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List of works by Saara Laitinen

A cytosolic splice variant of Cab45 interacts with Munc18b and impacts on amylase secretion by pancreatic acini

scientific article

A robust and reproducible animal serum-free culture method for clinical-grade bone marrow-derived mesenchymal stromal cells

scientific article published on 17 March 2015

Adenosinergic Immunosuppression by Human Mesenchymal Stromal Cells Requires Co-Operation with T cells

scientific article published on 5 January 2016

Aging bone marrow mesenchymal stromal cells have altered membrane glycerophospholipid composition and functionality

scientific article published on 27 December 2012

Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper.

scientific article

Are globoseries glycosphingolipids SSEA-3 and -4 markers for stem cells derived from human umbilical cord blood? ⬇️

scientific article published on December 12, 2010

Assessment of Time-Dependent Platelet Activation Using Extracellular Vesicles, CD62P Exposure, and Soluble Glycoprotein V Content of Platelet Concentrates with Two Different Platelet Additive Solutions

scientific article published on 07 May 2019

Biological properties of extracellular vesicles and their physiological functions.

scientific article published on 14 May 2015

CD200 positive human mesenchymal stem cells suppress TNF-alpha secretion from CD200 receptor positive macrophage-like cells

scientific article

Cell surface structures influence lung clearance rate of systemically infused mesenchymal stromal cells

scientific article published on February 2013

Chlamydial and periodontal pathogens induce hepatic inflammation and fatty acid imbalance in apolipoprotein E-deficient mice

scientific article published on 18 May 2009

Circulating plastic adherent mesenchymal stem cells in aged hip fracture patients

scientific article published on 01 December 2010

Detection and quantification of five major periodontal pathogens by single copy gene-based real-time PCR.

scientific article

Differential Clearance of Rat and Human Bone Marrow-Derived Mesenchymal Stem Cells from the Brain after Intra-arterial Infusion in Rats

scientific article published on 03 March 2014

Expansion induced microRNA changes in bone marrow mesenchymal stromal cells reveals interplay between immune regulation and cell cycle.

scientific article published on 9 November 2016

Expression of the novel Golgi protein GoPro49 is developmentally regulated during mesenchymal differentiation

scientific article

Extracellular membrane vesicles from umbilical cord blood-derived MSC protect against ischemic acute kidney injury, a feature that is lost after inflammatory conditioning

scientific article published on 10 December 2013

Extracellular o-linked N-acetylglucosamine is enriched in stem cells derived from human umbilical cord blood

scientific article

Gene expression in human NAFLD.

scientific article

HIF-1α is upregulated in human mesenchymal stem cells

scientific article published in September 2013

Human Mesenchymal Stromal Cell Secretome Promotes the Immunoregulatory Phenotype and Phagocytosis Activity in Human Macrophages

scientific article published on 22 September 2020

Inhibition of adipocyte differentiation by RORalpha.

scientific article published on 18 May 2009

Isolation and characterization of platelet-derived extracellular vesicles

scientific article

Label-free characterization and real-time monitoring of cell uptake of extracellular vesicles

scientific article published on 15 August 2020

Lipid mediators in platelet concentrate and extracellular vesicles: Molecular mechanisms from membrane glycerophospholipids to bioactive molecules

scientific article published on 10 April 2019

Low oxygen tension reveals distinct HOX codes in human cord blood-derived stromal cells associated with specific endochondral ossification capacities in vitro and in vivo

scientific article

Mesenchymal Stromal Cells and Their Extracellular Vesicles Enhance the Anti-Inflammatory Phenotype of Regulatory Macrophages by Downregulating the Production of Interleukin (IL)-23 and IL-22.

scientific article published on 12 April 2018

Metabolic glycoengineering of mesenchymal stromal cells with N-propanoylmannosamine

scientific article published on 25 May 2013

Metabolism and phospholipid assembly of polyunsaturated fatty acids in human bone marrow mesenchymal stromal cells.

scientific article published on 16 November 2016

Metabolomic Profiling of Extracellular Vesicles and Alternative Normalization Methods Reveal Enriched Metabolites and Strategies to Study Prostate Cancer-Related Changes

scientific article published on 23 August 2017

Methylome Analysis of Human Bone Marrow MSCs Reveals Extensive Age- and Culture-Induced Changes at Distal Regulatory Elements.

scientific article

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

scientific article published on 23 November 2018

Mitochondrial function and energy metabolism in umbilical cord blood- and bone marrow-derived mesenchymal stem cells.

scientific article published on 20 July 2011

ORP2, a homolog of oxysterol binding protein, regulates cellular cholesterol metabolism

scientific article

Overexpression of OSBP-related protein 2 (ORP2) in CHO cells induces alterations of phospholipid species composition

scientific article published in October 2005

Overexpression of OSBP-related protein 2 (ORP2) induces changes in cellular cholesterol metabolism and enhances endocytosis.

scientific article

Phospholipid composition of packed red blood cells and that of extracellular vesicles show a high resemblance and stability during storage.

scientific article

Polyunsaturated fatty acids modify the extracellular vesicle membranes and increase the production of proresolving lipid mediators of human mesenchymal stromal cells

scientific article published on 15 June 2019

Potential roles of ROR-alpha in cardiovascular endocrinology

scientific article

Production of a recombinant antibody specific for i blood group antigen, a mesenchymal stem cell marker

scientific article

Real-Time Label-Free Monitoring of Nanoparticle Cell Uptake

scientific article published on 30 September 2016

Tenascin-C and fibronectin expression divide early stage tongue cancer into low- and high-risk groups

scientific article published on 17 January 2017

The effect of proatherogenic pathogens on adipose tissue transcriptome and fatty acid distribution in apolipoprotein E-deficient mice

scientific article

The effects of culture conditions on the functionality of efficiently obtained mesenchymal stromal cells from human cord blood

scientific article

The i Blood Group Antigen as a Marker for Umbilical Cord Blood-Derived Mesenchymal Stem Cells ⬇️

scientific article published on November 2, 2011

The isolation and culture of human cord blood-derived mesenchymal stem cells under low oxygen conditions.

scientific article published in January 2011

Transcriptome teleonomy and scavenger lipidomics of albumin and alpha 1-acid glycoproteins: contextual genome-wide ontology enrichment as evidence for the epigenetic code?

Transient proteolytic modification of mesenchymal stromal cells increases lung clearance rate and targeting to injured tissue

scientific article published on 03 June 2013

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