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List of works by James K. Liao

1alpha,25-dihydroxyvitamin D3 induces vascular smooth muscle cell migration via activation of phosphatidylinositol 3-kinase

scientific article

A Mouse Model of Diet-Induced Obesity and Insulin Resistance ⬇️

scientific article published on January 1, 2012

Absence of TRAM restricts Toll-like receptor 4 signaling in vascular endothelial cells to the MyD88 pathway

scientific article published on 30 March 2006

Activation of the phosphatidylinositol 3-kinase/protein kinase Akt pathway mediates nitric oxide-induced endothelial cell migration and angiogenesis

scientific article

Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase

scientific article

Acute reduction of myocardial infarct size by a hydroxymethyl glutaryl coenzyme A reductase inhibitor is mediated by endothelial nitric oxide synthase

scientific article published in March 2003

Calcium channel blocker and Rho-associated kinase activity in patients with hypertension

scientific article published on February 2011

Comparison of effects of rosuvastatin (10 mg) versus atorvastatin (40 mg) on rho kinase activity in caucasian men with a previous atherosclerotic event

scientific article published on 25 December 2008

Critical role of endothelial Notch1 signaling in postnatal angiogenesis.

scientific article published on 7 December 2006

Decreased perivascular fibrosis but not cardiac hypertrophy in ROCK1+/- haploinsufficient mice

scientific article published on 31 October 2005

Decreased vascular lesion formation in mice with inducible endothelial-specific expression of protein kinase Akt

scientific article

Deficiency of ROCK1 in bone marrow-derived cells protects against atherosclerosis in LDLR-/- mice

scientific article published on 12 June 2008

Dynamic regulation of endothelial NOS mediated by competitive interaction with alpha-actinin-4 and calmodulin

scientific article published on 7 January 2008

Endothelial function and oxidative stress

scientific article published in March 2004

Endothelium-dependent effects of statins

scientific article

Eplerenone improves endothelial function and arterial stiffness and inhibits Rho-associated kinase activity in patients with idiopathic hyperaldosteronism: a pilot study

Essential role of endothelial Notch1 in angiogenesis

scientific journal article

Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation

scientific article published on 15 December 2008

Evidence of pleiotropy by statins: leukocyte Rho kinase (ROCK) activity and pretreated statin before percutaneous coronary interventions are clinical vascular outcome predictors.

scientific article published on 6 July 2014

FHL2 prevents cardiac hypertrophy in mice with cardiac‐specific deletion of ROCK2 ⬇️

scientific article published on December 27, 2012

Increased leukocyte ROCK activity in patients after acute ischemic stroke

scientific article published on 25 December 2008

Increased leukocyte rho kinase (ROCK) activity and endothelial dysfunction in cigarette smokers

scientific article

Increased vascular senescence and impaired endothelial progenitor cell function mediated by mutation of circadian gene Per2.

scientific article

Induction of angiogenesis by heat shock protein 90 mediated by protein kinase Akt and endothelial nitric oxide synthase

scientific article published on 14 October 2004

Inhibition of Rho kinase (ROCK) leads to increased cerebral blood flow and stroke protection

scientific article published on September 2005

Inhibition of apoptosis-regulated signaling kinase-1 and prevention of congestive heart failure by estrogen

scientific article published on 11 June 2007

Linking Notch signaling to ischemic stroke

scholarly article

Measurement of Rho-associated kinase (ROCK) activity in humans: validity of leukocyte p-MBS/t-MBS in comparison with vascular response to fasudil

scientific article published on 12 October 2010

Molecular basis of cell membrane estrogen receptor interaction with phosphatidylinositol 3-kinase in endothelial cells

scientific article published on February 2003

Neuroprotection Mediated by Upregulation of Endothelial Nitric Oxide Synthase in Rho-Associated, Coiled-Coil-Containing Kinase 2 Deficient Mice

scientific article

Nongenomic mechanisms of endothelial nitric oxide synthase activation by the selective estrogen receptor modulator raloxifene

scientific article published in March 2002

Nontranscriptional actions of the glucocorticoid receptor.

