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List of works by Sacha Gnjatic

A COMMON PITUITARY AUTOANTIBODY IN TWO PATIENTS WITH IMMUNE CHECKPOINT INHIBITOR-MEDIATED HYPOPHYSITIS: ZCCHC8

scientific article published on 03 April 2020

A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GM-CSF.

scientific article published on July 2016

A Phase 1b Study Evaluating the Safety, Tolerability, and Immunogenicity of CMB305, a Lentiviral-Based Prime-Boost Vaccine Regimen, in Patients with Locally Advanced, Relapsed, or Metastatic Cancer Expressing NY-ESO-1

scientific article published on 19 November 2020

A Pilot Study of Anti-CTLA4 Antibody Ipilimumab in Patients with Synovial Sarcoma.

scientific article published on 27 February 2013

A Streamlined CyTOF Workflow To Facilitate Standardized Multi-Site Immune Profiling of COVID-19 Patients

scientific article published on 29 June 2020

A case of spontaneous systemic immunity to melanoma associated with cure after amputation for extensive regional recurrence

scientific article

A multimodal imaging workflow to visualize metal mixtures in the human placenta and explore colocalization with biological response markers

scientific article

A novel human-derived antibody against NY-ESO-1 improves the efficacy of chemotherapy

scientific article (publication date: 2013)

A tertiary center experience of multiple myeloma patients with COVID-19: lessons learned and the path forward

scientific article published on 05 June 2020

A tertiary center experience of multiple myeloma patients with COVID-19: lessons learned and the path forward

scientific article published on 14 July 2020

Antibody-targeted NY-ESO-1 to mannose receptor or DEC-205 in vitro elicits dual human CD8+ and CD4+ T cell responses with broad antigen specificity

scientific article published on 13 December 2010

Antigen depots: T cell traps? ⬇️

scientific article published on 01 April 2013

Autoantibodies against cancer antigens

scientific article published in January 2009

Autologous Lymphocyte Infusion Supports Tumor Antigen Vaccine-Induced Immunity in Autologous Stem Cell Transplant for Multiple Myeloma

scientific article published on 11 February 2019

Booster vaccination of cancer patients with MAGE-A3 protein reveals long-term immunological memory or tolerance depending on priming

scholarly article

CD4+ CD25+ regulatory T cells control the induction of antigen-specific CD4+ helper T cell responses in cancer patients

scientific article published on 19 April 2005

CD8 tumor-infiltrating lymphocytes are predictive of survival in muscle-invasive urothelial carcinoma

scholarly article

CD8(+) T cell responses against a dominant cryptic HLA-A2 epitope after NY-ESO-1 peptide immunization of cancer patients

scientific article

CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit

scholarly article

CTdatabase: a knowledge-base of high-throughput and curated data on cancer-testis antigens

scientific article

Cancer classification using the Immunoscore: a worldwide task force

scientific article

Cancer-testis antigen 7 expression and immune responses following allogeneic stem cell transplantation for multiple myeloma

scientific article published on 3 March 2014

Cancer-testis antigens and immunosurveillance in human cutaneous squamous cell and basal cell carcinomas.

scientific article published on 2 June 2010

Cancer-testis antigens are commonly expressed in multiple myeloma and induce systemic immunity following allogeneic stem cell transplantation

scientific article

Cancer-testis genes are coordinately expressed and are markers of poor outcome in non-small cell lung cancer

scientific article

Cancer/testis antigen expression and autologous humoral immunity to NY-ESO-1 in gastric cancer

scientific article published on 01 November 2004

Cancer/testis antigens are novel targets of immunotherapy for adult T-cell leukemia/lymphoma

scientific article published on 8 February 2012

Cancer/testis antigens expression and autologous serological response in a set of Brazilian non-Hodgkin's lymphoma patients.

scientific article published on 26 May 2012

Cellular immune responses against CT7 (MAGE-C1) and humoral responses against other cancer-testis antigens in multiple myeloma patients.

