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List of works by Geoff Hale

1.9 A structure of the therapeutic antibody CAMPATH-1H fab in complex with a synthetic peptide antigen

scientific article

1.9 Å structure of the therapeutic antibody CAMPATH-1H fab in complex with a synthetic peptide antigen

A Novel Strategy To Reduce the Immunogenicity of Biological Therapies

article

A comparative study of reduced dose alemtuzumab in matched unrelated donor and related donor reduced intensity transplants.

scientific article published on 29 January 2015

A comparison of the biodistribution and biokinetics of (99m)Tc-anti-CD66 mAb BW 250/183 and (99m)Tc-anti-CD45 mAb YTH 24.5 with regard to suitability for myeloablative radioimmunotherapy

scientific article published on 22 February 2003

A humanized CD18 antibody can block function without cell destruction

scientific article

A mouse monoclonal antibody against Epstein-Barr virus envelope glycoprotein 350 prevents infection both in vitro and in vivo

scientific article published on 25 July 2006

A pilot study of combination anti-cytokine and anti-lymphocyte biological therapy in rheumatoid arthritis.

scientific article published on 19 February 2008

A therapeutic human IgG4 monoclonal antibody that depletes target cells in humans

scientific article published on 01 December 1996

Advantages of rat monoclonal antibodies

scientific article

Alemtuzumab (CAMPATH 1H) induction therapy in cadaveric kidney transplantation--efficacy and safety at five years.

scientific article published in June 2005

Alemtuzumab (CAMPATH-1H) for the treatment of acute rejection in kidney transplant recipients: long-term follow-up.

scientific article

Alemtuzumab (Campath-1H) for treatment of lymphoid malignancies in the age of nonmyeloablative conditioning?

scientific article

Alemtuzumab (Campath-1H) in allogeneic stem cell transplantation: where do we go from here?

scientific article published on 01 June 2004

Alemtuzumab in stem cell transplantation

scientific article

Allogeneic bone marrow transplantation without graft-v-host disease: true tolerance of graft against the host through depletion of donor T lymphocytes pregrafting in malignant and nonmalignant disorders

scientific article published on 01 February 1987

Allogeneic stem-cell transplantation using a reduced-intensity conditioning regimen has the capacity to produce durable remissions and long-term disease-free survival in patients with high-risk acute myeloid leukemia and myelodysplasia

scientific article published on 28 November 2005

Amidination of pyruvate dehydrogenase complex of Escherichia coli under denaturing conditions ⬇️

scientific article published on January 1, 1979

Anti-CD45 monoclonal antibody YAML568: A promising radioimmunoconjugate for targeted therapy of acute leukemia.

scientific article published in August 2006

Anti-TNFα Therapy Modulates the Phenotype of Peripheral Blood CD4+T Cells in Patients with Posterior Segment Intraocular Inflammation

scientific article published on 01 January 2004

Anti-adhesion Molecule Therapy as an Interventional Strategy

scientific article published on 01 November 1999

Anti-globulin responses to rat and humanized CAMPATH-1 monoclonal antibody used to treat transplant rejection

scientific article published on 01 November 1999

Appropriate targets for monoclonal antibodies in the induction of transplantation tolerance

scientific article

Autologous Transplantation with CD52 Monoclonal Antibody-Purged Marrow for Acute Lymphoblastic Leukemia: Long-Term Follow-Up

scientific article published on 01 May 1997

Availability of Campath-1 antibodies for bone marrow transplantation

scientific article published on 01 February 1995

Blood concentrations of alemtuzumab and antiglobulin responses in patients with chronic lymphocytic leukemia following intravenous or subcutaneous routes of administration

scientific article

Bone Marrow Transplantation for Patients with Chronic Myeloid Leukemia

article

Bone marrow transplantation for chronic myeloid leukemia with volunteer unrelated donors using ex vivo or in vivo T-cell depletion: major prognostic impact of HLA class I identity between donor and recipient

