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List of works by Ichiro Hirata

779 TC of CCK-1 intron 1 is associated with postprandial syndrome (PDS) in Japanese male subjects.

scientific article published in July 2009

A Genetic Variant of the CD14 C-159T in Patients with Functional Dyspepsia (FD) in Japanese Subjects

scientific article

A case of plummer-vinson syndrome showing rapid improvement of Dysphagia and esophageal web after two weeks of iron therapy

scientific article

A genetic variant of the p22PHOX component of NADPH oxidase C242T is associated with reduced risk of functional dyspepsia in Helicobacter pylori-infected Japanese individuals

scientific article published in December 2009

A polymorphism in the 3'-utr of cyclooxygenase-2 and the risk of gastric cancer

scientific article published on 01 July 2008

A polymorphism of microRNA 27a genome region is associated with the development of gastric mucosal atrophy in Japanese male subjects

scientific article published on 16 March 2007

Absence of Common Polymorphisms of Toll Like Receptor 4 (TLR4): Asp299Gly, Thr399Ile in Patients with Gastroduodenal Diseases in Japan

scientific article published on January 2007

Analysis of Beta-Tubulin Gene Exon 4 Mutations in Advanced Stage III or IV Gastric Cancer

scientific article published in May 2007

Association Between Common Genetic Variants in Pre‐microRNAs and Gastric Cancer Risk in Japanese Population ⬇️

scientific article published on 01 December 2010

Association between IL-17A, -17F and MIF polymorphisms predispose to CpG island hyper-methylation in gastric cancer

scientific article published on 01 March 2010

Association between common genetic variants in pre-microRNAs and prognosis of advanced gastric cancer treated with chemotherapy.

scientific article published in September 2014

Association between common genetic variants in pre-microRNAs and the clinicopathological characteristics and survival of gastric cancer patients ⬇️

scientific article published on September 29, 2010

Association between cyclin D1 (CCND1) polymorphism and gastric cancer risk in Japanese population

scientific article published on 01 July 2009

Association between cyclin D1 polymorphism with CpG island promoter methylation status of tumor suppressor genes in gastric cancer.

scientific article published on 16 April 2010

Association between genetic polymorphisms in the cyclooxygenase-1 gene promoter and peptic ulcers in Japan

scientific article published on 01 September 2007

Association between genetic polymorphisms related to DNA repair or xenobiotic pathways and gastric premalignant conditions

scientific article published on April 1, 2011

Association between individual response to food taste and gastroesophageal symptoms

scientific article published on 01 June 2015

Association between interleukin-1β and tumor necrosis factor-α polymorphisms and symptoms of dyspepsia

scientific article published on 08 January 2015

Association between polymorphisms in the XRCC1 and GST genes, and CpG island methylation status in colonic mucosa in ulcerative colitis

scientific article published on 14 January 2011

Association between promoter polymorphisms of nuclear factor-erythroid 2-related factor 2 gene and peptic ulcer diseases.

scientific article

Association of endoscopic appearances with dyspeptic symptoms

scientific article

Association of polymorphism of the p22PHOX component of NADPH oxidase in gastroduodenal diseases in Japan

scientific article published in January 2009

Association study of common genetic variants in pre-microRNAs in patients with ulcerative colitis

scientific article published on 17 September 2010

CD14 promoter-159 polymorphism is associated with reduced risk of intestinal-type gastric cancer in a Japanese population

scientific article published on 27 March 2009

COMT gene Val158Met polymorphism influences the severity of intestinal metaplasia in H. pylori infected older subjects.

scientific article

COMT gene val158met polymorphism in patients with dyspeptic symptoms.

scientific article published in May 2008

Change in DNA methylation patterns of SLC6A4 gene in the gastric mucosa in functional dyspepsia

scientific article

Changes in gastric mucosal patterns seen by magnifying NBI during H. pylori eradication ⬇️

scientific article published on October 22, 2010

Chronic aspirin use suppresses CDH1 methylation in human gastric mucosa

scientific article published on 29 January 2009

Chronic nonsteroidal anti-inflammatory drug (NSAID) use suppresses multiple CpG islands hyper methylation (CIHM) of tumor suppressor genes in the human gastric mucosa.

