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List of works by Henk M. Lokhorst

A Rational Strategy for Reducing On-Target Off-Tumor Effects of CD38-Chimeric Antigen Receptors by Affinity Optimization.

scientific article published on 13 May 2017

A bioluminescence imaging based in vivo model for preclinical testing of novel cellular immunotherapy strategies to improve the graft-versus-myeloma effect.

scientific article

A class II-restricted cytotoxic T-cell clone recognizes a human minor histocompatibility antigen with a restricted tissue distribution.

scientific article

A clinical update on the role of carfilzomib in the treatment of relapsed or refractory multiple myeloma

scientific article

A cost-utility analysis comparing intensive chemotherapy alone to intensive chemotherapy followed by myeloablative chemotherapy with autologous stem-cell rescue in newly diagnosed patients with stage II/III multiple myeloma; a prospective randomised

scientific article published on 01 May 2004

A gene expression signature for high-risk multiple myeloma.

scientific article published on 8 May 2012

A novel CBFA2 single-nucleotide mutation in familial platelet disorder with propensity to develop myeloid malignancies.

scientific article published in November 2001

A novel flow cytometric assay for the quantification of adhesion of subsets within a heterogeneous cell population; analysis of lymphocyte function-associated antigen-1 (LFA-1)-mediated binding of bone marrow-derived primary tumour cells of patients

scientific article published on 01 September 1993

A phase I/II minor histocompatibility antigen-loaded dendritic cell vaccination trial to safely improve the efficacy of donor lymphocyte infusions in myeloma

scientific article published on 05 June 2017

A randomized phase 3 study on the effect of thalidomide combined with adriamycin, dexamethasone, and high-dose melphalan, followed by thalidomide maintenance in patients with multiple myeloma

scientific article published on 30 October 2009

Abnormalities of chromosome 1p/q are highly associated with chromosome 13/13q deletions and are an adverse prognostic factor for the outcome of high-dose chemotherapy in patients with multiple myeloma

scientific article published on 01 February 2007

Absence of intraocular infections after hematopoietic stem cell transplantation at a single center: the experience with current preventive regimens

scientific article published on 8 October 2013

Accessory cells of the microenvironment protect multiple myeloma from T-cell cytotoxicity through cell adhesion-mediated immune resistance.

scientific article published on 4 September 2013

Administration of bortezomib before and after autologous stem cell transplantation improves outcome in multiple myeloma patients with deletion 17p

scientific article published on 08 December 2011

Advances in the treatment of multiple myeloma

scientific article

Allogeneic and syngeneic hematopoietic cell transplantation in patients with amyloid light-chain amyloidosis: a report from the European Group for Blood and Marrow Transplantation.

scientific article

Allogeneic bone marrow transplantation with a fixed low number of T cells in the marrow graft

scientific article published on 01 May 1994

Allogeneic versus autologous bone marrow transplantation for refractory and recurrent low-grade non-Hodgkin's lymphoma ⬇️

scientific article published on November 15, 1997

Altered peptide ligands revisited: vaccine design through chemically modified HLA-A2-restricted T cell epitopes

scientific article published on 13 October 2014

Analysis of efficacy and prognostic factors of lenalidomide treatment as part of a Dutch compassionate use program

scientific article published in April 2010

Analysis of efficacy and toxicity of thalidomide in 122 patients with multiple myeloma: response of soft-tissue plasmacytomas

scientific article published in January 2005

Analysis of multidrug‐resistance (MDR‐1) glycoprotein and CD56 expression to separate monoclonal gammopathy from multiple myeloma ⬇️

scientific article published on January 1, 1993

Analysis of the efficacy and toxicity of bortezomib for treatment of relapsed or refractory multiple myeloma in community practice.

scientific article published in July 2005

Antigens shared by malignant plasma cells and normal B cells may be involved in graft versus myeloma

scientific article published on February 2003

Anti‐adhesive signals are mediated via major histocompatibility complex class II molecules in normal and neoplastic human B cells: Correlation with B cell differentiation stage ⬇️

scientific article published on October 1, 1997

Autologous bone marrow transplantation for adult poor-risk lymphoblastic lymphoma in first remission ⬇️

scientific article published on 01 April 1992

Blocking interleukin-6 activity with chimeric anti-IL6 monoclonal antibodies in multiple myeloma: effects on soluble IL6 receptor and soluble gp130

scientific article published on 01 November 1998

Bortezomib before and after autologous stem cell transplantation overcomes the negative prognostic impact of renal impairment in newly diagnosed multiple myeloma: a subgroup analysis from the HOVON-65/GMMG-HD4 trial

scientific article

Bortezomib before and after high-dose therapy in myeloma: long-term results from the phase III HOVON-65/GMMG-HD4 trial.

