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List of works by James A. Ferrendelli

3,3-Dialkyl- and 3-alkyl-3-benzyl-substituted 2-pyrrolidinones: a new class of anticonvulsant agents

scientific article published on 01 April 1996

A rat EEG model for evaluating contrast media neurotoxicity

scientific article published in September 1988

Adenosine-mediated regulation of cyclic AMP levels in isolated incubated retinas

scientific article published in February 1986

Alkyl-substituted gamma-butyrolactones act at a distinct site allosterically linked to the TBPS/picrotoxinin site on the GABAA receptor complex

scientific article published in June 1993

Alkyl-substituted thiolo-, thiono-, and dithio-gamma-butyrolactones: new classes of convulsant and anticonvulsant agents

scientific article

Alkyl-substituted γ-butyrolactones as potential tools in the study and treatment of epilepsy

scientific article published on October 15, 1983

Alpha-spirocyclopentyl- and alpha-spirocyclopropyl-gamma-butyrolactones: conformationally constrained derivatives of anticonvulsant and convulsant alpha,alpha-disubstituted gamma-butyrolactones

scientific article published on January 1994

Alpha-substituted gamma-butyrolactones: new class of anticonvulsant drugs

scientific article published on 01 September 1982

Anterior thalamus and substantia nigra: two distinct structures mediating experimental generalized seizures

scientific article published in November 1986

Anticonvulsant properties of alpha, gamma, and alpha, gamma-substituted gamma-butyrolactones.

scientific article published in September 1982

Binding interactions of convulsant and anticonvulsant gamma-butyrolactones and gamma-thiobutyrolactones with the picrotoxin receptor

scientific article published on August 1990

Characterization of GABAergic seizure regulation in the midline thalamus

scientific article published in July 1990

Comparison of epileptogenic properties of unsubstituted and beta-alkyl-substituted gamma-butyrolactones

scientific article published in September 1982

Comparison of the anticonvulsant activities of ethosuximide, valproate, and a new anticonvulsant, thiobutyrolactone

scientific article (publication date: 1989)

Comparison of the effects of biogenic amines on cyclic GMP and cyclic AMP levels in mouse cerebellumin vitro

scientific article published on January 24, 1975

Comparison of the effects of depolarizing agents and neurotransmitters on regional CNS cyclic GMP levels in various animals

scientific article published on March 1, 1976

Computer-assisted modeling of the picrotoxinin and gamma-butyrolactone receptor site

scientific article published on March 1, 1983

Convulsant and anti-convulsant gammabutyrolactones bind at the picrotoxinin/T-butylbicyclophosphorothionate (TBPS) receptor

scientific article published on 01 December 1985

Convulsant and anticonvulsant cyclopentanones and cyclohexanones

scientific article published on 01 January 1990

Cyclic Nucleotides in Epileptic Brain: Effects of Pentylenetetrazol on Regional Cyclic AMP and Cyclic GMP Levels In Vivo

scientific article published on December 1, 1977

Developmental alteration in GABAA receptor structure and physiological properties in cultured cerebellar granule neurons

scientific article published in July 1994

Distribution and regulation of cyclic nucleotide levels in cerebellum, in vivo

scientific article published on July 1, 1977

Dual modulation of the gamma-aminobutyric acid type A receptor/ionophore by alkyl-substituted gamma-butyrolactones

scientific article published on June 1, 1995

Effects of alkyl-substituted gamma-butyrolactones and succinimides on the evoked and spontaneous activity of hippocampal slices in vitro

scientific article published in December 1983

Effects of amphetamine, chlorpromazine and reserpine on cyclic GMP and cyclic AMP levels in mouse cerebellum

scientific article published in March 1972

Effects of anticonvulsant and convulsant gamma-butyrolactones and thiobutyrolactones on GABA-mediated chloride uptake

scientific article published on March 1987

Effects of reserpine, propranolol, and aminophylline on seizure activity and CNS cyclic nucleotides

scientific article published on October 1, 1979

Electroencephalographic effects of intracisternally injected nonionic x-ray contrast media in rats.