scientific article

Notch Signaling as an Important Mediator of Cardiac Repair and Regeneration After Myocardial Infarction ⬇️

scientific article published on October 1, 2010

Notch signaling regulates endothelial progenitor cell activity during recovery from arterial injury in hypercholesterolemic mice

scientific article published on 22 February 2010

Notch1 in Bone Marrow–Derived Cells Mediates Cardiac Repair After Myocardial Infarction ⬇️

scientific article published on February 14, 2011

Novel aspects of the roles of Rac1 GTPase in the cardiovascular system

scientific article

Novel non-transcriptional mechanisms for estrogen receptor signaling in the cardiovascular system

scholarly article by Tommaso Simoncini et al published November 2002 in Steroids

Novel non-transcriptional mechanisms for estrogen receptor signaling in the cardiovascular system. Interaction of estrogen receptor alpha with phosphatidylinositol 3-OH kinase

scientific article (publication date: November 2002)

Obesity increases vascular senescence and susceptibility to ischemic injury through chronic activation of Akt and mTOR.

scientific article published on 17 March 2009

Phosphatidylinositol 3-kinase/protein kinase Akt negatively regulates plasminogen activator inhibitor type 1 expression in vascular endothelial cells.

scientific article published on 15 December 2006

Physiological role of ROCKs in the cardiovascular system

scientific article

Pitavastatin-induced angiogenesis and arteriogenesis is mediated by Notch1 in a murine hindlimb ischemia model without induction of VEGF.

scientific article published on 07 February 2011

Pleiotropic effects of statin therapy: molecular mechanisms and clinical results.

scientific article published on January 2008

Pleiotropic effects of statins. - Basic research and clinical perspectives -.

scientific article published on 15 April 2010, Circulation Journal

Protective effects of statins involving both eNOS and tPA in focal cerebral ischemia

scientific article published on June 2005

ROCK1 mediates leukocyte recruitment and neointima formation following vascular injury

scientific article published on May 2008

Rac1 is a critical mediator of endothelium-derived neurotrophic activity

scientific article published on 10 March 2009

Rapid nongenomic actions of thyroid hormone.

scholarly article

Rapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids

Rapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids.

scientific article

Regulation of endothelial nitric oxide synthase and postnatal angiogenesis by Rac1.

scientific article published on 03 July 2008

Requirement of Rac1 in the development of cardiac hypertrophy.

scholarly article

Rho GTPases, statins, and nitric oxide

scientific article

Rho kinase inhibition improves endothelial function in human subjects with coronary artery disease

scientific article

Rho-associated kinase activity, endothelial function, and cardiovascular risk factors

scientific article published on 07 July 2011

Rho-kinase inhibition acutely augments blood flow in focal cerebral ischemia via endothelial mechanisms

scientific article

Rho-kinase mediates hyperglycemia-induced plasminogen activator inhibitor-1 expression in vascular endothelial cells

scientific article published on 13 June 2005

Rho/Rho-associated coiled-coil forming kinase pathway as therapeutic targets for statins in atherosclerosis

scientific article

RhoA/ROCK signaling is essential for multiple aspects of VEGF-mediated angiogenesis.

scientific article

Roles of rho-associated kinase and oxidative stress in the pathogenesis of aortic stiffness

scientific article published on 26 January 2007

Smooth muscle Notch1 mediates neointimal formation after vascular injury

scientific article published on 11 May 2009

Statins inhibit Rho kinase activity in patients with atherosclerosis

scientific article published on 24 December 2008

Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis ⬇️

scientific article published on March 29, 2011

Targeting eNOS and beyond: emerging heterogeneity of the role of endothelial Rho proteins in stroke protection

scientific article

Transcription factor CHF1/Hey2 suppresses cardiac hypertrophy through an inhibitory interaction with GATA4

scientific journal article

Translational therapeutics of dipyridamole

scientific article published on 03 January 2008

Vascular protection by estrogen in ischemia-reperfusion injury requires endothelial nitric oxide synthase

scientific article

gamma-Secretase inhibitor reduces diet-induced atherosclerosis in apolipoprotein E-deficient mice.

scientific article published on 5 April 2009

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