scientific article published on 4 May 2009

Comprehensive DNA Methylation Profiling of Inflammatory Mucosa in Ulcerative Colitis

scientific article published on 7 December 2016

Correlation between magnifying narrow band imaging and histopathology in gastric protruding/or polypoid lesions: a pilot feasibility trial ⬇️

scientific article published on February 22, 2012

CpG island promoter methylation (CIHM) status of tumor suppressor genes correlates with morphological appearances of gastric cancer

scientific article published on 01 January 2010

DNA methylation status of epithelial-mesenchymal transition (EMT)--related genes is associated with severe clinical phenotypes in ulcerative colitis (UC).

scientific article

Diagnostic efficacy of autofluorescence and reflectance imaging endoscopy for lateral extension of early gastric cancers

scientific article published on 01 September 2009

Downregulation of anti-oncomirs miR-143/145 cluster occurs before APC gene aberration in the development of colorectal tumors.

scientific article published on 9 February 2013

Effect of IL-1β and TNF-α polymorphisms on the prognosis and survival of gastric cancer patients

scientific article published on 19 January 2011

Effect of MDR1 gene promoter methylation in patients with ulcerative colitis

scientific article

Effect of RANTES gene promoter genotypes in patients with ulcerative colitis

scientific article

Effect of RANTES promoter genotype on the severity of intestinal metaplasia in Helicobacter pylori-infected Japanese subjects

scientific article published on 29 October 2008

Effect of cyclin D1 (CCND1) polymorphism on gastric premalignant condition

scientific article published in January 2008

Effect of genetic polymorphisms related to DNA repair and the xenobiotic pathway on the prognosis and survival of gastric cancer patients

scientific article published on 01 February 2011

Effect of polymorphisms in the 3' untranslated region (3'-UTR) of vascular endothelial growth factor gene on gastric cancer and peptic ulcer diseases in Japan

scientific article published in November 2009

Effect of polymorphisms in the 3'-untranslated region (3'-UTR) of VEGF gene on gastric pre-malignant condition.

scientific article published in February 2009

Effect of polymorphisms of IL-17A, -17F and MIF genes on CpG island hyper-methylation (CIHM) in the human gastric mucosa.

scientific article

Effect of polymorphisms of IL‐1β and TNF‐α genes on CpG island hyper methylation (CIHM) in the nonneoplastic gastric mucosa ⬇️

scientific article published on March 11, 2011

Effect of promoter methylation of multidrug resistance 1 (MDR1) gene in gastric carcinogenesis

scientific article published in January 2009

Examination of serum pepsinogen in functional dyspepsia

scientific article published on November 1, 2012

Examination of whole blood DNA methylation as a potential risk marker for gastric cancer

scientific article

Functional polymorphisms in the promoter region of macrophage migration inhibitory factor and chronic gastritis

scientific article published on 01 October 2007

Functional promoter polymorphisms of the macrophage migration inhibitory factor gene in gastric carcinogenesis

scientific article published in January 2008

Fusobacterium detected in colonic biopsy and clinicopathological features of ulcerative colitis in Japan

scientific article published on 8 August 2014

Gastric mucosal pattern by using magnifying narrow-band imaging endoscopy clearly distinguishes histological and serological severity of chronic gastritis

scientific article published on 21 April 2009

Gastric pyogenic granuloma detected due to abdominal symptoms and treated with endoscopic resection

scientific article published on January 2013

Gastrointestinal Stromal Tumor of the Stomach with Narrow Stalk-Like Based, Uneven Protruding Appearance Presenting with Severe Acute Anemia despite Small Size

scientific article published on 20 March 2010

Genetic Polymorphisms of Molecules Associated with Innate Immune Responses, TRL2 and MBL2 Genes in Japanese Subjects with Functional Dyspepsia

scientific article

Genetic polymorphism of interleukin-17A and -17F genes in gastric carcinogenesis

scientific article published on 3 May 2009

Genetic polymorphisms of CD14 and Toll-like receptor-2 (TLR2) in patients with ulcerative colitis

scientific article

Genetic polymorphisms of cyclooxygenase-1 (COX-1) are associated with functional dyspepsia in Japanese women

scientific article published in July 2008

Genetic polymorphisms of molecules associated with inflammation and immune response in Japanese subjects with functional dyspepsia

scientific article published on 01 November 2007

Genetic variant of the p22PHOX component of NADPH oxidase C242T and the incidence of gastric cancer in Japan.