scientific article published in September 1990

Elevation of cyclic GMP levels in central nervous system by excitatory and inhibitory amino acids

scientific article published in April 1974

Enantioselectivity of alpha-benzyl-alpha-methyl-gamma-butyrolactone-mediated modulation of anticonvulsant activity and GABA(A) receptor function

scientific article published on 23 January 2004

Eyelid twitching seizures and generalized tonic-clonic convulsions: a syndrome of idiopathic generalized epilepsy

scientific article published on 01 March 1990

Functional anatomy of pentylenetetrazol and electroshock seizures in the rat brainstem

scientific article

Gamma-butyrolactone antagonism of the picrotoxin receptor: comparison of a pure antagonist and a mixed antagonist/inverse agonist

scientific article published on 01 January 1991

Identification of a median thalamic system regulating seizures and arousal

scientific article published in July 1989

Influence of divalent cations on regulation of cyclic GMP and cyclic AMP levels in brain tissue

scientific article published on April 1, 1976

Inhibitory effects of anticonvulsant drugs on cyclic nucleotide accumulation in brain

scientific article (publication date: June 1979)

Lactone Modulation of the γ-Aminobutyric Acid A Receptor: Evidence for a Positive Modulatory Site

scientific article published on 01 July 1997

Levels of cerebral cortical glycolytic and citric acid cycle metabolites during hypoglycemic stupor and its reversal

scientific article published on August 1, 1977

Measurement of cyclic nucleotides in histologically defined samples of brain and retina

scientific article published on March 1, 1977

Phenytoin: Effects on Calcium Flux and Cyclic Nucleotides

scientific article published on September 1, 1977

Physiological comparison of alpha-ethyl-alpha-methyl-gamma-thiobutyrolactone with benzodiazepine and barbiturate modulators of GABAA receptors

scientific article published in February 1996

Physiological modulation of the GABA receptor by convulsant and anticonvulsant barbiturates in cultured rat hippocampal neurons

scientific article published in May 1990

Physiological regulation of the picrotoxin receptor by gamma-butyrolactones and gamma-thiobutyrolactones in cultured hippocampal neurons.

scientific article published in June 1990

Quick freezing of the murine CNS: comparison of regional cooling rates and metabolite levels when using liquid nitrogen of Freon-12.

scientific article published in April 1972

Regional levels of glucose, amino acids, high energy phosphates, and cyclic nucleotides in the central nervous system during hypoglycemic stupor and behavioral recovery

scientific article published in November 1976

Regulation of levels of guanosine cyclic 3',5'-monophosphate in the central nervous system: effects of depolarizing agents

scientific article published in July 1973

Relative anticonvulsant effects of GABAmimetic and GABA modulatory agents

scientific article published on November 1, 1992

Similar effects of phenytoin and tetrodotoxin on cyclic nucleotid regulation in depolarized brain tissue

scientific article published on December 1, 1978

Structure-activity relationships of alkyl-substituted gamma-butyrolactones and succinimides.

scientific article

Structure-activity studies of fluoroaljyl-substituted γ-butyrolactone and γ-thiobutyrolactone modulators of GABAA receptor function

scientific article published on January 1, 1998

Synthesis and anticonvulsant activities of 3,3-dialkyl- and 3-alkyl-3-benzyl-2-piperidinones (delta-valerolactams) and hexahydro-2H-azepin-2-ones (epsilon-caprolactams)

scientific article published on 01 January 1997

Synthesis and structure-activity studies of alkyl-substituted .gamma.-butyrolactones and .gamma.-thiobutyrolactones: ligands for the picrotoxin receptor

scientific article published on April 1, 1991

The KEEPER trial: levetiracetam adjunctive treatment of partial-onset seizures in an open-label community-based study

scientific article published on May 2003

The central medial nucleus: thalamic site of seizure regulation

scientific article

The effect of oxotremorine and atropine on cGMP and cAMP levels in mouse cerebral cortex and cerebellum

scientific article published in November 1970

Use of levetiracetam in a population of patients aged 65 years and older: a subset analysis of the KEEPER trial

scientific article published on December 2003

Voltage-dependent calcium channels as targets for convulsant and anticonvulsant alkyl-substituted thiobutyrolactones

scientific article published on 01 February 1997

What you see is not what you get: believing patient-reported seizure counts

scientific article published on 01 November 2007