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List of works by Edward W. Kraegen

AICAR administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fat-fed rats

scientific article published in October 2002

AMP-activated protein kinase activation by AICAR increases both muscle fatty acid and glucose uptake in white muscle of insulin-resistant rats in vivo

scientific article

AMP-activated protein kinase and muscle insulin resistance

scientific article published on January 2009

APPL1 potentiates insulin-mediated inhibition of hepatic glucose production and alleviates diabetes via Akt activation in mice.

scientific article published in May 2009

Activation of AMPK by bitter melon triterpenoids involves CaMKKβ

scientific article

Acute bidirectional manipulation of muscle glucose uptake by in vivo electrotransfer of constructs targeting glucose transporter genes

scientific article published on September 2005

Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity

scientific article

Adipose triglyceride lipase regulation of skeletal muscle lipid metabolism and insulin responsiveness

scientific article

Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: a mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action

scientific article

Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states

scientific article published on August 2006

Differing endoplasmic reticulum stress response to excess lipogenesis versus lipid oversupply in relation to hepatic steatosis and insulin resistance.

scientific article

Downregulation of AMPK accompanies leucine- and glucose-induced increases in protein synthesis and insulin resistance in rat skeletal muscle

scientific article published on 3 August 2010

Enhancement of muscle mitochondrial oxidative capacity and alterations in insulin action are lipid species dependent: potent tissue-specific effects of medium-chain fatty acids

scientific article published on 31 August 2009

Fat partitioning and insulin sensitivity: robbing Peter to pay Paul?

scientific article published on January 2009

Fatty acid metabolism, energy expenditure and insulin resistance in muscle

scientific article published on 15 January 2014

Free fatty acids and skeletal muscle insulin resistance

scientific article published on June 2008

Functional studies of Akt isoform specificity in skeletal muscle in vivo; maintained insulin sensitivity despite reduced insulin receptor substrate-1 expression

scientific article published on 04 October 2006

Glucose infusion causes insulin resistance in skeletal muscle of rats without changes in Akt and AS160 phosphorylation

scientific article published on 04 September 2007

Increased efficiency of fatty acid uptake contributes to lipid accumulation in skeletal muscle of high fat-fed insulin-resistant rats

scientific article

Increased malonyl-CoA and diacylglycerol content and reduced AMPK activity accompany insulin resistance induced by glucose infusion in muscle and liver of rats

scientific article published on 18 October 2005

Insulin resistance due to nutrient excess: is it a consequence of AMPK downregulation?

scientific article published on October 2011

Insulin resistance is a cellular antioxidant defense mechanism

scientific article

Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation

scientific article published on 14 April 2009

Lipocalin-2 is an inflammatory marker closely associated with obesity, insulin resistance, and hyperglycemia in humans.

scientific article

Local activation of the IkappaK-NF-kappaB pathway in muscle does not cause insulin resistance.

scientific article published on 20 November 2007

Major urinary protein-1 increases energy expenditure and improves glucose intolerance through enhancing mitochondrial function in skeletal muscle of diabetic mice

scientific article

Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle

scientific article

Metformin prevents the development of acute lipid-induced insulin resistance in the rat through altered hepatic signaling mechanisms

scientific article published in December 2004

Minimal impact of age and housing temperature on the metabolic phenotype of Acc2-/- mice

scientific article published on 14 December 2015

Minireview: malonyl CoA, AMP-activated protein kinase, and adiposity

scientific article published on 18 September 2003

Muscle insulin resistance: a case of fat overconsumption, not mitochondrial dysfunction

scholarly article

Nutrient Excess and AMPK Downregulation in Incubated Skeletal Muscle and Muscle of Glucose Infused Rats

scientific article published on 21 May 2015

Oleanolic acid reduces hyperglycemia beyond treatment period with Akt/FoxO1-induced suppression of hepatic gluconeogenesis in type-2 diabetic mice.

scientific article

Oral administration of glucose promotes intracellular partitioning of fatty acid toward storage in white but not in red muscle

scientific article published in September 2006

Overexpression of SIRT1 in rat skeletal muscle does not alter glucose induced insulin resistance

scientific article

Overexpression of acyl-CoA synthetase-1 increases lipid deposition in hepatic (HepG2) cells and rodent liver in vivo

scientific article published on 16 May 2006

Overexpression of carnitine palmitoyltransferase I in skeletal muscle in vivo increases fatty acid oxidation and reduces triacylglycerol esterification

scientific article published on 19 December 2006

Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance

scientific article published on 10 December 2008

Overexpression of manganese superoxide dismutase ameliorates high-fat diet-induced insulin resistance in rat skeletal muscle

scientific article

PPARalpha /gamma ragaglitazar eliminates fatty liver and enhances insulin action in fat-fed rats in the absence of hepatomegaly

scientific article

PPARδ agonists have opposing effects on insulin resistance in high fat-fed rats and mice due to different metabolic responses in muscle

scientific article

Peroxisome proliferator activated receptors, fatty acids and muscle insulin resistance

scientific article published on 01 January 2002

Peroxisome proliferator-activated receptor (PPAR) activation induces tissue-specific effects on fatty acid uptake and metabolism in vivo--a study using the novel PPARalpha/gamma agonist tesaglitazar

scientific article published in April 2004

Pioglitazone treatment activates AMP-activated protein kinase in rat liver and adipose tissue in vivo

scientific article published on February 2004

Prior thiazolidinedione treatment preserves insulin sensitivity in normal rats during acute fatty acid elevation: role of the liver

scientific article

Rosiglitazone Treatment Enhances Acute AMP-Activated Protein Kinase-Mediated Muscle and Adipose Tissue Glucose Uptake in High-Fat-Fed Rats

scientific article published on 01 October 2006

The evolution of insulin resistance in muscle of the glucose infused rat

scientific article

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