin A And β-arrestin 2.

scientific article published on 30 April 2019

Maternal and foetal resistin and adiponectin concentrations in normal and complicated pregnancies

scientific article published on 01 March 2007

Mechanisms of disease: Mutations of G proteins and G-protein-coupled receptors in endocrine diseases.

scientific article published on December 2006

Mosaicism for GNAS methylation defects associated with pseudohypoparathyroidism type 1B arose in early post-zygotic phases

scientific article published on 6 February 2018

Multiple endocrine neoplasia syndrome type 1: institution, management, and data analysis of a nationwide multicenter patient database

scientific article

Multiple endocrine neoplasia type 1: analysis of germline MEN1 mutations in the Italian multicenter MEN1 patient database

article

Non-functioning pituitary adenoma database: a useful resource to improve the clinical management of pituitary tumors

scientific article published in December 2006

PKA regulatory subunit R2B is required for murine and human adipocyte differentiation

scientific article

Parental origin of Gsalpha mutations in the McCune-Albright syndrome and in isolated endocrine tumors

scientific article published in June 2004

Pathogenesis of prolactinomas.

scientific article

Polymorphisms at the regulatory regions of the CASR gene influence stone risk in primary hyperparathyroidism

article

Prediction of Vertebral Fractures in Patients With Monolateral Adrenal Incidentalomas

scientific article published on 04 May 2016

Preliminary data on biochemical remission of acromegaly after somatostatin analogs withdrawal

scientific article

Proliferation of transformed somatotroph cells related to low or absent expression of protein kinase a regulatory subunit 1A protein.

scientific article published in December 2004

Prompt clinical and biochemical response to denosumab in a young adult patient with craniofacial fibrous dysplasia

scientific article published on September 2016

Protein kinase A regulatory subunits in human adipose tissue: decreased R2B expression and activity in adipocytes from obese subjects

scientific article published on 18 December 2008

Pseudohypoparathyroidism and Gsα-cAMP-linked disorders: current view and open issues.

scientific article published on 22 April 2016

Pseudohypoparathyroidism andGNASEpigenetic Defects: Clinical Evaluation of Albright Hereditary Osteodystrophy and Molecular Analysis in 40 Patients

article

Pseudohypoparathyroidism type Ia and pseudo-pseudohypoparathyroidism: the growing spectrum of GNAS inactivating mutations

scientific article published on 18 January 2013

Quantitative analysis of methylation defects and correlation with clinical characteristics in patients with pseudohypoparathyroidism type I and GNAS epigenetic alterations.

scientific article published in January 2013

Recombinant human GH replacement therapy in children with pseudohypoparathyroidism type Ia: first study on the effect on growth

scientific article published on 18 August 2010

Reevaluation of Acromegalic Patients in Long-Term Remission according to Newly Proposed Consensus Criteria for Control of Disease

scientific article

Resistance to growth hormone releasing hormone and gonadotropins in Albright's hereditary osteodystrophy

scientific article published on May 2006

Risk of nephrolithiasis in primary hyperparathyroidism is associated with two polymorphisms of the calcium-sensing receptor gene

article

Role of IGF1-(CA)19 promoter microsatellite in the clinical presentation of acromegaly

scientific article

SAT-566 Cofilin Is a Mediator of RET-Promoted Medullary Thyroid Carcinoma Cell Migration, Invasion and Proliferation

Screening of PRKAR1A and PDE4D in a Large Italian Series of Patients Clinically Diagnosed With Albright Hereditary Osteodystrophy and/or Pseudohypoparathyroidism

scientific article

Serum activin A levels in different thyroid disorders

scientific article published in December 2002

Severe water intoxication secondary to the concomitant intake of non-steroidal anti-inflammatory drugs and desmopressin: a case report and review of the literature ⬇️

scientific article published on January 1, 2013

Single-Molecule Microscopy Reveals Dynamic FLNA Interactions Governing SSTR2 Clustering and Internalization

scientific article published on 01 August 2018

Somatic mutational analysis of DAX1 in testes from men with idiopathic azoospermia

scientific article published in November 2005

Somatostatin analogs regulate tumor corticotrophs growth by reducing ERK1/2 activity

scientific article published on 03 January 2019

Somatostatin analogues increase AIP expression in somatotropinomas, irrespective of Gsp mutations.

scientific article published on 16 September 2013

Specific roles of G(i) protein family members revealed by dissecting SST5 coupling in human pituitary cells

scientific article

Specific roles of Giprotein family members revealed by dissecting SST5 coupling in human pituitary cells

scientific article published in 2014

Sporadic and MEN1-related primary hyperparathyroidism: differences in clinical expression and severity

scientific article published in August 2009

Stem Cells in Pituitary Tumors: Experimental Evidence Supporting Their Existence and Their Role in Tumor Clinical Behavior

scientific article published on 25 October 2019

Suppressive effects of tenofovir disoproxil fumarate, an antiretroviral prodrug, on mineralization and type II and type III sodium-dependent phosphate transporters expression in primary human osteoblasts

scientific article published on 24 January 2018

The activity of 11β-hydroxysteroid dehydrogenase type 2 enzyme and cortisol secretion in patients with adrenal incidentalomas

scientific article published in September 2016

The activity of 11β-hydroxysteroid dehydrogenase type 2 enzyme and cortisol secretion in patients with adrenal incidentalomas

scholarly article by Valentina Morelli et al published 5 October 2015 in Endocrine

The dopamine-somatostatin chimeric compound BIM-23A760 exerts antiproliferative and cytotoxic effects in human non-functioning pituitary tumors by activating ERK1/2 and p38 pathways.

scientific article published on 19 July 2009

The gsalpha gene: predominant maternal origin of transcription in human thyroid gland and gonads

scientific article published in October 2002

The microRNA cluster C19MC is deregulated in parathyroid tumours.

scientific article published on 26 July 2012

The third intracellular loop of the human somatostatin receptor 5 is crucial for arrestin binding and receptor internalization after somatostatin stimulation

scientific article published on 20 December 2007

Thyrotropin-secreting pituitary adenomas: outcome of pituitary surgery and irradiation

scientific article published on 19 February 2014

Trabecular Bone Score (TBS) and Bone Metabolism in Patients Affected with Type 1 Neurofibromatosis (NF1)

scientific article published on 12 November 2018

Vitamin D and skeletal health in autoimmune bullous skin diseases: a case control study

scientific article

cAMP in the pituitary: an old messenger for multiple signals.

scientific article

cAMP pathway and pituitary tumorigenesis.

scientific article published on 22 April 2012

d3-Growth hormone receptor polymorphism in acromegaly: effects on metabolic phenotype

scientific article published in May 2010

β-arrestin 2 is required for dopamine receptor type 2 inhibitory effects on AKT phosphorylation and cell proliferation in pituitary tumors

scientific article published on 08 June 2020

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