scientific article

Bortezomib induction and maintenance treatment in patients with newly diagnosed multiple myeloma: results of the randomized phase III HOVON-65/ GMMG-HD4 trial

scientific article published on 16 July 2012

Bortezomib-based versus nonbortezomib-based induction treatment before autologous stem-cell transplantation in patients with previously untreated multiple myeloma: a meta-analysis of phase III randomized, controlled trials

scientific article

CD38 expression and complement inhibitors affect response and resistance to daratumumab therapy in myeloma

scientific article published on 15 June 2016

CD38-targeting antibodies in multiple myeloma: mechanisms of action and clinical experience

scientific article published on 21 February 2018

CD44 isoforms are differentially regulated in plasma cell dyscrasias and CD44v9 represents a new independent prognostic parameter in multiple myeloma ⬇️

scientific article published on 01 December 2001

CD44 isoforms distinguish between bone marrow plasma cells from normal individuals and patients with multiple myeloma at different stages of disease

scientific article published on 01 November 1998

CD44 variant isoforms are involved in plasma cell adhesion to bone marrow stromal cells

scientific article published on 01 January 2002

Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients

scientific article published on 15 March 2018

Chemosensitization of myeloma plasma cells by an antisense-mediated downregulation of Bcl-2 protein

scientific article published in January 2003

Chimaeric anti‐interleukin 6 monoclonal antibodies in the treatment of advanced multiple myeloma: a phase I dose‐escalating study ⬇️

scientific article published on August 1, 1998

Chronic idiopathic axonal polyneuropathy. Comparison of patients with and without monoclonal gammopathy

scientific article published in April 1996

Clinical efficacy and management of monoclonal antibodies targeting CD38 and SLAMF7 in multiple myeloma.

scientific article

Clinical efficacy of daratumumab monotherapy in patients with heavily pretreated relapsed or refractory multiple myeloma

scientific article published on 23 May 2016

Clinical judgment and decision making in medical practice. A retiree with fatigue and foot drop

scientific article published on January 24, 1998

Combination of international scoring system 3, high lactate dehydrogenase, and t(4;14) and/or del(17p) identifies patients with multiple myeloma (MM) treated with front-line autologous stem-cell transplantation at high risk of early MM progression-r

scientific article

Combined CD28 and 4-1BB Costimulation Potentiates Affinity-tuned Chimeric Antigen Receptor-engineered T Cells

scientific article published on 12 April 2019

Comparison of intramedullary myeloma and corresponding extramedullary soft tissue plasmacytomas using genetic mutational panel analyses

scientific article published on 20 May 2016

Comparison of plasma cell infiltration in bone marrow biopsies and aspirates in patients with multiple myeloma

scientific article published on 01 September 1992

Complement activation on B lymphocytes opsonized with rituximab or ofatumumab produces substantial changes in membrane structure preceding cell lysis

scientific article

Consensus Conference on Salvage Hematopoietic Cell Transplantation in Patients with Relapsed Multiple Myeloma (short title)

scientific article

Consensus strategy to quantitate malignant cells in myeloma patients is validated in a multicenter study. Belgium-Dutch Hematology-Oncology Group

scientific article published on 01 July 2000

Continuous low-dose cyclophosphamide-prednisone is effective and well tolerated in patients with advanced multiple myeloma

scientific article published in August 2001

Correlation of high-resolution X-ray micro-computed tomography with bioluminescence imaging of multiple myeloma growth in a xenograft mouse model

scientific article published on 9 October 2009

Current and New Therapeutic Strategies for Relapsed and Refractory Multiple Myeloma: An Update.

scientific article published on 29 November 2017

Cyclosporin A combined with vincristine, doxorubicin and dexamethasone (VAD) compared with VAD alone in patients with advanced refractory multiple myeloma: an EORTC-HOVON randomized phase III study (06914).

