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List of works by Danila Valmori

A monoclonal melanoma-specific T-cell population phenotypically indistinguishable from CD3+ LGL-leukemia

scientific article published on 01 June 2003

A peripheral circulating compartment of natural naive CD4 Tregs

scientific article

A phenotype based approach for the immune monitoring of NY-ESO-1-specific CD4+ T cell responses in cancer patients.

scientific article

Activation of human melanoma reactive CD8+ T cells by vaccination with an immunogenic peptide analog derived from Melan-A/melanoma antigen recognized by T cells-1

scientific article published on 01 February 2003

An immunodominant SSX-2-derived epitope recognized by CD4+ T cells in association with HLA-DR.

scientific article published on April 2004

Antibody responses to NY-ESO-1 in primary breast cancer identify a subtype target for immunotherapy.

scientific article

Antigenicity and immunogenicity of Melan-A/MART-1 derived peptides as targets for tumor reactive CTL in human melanoma.

scientific article

Application of support vector machines for T-cell epitopes prediction

scientific article

Assessment of CD4+ T cells specific for the tumor antigen SSX-1 in cancer-free individuals.

scientific article published on 22 December 2006

Assessment of MAGE-A expression in resected non-small cell lung cancer in relation to clinicopathologic features and mutational status of EGFR and KRAS

scientific article published on 27 May 2014

Assessment of vaccine-induced CD4 T cell responses to the 119-143 immunodominant region of the tumor-specific antigen NY-ESO-1 using DRB1*0101 tetramers

scientific article published on 29 July 2010

CD28-negative cytolytic effector T cells frequently express NK receptors and are present at variable proportions in circulating lymphocytes from healthy donors and melanoma patients

scientific article published in June 1999

CD4(+) T helper cell responses to NY-ESO-1 tumor antigen in ovarian cancer resist perversion into immunosuppressive Tregs.

scientific article

CD4+ T effectors specific for the tumor antigen NY-ESO-1 are highly enriched at ovarian cancer sites and coexist with, but are distinct from, tumor-associated Treg

scientific article published on 19 August 2013

CXCR3+ T regulatory cells selectively accumulate in human ovarian carcinomas to limit type I immunity.

scientific article

Circulating Tumor-reactive CD8(+) T cells in melanoma patients contain a CD45RA(+)CCR7(-) effector subset exerting ex vivo tumor-specific cytolytic activity

scientific article published on 01 March 2002

Combinatorial peptide library-based identification of peptide ligands for tumor-reactive cytolytic T lymphocytes of unknown specificity

scientific article

Comment on "differentiation of IL-17-producing effector and regulatory human T cells from lineage-committed naive precursors"

scientific article published on 01 October 2014

Comment on "helios+ and helios- cells coexist within the natural FOXP3+ T regulatory cell subset in humans".

scientific article published in May 2013

Consensus nomenclature for CD8(+) T cell phenotypes in cancer

scientific article published on 25 February 2015

Correction: Immune Responses to the Cancer Testis Antigen XAGE-1b in Non Small Cell Lung Cancer Caucasian Patients

scientific article published on 28 July 2016

Cross-presentation of HLA class I epitopes from exogenous NY-ESO-1 polypeptides by nonprofessional APCs

scientific article published on 01 February 2003

Cross-presentation of NY-ESO-1 cytotoxic T lymphocyte epitope fused to human heat shock cognate protein 70 by dendritic cells

scientific article published on 7 November 2007

Decreased Binding of Peptides-MHC Class I (pMHC) Multimeric Complexes to CD8 Affects Their Binding Avidity for the TCR But Does Not Significantly Impact on pMHC/TCR Dissociation Rate ⬇️

scientific article published on May 15, 2003

Degeneracy of antigen recognition as the molecular basis for the high frequency of naive A2/Melan-a peptide multimer(+) CD8(+) T cells in humans

scientific article

Differential expression of CCR7 defines two distinct subsets of human memory CD4+CD25+ Tregs

scientific article published on 31 December 2007

Differential expression of the immunosuppressive enzyme IL4I1 in human induced Aiolos+, but not natural Helios+, FOXP3+ Treg cells