scientific article published in November 2008

Heat-shock protein 70-2 BB genotype is associated with reduced risks of the steroid-dependent and refractory phenotypes of ulcerative colitis

scientific article published on 21 May 2014

Homozygous 825T allele of the GNB3 protein influences the susceptibility of Japanese to dyspepsia

scientific article published on 24 August 2007

Homozygous TRPV1 315C influences the susceptibility to functional dyspepsia

scientific article published on 01 January 2010

Host genetic factors, related to inflammatory response, influence the CpG island methylation status in colonic mucosa in ulcerative colitis.

scientific article

Impact of catechol-O-methyltransferase (COMT) gene polymorphism on promoter methylation status in gastric mucosa.

scientific article

Increased number of CpG island hypermethylation in tumor suppressor genes of non-neoplastic gastric mucosa correlates with higher risk of gastric cancer

scientific article published on 11 February 2010

Increased number of methylated CpG islands correlates with Helicobacter pylori infection, histological and serological severity of chronic gastritis

scientific article published on 01 June 2009

Influence of MDR1 polymorphism on H. pylori-related chronic gastritis

scientific article published on 13 May 2010

Influence of peroxisome proliferator-activated receptor (PPAR)gamma Plo12Ala polymorphism as a shared risk marker for both gastric cancer and impaired fasting glucose (IFG) in Japanese

scientific article published in September 2007

Light blue crest and ridge/villous patterns in the uninvolved gastric antrum by magnifying NBI endoscopy correlate with serum pepsinogen and gastric cancer occurrence

scientific article published in March 2014

Low-dose aspirin induced intestinal damage -including the influence of low-dose aspirin to existing lesions-

scientific article published on December 1, 2010

MTHFR 677T carrier influences the methylation status of H. pylori-infected gastric mucosa in older subjects

scientific article

Management of small-bowel polyps at double-balloon enteroscopy

scientific article

Mannan-binding lectin (MBL) polymorphism and gastric cancer risk in Japanese population

scientific article published on 27 March 2008

Mannan-binding lectin B allele is associated with a risk of developing more severe gastric mucosal atrophy in Helicobacter pylori-infected Japanese patients

scientific article

Multi-drug resistance 1 polymorphism is associated with reduced risk of gastric cancer in the Japanese population

scientific article published on 29 June 2007

No association between a genetic variant of the p22PHOX component of NADPH oxidase C242T and ulcerative colitis

scientific article published in September 2008

Nrf2 gene promoter polymorphism and gastric carcinogenesis

scientific article published on 01 March 2008

Nrf2 gene promoter polymorphism is associated with ulcerative colitis in a Japanese population

scientific article

Obscure gastrointestinal bleeding: diagnosis and treatment

scientific article published on 03 February 2015

Polymorphism of the salt sensitivity gene angiotensinogen and gastric cancer risk ⬇️

scientific article published on May 16, 2011

Polymorphisms of DNA Repair and Xenobiotic Genes Predispose to CpG Island Methylation in Non‐Neoplastic Gastric Mucosa ⬇️

scientific article published on April 1, 2011

Potential link between Fusobacterium enrichment and DNA methylation accumulation in the inflammatory colonic mucosa in ulcerative colitis

scientific article published on 27 June 2017

Presence of minimal change esophagitis closely correlates with pathological conditions in the stomach

scientific article published on 17 November 2011

Promoter hypomethylation of protease-activated receptor 2 associated with carcinogenesis in the stomach.