scientific article

Bone marrow transplantation for patients with chronic myeloid leukaemia: T-cell depletion with Campath-1 reduces the incidence of graft-versus-host disease but may increase the risk of leukaemic relapse

scientific article published on 01 May 1986

Bone marrow transplantation in beta-thalassemia major with prevention of graft-vs-host disease

scientific article published on 01 January 1988

CAMPATH IH ALLOWS LOW-DOSE CYCLOSPORINE MONOTHERAPY IN 31 CADAVERIC RENAL ALLOGRAFT RECIPIENTS

scientific article published on 01 November 1999

CAMPATH-1 antibodies in stem-cell transplantation

scientific article published on 01 January 2001

CAMPATH-1 monoclonal antibodies in bone marrow transplantation.

scientific article

CAMPATH-1 monoclonal antibody therapy in severe refractory autoimmune thrombocytopenic purpura

scientific article

CAMPATH-1H in inflammatory arthritis

scientific article published on 01 March 1993

CAMPATH-1H in multiple sclerosis

scientific article published on 01 July 1996

CAMPATH: from concept to clinic

scientific article

CD52 antibodies for prevention of graft-versus-host disease and graft rejection following transplantation of allogeneic peripheral blood stem cells

scientific article published on 01 July 2000

CD52 expression patterns in myeloma and the applicability of alemtuzumab therapy

scientific article published on 17 October 2006

CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells

scientific article

CD8+ lymphocytes do not mediate protection against acute superinfection 20 days after vaccination with a live attenuated simian immunodeficiency virus

scientific article

Campath-1 Abs 'in the bag' for hematological malignancies: the Cape Town experience

scientific article published on January 2004

Campath-1G causes rapid depletion of circulating host dendritic cells (DCs) before allogeneic transplantation but does not delay donor DC reconstitution

scientific article published on 01 April 2002

Campath-1G in vivo confers a low incidence of graft-versus-host disease associated with a high incidence of mixed chimaerism after bone marrow transplantation for severe aplastic anaemia using HLA-identical sibling donors

scientific article published on 01 May 1996

Campath-1H therapy in refractory ocular inflammatory disease

scientific article published on January 2000

Campath-1M--prophylactic use after kidney transplantation. A randomized controlled clinical trial

scientific article published on 01 August 1989

Cell Banks and Stability of Antibody Production ⬇️

scientific article published on 01 January 2000

Cell-to-cell transfer of glycosylphosphatidylinositol-anchored membrane proteins during sperm maturation ⬇️

scientific article (publication date: March 1996)

Characterization of the CAMPATH-1 (CDw52) antigen: biochemical analysis and cDNA cloning reveal an unusually small peptide backbone

scientific article

Children with acute lymphoblastic leukemia who receive T-cell-depleted HLA mismatched marrow allografts from unrelated donors have an increased incidence of primary graft failure but a similar overall transplant outcome.

scientific article

Clinical evidence of a graft-versus-Hodgkin's-lymphoma effect after reduced-intensity allogeneic transplantation

scientific article published in June 2005

Clinical trials with CAMPATH-I and other monoclonal antibodies

scientific article published on November 1995

Comparison of allogeneic T cell-depleted peripheral blood stem cell and bone marrow transplantation: effect of stem cell source on short- and long-term outcome

scientific article published on 01 May 2001

Complement activation by immunoglobulin does not depend solely on C1q binding

scientific article published on 01 February 1990

Control of graft-versus-host disease and graft rejection by T cell depletion of donor and recipient with Campath-1 antibodies. Results of matched sibling transplants for malignant diseases.

