List of works - Leon Flicker

Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: a randomized trial

scientific article

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

scientific article

Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials

scientific article

One year follow-up study of the association between chemical castration, sex hormones, beta-amyloid, memory and depression in men.

scientific article

Lower testosterone levels predict incident stroke and transient ischemic attack in older men.

scientific article published on 7 April 2009

Calcium supplementation and the risks of atherosclerotic vascular disease in older women: results of a 5-year RCT and a 4.5-year follow-up

article by Joshua R Lewis et al published January 2011 in Journal of Bone and Mineral Research

Body mass index and survival in men and women aged 70 to 75.

scientific article

Low free testosterone predicts frailty in older men: the health in men study

scientific article published on 21 April 2010

Homocysteine and depression in later life

scientific article

Reduced serum total osteocalcin is associated with metabolic syndrome in older men via waist circumference, hyperglycemia, and triglyceride levels

scientific article published on 25 May 2010

Reporting standards for studies of diagnostic test accuracy in dementia: The STARDdem Initiative

scientific article

Cohort Profile: The Health In Men Study (HIMS).

scientific article published on 3 March 2008

Smoking is associated with reduced cortical regional gray matter density in brain regions associated with incipient Alzheimer disease

scientific article published in January 2008

In older men an optimal plasma testosterone is associated with reduced all-cause mortality and higher dihydrotestosterone with reduced ischemic heart disease mortality, while estradiol levels do not predict mortality

scientific article

Falls, depression and antidepressants in later life: a large primary care appraisal

scientific article

Factors associated with suicidal thoughts in a large community study of older adults

scientific article published in December 2012

Low free testosterone predicts mortality from cardiovascular disease but not other causes: the Health in Men Study

scientific article

Factors associated with self and informant ratings of the quality of life of people with dementia living in care facilities: a cross sectional study

scientific article

Smoking as a risk factor for Alzheimer's disease: contrasting evidence from a systematic review of case-control and cohort studies

scientific article (publication date: 2002)

Reference ranges and determinants of testosterone, dihydrotestosterone, and estradiol levels measured using liquid chromatography-tandem mass spectrometry in a population-based cohort of older men.

scientific article published on 13 September 2012

Cognitive and brain changes associated with ischaemic heart disease and heart failure

scientific article published on 31 January 2012

A 20-week randomized controlled trial of estradiol replacement therapy for women aged 70 years and older: effect on mood, cognition and quality of life

scientific article published on 16 March 2005

Low free testosterone concentration as a potentially treatable cause of depressive symptoms in older men.

scientific article published in March 2008

Plasma and cerebrospinal fluid amyloid beta for the diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI)

scientific article

Lower sex hormone-binding globulin is more strongly associated with metabolic syndrome than lower total testosterone in older men: the Health in Men Study

scientific article published in June 2008

Community-based exercise program reduces risk factors for falls in 65- to 75-year-old women with osteoporosis: randomized controlled trial.

scientific article

Fall rates in hospital rehabilitation units after individualised patient and staff education programmes: a pragmatic, stepped-wedge, cluster-randomised controlled trial

scientific article published on 9 April 2015

Association Between Lifestyle Factors and Mental Health Measures Among Community-Dwelling Older Women

article

Lower serum testosterone is independently associated with insulin resistance in non-diabetic older men: the Health In Men Study

scientific article published on 6 August 2009

In men older than 70 years, total testosterone remains stable while free testosterone declines with age. The Health in Men Study

scientific article

The association of C-reactive protein and CRP genotype with coronary heart disease: findings from five studies with 4,610 cases amongst 18,637 participants

scientific article published on 20 August 2008

Higher serum undercarboxylated osteocalcin and other bone turnover markers are associated with reduced diabetes risk and lower estradiol concentrations in older men.

scientific article published in January 2015

Effects of anticholinergic drugs on cognitive function in older Australians: results from the AIBL study

scientific article published on 9 March 2011

Physical activity and all-cause mortality in older women and men.

scientific article published on 4 January 2012

Falls, injuries from falls, health related quality of life and mortality in older adults with vision and hearing impairment--is there a gender difference?

scientific article published on 12 June 2011

Quality use of medicines and health outcomes among a cohort of community dwelling older men: an observational study

scientific article

150 minutes of vigorous physical activity per week predicts survival and successful ageing: a population-based 11-year longitudinal study of 12 201 older Australian men.

scientific article published on 3 September 2013

Successful mental health aging: results from a longitudinal study of older Australian men.

scientific article published in January 2006

24-month effect of smoking cessation on cognitive function and brain structure in later life

scientific article

Association of Cardiovascular Risk Factors and Disease With Depression in Later Life

scientific article published on 08 December 2006

Systematic review of the body of evidence for the use of biomarkers in the diagnosis of dementia.

