List of works - Matt J Petrus

A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition.

scientific article published on 17 December 2007

An ion channel essential for sensing chemical damage.

scientific article

Discovery, optimization, and biological evaluation of 5-(2-(trifluoromethyl)phenyl)indazoles as a novel class of transient receptor potential A1 (TRPA1) antagonists.

scientific article

GPR68 Senses Flow and Is Essential for Vascular Physiology.

scientific article published in April 2018

High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol

scientific article

Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype

scientific article published on 15 November 2011

Impaired thermosensation in mice lacking TRPV3, a heat and camphor sensor in the skin.

scientific article

Nociceptive signals induce trafficking of TRPA1 to the plasma membrane

scientific article

Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin

scientific article (publication date: 25 March 2004)

Opposite thermosensor in fruitfly and mouse.

scientific article published in June 2003

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels ⬇️

scientific article published on September 2, 2010

Piezo2 is required for Merkel-cell mechanotransduction

scientific journal article

Piezo2 is the major transducer of mechanical forces for touch sensation in mice

scientific article

Pore region of TRPV3 ion channel is specifically required for heat activation

scientific article published in September 2008

TRPA1 contributes to cold hypersensitivity

scientific journal article

TRPM8 is required for cold sensation in mice

scientific journal article

TRPV1 and TRPA1 mediate peripheral nitric oxide-induced nociception in mice

scientific article

TRPV1 is activated by both acidic and basic pH.

scientific article

TRPV3 regulates nitric oxide synthase-independent nitric oxide synthesis in the skin

scientific article

Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain

scientific article published on 22 April 2010

Two amino acid residues determine 2-APB sensitivity of the ion channels TRPV3 and TRPV4

scholarly article

Zinc activates damage-sensing TRPA1 ion channels

scientific article

List of works by Matt J Petrus

A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition.

An ion channel essential for sensing chemical damage.

Discovery, optimization, and biological evaluation of 5-(2-(trifluoromethyl)phenyl)indazoles as a novel class of transient receptor potential A1 (TRPA1) antagonists.

GPR68 Senses Flow and Is Essential for Vascular Physiology.

High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol

Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype

Impaired thermosensation in mice lacking TRPV3, a heat and camphor sensor in the skin.

Nociceptive signals induce trafficking of TRPA1 to the plasma membrane

Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin

Opposite thermosensor in fruitfly and mouse.

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels ⬇️

Piezo2 is required for Merkel-cell mechanotransduction

Piezo2 is the major transducer of mechanical forces for touch sensation in mice

Pore region of TRPV3 ion channel is specifically required for heat activation

TRPA1 contributes to cold hypersensitivity

TRPM8 is required for cold sensation in mice

TRPV1 and TRPA1 mediate peripheral nitric oxide-induced nociception in mice

TRPV1 is activated by both acidic and basic pH.

TRPV3 regulates nitric oxide synthase-independent nitric oxide synthesis in the skin

Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain

Two amino acid residues determine 2-APB sensitivity of the ion channels TRPV3 and TRPV4

Zinc activates damage-sensing TRPA1 ion channels