scientific article published on 16 January 2015

Differential presentation of a soluble exogenous tumor antigen, NY-ESO-1, by distinct human dendritic cell populations

scientific article

Dissecting TCR-MHC/peptide complex interactions with A2/peptide multimers incorporating tumor antigen peptide variants: crucial role of interaction kinetics on functional outcomes

scientific article published on 01 November 2002

Distinct structural TCR repertoires in naturally occurring versus vaccine-induced CD8+ T-cell responses to the tumor-specific antigen NY-ESO-1

scientific article published on 01 May 2005

Efficacy of levo-1-methyl tryptophan and dextro-1-methyl tryptophan in reversing indoleamine-2,3-dioxygenase-mediated arrest of T-cell proliferation in human epithelial ovarian cancer

scientific article

Epitope clustering in regions undergoing efficient proteasomal processing defines immunodominant CTL regions of a tumor antigen

scientific article published on 24 October 2006

Ex vivo IL-1 receptor type I expression in human CD4+ T cells identifies an early intermediate in the differentiation of Th17 from FOXP3+ naive regulatory T cells.

scientific article published on 12 October 2011

Ex-vivo analysis of CD8+ T cells infiltrating colorectal tumors identifies a major effector-memory subset with low perforin content.

scientific article published on 12 September 2006

Expression of MAGE-A3/6 in primary breast cancer is associated with hormone receptor negative status, high histologic grade, and poor survival.

scientific article

Expression of synovial sarcoma X (SSX) antigens in epithelial ovarian cancer and identification of SSX-4 epitopes recognized by CD4+ T cells

scientific article

Final antigenic Melan-A peptides produced directly by the proteasomes are preferentially selected for presentation by HLA-A*0201 in melanoma cells

scientific article

Findings on T cell specificity revealed by synthetic combinatorial libraries

scientific article

Functional analysis of HLA-A*0201/Melan-A peptide multimer+ CD8+ T cells isolated from an HLA-A*0201- donor: exploring tumor antigen allorestricted recognition

scientific article published on July 12, 2002

Functional avidity of tumor antigen-specific CTL recognition directly correlates with the stability of MHC/peptide multimer binding to TCR

scientific article published on 01 February 2002

Generation of Th17 from human naive CD4+ T cells preferentially occurs from FOXP3+ Tregs upon costimulation via CD28 or CD5.

scientific article published in May 2012

HLA class I - associated immunodominance affects CTL responsiveness to an ESO recombinant protein tumor antigen vaccine

scientific article published on 01 January 2009

Human RORγt+ TH17 cells preferentially differentiate from naive FOXP3+Treg in the presence of lineage-specific polarizing factors

scientific article

Human T(H)17 immune cells specific for the tumor antigen MAGE-A3 convert to IFN-γ-secreting cells as they differentiate into effector T cells in vivo.

scientific article published on 17 January 2012

Human memory FOXP3+ Tregs secrete IL-17 ex vivo and constitutively express the T(H)17 lineage-specific transcription factor RORgamma t. ⬇️

scholarly article

Human memory Helios- FOXP3+ regulatory T cells (Tregs) encompass induced Tregs that express Aiolos and respond to IL-1β by downregulating their suppressor functions

scientific article published on 25 September 2013

IFN-gamma enables cross-presentation of exogenous protein antigen in human Langerhans cells by potentiating maturation

scholarly article

IL-1beta and IL-2 convert human Treg into T(H)17 cells

scientific article published on 11 February 2009

Identification of B cell epitopes recognized by antibodies specific for the tumor antigen NY-ESO-1 in cancer patients with spontaneous immune responses.

scientific article published in October 2005

Identification of an SSX-2 epitope presented by dendritic cells to circulating autologous CD4+ T cells.

scientific article published in June 2004

Identification of two Melan-A CD4+ T cell epitopes presented by frequently expressed MHC class II alleles

scientific article

Immune Responses to the Cancer Testis Antigen XAGE-1b in Non Small Cell Lung Cancer Caucasian Patients

scientific article

Interleukin 2-mediated conversion of ovarian cancer-associated CD4+ regulatory T cells into proinflammatory interleukin 17-producing helper T cells.