scientific article published in May 1994

Crystal structures of a rat anti-CD52 (CAMPATH-1) therapeutic antibody Fab fragment and its humanized counterpart

scientific article

Double T cell depletion of bone marrow using sequential positive and negative cell immunoaffinity or CD34+ cell selection followed by Campath-1M; effect on CD34+ cells and progenitor cell recoveries

scientific article

EFFECT OF GRAFT PERFUSION WITH TWO CD45 MONOCLONAL ANTIBODIES ON INCIDENCE OF KIDNEY ALLOGRAFT REJECTION

scientific article published in The Lancet

EX VIVO DEPLETION OF T CELLS FROM BONE MARROW GRAFTS WITH CAMPATH-1 IN ACUTE LEUKEMIA

article published in 1999

Effects of CAMPATH-1 antibodies in vivo in patients with lymphoid malignancies: influence of antibody isotype

scientific article published on 01 May 1989

Effects of monoclonal anti-lymphocyte antibodies in vivo in monkeys and humans

scientific article published on 01 October 1983

Efficient complement-mediated lysis of cells containing the CAMPATH-1 (CDw52) antigen

scientific article published on 01 August 1993

Elimination of graft-versus-host disease by in-vitro depletion of alloreactive lymphocytes with a monoclonal rat anti-human lymphocyte antibody (CAMPATH-1).

scientific article

Elimination of the immunogenicity of therapeutic antibodies

scientific article published on March 1999

Engraftment of marrow allografts treated with Campath-1 monoclonal antibodies

scientific article published on 01 July 1999

Epstein-Barr virus (EBV) associated B-cell lymphoproliferative disease following HLA identical sibling marrow transplantation for aplastic anaemia in a patient with an EBV seronegative donor

scientific article published in May 1999

Ex vivo T-cell depletion with the monoclonal antibody Campath-1 plus human complement effectively prevents acute graft-versus-host disease in allogeneic bone marrow transplantation

scientific article published on 01 November 1986

Ex vivo depletion of T cells from bone marrow grafts with CAMPATH-1 in acute leukemia: graft-versus-host disease and graft-versus-leukemia effect

Ex-vivo whole blood cultures for predicting cytokine-release syndrome: dependence on target antigen and antibody isotype

scientific article published on 01 August 1995

Excessive T cell depletion of peripheral blood stem cells has an adverse effect upon outcome following allogeneic stem cell transplantation

scientific article published on 01 November 2001

Favorable effect on acute and chronic graft-versus-host disease with cyclophosphamide and in vivo anti-CD52 monoclonal antibodies for marrow transplantation from HLA-identical sibling donors for acquired aplastic anemia

scientific article published on 01 December 2004

Fractionation of bovine serum albumin and monoclonal antibody alemtuzumab using carrier phase ultrafiltration

scientific article published in May 2005

From Laboratory to Clinic : The Story of CAM PA TH-1

scientific article

Haemopoietic stem-cell transplantation with antibody-based minimal-intensity conditioning: a phase 1/2 study

scientific article published on 2 September 2009

High incidence of cytomegalovirus infection after nonmyeloablative stem cell transplantation: potential role of Campath-1H in delaying immune reconstitution

scientific article published on 01 June 2002

Human CD3 Transgenic Mice: Preclinical Testing of Antibodies Promoting Immune Tolerance

scientific article published on 01 February 2011

Human monoclonal IgG isotypes differ in complement activating function at the level of C4 as well as C1q.

scientific article published on July 1988

Humanised monoclonal antibody therapy for rheumatoid arthritis

scientific article published in The Lancet

Humanized anti-CD4 monoclonal antibody therapy of autoimmune and inflammatory disease

scientific article

Humanized monoclonal antibody treatment in rheumatoid arthritis

scientific article published in November 1991

IMMUNE RECONSTITUTION AFTER ALLOGENEIC BONE MARROW TRANSPLANTATION DEPLETED OF T CELLS

scientific article published on 01 April 2000

Immune reconstitution at 6 months following T-cell depleted hematopoietic stem cell transplantation is predictive for treatment outcome

scientific article

Immunohematopoietic stem cell transplantation in Cape Town: a ten-year outcome analysis in adults.

