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List of works by Kris Thielemans

Activation of Immature Monocyte-Derived Dendritic Cells After Transduction with High Doses of Lentiviral Vectors

scientific article published on 01 June 2007

Activation of monocytes via the CD14 receptor leads to the enhanced lentiviral transduction of immature dendritic cells

scientific article published in June 2004

Adjuvant-Enhanced mRNA Vaccines

scientific article

Attenuated Expression of A20 Markedly Increases the Efficacy of Double-Stranded RNA-Activated Dendritic Cells As an Anti-Cancer Vaccine

scientific article published on 01 January 2009

CD83 expression on dendritic cells and T cells: correlation with effective immune responses

scientific article published on March 2007

Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety

scientific article published on 01 October 2018

Dendritic cells differentiated in the presence of IFN-β and IL-3 are potent inducers of an antigen-specific CD8+ T cell response

scientific article published on 21 July 2005

Design of an Optimized Wilms' Tumor 1 (WT1) mRNA Construct for Enhanced WT1 Expression and Improved Immunogenicity In Vitro and In Vivo

scientific article

Expression of human GITRL on myeloid dendritic cells enhances their immunostimulatory function but does not abrogate the suppressive effect of CD4+CD25+ regulatory T cells

scientific article

Functional T-cell responses generated by dendritic cells expressing the early HIV-1 proteins Tat, Rev and Nef.

scientific article

Generation of large numbers of dendritic cells in a closed system using Cell Factories.

scientific article published on June 2002

Identification of new antigenic peptide presented by HLA-Cw7 and encoded by several MAGE genes using dendritic cells transduced with lentiviruses

scientific article published on February 2004

Immunogenicity of targeted lentivectors.

scientific article published on February 2014

Intralymphatic mRNA vaccine induces CD8 T-cell responses that inhibit the growth of mucosally located tumours

scientific article published on 2 March 2016

Intratumoral Delivery of TriMix mRNA Results in T-cell Activation by Cross-Presenting Dendritic Cells.

scientific article published on 11 December 2015

Intratumoral administration of mRNA encoding a fusokine consisting of IFN-β and the ectodomain of the TGF-β receptor II potentiates antitumor immunity

scientific article

Intratumoral delivery of mRNA: Overcoming obstacles for effective immunotherapy

scientific article published on 3 February 2015

Lentiviral vectors for anti-tumor immunotherapy.

scientific article published on December 2008

Lentivirally transduced dendritic cells as a tool for cancer immunotherapy

scientific article published on 01 August 2003

Messenger RNA-electroporated dendritic cells presenting MAGE-A3 simultaneously in HLA class I and class II molecules.

scientific article published on June 2004

Modulation of regulatory T cell function by monocyte-derived dendritic cells matured through electroporation with mRNA encoding CD40 ligand, constitutively active TLR4, and CD70.

scientific article published on 10 July 2013

Neo-Antigen mRNA Vaccines

scientific article published on 18 December 2020

Optimized dendritic cell-based immunotherapy for melanoma: the TriMix-formula

scientific article

Particle-mediated Intravenous Delivery of Antigen mRNA Results in Strong Antigen-specific T-cell Responses Despite the Induction of Type I Interferon

scientific article published on 21 June 2016

Preclinical Evaluation of TriMix and Antigen mRNA-Based Antitumor Therapy

scientific article published on 15 February 2012

Proinflammatory characteristics of SMAC/DIABLO-induced cell death in antitumor therapy.

scientific article

Side-by-side comparison of lentivirally transduced and mRNA-electroporated dendritic cells: implications for cancer immunotherapy protocols.

scientific article published on October 2004

Targeting of human antigen-presenting cell subsets.

scientific article published on 17 July 2013

Targeting the tumor microenvironment to enhance antitumor immune responses

scientific article

The ReNAissanCe of mRNA-based cancer therapy

scientific article published on 29 September 2014

The potential of antigen and TriMix sonoporation using mRNA-loaded microbubbles for ultrasound-triggered cancer immunotherapy

scientific article published on 22 August 2014

The role of SMAC mimetics in regulation of tumor cell death and immunity

scientific article published on September 2012

The transduction pattern of IL-12-encoding lentiviral vectors shapes the immunological outcome

scientific article published on 17 September 2015

Variegation and silencing in a lentiviral-based murine transgenic model

scientific article

mRNA-based dendritic cell vaccines.

scientific article published on 08 September 2014

mRNA: From a chemical blueprint for protein production to an off-the-shelf therapeutic.

scientific article published on 04 January 2013

mRNA: delivering an antitumor message?

scientific article published on 01 May 2011