scientific article published on 22 May 2007

Promoter methylation of protease-activated receptor (PAR2) is associated with severe clinical phenotypes of ulcerative colitis (UC).

scientific article published on 30 January 2009

Promoter methylation status of multidrug resistance 1 (MDR1) gene in noncancerous gastric mucosa correlates with Helicobacter Pylori infection and gastric cancer occurrence

scientific article published on 01 August 2010

Promoter polymorphism of cyclooxygenase-1 (COX1) is not associated with ulcerative colitis in the Japanese population

scientific article published on 01 May 2008

Protective role of genetic polymorphism of heat shock protein 70-2 for gastric cancer risk

scientific article published on 14 May 2008

RANTES promoter genotype and gastric cancer risk in a Japanese population

scientific article published on 01 October 2009

Relationship between expression of onco-related miRNAs and the endoscopic appearance of colorectal tumors

scientific article

Risk prediction of gastric cancer by analysis of aberrant DNA methylation in non-neoplastic gastric epithelium

scientific article published on 16 April 2007

Role of heat-shock protein (HSP) 70-2 genotype in peptic ulcer in Japanese population

scientific article published on March 1, 2012

Selenoprotein S (SEPS1) gene -105G>A promoter polymorphism influences the susceptibility to gastric cancer in the Japanese population

scientific article published on 13 January 2009

Serotonin-2A receptor gene T102C polymorphism in patients with dyspeptic symptoms

scientific article

Synergistic effect of IL-1β and TNF-α polymorphisms on the H. pylori-related gastric pre-malignant condition

scientific article published on November 1, 2012

Telomere length in non-neoplastic colonic mucosa in ulcerative colitis (UC) and its relationship to the severe clinical phenotypes.

scientific article

Telomere length in non-neoplastic gastric mucosa and its relationship to H. pylori infection, degree of gastritis, and NSAID use.

scientific article published on 7 January 2015

The BB genotype of heat-shock protein (HSP) 70-2 gene is associated with gastric pre-malignant condition in H. pylori-infected older patients.

scientific article

The G-protein β3 polymorphism is associated with diffuse type gastric cancer in Japanese

scientific article published on January 1, 2010

The Role of RANTES Promoter Polymorphism in Functional Dyspepsia

scientific article published on 28 August 2009

The effect of consuming small volumes of beer on gastric motility and the involvement of gene polymorphisms

scientific article published in January 2016

The influence of polymorphisms of interleukin-17A and interleukin-17F genes on the susceptibility to ulcerative colitis

scientific article published on 09 September 2007

The influence of promoter polymorphism of nuclear factor-erythroid 2-related factor 2 gene on the aberrant DNA methylation in gastric epithelium

scientific article published on 01 January 2008

The mucosal pattern in the non-neoplastic gastric mucosa by using magnifying narrow-band imaging endoscopy significantly correlates with gastric cancer risk

scientific article published on 01 February 2010

The relationship between Helicobacter pylori infection and promoter polymorphism of the Nrf2 gene in chronic gastritis.

scientific article published in January 2007

The usefulness of magnifying endoscopy with narrow-band imaging to distinguish carcinoma in flat elevated lesions in the stomach diagnosed as adenoma by using biopsy samples

scientific article published in May 2010

Toll-like receptor 2 (TLR) -196 to 174del polymorphism in gastro-duodenal diseases in Japanese population

scientific article published on 13 October 2007

Toll-like receptor 2 -196 to 174del polymorphism influences the susceptibility of Japanese people to gastric cancer

scientific article published on 16 August 2007

Usefulness of magnifying narrow-band imaging endoscopy in the Helicobacter pylori-related chronic gastritis

scientific article published on 21 January 2011

Usefulness of transnasal endoscopy where endoscopic submucosal dissection is difficult ⬇️

scientific article published on June 14, 2011

WITHDRAWN: Peroxisome proliferator-activated receptor gamma Plo12Ala polymorphism influences the susceptibility of a Japanese population to gastric cancer

retracted scientific article published on 18 June 2007

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