List of works by Cinzia Fionda

15-deoxy-Delta12,14-prostaglandin J2 negatively regulates rankl gene expression in activated T lymphocytes: role of NF-kappaB and early growth response transcription factors

scientific article published on 01 April 2007

ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype

scientific article

Activation of liver X receptor up-regulates the expression of the NKG2D ligands MICA and MICB in multiple myeloma through different molecular mechanisms

scientific article published on 24 May 2019

Bone Marrow Stromal Cell-Derived IL-8 Upregulates PVR Expression on Multiple Myeloma Cells via NF-kB Transcription Factor

scientific article published on 13 February 2020

CD155: A Multi-Functional Molecule in Tumor Progression

scientific article published on 30 January 2020

Chemotherapy-elicited upregulation of NKG2D and DNAM-1 ligands as a therapeutic target in multiple myeloma.

scientific article published on 22 October 2013

Drug-induced senescent Multiple Myeloma cells elicit NK cell proliferation by direct or exosome-mediated IL-15 trans-presentation.

scientific article published on 24 April 2018

Genotoxic Stress Induces Senescence-Associated ADAM10-Dependent Release of NKG2D MIC Ligands in Multiple Myeloma Cells.

scientific article published on 12 June 2015

Genotoxic stress modulates the release of exosomes from multiple myeloma cells capable of activating NK cell cytokine production: Role of HSP70/TLR2/NF-kB axis.

scientific article published on 13 January 2017

Heat shock protein-90 inhibitors increase MHC class I-related chain A and B ligand expression on multiple myeloma cells and their ability to trigger NK cell degranulation

scientific article

Hitting More Birds with a Stone: Impact of TGF-β on ILC Activity in Cancer

scientific article published on 05 January 2020

Hyperthermia enhances CD95-ligand gene expression in T lymphocytes

scientific article published on January 2005

IL-15 inhibits IL-7Rα expression by memory-phenotype CD8⁺ T cells in the bone marrow.

scientific article published in May 2012

Immunoregulatory and Effector Activities of Nitric Oxide and Reactive Nitrogen Species in Cancer

scientific article

Impact of bone marrow-derived signals on NK cell development and functional maturation.

scientific article published on 27 March 2018

Inhibition of bromodomain and extra-terminal (BET) proteins increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role of cMYC-IRF4-miR-125b interplay

scientific article published on December 2016

Inhibition of glycogen synthase kinase-3 increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role of STAT3.

scientific article published on 17 May 2013

Inhibition of trail gene expression by cyclopentenonic prostaglandin 15-deoxy-delta12,14-prostaglandin J2 in T lymphocytes.

scientific article

Innate immune activating ligand SUMOylation affects tumor cell recognition by NK cells.

scientific article

JAK/STAT signaling in regulation of innate lymphoid cells: The gods before the guardians

scientific article published on 01 November 2018

Key Role of the CD56CD16 Natural Killer Cell Subset in the Recognition and Killing of Multiple Myeloma Cells

MICA-129 Dimorphism and Soluble MICA Are Associated With the Progression of Multiple Myeloma.

scientific article published in May 2018

NK Cell Reconstitution in Paediatric Leukemic Patients after T-Cell-Depleted HLA-Haploidentical Haematopoietic Stem Cell Transplantation Followed by the Reinfusion of iCasp9-Modified Donor T Cells

scientific article published on 07 November 2019

NKG2D and DNAM-1 Ligands: Molecular Targets for NK Cell-Mediated Immunotherapeutic Intervention in Multiple Myeloma

scientific article

NKG2D and Its Ligands: "One for All, All for One".

scientific article

Natural Killer Cell Response to Chemotherapy-Stressed Cancer Cells: Role in Tumor Immunosurveillance.

scientific article published on 25 September 2017

Negative regulation of CD95 ligand gene expression by vitamin D3 in T lymphocytes

scientific article published in February 2002

Negative regulation of innate lymphoid cell responses in inflammation and cancer

scientific article published on 31 January 2019

Nitric oxide donors increase PVR/CD155 DNAM-1 ligand expression in multiple myeloma cells: role of DNA damage response activation.

scientific article published on 22 January 2015

Oxidative stress inhibits IFN-alpha-induced antiviral gene expression by blocking the JAK-STAT pathway.

scientific article published on 9 March 2006

Reactive oxygen species- and DNA damage response-dependent NK cell activating ligand upregulation occurs at transcriptional levels and requires the transcriptional factor E2F1.

scientific article

Reconstitution of multifunctional CD56lowCD16low natural killer cell subset in children with acute leukemia given α/β T cell-depleted HLA-haploidentical haematopoietic stem cell transplantation.

scientific article published on 10 August 2017

Role of Distinct Natural Killer Cell Subsets in Anticancer Response

scientific article published on 16 March 2017

Targeting NKG2D and NKp30 Ligands Shedding to Improve NK Cell-Based Immunotherapy.

scientific article published in January 2016

The Cyclopentenone-Type Prostaglandin 15-Deoxy-Δ12,14-Prostaglandin J2 Inhibits CD95 Ligand Gene Expression in T Lymphocytes: Interference with Promoter Activation Via Peroxisome Proliferator-Activated Receptor-γ-Independent Mechanisms ⬇️

scientific article published on May 1, 2003

The DNA Damage Response: A Common Pathway in the Regulation of NKG2D and DNAM-1 Ligand Expression in Normal, Infected, and Cancer Cells.

scientific article published on 07 January 2014

The IMiDs targets IKZF-1/3 and IRF4 as novel negative regulators of NK cell-activating ligands expression in multiple myeloma

scientific article

The POU-Domain Transcription Factor Oct-6/POU3F1 as a Regulator of Cellular Response to Genotoxic Stress

scientific article published on 11 June 2019

The Ubiquitin-proteasome pathway regulates Nectin2/CD112 expression and impairs NK cell recognition and killing

scientific article published on 27 March 2019

The homeobox transcription factor MEIS2 is a regulator of cancer cell survival and IMiDs activity in Multiple Myeloma: modulation by Bromodomain and Extra-Terminal (BET) protein inhibitors

scientific article published on 11 April 2019

Translating the anti-myeloma activity of Natural Killer cells into clinical application

scientific article published on 10 October 2018

Ubiquitin-dependent endocytosis of NKG2D-DAP10 receptor complexes activates signaling and functions in human NK cells.

scientific article published on 27 October 2015

p38 MAPK differentially controls NK activating ligands at transcriptional and post-transcriptional level on multiple myeloma cells.

scientific article published on 2 December 2016

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