scientific article published in December 2001

Cyclosporin for thrombotic thrombocytopenic purpura after autologous bone marrow transplantation

scientific article

Cytogenetic aberrations in neuropathy associated with IgM monoclonal gammopathy

scientific article published on 01 June 2007

Daratumumab depletes CD38+ immune regulatory cells, promotes T-cell expansion, and skews T-cell repertoire in multiple myeloma

scientific article

Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors.

scientific article

Daratumumab-mediated lysis of primary multiple myeloma cells is enhanced in combination with the human anti-KIR antibody IPH2102 and lenalidomide

scientific article published on 15 December 2014

Determination of the growth fraction in monoclonal gammopathy with the monoclonal antibody Ki-67

scientific article published on 01 August 1988

Determination of the plasma cell labelling index with bromodeoxyuridine in a double fluorescence technique

scientific article published on 01 October 1986

Diagnosis, risk stratification and management of monoclonal gammopathy of undetermined significance and smoldering multiple myeloma

scientific article

Different CD44 splicing patterns define prognostic subgroups in multiple myeloma

scientific article published on 01 October 1996

Diffuse large B-cell lymphoma in immunoprivileged sites: association of vitreoretinal, testicular and central nervous system lymphoma

scientific article published on 02 July 2013

Donor leukocyte infusions are effective in relapsed multiple myeloma after allogeneic bone marrow transplantation ⬇️

scientific article published on November 15, 1997

Donor leukocyte infusions for recurrent hematologic malignancies after allogeneic bone marrow transplantation: impact of infused and residual donor T cells

scientific article published on 01 December 1998

Donor leukocyte infusions inducing remissions repeatedly in a patient with recurrent multiple myeloma after allogeneic bone marrow transplantation

scientific article published on 01 January 1999

Donor lymphocyte infusions for relapsed multiple myeloma after allogeneic stem-cell transplantation: predictive factors for response and long-term outcome

scientific article published on August 2000

Donor versus no-donor comparison of newly diagnosed myeloma patients included in the HOVON-50 multiple myeloma study

scientific article published on 22 March 2012

Dose-finding study of high-dose simvastatin combined with standard chemotherapy in patients with relapsed or refractory myeloma or lymphoma.

scientific article

Drug resistance in multiple myeloma

scientific article published on 01 October 1997

Effect of stem cell transplantation for B-cell malignancies on disease course of associated polyneuropathy ⬇️

scientific article published on March 8, 2012

Effect of thalidomide with melphalan and prednisone on health-related quality of life (HRQoL) in elderly patients with newly diagnosed multiple myeloma: a prospective analysis in a randomized trial ⬇️

scientific article published on April 7, 2011

Effects of daratumumab on natural killer cells and impact on clinical outcomes in relapsed or refractory multiple myeloma

scientific article published on 24 October 2017

Efficacy of host-dendritic cell vaccinations with or without minor histocompatibility antigen loading, combined with donor lymphocyte infusion in multiple myeloma patients

scientific article published on 14 November 2016

Endogenous interleukin 6 production in multiple myeloma patients treated with chimeric monoclonal anti-IL6 antibodies indicates the existence of a positive feed-back loop

scientific article published on September 1996

Eradication of medullary multiple myeloma by CD4+ cytotoxic human T lymphocytes directed at a single minor histocompatibility antigen

scientific article published on 09 November 2010

Erratum to: Practical Considerations for the Use of Daratumumab, a Novel CD38 Monoclonal Antibody, in Myeloma

scientific article published on 20 May 2016

European Myeloma Network recommendations on the evaluation and treatment of newly diagnosed patients with multiple myeloma

scientific article published on February 2014

European Myeloma Network: the 3rd Trialist Forum Consensus Statement from the European experts meeting on multiple myeloma.

scientific article published on 31 August 2010

Experience with outcomes research into the real-world effectiveness of novel therapies in Dutch daily practice from the context of conditional reimbursement

scientific article published on 22 November 2014

Extended follow up of high-dose melphalan and autologous stem cell transplantation after vincristine, doxorubicin, dexamethasone induction in amyloid light chain amyloidosis of the prospective phase II HOVON-41 study by the Dutch-Belgian Co-operativ

scientific article published on 6 February 2015

Extramedullary relapses after allogeneic non-myeloablative stem cell transplantation in multiple myeloma patients do not negatively affect treatment outcome.