scientific article

Patterns of dietary intake and psychological distress in older Australians: benefits not just from a Mediterranean diet

scientific article published on 3 December 2012

Deprescribing in Frail Older People: A Randomised Controlled Trial

scientific article

Obesity and metabolic syndrome increase the risk of incident depression in older men: the health in men study

scientific article published in October 2009

B-vitamins reduce the long-term risk of depression after stroke: The VITATOPS-DEP trial

scientific article

Contribution of the MTHFR gene to the causal pathway for depression, anxiety and cognitive impairment in later life

scientific article published in February 2005

Anxiety, depression, and comorbid anxiety and depression: risk factors and outcome over two years

scientific article published on 12 June 2012

Polymorphisms of the CRP gene inhibit inflammatory response and increase susceptibility to depression: the Health in Men Study

scientific article published on 11 May 2009

Systematic review and meta-analysis of randomized placebo-controlled trials of folate and vitamin B12 for depression

scientific article

Effectiveness of a smoking cessation intervention in older adults

scientific article published in January 2007

List of works by Leon Flicker

Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: a randomized trial

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials

One year follow-up study of the association between chemical castration, sex hormones, beta-amyloid, memory and depression in men.

Lower testosterone levels predict incident stroke and transient ischemic attack in older men.

Calcium supplementation and the risks of atherosclerotic vascular disease in older women: results of a 5-year RCT and a 4.5-year follow-up

Body mass index and survival in men and women aged 70 to 75.

Low free testosterone predicts frailty in older men: the health in men study

Homocysteine and depression in later life

Reduced serum total osteocalcin is associated with metabolic syndrome in older men via waist circumference, hyperglycemia, and triglyceride levels

Reporting standards for studies of diagnostic test accuracy in dementia: The STARDdem Initiative

Cohort Profile: The Health In Men Study (HIMS).

Smoking is associated with reduced cortical regional gray matter density in brain regions associated with incipient Alzheimer disease

In older men an optimal plasma testosterone is associated with reduced all-cause mortality and higher dihydrotestosterone with reduced ischemic heart disease mortality, while estradiol levels do not predict mortality

Falls, depression and antidepressants in later life: a large primary care appraisal

Factors associated with suicidal thoughts in a large community study of older adults

Low free testosterone predicts mortality from cardiovascular disease but not other causes: the Health in Men Study

Factors associated with self and informant ratings of the quality of life of people with dementia living in care facilities: a cross sectional study

Smoking as a risk factor for Alzheimer's disease: contrasting evidence from a systematic review of case-control and cohort studies

Reference ranges and determinants of testosterone, dihydrotestosterone, and estradiol levels measured using liquid chromatography-tandem mass spectrometry in a population-based cohort of older men.

Cognitive and brain changes associated with ischaemic heart disease and heart failure

A 20-week randomized controlled trial of estradiol replacement therapy for women aged 70 years and older: effect on mood, cognition and quality of life

Low free testosterone concentration as a potentially treatable cause of depressive symptoms in older men.

Plasma and cerebrospinal fluid amyloid beta for the diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI)

Lower sex hormone-binding globulin is more strongly associated with metabolic syndrome than lower total testosterone in older men: the Health in Men Study

Community-based exercise program reduces risk factors for falls in 65- to 75-year-old women with osteoporosis: randomized controlled trial.

Fall rates in hospital rehabilitation units after individualised patient and staff education programmes: a pragmatic, stepped-wedge, cluster-randomised controlled trial

Association Between Lifestyle Factors and Mental Health Measures Among Community-Dwelling Older Women

Lower serum testosterone is independently associated with insulin resistance in non-diabetic older men: the Health In Men Study

In men older than 70 years, total testosterone remains stable while free testosterone declines with age. The Health in Men Study

The association of C-reactive protein and CRP genotype with coronary heart disease: findings from five studies with 4,610 cases amongst 18,637 participants

Higher serum undercarboxylated osteocalcin and other bone turnover markers are associated with reduced diabetes risk and lower estradiol concentrations in older men.

Effects of anticholinergic drugs on cognitive function in older Australians: results from the AIBL study

Physical activity and all-cause mortality in older women and men.

Falls, injuries from falls, health related quality of life and mortality in older adults with vision and hearing impairment--is there a gender difference?

Quality use of medicines and health outcomes among a cohort of community dwelling older men: an observational study

150 minutes of vigorous physical activity per week predicts survival and successful ageing: a population-based 11-year longitudinal study of 12 201 older Australian men.

Successful mental health aging: results from a longitudinal study of older Australian men.

24-month effect of smoking cessation on cognitive function and brain structure in later life

Association of Cardiovascular Risk Factors and Disease With Depression in Later Life

Systematic review of the body of evidence for the use of biomarkers in the diagnosis of dementia.

Patterns of dietary intake and psychological distress in older Australians: benefits not just from a Mediterranean diet

Deprescribing in Frail Older People: A Randomised Controlled Trial

Obesity and metabolic syndrome increase the risk of incident depression in older men: the health in men study

B-vitamins reduce the long-term risk of depression after stroke: The VITATOPS-DEP trial

Contribution of the MTHFR gene to the causal pathway for depression, anxiety and cognitive impairment in later life

Anxiety, depression, and comorbid anxiety and depression: risk factors and outcome over two years

Polymorphisms of the CRP gene inhibit inflammatory response and increase susceptibility to depression: the Health in Men Study

Systematic review and meta-analysis of randomized placebo-controlled trials of folate and vitamin B12 for depression

Effectiveness of a smoking cessation intervention in older adults