scientific article published in January 2009

Impact of in vivo alemtuzumab dose before reduced intensity conditioning and HLA-identical sibling stem cell transplantation: pharmacokinetics, GVHD, and immune reconstitution

scientific article published on 29 June 2010

Impact on T-cell depletion and CD34+ cell recovery using humanised CD52 monoclonal antibody (CAMPATH-1H) in BM and PSBC collections; comparison with CAMPATH-1M and CAMPATH-1G

scientific article published on 01 January 2000

Importance of antigen specificity for complement-mediated lysis by monoclonal antibodies.

scientific article

Improving the outcome of bone marrow transplantation by using CD52 monoclonal antibodies to prevent graft-versus-host disease and graft rejection

scientific article published in December 1998

In vitro and in vivo depletion of T cells.

scientific article published in January 1993

In vivo 'Purging' of residual disease in CLL with Campath-1H

scientific article published on 01 June 1997

In vivo CAMPATH-1H prevents GvHD following nonmyeloablative stem-cell transplantation

scientific article published in January 2001

In vivo CAMPATH-1H prevents graft-versus-host disease following nonmyeloablative stem cell transplantation

scientific article published on 01 October 2000

In vivo use of Campath-1G to prevent graft-versus-host disease and graft rejection after bone marrow transplantation

scientific article published on 01 April 1992

Incidence and outcome of adenovirus disease in transplant recipients after reduced-intensity conditioning with alemtuzumab

scientific article published in March 2004

Inhibition of pyruvate dehydrogenase multienzyme complex from Escherichia coli with mono- and bifunctional arsenoxides ⬇️

scientific article published on May 30, 1978

Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes

scientific article

Interaction of rat monoclonal antibodies with human killer cells

Interaction of rat monoclonal antibodies with human killer cells (K cells)

scientific article published in 1984

Isolation of low-frequency class-switch variants from rat hybrid myelomás

scientific article published on 01 October 1987

Leukaemic relapse after Campath 1-treated bone-marrow transplantation for leukaemia

scientific article published on 01 January 1987

Limited Proteolysis of the Pyruvate Dehydrogenase Multienzyme Complex of Escherichia coli ⬇️

scientific article published on February 15, 1979

Limiting transplantation-related mortality following unrelated donor stem cell transplantation by using a nonmyeloablative conditioning regimen

scientific article published in February 2002

Local bioactive tumour necrosis factor (TNF) in corneal allotransplantation

scientific article published on 01 October 2000

Long-term remission of intractable systemic vasculitis with monoclonal antibody therapy

scientific article published in The Lancet

Long-term survival after lymphocytotoxic monoclonal antibody therapy for rheumatoid arthritis.

scientific article published on 17 February 2005

Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis

scientific article published in November 2005

Matched unrelated donor bone marrow transplantation for chronic myeloid leukaemia in chronic phase: comparison of ex vivo and in vivo T-cell depletion.

scientific article published in January 1993

Measurement of Endotoxin ⬇️

scientific article published on 01 January 2000

Measurement of antibody concentrations by hemagglutination

scientific article published on January 1, 2000

Mechanism of first-dose cytokine-release syndrome by CAMPATH 1-H: involvement of CD16 (FcgammaRIII) and CD11a/CD18 (LFA-1) on NK cells

scientific article

Mechanisms of Antibody Immunotherapy on Clonal Islet Reactive T Cells

scientific article published on 07 April 2006

Methods to measure the binding of therapeutic monoclonal antibodies to the human Fc receptor FcγRIII (CD16) using real time kinetic analysis and flow cytometry ⬇️

scientific article published on January 30, 2012

Molecular weight and symmetry of the pyruvate dehydrogenase multienzyme complex of Escherichia coli ⬇️

scientific article published on April 25, 1979

Monoclonal antibodies for immunosuppression

scientific article published on January 1988

Monoclonal antibodies to haemopoietic cells

Monoclonal antibody therapy of chronic intraocular inflammation using Campath-1H.

scientific article published on November 1995

Monoclonal antibody therapy of diffuse cutaneous scleroderma with CAMPATH-1H.

scientific article published on June 1996

Monoclonal antibody treatment exposes three mechanisms underlying the clinical course of multiple sclerosis

scientific article (publication date: September 1999)

