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List of works by Robyn M. Sutherland

Adult Pancreas Side Population Cells Expand after β Cell Injury and Are a Source of Insulin-Secreting Cells ⬇️

scientific article published on November 9, 2012

Anti-CD2 producing pig xenografts effect localized depletion of human T cells in a huSCID model

scientific article

Anti-CD45RB antibody deters xenograft rejection by modulating T cell priming and homing.

scientific article published in August 2002

Anti-apoptotic proteins BCL-2, MCL-1 and A1 summate collectively to maintain survival of immune cell populations both in vitro and in vivo.

scientific article published on 31 March 2017

Antigen affinity, costimulation, and cytokine inputs sum linearly to amplify T cell expansion

scientific article published in Science

BH3 mimetics antagonizing restricted prosurvival Bcl-2 proteins represent another class of selective immune modulatory drugs

scientific article

Bcl-2 protection of islet allografts is unmasked by costimulation blockade

scientific article published in May 2004

Cognate antigen engagement on parenchymal cells stimulates CD8+ T cell proliferation in situ

scientific article

Constitutive, but not inflammatory, cross-presentation is disabled in the pancreas of young mice

article

Constitutive, but not inflammatory, cross-presentation is disabled in the pancreas of young mice

scientific article published on 01 April 2002

Cytotoxic T-Cells From T-Cell Receptor Transgenic NOD8.3 Mice Destroy β-Cells via the Perforin and Fas Pathways

scientific article published on 01 September 2006

Effector-memory T cells develop in islets and report islet pathology in type 1 diabetes

scientific article published on 11 December 2013

Endocrine cells develop within pancreatic bud-like structures derived from mouse ES cells differentiated in response to BMP4 and retinoic acid

scientific article published on 3 August 2007

Evaluation of promoters for driving efficient transgene expression in neonatal porcine islets.

scientific article published on March 2007

Functional cytotoxic T lymphocytes against IGRP206-214 predict diabetes in the non-obese diabetic mouse.

scientific article published on 29 April 2014

Heterogeneity, functional specialization and differentiation of monocyte-derived dendritic cells.

scientific article

In situ protection against islet allograft rejection by CTLA4Ig transduction

scientific article published on November 2010

Influenza-induced, helper-independent CD8+ T cell responses use CD40 costimulation at the late phase of the primary response

scientific article published on 29 October 2012

Innate Allorecognition Results in Rapid Accumulation of Monocyte-Derived Dendritic Cells.

scientific article published on 29 July 2016

Monocyte-Derived Dendritic Cells Impair Early Graft Function Following Allogeneic Islet Transplantation.

scientific article published on 13 October 2016

Monocyte-Derived Dendritic Cells Promote Th Polarization, whereas Conventional Dendritic Cells Promote Th Proliferation.

scientific article

Optimizing transduction of pig islet cell clusters for xenotransplantation.

scientific article published in January 2009

Pathogenic Mechanisms in Type 1 Diabetes: The Islet is Both Target and Driver of Disease ⬇️

scientific article published on December 28, 2012

Preclinical screening for acute toxicity of therapeutic monoclonal antibodies in a hu-SCID model.

scientific article

Prolonged local expression of anti-CD4 antibody by adenovirally transduced allografts can promote long-term graft survival

scientific article published in January 2006

Prosurvival Bcl-2 family members reveal a distinct apoptotic identity between conventional and plasmacytoid dendritic cells

scientific article

Repurposed JAK1/JAK2 Inhibitor Reverses Established Autoimmune Insulitis in NOD Mice.

scientific article published on 14 March 2017

Selected Toll-like receptor ligands and viruses promote helper-independent cytotoxic T cell priming by upregulating CD40L on dendritic cells

scientific article published on 05 February 2009

Selective Depletion of Cross-Presenting Dendritic Cells Enhances Islet Allograft Survival

scientific article published on 30 September 2010

Targeting CD45RB alters T cell migration and delays viral clearance.

scientific article published on 16 December 2005

The closely related CD103+ dendritic cells (DCs) and lymphoid-resident CD8+ DCs differ in their inflammatory functions

scientific article

The linear range for accurately quantifying antigen-specific T-cell frequencies by tetramer staining during natural immune responses

scientific article published on 11 April 2011

The non-immune RIP-Kb mouse is a useful host for islet transplantation, as the diabetes is spontaneous, mild and predictable

scientific article published on January 2002

Tissue destruction caused by cytotoxic T lymphocytes induces deletional tolerance

scholarly article

Unlike CD4+ T-cell help, CD28 costimulation is necessary for effective primary CD8+ T-cell influenza-specific immunity

scientific article published on 14 June 2012

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