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List of works by Nicholas H. Heintz

A direct and continuous assay for the determination of thioredoxin reductase activity in cell lysates

scientific article published on 21 August 2013

AMPK activity regulates trafficking of mitochondria to the leading edge during cell migration and matrix invasion

scientific article

Accumulation of E2F-4.DP-1 DNA binding complexes correlates with induction of dhfr gene expression during the G1 to S phase transition

scientific article published on February 1997

Activated cAMP response element binding protein is overexpressed in human mesotheliomas and inhibits apoptosis.

scientific article published on 08 October 2009

Activation of hypoxia-inducible factor-1 protects airway epithelium against oxidant-induced barrier dysfunction ⬇️

scientific article published on September 16, 2011

An amplified chromosomal sequence that includes the gene for dihydrofolate reductase initiates replication within specific restriction fragments

scientific article

An extracellular signal-regulated kinase 1- and 2-dependent program of chromatin trafficking of c-Fos and Fra-1 is required for cyclin D1 expression during cell cycle reentry

scientific article

Asbestos modulates thioredoxin-thioredoxin interacting protein interaction to regulate inflammasome activation

scientific article

Asbestos, lung cancers, and mesotheliomas: from molecular approaches to targeting tumor survival pathways

scientific article

Asbestos-induced lung inflammation and epithelial cell proliferation are altered in myeloperoxidase-null mice

scientific article published in November 2005

Association with E2F-1 governs intracellular trafficking and polyubiquitination of DP-1.

scientific article published on January 1999

Baculovirus P35 inhibits NO-induced apoptosis in activated macrophages by inhibiting cytochrome c release

scientific article published in June 2004

Caspase-dependent apoptosis by ectopic expression of E2F-4

scientific article published on 01 September 2000

Chemical footprinting of structural and functional elements of dhfr oribeta during the CHOC 400 cell cycle

scientific article

Cloning of the initiation region of a mammalian chromosomal replicon.

scientific article

Condensation by DNA looping facilitates transfer of large DNA molecules into mammalian cells

scientific article

Cooperation of E2F-p130 and Sp1-pRb complexes in repression of the Chinese hamster dhfr gene

scientific article published on February 2001

Differential regulation of antioxidant enzymes in response to oxidants

scientific article published on December 1991

Disabling Mitochondrial Peroxide Metabolism via Combinatorial Targeting of Peroxiredoxin 3 as an Effective Therapeutic Approach for Malignant Mesothelioma

scientific article

Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta

scientific article

ERK2 is essential for the growth of human epithelioid malignant mesotheliomas.

scientific article

Evidence that the pre-mRNA splicing factor Clf1p plays a role in DNA replication in Saccharomyces cerevisiae.

scientific article

Functional analysis of bacterial artificial chromosomes in mammalian cells: mouse Cdc6 is associated with the mitotic spindle apparatus

scientific journal article

Gene expression profiles reveal increased mClca3 (Gob5) expression and mucin production in a murine model of asbestos-induced fibrogenesis

scientific article

Human mesothelioma cells exhibit tumor cell-specific differences in phosphatidylinositol 3-kinase/AKT activity that predict the efficacy of Onconase.

scientific article published in May 2005

IDENTIFICATION OF CONOIDIN A AS A COVALENT INHIBITOR OF PEROXIREDOXIN II.

scientific article published on January 2009

Identification of an origin of bidirectional DNA replication in mammalian chromosomes

scientific article published on September 1990

Induction of c-fos and c-jun proto-oncogene expression by asbestos is ameliorated by N-acetyl-L-cysteine in mesothelial cells

scientific article published on May 1995

Induction of c-fos and c-jun proto-oncogenes in target cells of the lung and pleura by carcinogenic fibers.

scientific article published in November 1994

Inhibition of protein kinase C prevents asbestos-induced c-fos and c-jun proto-oncogene expression in mesothelial cells ⬇️

scientific article published on 01 August 1997

Inhibitory effects of novel E2F decoy oligodeoxynucleotides on mesangial cell proliferation by coexpression of E2F/DP.

scientific article

Intramolecular DNA triplexes, bent DNA and DNA unwinding elements in the initiation region of an amplified dihydrofolate reductase replicon

scientific article published on January 1990

Isolation of the origin of replication associated with the amplified Chinese hamster dihydrofolate reductase domain

scientific article published on October 1986

Manipulating genes and gene copy number by bacterial artificial chromosomes transfection

scientific article published on January 2007

Methotrexate-resistant Chinese hamster ovary cells have amplified a 135-kilobase-pair region that includes the dihydrofolate reductase gene.