Monoclonal-Antibody Therapy in Systemic Vasculitis

scientific article published on 01 July 1990

Morbidity and mortality in rheumatoid arthritis patients with prolonged and profound therapy-induced lymphopenia

scientific article

Morbidity and mortality in rheumatoid arthritis patients with prolonged therapy-induced lymphopenia: twelve-year outcomes

scientific article published on February 2008

Myeloablative conditioning is well tolerated by older patients receiving T-cell-depleted grafts

scientific article

Neutralizing TNF-alpha activity modulates T-cell phenotype and function in experimental autoimmune uveoretinitis

scientific article published in June 1998

Neutralizing tumor necrosis factor activity leads to remission in patients with refractory noninfectious posterior uveitis

scientific article published in June 2004

Non-size-based membrane chromatographic separation and analysis of monoclonal antibody aggregates

scientific article published in October 2006

Outcomes after myeloablative unrelated donor stem cell transplantation using both in vitro and in vivo T-cell depletion with alemtuzumab

scientific article published on 01 November 2006

P1. Immunoablation with t cell depleted autologous peripheral blood stem cell rescue produces complete remission in thrombocytopenic purpura (TTP) recidivant and refractory to standard treatment

PHASE I STUDY OF AN ENGINEERED AGLYCOSYLATED HUMANIZED CD3 ANTIBODY IN RENAL TRANSPLANT REJECTION1

scientific article published on 01 December 1999

Parameter scanning ultrafiltration: rapid optimisation of protein separation

scientific article published on 01 March 2003

Pediatric immunohematopoietic stem cell transplantation at a tertiary care center in Cape Town

scientific article

Pharmacokinetics and antibody responses to the CD3 antibody otelixizumab used in the treatment of type 1 diabetes.

scientific article published on 10 February 2010

Pharmacokinetics of CAMPATH-1H: assay development and validation

scientific article published on February 2002

Pharmacokinetics of alemtuzumab used for in vivo and in vitro T-cell depletion in allogeneic transplantations: relevance for early adoptive immunotherapy and infectious complications

scientific article published on 06 March 2003

Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath-1H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL).

scientific article

Pilot study of CAMPATH-1, a rat monoclonal antibody that fixes human complement, as an immunosuppressant in organ transplantation

scientific article published on 01 September 1986

Polypeptide-chain stoicheiometry and lipoic acid content of the pyruvate dehydrogenase complex of Escherichia coli ⬇️

scientific article published on January 1, 1979

Preclinical development of monoclonal antibodies: considerations for the use of non-human primates

scientific article

Preliminary evidence from magnetic resonance imaging for reduction in disease activity after lymphocyte depletion in multiple sclerosis

scientific article published in July 1994

Preliminary experience of allogeneic stem cell transplantation for lymphoproliferative disorders using BEAM-CAMPATH conditioning: an effective regimen with low procedure-related toxicity

article

Prevention of immune-mediated corneal graft destruction with the anti-lymphocyte monoclonal antibody, CAMPATH-1H

scientific article published on 01 January 1995

Primary structure of the swinging arms of the pyruvate dehydrogenase complex of Escherichia coli ⬇️

scientific article published on September 15, 1979

Prope tolerance with induction using Campath 1H and low-dose cyclosporin monotherapy in 31 cadaveric renal allograft recipients

scientific article published on 01 March 2000

Prope tolerance, perioperative campath 1H, and low-dose cyclosporin monotherapy in renal allograft recipients

scientific article published in The Lancet

Prophylactic use of an antilymphocyte monoclonal antibody following renal transplantation: a randomized controlled trial

scientific article published on 01 February 1987

Pulsed monoclonal antibody treatment and autoimmune thyroid disease in multiple sclerosis

scientific article published in The Lancet

Purging in auto- and allografts: monoclonal antibodies which use human complement and other natural effector mechanisms