scientific article published on 14 January 2008

Extremely high levels of von Willebrand factor antigen and of procoagulant factor VIII found in multiple myeloma patients are associated with activity status but not with thalidomide treatment

scientific article published in March 2003

Feasibility of controlling CD38-CAR T cell activity with a Tet-on inducible CAR design.

scientific article

G3139, a Bcl-2 antisense oligodeoxynucleotide, induces clinical responses in VAD refractory myeloma

scientific article published in June 2004

Gene expression profiling for molecular classification of multiple myeloma in newly diagnosed patients

scientific article published on 23 June 2010

Gene-expression profiling of CD34+ cells from various hematopoietic stem-cell sources reveals functional differences in stem-cell activity

scientific article published on 21 November 2003

Genetic factors underlying the risk of thalidomide-related neuropathy in patients with multiple myeloma.

scientific article published on 18 January 2011

Geranylgeranylated proteins are involved in the regulation of myeloma cell growth.

scientific article published in January 2005

Graft versus myeloma may overcome the unfavorable effect of deletion of chromosome 13 in multiple myeloma

scientific article published on 01 February 2003

Graft-versus-myeloma effect in two cases

scientific article published on 01 March 1996

Growth factors and antiapoptotic signaling pathways in multiple myeloma

scientific article

Hematopoietic stem cell transplantation after reduced intensity conditioning in acute myelogenous leukemia patients older than 40 years

scientific article published on 31 December 2007

High cereblon expression is associated with better survival in patients with newly diagnosed multiple myeloma treated with thalidomide maintenance.

scientific article published on 11 December 2012

High dose simvastatin does not reverse resistance to vincristine, adriamycin, and dexamethasone (VAD) in myeloma

scientific article published in December 2007

High-Parameter Mass Cytometry Evaluation of Relapsed/Refractory Multiple Myeloma Patients Treated with Daratumumab Demonstrates Immune Modulation as a Novel Mechanism of Action

scientific article published on 11 December 2018

High-dose melphalan versus melphalan plus dexamethasone for AL amyloidosis

scientific article published on 01 January 2008

High-risk multiple myeloma treated with high-dose melphalan ⬇️

scientific article published on 01 January 1992

How I treat plasma cell leukemia

scientific article

Human Regulatory T Cells Do Not Suppress the Antitumor Immunity in the Bone Marrow: A Role for Bone Marrow Stromal Cells in Neutralizing Regulatory T Cells ⬇️

scientific article published on February 4, 2013

Hypofibrinolysis during induction treatment of multiple myeloma may increase the risk of venous thrombosis

scientific article published on 01 December 2005

IMWG consensus on maintenance therapy in multiple myeloma

scientific article published on 23 January 2012

Idarubicin overcomes P-glycoprotein-related multidrug resistance: comparison with doxorubicin and daunorubicin in human multiple myeloma cell lines

scientific article published on June 1999

Identification of minor histocompatibility antigens based on the 1000 Genomes Project

scientific article

Illegitimate WNT signaling promotes proliferation of multiple myeloma cells

scientific article

Immune function during ageing in man: relation between serological abnormalities and cellular immune status

scientific article published on 01 June 1983

Immune-modulatory effects of bortezomib in GVHD

scientific article published on 01 May 2007

Immunoglobulin gene analysis in polyneuropathy associated with IgM monoclonal gammopathy

scientific article published on 06 March 2006

Immunotherapy in myeloma: how far have we come?

scientific article published on 18 January 2019

Impact of Fc gamma receptor polymorphisms on efficacy and safety of daratumumab in relapsed/refractory multiple myeloma.

