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List of works by Alexei Kharitonenkov

An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in mice

scientific article published on May 2013

Central Fibroblast Growth Factor 21 Browns White Fat via Sympathetic Action in Male Mice

scientific article published on 29 April 2015

Direct effects of FGF21 on glucose uptake in human skeletal muscle: implications for type 2 diabetes and obesity

scientific article published in March 2011

Discrete Aspects of FGF21 In Vivo Pharmacology Do Not Require UCP1.

scientific article published on 5 May 2015

FGF-21/FGF-21 receptor interaction and activation is determined by betaKlotho

scientific article published on April 2008

FGF21 attenuates lipolysis in human adipocytes - a possible link to improved insulin sensitivity

scientific article published on 5 May 2008

FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis

scientific article published on February 2012

Fibroblast growth factor 21 and thyroid hormone show mutual regulatory dependency but have independent actions in vivo

scientific article published on 24 February 2014

Fibroblast growth factor 21 controls glycemia via regulation of hepatic glucose flux and insulin sensitivity

scientific article published on 21 May 2009

Fibroblast growth factor 21 corrects obesity in mice

scientific article

Fibroblast growth factor 21 is not required for the antidiabetic actions of the thiazoladinediones

scientific article published on 29 May 2013

Fibroblast growth factor 21 is not required for the reductions in circulating insulin-like growth factor-1 or global cell proliferation rates in response to moderate calorie restriction in adult mice

scientific article

Fibroblast growth factor 21 limits lipotoxicity by promoting hepatic fatty acid activation in mice on methionine and choline-deficient diets

scientific article

Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis

scientific article

Fundamentals of FGF19 & FGF21 action in vitro and in vivo

scientific article (publication date: 2012)

Hepatic SIRT1 attenuates hepatic steatosis and controls energy balance in mice by inducing fibroblast growth factor 21.

scientific article

Integrated Regulation of Hepatic Metabolism by Fibroblast Growth Factor 21 (FGF21) in Vivo

scientific article published on June 28, 2011

LY2405319, an Engineered FGF21 Variant, Improves the Metabolic Status of Diabetic Monkeys

scientific article published on June 18, 2013

Molecular determinants of FGF-21 activity-synergy and cross-talk with PPARgamma signaling

scientific article published on January 2007

Naringenin prevents obesity, hepatic steatosis, and glucose intolerance in male mice independent of fibroblast growth factor 21.

scientific article published on 16 March 2015

Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State

scientific article published on August 3, 2010

Overexpression of β-Klotho in Adipose Tissue Sensitizes Male Mice to Endogenous FGF21 and Provides Protection From Diet-Induced Obesity

scientific article

The breadth of FGF21's metabolic actions are governed by FGFR1 in adipose tissue

scientific article published on 28 August 2012

The circulating metabolic regulator FGF21 is induced by prolonged fasting and PPARalpha activation in man.

scientific article

The effects of LY2405319, an FGF21 analog, in obese human subjects with type 2 diabetes

scientific article

The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21.

scientific article