scientific article published on 01 January 1990

Quality Control of Raw Materials ⬇️

scientific article published on 01 January 2000

Quantitation of minimal disease levels in chronic lymphocytic leukemia using a sensitive flow cytometric assay improves the prediction of outcome and can be used to optimize therapy

scientific article published on July 2001

REMISSION INDUCTION IN NON-HODGKIN LYMPHOMA WITH RESHAPED HUMAN MONOCLONAL ANTIBODY CAMPATH-1H

scientific article published in The Lancet

Radiotherapy-based conditioning is effective immunosuppression for patients undergoing transplantation with T-cell depleted stem cell grafts for severe aplasia

scientific article published in January 2004

Rat monoclonal antibodies for bone marrow transplantation--the CAMPATH series

scientific article published on 01 January 1985

Reactivity of rat monoclonal antibody CAMPATH-1 with human leukaemia cells and its possible application for autologous bone marrow transplantation

scientific article

Recent results using CAMPATH-1 antibodies to control GVHD and graft rejection

scientific article published on 01 March 1996

Reconstitution of the Epstein-Barr virus-specific cytotoxic T-lymphocyte response following T-cell-depleted myeloablative and nonmyeloablative allogeneic stem cell transplantation

scientific article published in August 2003

Reduced-intensity transplantation with in vivo T-cell depletion and adjuvant dose-escalating donor lymphocyte infusions for chemotherapy-sensitive myeloma: Limited efficacy of graft-versus-tumor activity

scientific article published on 01 April 2003

Remission Induction in Patients with Lymphoid Malignancies Using Unconjugated CAMPATH-1 Monoclonal Antibodies.

scientific article published on January 1990

Remission induction in Behçet's disease following lymphocyte depletion by the anti-CD52 antibody CAMPATH 1-H.

scientific article published on 29 August 2003

Removal of T cells from bone marrow for transplantation. Comparison of rat monoclonal anti-lymphocyte antibodies of different isotypes

scientific article published on 01 October 1983

Removal of T cells from bone marrow for transplantation: a monoclonal antilymphocyte antibody that fixes human complement

scientific article

Reprogramming the immune system: a possible therapeutic approach to established autoimmune disease

scientific article published on 01 March 1993

Respiratory virus infections in adult T cell-depleted transplant recipients: the role of cellular immunity ⬇️

scientific article published on October 27, 2001

Respiratory virus infections in transplant recipients after reduced-intensity conditioning with Campath-1H: high incidence but low mortality

scientific article published in December 2002

Reversal of allograft rejection using the monoclonal antibody, Campath-1G

scientific article published on 01 August 1991

Risks of developing Epstein-Barr virus-related lymphoproliferative disorders after T-cell-depleted marrow transplants. CAMPATH Users.

scientific article published in April 1998

Selective apoptotic killing of malignant hemopoietic cells by antibody-targeted delivery of an amphipathic peptide

scientific article

Self-assembly and catalytic activity of the pyruvate dehydrogenase multienzyme complex of Escherichia coli ⬇️

scientific article published on July 28, 1977

Semi-specific immuno-absorption and monoclonal antibody therapy in ANCA positive vasculitis: experience in four cases

scientific article

Separation of monoclonal antibody alemtuzumab monomer and dimers using ultrafiltration

scientific article published in May 2005

Specificity of monoclonal antibody Campath-1

scientific article published on 01 May 1988

Structure of the CAMPATH-1 antigen, a glycosylphosphatidylinositol-anchored glycoprotein which is an exceptionally good target for complement lysis

scientific article published on August 1993

Subunit exchange in the pyruvate dehydrogenase complex ofEscherichia coli ⬇️

scientific article published on August 15, 1979

Successful haploidentical mismatched bone marrow transplantation in severe combined immunodeficiency: T cell removal using CAMPATH-I monoclonal antibody and E-rosetting

scientific article published on 01 March 1986

Successful treatment of renal allograft rejection with a humanized antilymphocyte monoclonal antibody