scientific article published on 7 February 2018

Impact of ocular graft‐versus‐host disease on visual quality of life in patients after allogeneic stem cell transplantation: questionnaire study ⬇️

scientific article published on April 22, 2013

Increased plasmin-α2-antiplasmin levels indicate activation of the fibrinolytic system in systemic amyloidoses

scientific article published on 20 February 2007

Induction therapy with vincristine, adriamycin, dexamethasone (VAD) and intermediate-dose melphalan (IDM) followed by autologous or allogeneic stem cell transplantation in newly diagnosed multiple myeloma

scientific article published on 01 February 1999

Influence of Disease and Patient Characteristics on Daratumumab Exposure and Clinical Outcomes in Relapsed or Refractory Multiple Myeloma

scientific article

Influence of genetic polymorphisms in CYP3A4, CYP3A5, GSTP1, GSTM1, GSTT1 and MDR1 genes on survival and therapy-related toxicity in multiple myeloma

scientific article published on 01 February 2007

Inhibition of protein geranylgeranylation induces apoptosis in myeloma plasma cells by reducing Mcl-1 protein levels

scientific article

Inhibition of the mevalonate pathway potentiates the effects of lenalidomide in myeloma

scientific article

Intensive treatment for multiple myeloma: where do we stand?

scientific article

Interleukin-6, a new target for therapy in multiple myeloma?

scientific article

Intermediate-dose melphalan (IDM) combined with G-CSF (filgrastim) is an effective and safe induction therapy for autologous stem cell transplantation in multiple myeloma

scientific article published on 01 January 1996

Intermediate-dose melphalan compared with myeloablative treatment in multiple myeloma: long-term follow-up of the Dutch Cooperative Group HOVON 24 trial

scientific article published on 01 July 2007

Intermittent cyclophosphamide and prednisone treatment of polyneuropathy associated with monoclonal gammopathy of undetermined significance

scientific article

Intermittent cyclophosphamide with prednisone versus placebo for polyneuropathy with IgM monoclonal gammopathy

scientific article published in July 2007

International Myeloma Working Group consensus statement regarding the current status of allogeneic stem-cell transplantation for multiple myeloma

scientific article published on 09 August 2010

International myeloma working group consensus statement and guidelines regarding the current role of imaging techniques in the diagnosis and monitoring of multiple Myeloma

scientific article (publication date: September 2009)

J chain disease: an aggressive evolution of multiple myeloma

scientific article published on 01 April 1990

Joint HOVON-50/GMMG-HD3 randomized trial on the effect of thalidomide as part of a high-dose therapy regimen and as maintenance treatment for newly diagnosed myeloma patients

scientific article published on 4 July 2003

Laryngeal amyloidosis: localized versus systemic disease and update on diagnosis and therapy.

scientific article

Lenalidomide (Revlimid) combined with continuous oral cyclophosphamide (endoxan) and prednisone (REP) is effective in lenalidomide/dexamethasone-refractory myeloma

scientific article published in January 2010

Lenalidomide alone or in combination with dexamethasone is highly effective in patients with relapsed multiple myeloma following allogeneic stem cell transplantation and increases the frequency of CD4+Foxp3+ T cells.

scientific article

Lenalidomide combined with low-dose cyclophosphamide and prednisone modulates Ikaros and Aiolos in lymphocytes, resulting in immunostimulatory effects in lenalidomide-refractory multiple myeloma patients

Lenalidomide for the treatment of relapsed and refractory multiple myeloma.

scientific article

Lenalidomide maintenance after nonmyeloablative allogeneic stem cell transplantation in multiple myeloma is not feasible: results of the HOVON 76 Trial

scientific article published on 20 June 2011

Lenalidomide versus bortezomib maintenance after frontline autologous stem cell transplantation for multiple myeloma

scientific article published on 07 January 2021

Leptomeningeal metastases from primary plasma cell leukemia

scientific article published on 01 October 2013

Localized graft-versus-host disease of the skin provoked by radiotherapy

scientific article published on 24 April 2010

Long‐term bone marrow cultured stromal cells regulate myeloma tumour growth in vitro: studies with primary tumour cells and LTBMC‐dependent cell lines ⬇️

scientific article published on 01 January 1998

Low incidence of infectious complications after nonmyeloablative compared with myeloablative allogeneic stem cell transplantation

scientific article

Lung-resistance-related protein expression is a negative predictive factor for response to conventional low but not to intensified dose alkylating chemotherapy in multiple myeloma ⬇️

scientific article published on 01 February 1998

Lymphocyte function-associated antigen-1 expression on plasma cells correlates with tumor growth in multiple myeloma

scientific article published on 01 April 1992

MDR-1 expression and response to vincristine, doxorubicin, and dexamethasone chemotherapy in multiple myeloma refractory to alkylating agents

