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List of works by David Sugden

5-hydroxytryptophan elevates serum melatonin

scientific article published in August 1983

7-Substituted-melatonin and 7-substituted-1-methylmelatonin analogues: effect of substituents on potency and binding affinity

scientific article published on 10 April 2007

A cholera toxin substrate regulates cyclic GMP content of rat pinealocytes

scientific article published on 01 June 1987

Activation of protein kinase C potentiates isoprenaline-induced cyclic AMP accumulation in rat pinealocytes

scientific article

Acute sleep-promoting action of the melatonin agonist, ramelteon, in the rat.

scientific article published on 19 February 2008

Adrenergic stimulation of rat pineal hydroxyindole-O-methyltransferase

scientific article published on 01 April 1983

Alpha 1-adrenoceptor activation elevates cytosolic calcium in rat pinealocytes by increasing net influx

scientific article published on 01 January 1987

Alpha-adrenergic potentiation of beta-adrenergic stimulation of rat pineal N-acetyltransferase. Studies using cirazoline and fluorine analogs of norepinephrine.

scientific article published on December 1984

An endogenous 5-HT(7) receptor mediates pigment granule dispersion in Xenopus laevis melanophores

scientific article

Analogues of diverse structure are unable to differentiate native melatonin receptors in the chicken retina, sheep pars tuberalis and Xenopus melanophores

scientific article published in September 1996

Atypical synergistic alpha 1- and beta-adrenergic regulation of adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate in rat pinealocytes.

scientific article published in June 1985

Benzocyclobutane, benzocycloheptane and heptene derivatives as melatonin agonists and antagonists

scientific article published on 08 July 2014

Benzodiazepines: rat pinealocyte binding sites and augmentation of norepinephrine-stimulated N-acetyltransferase activity.

scientific article published in February 1984

Beta-adrenergic receptor control of rat pineal hydroxyindole-O-methyltransferase.

scientific article published on July 1983

Bicyclic melatonin receptor agonists containing a ring-junction nitrogen: Synthesis, biological evaluation, and molecular modeling of the putative bioactive conformation

scientific article published on 15 November 2005

Binding affinity and biological activity of oxygen and sulfur isosteres at melatonin receptors as a function of their hydrogen bonding capability

scientific article

Circadian changes in long noncoding RNAs in the pineal gland.

scientific article

Comparison of the structure-activity relationships of melatonin receptor agonists and antagonists: lengthening the N-acyl side-chain has differing effects on potency on Xenopus melanophores

scientific article published on November 1998

Desensitization of pigment granule aggregation in Xenopus leavis melanophores: melatonin degradation rather than receptor down-regulation is responsible

scientific article

Design and synthesis of new N1 and C3-substituted 4-fluoroindolic melatoninergics

scientific article published on October 2007

Design and synthesis of potent N1-substituted indole melatonin receptor agonists

scientific article

Design, synthesis and melatoninergic activity of new unsubstituted and beta,beta'-difunctionalised 2,3-dihydro-1H-pyrrolo[3,2,1-ij]quinolin-6-alkanamides

scientific article published on 21 January 2007

Design, synthesis and melatoninergic potency of new N-acyl 8,9-dihydro-4-methoxy-7H-2-benzo[de]quinolinalkanamines

scientific article published on 9 December 2006

Design, synthesis, and melatoninergic activity of new azido- and isothiocyanato-substituted indoles

scientific article published on 8 November 2007

Development of the rat pineal alpha 1-adrenoceptor

scientific article published in January 1985

FOXM1 upregulation is an early event in human squamous cell carcinoma and it is enhanced by nicotine during malignant transformation

scientific article published in 2009

Global daily dynamics of the pineal transcriptome.

scientific article published on 08 February 2011

Inactivation of rat pineal hydroxyindole-O-methyltransferase by disulfide-containing compounds

scientific article published on 01 May 1987

Mapping the melatonin receptor. 4. Comparison of the binding affinities of a series of substituted phenylalkyl amides

scientific article published on 01 April 1996

Mapping the melatonin receptor. 5. Melatonin agonists and antagonists derived from tetrahydrocyclopent[b]indoles, tetrahydrocarbazoles and hexahydrocyclohept[b]indoles

scientific article published in February 1998

Mapping the melatonin receptor. 7. Subtype selective ligands based on beta-substituted N-acyl-5-methoxytryptamines and beta-substituted N-acyl-5-methoxy-1-methyltryptamines

scientific article published on June 2006

Measurement of tryptophan hydroxylase activity in rat pineal glands and pinealocytes using an HPLC assay with electrochemical detection

scientific article published on 01 January 1989

Melatonin, melatonin receptors and melanophores: a moving story

scientific article

Negative feedback mechanisms: evidence that desensitization of pineal alpha 1-adrenergic responses involves protein kinase-C.

scientific article published in September 1988

Neural adrenergic/cyclic AMP regulation of the immunoglobulin E receptor alpha-subunit expression in the mammalian pinealocyte: a neuroendocrine/immune response link?

scientific article published on 29 August 2007

Night/day changes in pineal expression of >600 genes: central role of adrenergic/cAMP signaling

scientific article

Ovine pineal indoles: effects of L-tryptophan or L-5-hydroxytryptophan administration

scientific article

Pineal function: impact of microarray analysis

scientific article

Postsynaptic alpha-adrenergic receptors potentiate the beta-adrenergic stimulation of pineal serotonin N-acetyltransferase.

scientific article published on January 1983

Purification of rat pineal hydroxyindole-O-methyltransferase using S-adenosyl-L-homocysteine agarose chromatography

scientific article published in January 1986

Rapid nocturnal increase in ovine pineal N-acetyltransferase activity and melatonin synthesis: effects of cycloheximide.

scientific article published in September 1985

Rat pineal alpha 1-adrenoceptor subtypes: studies using radioligand binding and reverse transcription-polymerase chain reaction analysis.

scientific article published in July 1996

Rat pineal alpha 1-adrenoceptors: identification and characterization using [125I]iodo-2-[beta-(4-hydroxyphenyl)-ethylaminomethyl]tetralone

scientific article published on 01 February 1984

Regulation of rat pineal hydroxyindole-O-methyltransferase in neonatal and adult rats.

scientific article published in June 1983

See-saw signal processing in pinealocytes involves reciprocal changes in the alpha 1-adrenergic component of the cyclic GMP response and the beta-adrenergic component of the cyclic AMP response

scientific article

Serum melatonin and pineal indoleamine metabolism in a species with a small day/night N-acetyltransferase rhythm.

scientific article published in January 1985

Synthesis of N1-phenethyl substituted indole derivatives as new melatoninergic agonists and antagonists

scientific article published in January 2002

Thyroid hormone and adrenergic signaling interact to control pineal expression of the dopamine receptor D4 gene (Drd4).

scientific article published on 29 May 2009

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