scientific article

Characterization of preexisting MAGE-A3-specific CD4+ T cells in cancer patients and healthy individuals and their activation by protein vaccination

scientific article

Chemoradiotherapy-induced upregulation of PD-1 antagonizes immunity to HPV-related oropharyngeal cancer

scientific article published on 15 October 2014

Clinical trial of the intratumoral administration of labeled DC combined with systemic chemotherapy for esophageal cancer

scientific article published on 01 July 2012

Clonality and antigen-specific responses shape the prognostic effects of tumor-infiltrating T cells in ovarian cancer

scientific article published on 07 July 2020

Consensus nomenclature for CD8(+) T cell phenotypes in cancer

scientific article published on 25 February 2015

Correction: NY-ESO-1 Cancer Testis Antigen Demonstrates High Immunogenicity in Triple Negative Breast Cancer

Correlation of clinical and immunological data in a metastatic melanoma patient with heterogeneous tumor responses to ipilimumab therapy

scientific article

Covid-19 and People with HIV Infection: Outcomes for Hospitalized Patients in New York City

scientific article published on 28 June 2020

Cross-presentation of HLA class I epitopes from exogenous NY-ESO-1 polypeptides by nonprofessional APCs

scientific article published on 01 February 2003

Cytotoxic lymphocytes are dysregulated in multisystem inflammatory syndrome in children

scientific article published on 02 September 2020

Differential presentation of a soluble exogenous tumor antigen, NY-ESO-1, by distinct human dendritic cell populations

scientific article

Direct tumor recognition by a human CD4(+) T-cell subset potently mediates tumor growth inhibition and orchestrates anti-tumor immune responses

scientific article

Dissecting cytotoxic T cell responses towards the NY-ESO-1 protein by peptide/MHC-specific antibody fragments

scientific article published on October 2004

Effect of Montanide and poly-ICLC adjuvant on human self/tumor antigen-specific CD4+ T cells in phase I overlapping long peptide vaccine trial

scientific article

Efficacy of vaccination with recombinant vaccinia and fowlpox vectors expressing NY-ESO-1 antigen in ovarian cancer and melanoma patients

scientific article published on 27 March 2012

Enhancement of tumor-reactive cytotoxic CD4+ T cell responses after ipilimumab treatment in four advanced melanoma patients

scientific article published on October 2013

Epigenetic potentiation of NY-ESO-1 vaccine therapy in human ovarian cancer

scientific article published on January 2014

Erratum: Correlationof clinical and immunological data in a metastatic melanoma patient with heterogeneous tumor responses to ipilimumab therapy.

scientific article

Evaluation of LAGE-1 and NY-ESO-1 expression in multiple myeloma patients to explore possible benefits of their homology for immunotherapy

scientific article

Ex-vivo analysis of CD8+ T cells infiltrating colorectal tumors identifies a major effector-memory subset with low perforin content.

scientific article published on 12 September 2006

Expansion and Activation of CD103(+) Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition.

scientific article published on April 2016

Expression and clinical significance of MAGE and NY-ESO-1 cancer-testis antigens in adenoid cystic carcinoma of the head and neck

scientific article

Expression and immune responses to MAGE antigens predict survival in epithelial ovarian cancer

scientific article

Expression of cancer testis antigen CT45 in classical Hodgkin lymphoma and other B-cell lymphomas

scientific article

Expression of synovial sarcoma X (SSX) antigens in epithelial ovarian cancer and identification of SSX-4 epitopes recognized by CD4+ T cells

scientific article

First-in-Human Treatment With a Dendritic Cell-targeting Lentiviral Vector-expressing NY-ESO-1, LV305, Induces Deep, Durable Response in Refractory Metastatic Synovial Sarcoma Patient.

scientific article published in October 2017

First-in-human phase 1 dose-escalating trial of G305 in patients with advanced solid tumors expressing NY-ESO-1

scientific article published on 08 May 2019

Frequency of NY-ESO-1 and LAGE-1 expression in bladder cancer and evidence of a new NY-ESO-1 T-cell epitope in a patient with bladder cancer

scientific article published on 18 December 2003

Future perspectives in melanoma research. Meeting report from the "Melanoma Bridge. Napoli, December 2nd-4th 2012".