scientific article published in January 1994

Malignant transformation in polyneuropathy associated with monoclonal gammopathy

scientific article

Malignant transformation of monoclonal gammopathy of undetermined significance: cumulative incidence and prognostic factors

scientific article

Mechanisms of peripheral neuropathy associated with bortezomib and vincristine in patients with newly diagnosed multiple myeloma: a prospective analysis of data from the HOVON-65/GMMG-HD4 trial

scientific article

Micro-RNA-15a and micro-RNA-16 expression and chromosome 13 deletions in multiple myeloma

scientific article published on 23 December 2009

MicroRNA signatures characterize multiple myeloma patients

scientific article published on 24 June 2011

Minor histocompatibility Ags: identification strategies, clinical results and translational perspectives

scientific article

Misfolded proteins activate factor XII in humans, leading to kallikrein formation without initiating coagulation

scientific article

Modern treatment methods for multiple myeloma: guidelines from the Dutch Haemato-Oncology Association (HOVON)

scientific article published in April 2005

Modulation of chronic excessive interleukin-6 production in multiple mycloma does not affect thyroid hormone concentrations ⬇️

scientific article published on 01 November 1997

Modulation of multidrug-resistant multiple myeloma by cyclosporin. The Leukaemia Group of the EORTC and the HOVON

scientific article published on August 1, 1992

Molecular remission after myeloablative allogeneic stem cell transplantation predicts a better relapse-free survival in patients with multiple myeloma

scientific article

Monoclonal antibodies targeting CD38 in hematological malignancies and beyond

scientific article

Monoclonal antibody-based therapy as a new treatment strategy in multiple myeloma

scientific article published on 19 August 2011

Monocytes and Granulocytes Reduce CD38 Expression Levels on Myeloma Cells in Patients Treated with Daratumumab

scientific article

Multidrug-resistant acute leukemia cells are responsive to prolonged exposure of daunorubicin: Implications for liposome-encapsulated daunorubicin ⬇️

scientific article published on March 1, 1998

Multiple myeloma; treatment in the year 1998

scientific article published on July 11, 1998

Natural history of relapsed myeloma, refractory to immunomodulatory drugs and proteasome inhibitors: a multicenter IMWG study

scientific article published on 12 May 2017

Neurologic and hematologic response to fludarabine treatment in IgM MGUS polyneuropathy

scientific article published on 01 December 2006

New developments in the management and treatment of newly diagnosed and relapsed/refractory multiple myeloma patients

scientific article

New developments in the treatment of patients with multiple myeloma

scientific article published on January 2010

New treatment strategies for multiple myeloma by targeting BCL-2 and the mevalonate pathway

scientific article

Novel type of proliferating lymphoplasmacytoid cell with a characteristic spotted immunofluorescence pattern

scientific article

Ocular graft-versus-host disease after allogeneic stem cell transplantation

scientific article published on 01 July 2010

Outcome of allogeneic transplantation in newly diagnosed and relapsed/refractory multiple myeloma: long-term follow-up in a single institution

scientific article

Overall and event-free survival are not improved by the use of myeloablative therapy following intensified chemotherapy in previously untreated patients with multiple myeloma: a prospective randomized phase 3 study

scientific article published on 27 November 2002

Partially T-cell-depleted allogeneic stem-cell transplantation for first-line treatment of multiple myeloma: a prospective evaluation of patients treated in the phase III study HOVON 24 MM

scientific article published on 01 May 2003

Personalized therapy in multiple myeloma according to patient age and vulnerability: a report of the European Myeloma Network (EMN).

scientific article published on 12 August 2011

Pharmacokinetics of Daratumumab Following Intravenous Infusion in Relapsed or Refractory Multiple Myeloma After Prior Proteasome Inhibitor and Immunomodulatory Drug Treatment

scientific article published on 29 November 2016

Phase 1/2 study of daratumumab, lenalidomide, and dexamethasone for relapsed multiple myeloma.

