List of works by Charles Ffrench-Constant

Adhesion molecules in the regulation of CNS myelination.

scientific article

Adhesion molecules in the stem cell niche--more than just staying in shape?

scientific article

Altered human oligodendrocyte heterogeneity in multiple sclerosis

scientific article published on 23 January 2019

Beta1-integrin signaling mediates premyelinating oligodendrocyte survival but is not required for CNS myelination and remyelination.

scientific article published in July 2006

Biomimicking Fiber Platform with Tunable Stiffness to Study Mechanotransduction Reveals Stiffness Enhances Oligodendrocyte Differentiation but Impedes Myelination through YAP-Dependent Regulation

scientific article published on 12 August 2020

CNS Myelin Sheath Lengths Are an Intrinsic Property of Oligodendrocytes

scientific article published on 26 August 2015

CNS axons retain their competence for myelination throughout life.

scientific article published in February 2004

Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration.

scientific article published on 12 July 2017

Contrasting effects of mitogenic growth factors on myelination in neuron-oligodendrocyte co-cultures

scientific article published on 01 April 2007

Corrigendum: Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration

scientific article published in Nature

Disc1 variation leads to specific alterations in adult neurogenesis ⬇️

scientific article

Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis

scientific article published on 12 November 2018

Downregulation of the microtubule associated protein tau impairs process outgrowth and myelin basic protein mRNA transport in oligodendrocytes

scientific article

Dynamic regulation of integrin activation by intracellular and extracellular signals controls oligodendrocyte morphology

scientific article

Endothelin signalling mediates experience-dependent myelination in the CNS

scientific article published on 28 October 2019

Enhancing central nervous system remyelination in multiple sclerosis

scientific article

Extracellular Matrix Regulation of Stem Cell Behavior

scientific article

Familial t(1;11) translocation is associated with disruption of white matter structural integrity and oligodendrocyte-myelin dysfunction

scientific article published on 03 September 2019

Fibronectin aggregation in multiple sclerosis lesions impairs remyelination

scientific article

Gelsolin dysfunction causes photoreceptor loss in induced pluripotent cell and animal retinitis pigmentosa models.

scientific article published on 16 August 2017

Hippocampal Neurogenesis Requires Cell-Autonomous Thyroid Hormone Signaling

scientific article published on 09 April 2020

Hypomyelinating leukodystrophies: translational research progress and prospects

scientific article

Identification of dystroglycan as a second laminin receptor in oligodendrocytes, with a role in myelination

scientific journal article

Identification of endothelin 2 as an inflammatory factor that promotes central nervous system remyelination

scientific article published on 21 March 2013

In vitro modeling of central nervous system myelination and remyelination

scientific article published on 19 August 2011

Individual axons regulate the myelinating potential of single oligodendrocytes in vivo

scientific article published on 31 August 2011

Individual oligodendrocytes have only a few hours in which to generate new myelin sheaths in vivo

scientific article

Inflammation stimulates myelination by transplanted oligodendrocyte precursor cells

scientific article published in September 2006

Integrin activation or alpha 9 expression allows retinal pigmented epithelial cell adhesion on Bruch's membrane in wet age-related macular degeneration

scientific article

Integrin activation promotes axon growth on inhibitory chondroitin sulfate proteoglycans by enhancing integrin signaling

scientific article published on April 2011

Intrinsic and adaptive myelination-A sequential mechanism for smart wiring in the brain.

scientific article

Laminin enhances the growth of human neural stem cells in defined culture media

scientific article

Laminin α2 controls mouse and human stem cell behaviour during midbrain dopaminergic neuron development

scientific article published on 29 August 2019

M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

scientific article published on 21 July 2013

Magnetic resonance imaging of functional Schwann cell transplants labelled with magnetic microspheres.

scientific article published on 25 January 2006

Microfiber drug/gene delivery platform for study of myelination

article

Myelin regeneration in multiple sclerosis: targeting endogenous stem cells

scientific article published on October 2011

Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling

scientific article

Neural stem cell quiescence comes to an un-sticky end

scientific article published on 01 July 2014

Neuregulin and BDNF induce a switch to NMDA receptor-dependent myelination by oligodendrocytes

scientific article

Oligodendrocyte-Neuron Myelinating Coculture

scientific article published on 01 January 2019

Oriented and sustained protein expression on biomimicking electrospun fibers for evaluating functionality of cells

scientific article published on 22 August 2020

PI 3-kinase delta enhances axonal PIP3 to support axon regeneration in the adult CNS

scientific article published on 17 June 2020

Regenerating CNS myelin - from mechanisms to experimental medicines.

scientific article published in November 2017

Regulation of neural progenitor proliferation and survival by beta1 integrins

scientific article

Retinoid X receptor gamma signaling accelerates CNS remyelination

scientific article

Retinoid X receptors as a potential avenue for regenerative medicine in multiple sclerosis

scientific article published on 01 April 2011

Role of the oligodendroglial cytoskeleton in differentiation and myelination

scientific article published on December 2009

Scaffold-Mediated Sustained, Non-viral Delivery of miR-219/miR-338 Promotes CNS Remyelination

scientific article published on 01 December 2018

Selective rab11 transport and the intrinsic regenerative ability of CNS axons. ⬇️

scientific article

Stem cell treatments and multiple sclerosis

scientific article published on 11 March 2010

Tenascin C and tenascin R similarly prevent the formation of myelin membranes in a RhoA-dependent manner, but antagonistically regulate the expression of myelin basic protein via a separate pathway

scientific article

The Matricellular Protein R-Spondin 2 Promotes Midbrain Dopaminergic Neurogenesis and Differentiation

scientific article published on 23 August 2018

The adult mouse subependymal zone regenerates efficiently in the absence of tenascin-C.

scientific article

The chemokine receptor CXCR2 controls positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration

scientific article (publication date: 9 August 2002)

The formation of paranodal spirals at the ends of CNS myelin sheaths requires the planar polarity protein Vangl2

scientific article published on 03 March 2020

The guanine nucleotide exchange factor Vav3 modulates oligodendrocyte precursor differentiation and supports remyelination in white matter lesions

scientific article published on 18 November 2018

The late response of rat subependymal zone stem and progenitor cells to stroke is restricted to directly affected areas of their niche.

scientific article published on 02 July 2013

The microenvironment of the embryonic neural stem cell: lessons from adult niches?

scientific article published on December 2007

The number of stem cells in the subependymal zone of the adult rodent brain is correlated with the number of ependymal cells and not with the volume of the niche

scientific article published on 7 September 2011

Translation of myelin basic protein mRNA in oligodendrocytes is regulated by integrin activation and hnRNP-K.

scientific article

Unconjugated bilirubin restricts oligodendrocyte differentiation and axonal myelination

scientific article

Use of induced pluripotent stem-cell technology to understand photoreceptor cytoskeletal dynamics in retinitis pigmentosa.

scientific article

VEGF preconditioning leads to stem cell remodeling and attenuates age-related decay of adult hippocampal neurogenesis

scientific article

beta1 integrin maintains integrity of the embryonic neocortical stem cell niche

scientific article (publication date: August 2009)

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