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List of works by Regina Heidenreich

A New RNA-Based Adjuvant Enhances Virus-Specific Vaccine Responses by Locally Triggering TLR- and RLH-Dependent Effects

scientific article published on 11 January 2017

A novel RNA-based adjuvant combines strong immunostimulatory capacities with a favorable safety profile

scientific article published on 8 January 2015

A novel, disruptive vaccination technology: self-adjuvanted RNActive(®) vaccines

scientific article published on 04 June 2013

Abscopal effects of radiotherapy and combined mRNA-based immunotherapy in a syngeneic, OVA-expressing thymoma mouse model.

scientific article published on 16 January 2018

Angiogenesis drives psoriasis pathogenesis

scientific article published on June 2009

Angiogenesis: the new potential target for the therapy of psoriasis?

scientific article published on March 2008

Cooperative interaction of hypoxia-inducible factor-2alpha (HIF-2alpha ) and Ets-1 in the transcriptional activation of vascular endothelial growth factor receptor-2 (Flk-1)

scientific journal article

Design, synthesis, and biological evaluation of novel 3-aryl-4-(1H-indole-3yl)-1,5-dihydro-2H-pyrrole-2-ones as vascular endothelial growth factor receptor (VEGF-R) inhibitors

scientific article

EpCAM, a human tumor-associated antigen promotes Th2 development and tumor immune evasion

scientific article

Highly potent mRNA based cancer vaccines represent an attractive platform for combination therapies supporting an improved therapeutic effect ⬇️

scientific article published on June 1, 2012

Immunological effects of a novel RNA-based adjuvant in liver cancer patients

scientific article published on 10 November 2016

Inhibition of solid tumor growth by gene transfer of VEGF receptor-1 mutants

scientific article published on September 2004

Local gene transfer of phVEGF-2 plasmid by gene-eluting stents: an alternative strategy for inhibition of restenosis

scientific article published on 21 June 2004

Microtumor growth initiates angiogenic sprouting with simultaneous expression of VEGF, VEGF receptor-2, and angiopoietin-2.

scientific article

Phase Ib study evaluating a self-adjuvanted mRNA cancer vaccine (RNActive®) combined with local radiation as consolidation and maintenance treatment for patients with stage IV non-small cell lung cancer

scientific article

RNA-based adjuvant CV8102 enhances the immunogenicity of a licensed rabies vaccine in a first-in-human trial

scientific article published on 21 February 2019

RNActive® Technology: Generation and Testing of Stable and Immunogenic mRNA Vaccines

scientific article published on 01 January 2017

RNAdjuvant®, a novel, highly-potent RNA-based adjuvant, combines strong immunostimulatory capacities with a favorable safety profile

scientific article published on 4 November 2015

Self-adjuvanted RNActive® vaccine induces local immune responses at the injection site leading to potent adaptive immunity in mice and humans

article

Self-adjuvanted RNActive® vaccines provide a promising platform for combination therapies with checkpoint inhibitors.

scientific article published on 6 November 2014

Self-adjuvanted mRNA vaccines induce local innate immune responses that lead to a potent and boostable adaptive immunity

scientific article

Signaling mechanism of extracellular RNA in endothelial cells

scientific article

Simultaneous blockade of VEGFR-1 and VEGFR-2 activation is necessary to efficiently inhibit experimental melanoma growth and metastasis formation

scientific article published on 01 May 2007

Tracking adult neovascularization during ischemia and inflammation using Vegfr2-LacZ reporter mice.

scientific article

Unmodified mRNA in LNPs constitutes a competitive technology for prophylactic vaccines

scientific article published on 19 October 2017

mRNA Cancer Vaccines

scientific article published on January 2016

mRNA mediates passive vaccination against infectious agents, toxins, and tumors.

scientific article published on 9 August 2017

mRNA-based vaccines synergize with radiation therapy to eradicate established tumors

scientific article published on 15 August 2014

mRNA: A Novel Avenue to Antibody Therapy?

scientific article published on 06 March 2019

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