scientific article

Phase 1/2 study of lenalidomide combined with low-dose cyclophosphamide and prednisone in lenalidomide-refractory multiple myeloma

scientific article

Phase 2 study of carfilzomib, thalidomide, and dexamethasone as induction/consolidation therapy for newly diagnosed multiple myeloma

scientific article

Phase 2 study of carfilzomib, thalidomide, and low-dose dexamethasone as induction and consolidation in newly diagnosed, transplant eligible patients with multiple myeloma, the carthadex trial

scientific article published on 04 April 2019

Phase I/II trial of weekly bortezomib with lenalidomide and dexamethasone in first relapse or primary refractory myeloma

scientific article published on 11 December 2015

Phase III study of the value of thalidomide added to melphalan plus prednisone in elderly patients with newly diagnosed multiple myeloma: the HOVON 49 Study

scientific article published in June 2010

Polyneuropathy associated with monoclonal gammopathy of undetermined significance. A prospective study of the prognostic value of clinical and laboratory abnormalities

scientific article published on 01 December 1994

Potential prognostic implications of whole-body bone marrow MRI in diffuse large B-cell lymphoma patients with a negative blind bone marrow biopsy

scientific article

Practical Considerations for the Use of Daratumumab, a Novel CD38 Monoclonal Antibody, in Myeloma

scientific article published on 25 April 2016

Pre-clinical evaluation of CD38 chimeric antigen receptor engineered T cells for the treatment of multiple myeloma.

scientific article published on 8 February 2016

Pre-diagnostic blood immune markers, incidence and progression of B-cell lymphoma and multiple myeloma: Univariate and functionally informed multivariate analyses

scientific article published on 18 April 2018

Preclinical Evidence for the Therapeutic Potential of CD38-Targeted Immuno-Chemotherapy in Multiple Myeloma Patients Refractory to Lenalidomide and Bortezomib

scientific article

Preclinical evaluation of CD38 chimeric antigen receptor engineered T cells for the treatment of multiple myeloma

scientific article published on 4 November 2015

Preclinical evidence for an effective therapeutic activity of FL118, a novel survivin inhibitor, in patients with relapsed/refractory multiple myeloma

scientific article published on 31 January 2020

Prediction of high- and low-risk multiple myeloma based on gene expression and the International Staging System ⬇️

scientific article

Prevention of venous thromboembolism with low molecular-weight heparin in patients with multiple myeloma treated with thalidomide and chemotherapy

scientific article published in December 2004

Primary tumor cells of myeloma patients induce interleukin-6 secretion in long-term bone marrow cultures

scientific article published on October 1994

Prognostic factors and outcome in relapsed multiple myeloma after nonmyeloablative allo-SCT: a single center experience

scientific article published on 19 April 2010

Prognostic factors for donor lymphocyte infusions following non-myeloablative allogeneic stem cell transplantation in multiple myeloma.

scientific article published in June 2006

Prospective evaluation of coagulopathy in multiple myeloma patients before, during and after various chemotherapeutic regimens

scientific article

Protein geranylgeranylation is critical for the regulation of survival and proliferation of lymphoma tumor cells

scientific article published on November 2003

Pulsed high-dose dexamethasone is not effective in patients with multifocal motor neuropathy

scientific article published on 01 April 1997

Pulsed high-dose dexamethasone treatment of polyneuropathy associated with monoclonal gammopathy ⬇️

scientific article published on 01 July 1997

Putative myeloma precursor cells expressing 2,6 sialic acid-modified antigens actually belong to the erythroid lineage ⬇️

scientific article published on 01 February 1998

Rapid identification of clinical relevant minor histocompatibility antigens via genome-wide zygosity-genotype correlation analysis

scientific article published on 24 November 2009

Rebuilding human leukocyte antigen class II-restricted minor histocompatibility antigen specificity in recall antigen-specific T cells by adoptive T cell receptor transfer: implications for adoptive immunotherapy.

scientific article

Reduced relapse rate in upfront tandem autologous/reduced-intensity allogeneic transplantation in multiple myeloma only results in borderline non-significant prolongation of progression-free but not overall survival

scientific article published on 4 September 2015

Remarkable activity of novel agents bortezomib and thalidomide in patients not responding to donor lymphocyte infusions following nonmyeloablative allogeneic stem cell transplantation in multiple myeloma

scientific article published on 01 April 2006

Revised International Staging System for Multiple Myeloma: A Report From International Myeloma Working Group

scientific article published on 3 August 2015

Risk factors for hematological malignancy in polyneuropathy associated with monoclonal gammopathy

scientific article published on 01 October 2001

Rituximab treatment before reduced-intensity conditioning transplantation associates with a decreased incidence of extensive chronic GVHD.