scientific article published in February 2009

Lentivector immunization induces tumor antigen-specific B and T cell responses in vivo

scientific article published on 01 July 2008

MHC class II/ESO tetramer-based generation of in vitro primed anti-tumor T-helper lines for adoptive cell therapy of cancer.

scientific article published on 8 August 2012

Melan-A/MART-1-specific CD8 T cells: from thymus to tumor

scientific article

Modulation of Cytokine Secretion Allows CD4 T Cells Secreting IL-10 and IL-17 to Simultaneously Participate in Maintaining Tolerance and Immunity

scientific article published on 28 December 2015

Monitoring of NY-ESO-1 specific CD4+ T cells using molecularly defined MHC class II/His-tag-peptide tetramers.

scientific article

Multiepitope CD8(+) T cell response to a NY-ESO-1 peptide vaccine results in imprecise tumor targeting

scientific article

NY-ESO-1-specific circulating CD4+ T cells in ovarian cancer patients are prevalently T(H)1 type cells undetectable in the CD25+ FOXP3+ Treg compartment.

scientific article

Positional scanning-synthetic peptide library-based analysis of self- and pathogen-derived peptide cross-reactivity with tumor-reactive Melan-A-specific CTL.

scientific article

Prevalent role of TCR alpha-chain in the selection of the preimmune repertoire specific for a human tumor-associated self-antigen.

scientific article

Processing of tumor-associated antigen by the proteasomes of dendritic cells controls in vivo T-cell responses.

scientific article published in May 2006

Prospective strategies to combine conventional, targeted and immunotherapies in non-small cell lung cancer.

scientific article published on 29 October 2014

Quantitative and qualitative assessment of circulating NY-ESO-1 specific CD4+ T cells in cancer-free individuals.

scientific article published on 15 August 2005

Rapamycin-mediated enrichment of T cells with regulatory activity in stimulated CD4+ T cell cultures is not due to the selective expansion of naturally occurring regulatory T cells but to the induction of regulatory functions in conventional CD4+ T

scientific article published on 01 July 2006

Recombinant vaccinia/fowlpox NY-ESO-1 vaccines induce both humoral and cellular NY-ESO-1-specific immune responses in cancer patients.

scholarly article

Regulation of CD4(+)NKG2D(+) Th1 cells in patients with metastatic melanoma treated with sorafenib: role of IL-15Rα and NKG2D triggering

scientific article published on 6 November 2013

SSX antigens as tumor vaccine targets in human sarcoma

scientific article published on 09 October 2003

Simultaneous CD8+ T cell responses to multiple tumor antigen epitopes in a multipeptide melanoma vaccine

scientific article published on October 28, 2003

The frequent expression of cancer/testis antigens provides opportunities for immunotherapeutic targeting of sarcoma.

scientific article published on 9 August 2004

Therapeutic cancer vaccines based on molecularly defined human tumor antigens

scientific article published on 01 December 2002

Thymic selection generates a large T cell pool recognizing a self-peptide in humans

scientific article

Tinkering with nature: the tale of optimizing peptide based cancer vaccines.

scientific article

Tissue homing and persistence of defined antigen-specific CD8+ tumor-reactive T-cell clones in long-term melanoma survivors

scientific article published on 12 October 2006

Tumor-reactive, SSX-2-specific CD8+ T cells are selectively expanded during immune responses to antigen-expressing tumors in melanoma patients ⬇️

scientific article published on September 1, 2003

Vaccination with NY-ESO-1 protein and CpG in Montanide induces integrated antibody/Th1 responses and CD8 T cells through cross-priming.

scholarly article

Vaccination with a Melan-A peptide selects an oligoclonal T cell population with increased functional avidity and tumor reactivity

scientific article published on 01 April 2002

Vaccination with a recombinant protein encoding the tumor-specific antigen NY-ESO-1 elicits an A2/157-165-specific CTL repertoire structurally distinct and of reduced tumor reactivity than that elicited by spontaneous immune responses to NY-ESO-1-ex

scientific article

Vaccination with recombinant NY-ESO-1 protein elicits immunodominant HLA-DR52b-restricted CD4+ T cell responses with a conserved T cell receptor repertoire

scientific article published on 16 June 2009

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