scientific article published on 01 February 1995

Sustained remission of severe resistant autoimmune neutropenia with Campath-1H

scientific article published on 01 May 1997

Synergistic complement lysis by monoclonal antibodies to the human leukocyte common antigen requires both the classical and alternative pathways

scientific article published on 01 June 1987

Synthetic peptide mimotope of the CAMPATH-1 (CD52) antigen, a small glycosylphosphatidylinositol-anchored glycoprotein ⬇️

scientific article published on December 1, 1995

T cell depletion by exposure to Campath-1G in vitro prevents graft-versus-host disease

scientific article

T cell depletion of allogeneic peripheral blood stem cells ⬇️

scientific article published on 01 February 1998

T cell depletion with CAMPATH-1 in allogeneic bone marrow transplantation

scientific article published on 01 April 1988

T- and B-cell immune reconstitution and clinical outcome in patients with multiple myeloma receiving T-cell-depleted, reduced-intensity allogeneic stem cell transplantation with an alemtuzumab-containing conditioning regimen followed by escalated don

scientific article published on 01 October 2003

T-cell depletion with Campath-1H 'in the bag' for matched related allogeneic peripheral blood stem cell transplantation is associated with reduced graft-versus-host disease, rapid immune constitution and improved survival

scientific article published on 01 April 2003

THERAPEUTIC POTENTIAL OF MONOCLONAL ANTIBODIES TO THE LEUKOCYTE-COMMON ANTIGEN

scientific article published on 01 November 1985

The CAMPATH-1 antigen (CDw52)

scientific article published on 01 March 1990

The Dog That Hasn't Barked: The Political Economy of Contemporary Debates on Canadian Foreign Investment Policies

article

The PNH phenotype cells that emerge in most patients after CAMPATH-1H therapy are present prior to treatment.

scientific article published in October 1999

The effect of the serotherapy regimen used and the marrow cell dose received on rejection, graft-versus-host disease and outcome following unrelated donor bone marrow transplantation for leukaemia.

scientific article published in February 2000

The effect of treatment with Campath-1H in patients with autoimmune cytopenias

scientific article

The improved lytic function andin vivo efficacy of monovalent monoclonal CD3 antibodies

scientific article published on 01 February 1989

The relationship between pityriasis rubra pilaris and inflammatory arthritis: Case report and response of the arthritis to anti-tumor necrosis factor immunotherapy

article

The repopulation capacity of bone marrow grafts following pretreatment with monoclonal antibodies against T lymphocytes in rhesus monkeys

scientific article published on 01 February 1988

The window of therapeutic opportunity in multiple sclerosis: evidence from monoclonal antibody therapy

scientific article published on 27 July 2005

Therapeutic antibodies--delivering the promise?

scientific article published on 22 May 2006

Therapeutic potential of monoclonal antibodies to the leucocyte common antigen

scientific article published on 01 January 1985

Therapeutic potential of rat monoclonal antibodies: isotype specificity of antibody-dependent cell-mediated cytotoxicity with human lymphocytes

scientific article published in May 1985

Transient Epstein-Barr virus reactivation in CD3 monoclonal antibody-treated patients

scientific article published on 09 December 2009

Transient increase in symptoms associated with cytokine release in patients with multiple sclerosis

scientific article published in February 1996

Treatment of corneal ulcers in dogs

scientific article published in January 2006

Treatment of refractory Wegener's granulomatosis with humanized monoclonal antibodies

scientific article published on 01 December 1996

Ultrafast Separation and Analysis of Monoclonal Antibody Aggregates Using Membrane Chromatography

scientific article published on 27 March 2017

Unrelated donor bone marrow transplant in childhood ALL. The role of T-cell depletion

Unrelated donor bone marrow transplantation for children with relapsed acute lymphoblastic leukaemia in second complete remission

scientific article published on 01 September 1996

Use of Ceprate CD34-positive selection system for depletion of T cells in allogeneic transplantation ⬇️

scientific article published on 01 October 1997

What can be done to prevent graft versus host disease?

scientific article published on October 1994

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