scientific article published on 16 April 2009

Safety of thalidomide in newly diagnosed elderly myeloma patients: a meta-analysis of data from individual patients in six randomized trials

scientific article

Salvage therapy with ProMACE-MOPP followed by intensive chemoradiotherapy and autologous bone marrow transplantation for patients with non-Hodgkin's lymphoma who failed to respond to first-line CHOP ⬇️

scientific article published on December 1, 1992

Secondary monoclonal gammopathy of undetermined significance after allogeneic stem cell transplantation in multiple myeloma

scientific article

Selective in vitro expansion and efficient retroviral transduction of human CD34+ CD38- haematopoietic stem cells

scientific article

Sepantronium bromide (YM155) improves daratumumab-mediated cellular lysis of multiple myeloma cells by abrogation of bone marrow stromal cell-induced resistance.

scientific article published on 5 May 2016

Single-centre experience with nonmyeloablative allogeneic stem cell transplantation in patients with multiple myeloma: prolonged remissions induced

scientific article published on 01 May 2007

Sporadic late-onset nemaline myopathy effectively treated by melphalan and stem cell transplant

scientific article published on 18 June 2008

Sporadic late-onset nemaline myopathy with MGUS: long-term follow-up after melphalan and SCT.

scientific article published on 5 November 2014

Susceptibility of malignant plasma cells to HA-1(H) specific lysis suggests a role for the minor histocompatibility antigen HA-1 in the graft-versus-myeloma effect

scientific article published on 01 September 2004

T Cells Specific for an Unconventional Natural Antigen Fail to Recognize Leukemic Cells

scientific article published on 19 March 2019

Targeting CD38 with Daratumumab Monotherapy in Multiple Myeloma

scientific article

Thalidomide before and after autologous stem cell transplantation in recently diagnosed multiple myeloma (HOVON-50): long-term results from the phase 3, randomised controlled trial

scientific article published on 01 October 2018

Thalidomide in induction treatment increases the very good partial response rate before and after high-dose therapy in previously untreated multiple myeloma

scientific article published in January 2008

Thalidomide in newly diagnosed multiple myeloma: influence of thalidomide treatment on peripheral blood stem cell collection yield

scientific article published on 22 March 2007

Thalidomide in the treatment of refractory multiple myeloma: a Dutch study of 72 patients: an antitumor effect in 45%

scientific article published in August 2002

The SCID mouse as a model for multiple myeloma

scientific article published on 01 February 1995

The cholesterol lowering drug lovastatin induces cell death in myeloma plasma cells

scientific article published in July 2002

The clinical relevance and management of monoclonal gammopathy of undetermined significance and related disorders: recommendations from the European Myeloma Network

scientific article

The hepatocyte growth factor/Met pathway controls proliferation and apoptosis in multiple myeloma.

scientific article published in April 2003

The immunological phenotype of rituximab-sensitive chronic graft-versus-host disease: a phase II study

scientific article

The impact of circulating suppressor cells in multiple myeloma patients on clinical outcome of DLIs.

scientific article published on 23 March 2015

The occurrence of graft-versus-host disease is the major predictive factor for response to donor lymphocyte infusions in multiple myeloma

scientific article published on 19 February 2004

The therapeutic human CD38 antibody daratumumab improves the anti-myeloma effect of newly emerging multi-drug therapies

scientific article published on 28 October 2011

Therapeutic options in systemic AL amyloidosis

scientific article published in April 2004

Three families with polyneuropathy associated with monoclonal gammopathy

scientific article published on 01 May 2000

Toward targeting B cell cancers with CD4+ CTLs: identification of a CD19-encoded minor histocompatibility antigen using a novel genome-wide analysis

scientific article published on 10 November 2008

Towards effective and safe immunotherapy after allogeneic stem cell transplantation: identification of hematopoietic-specific minor histocompatibility antigen UTA2-1.

scientific article published on October 2012

Towards effective immunotherapy of myeloma: enhanced elimination of myeloma cells by combination of lenalidomide with the human CD38 monoclonal antibody daratumumab

scientific article published on 25 November 2010

Translocation of the IgH locus is nearly ubiquitous in multiple myeloma as detected by immuno-FISH

scientific article published on 01 February 2003

Treatment of relapsed and refractory multiple myeloma in the era of novel agents

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