scientific article

Mitochondrial‐targeted nitroxides disrupt mitochondrial architecture and inhibit expression of peroxiredoxin 3 and FOXM1 in malignant mesothelioma cells ⬇️

scientific article published on April 1, 2013

Modulation of Sp1-dependent transcription by a cis-acting E2F element in dhfr promoter

scientific article

New Insights into Understanding the Mechanisms, Pathogenesis, and Management of Malignant Mesotheliomas ⬇️

scientific article published on February 8, 2013

Nitrogen dioxide enhances allergic airway inflammation and hyperresponsiveness in the mouse

scientific article published on 05 August 2005

Non-specific DNA binding interferes with the efficient excision of oxidative lesions from chromatin by the human DNA glycosylase, NEIL1.

scientific article

Nonphagocytic oxidase 1 causes death in lung epithelial cells via a TNF-RI-JNK signaling axis

scientific article published in November 2006

Nuclear localization of DP and E2F transcription factors by heterodimeric partners and retinoblastoma protein family members

scientific article

Oxidation state governs structural transitions in peroxiredoxin II that correlate with cell cycle arrest and recovery

scientific article

Oxidative processing of latent Fas in the endoplasmic reticulum controls the strength of apoptosis

scientific article

Parameters influencing high-efficiency transfection of bacterial artificial chromosomes into cultured mammalian cells ⬇️

scientific article published on October 1, 2003

Peroxiredoxin 3 Is a Redox-Dependent Target of Thiostrepton in Malignant Mesothelioma Cells ⬇️

scientific article published on June 25, 2012

Peroxiredoxin 3 levels regulate a mitochondrial redox setpoint in malignant mesothelioma cells

scientific article

Peroxiredoxins and Beyond; Redox Systems Regulating Lung Physiology and Disease

scientific article published on 05 April 2019

Persistent induction of c-fos and c-jun expression by asbestos

scientific article

Position and orientation-dependent effects of a eukaryotic Z-triplex DNA motif on episomal DNA replication in COS-7 cells ⬇️

scientific article published on March 15, 1991

Protein-DNA interactions at the major and minor promoters of the divergently transcribed dhfr and rep3 genes during the Chinese hamster ovary cell cycle

scientific article published on February 1996

Purification of RIP60 and RIP100, mammalian proteins with origin-specific DNA-binding and ATP-dependent DNA helicase activities

scientific article

RIP60, a mammalian origin-binding protein, enhances DNA bending near the dihydrofolate reductase origin of replication

scientific article

Reactive nitrogen species block cell cycle re-entry through sustained production of hydrogen peroxide

scientific article published on 10 January 2003

Redox regulation of cell-cycle re-entry: cyclin D1 as a primary target for the mitogenic effects of reactive oxygen and nitrogen species

scientific article published in May 2005

Redox-based regulation of signal transduction: principles, pitfalls, and promises

scientific article published on 27 March 2008

Redox-dependent expression of cyclin D1 and cell proliferation by Nox1 in mouse lung epithelial cells

scientific article published on September 2006

Replication intermediates formed during initiation of DNA synthesis in methotrexate-resistant CHOC 400 cells are enriched for sequences derived from a specific, amplified restriction fragment.

scientific article published in January 1986

Resolution of oxidative stress by thioredoxin reductase: Cysteine versus selenocysteine

scientific article published on 19 February 2014

S-phase arrest by reactive nitrogen species is bypassed by okadaic acid, an inhibitor of protein phosphatases PP1/PP2A.

scientific article published on 14 November 2005

Sequences near the origin of replication of the DHFR locus of Chinese hamster ovary cells adopt left-handed Z-DNA and triplex structures

scientific article published on 01 December 1990

The cell cycle is a redox cycle: linking phase-specific targets to cell fate

scientific article published on 29 May 2009

The dhfr oribeta-binding protein RIP60 contains 15 zinc fingers: DNA binding and looping by the central three fingers and an associated proline-rich region

scientific article

The duration of nuclear extracellular signal-regulated kinase 1 and 2 signaling during cell cycle reentry distinguishes proliferation from apoptosis in response to asbestos

scientific article published in September 2004

The highly conserved tRNAHis guanylyltransferase Thg1p interacts with the origin recognition complex and is required for the G2/M phase transition in the yeast Saccharomyces cerevisiae

scientific article

The replication timing of the amplified dihydrofolate reductase genes in the Chinese hamster ovary cell line CHOC 400.

scientific article published on July 1990

Transcriptional squelching by ectopic expression of E2F-1 and p53 is alleviated by proteasome inhibitors MG-132 and lactacystin ⬇️

scientific article published on August 14, 1997

Transfection of a manganese-containing superoxide dismutase gene into hamster tracheal epithelial cells ameliorates asbestos-mediated cytotoxicity

scientific article

tRNA(His) guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases

scientific article

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