scientific article published on 3 June 2013

Genetic engineering of T cells with receptors from NY-ESO-1-specific tumor-recognizing CD4+ T cell as a novel approach for adoptive T cell therapy

scientific article published on 4 November 2015

HLA superfamily assignment is a predictor of immune response to cancer testis antigens and survival in ovarian cancer

scientific article

HLA-DP4 expression and immunity to NY-ESO-1: correlation and characterization of cytotoxic CD4+ CD25- CD8- T cell clones.

scientific article

Heat shock protein 90-mediated peptide-selective presentation of cytosolic tumor antigen for direct recognition of tumors by CD4(+) T cells

scientific article

Heteroclitic serological response in esophageal and prostate cancer patients after NY-ESO-1 protein vaccination

scientific article

Host tissue determinants of tumour immunity

scientific article published on 01 April 2019

IFN-gamma enables cross-presentation of exogenous protein antigen in human Langerhans cells by potentiating maturation

scholarly article

IMMU-60. MAPPING TUMORAL AND IMMUNE HETEROGENEITY IN PD-1 RESPONSIVE GLIOBLASTOMA

Identification of a naturally processed NY-ESO-1 peptide recognized by CD8+ T cells in the context of HLA-B51.

scientific article published on 19 September 2002

Identification of new NY-ESO-1 epitopes recognized by CD4+ T cells and presented by HLA-DQ B1 03011.

scientific article published on February 2006

Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer.

scientific article published on 8 November 2017

Identifying baseline immune-related biomarkers to predict clinical outcome of immunotherapy

scientific article

Immune biomarkers are more accurate in prediction of survival in ulcerated than in non-ulcerated primary melanomas

scientific article

Immune responses detected in urothelial carcinoma patients after vaccination with NY-ESO-1 protein plus BCG and GM-CSF

scientific article published on 01 November 2008

Immunization of malignant melanoma patients with full-length NY-ESO-1 protein using TLR7 agonist imiquimod as vaccine adjuvant

scientific article published on July 2008

Immunization with a recombinant MAGE-A3 protein after high-dose therapy for myeloma

scientific article published on 01 November 2007

Immunohistochemical Detection of γ/δ T Lymphocytes in Formalin-fixed Paraffin-embedded Tissues

scientific article published on 01 September 2019

Immunologic correlates of the abscopal effect in a patient with melanoma

scientific article (publication date: 8 March 2012)

Impact of chemotherapy alone, and chemotherapy plus ipilimumab, on circulating immune cells in patients with metastatic bladder cancer

scientific article published on 4 November 2015

In vitro stimulation of CD8 and CD4 T cells by dendritic cells loaded with a complex of cholesterol-bearing hydrophobized pullulan and NY-ESO-1 protein: Identification of a new HLA-DR15-binding CD4 T-cell epitope.

scientific article published on March 2006

In vivo antigen delivery by a Salmonella typhimurium type III secretion system for therapeutic cancer vaccines.

scientific article

In-depth tissue profiling using multiplexed immunohistochemical consecutive staining on single slide

scientific article

Inducing efficient cross-priming using antigen-coated yeast particles

scientific article published on September 2008

Induction of regulatory T cell-resistant helper CD4+ T cells by bacterial vector.

scientific article published on 6 November 2007

Influence of CD4+CD25+ regulatory T cells on low/high-avidity CD4+ T cells following peptide vaccination

scientific article published in May 2006

Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses.

scientific article published in May 2017

Integrated NY-ESO-1 antibody and CD8+ T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab

scientific article

Intracellular tumor-associated antigens represent effective targets for passive immunotherapy.

scientific article published on 8 February 2012

Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer

scientific article

Intratumoral checkpoint subversion as a strategy for minimizing adverse effects: Harvesting the power of TILs without harvesting TILs

scientific article published on 3 January 2014

Ipilimumab for patients with advanced mucosal melanoma

scientific article

Ipilimumab increases activated T cells and enhances humoral immunity in patients with advanced melanoma

scientific article published in January 2012

LUD 00-009: phase 1 study of intensive course immunization with NY-ESO-1 peptides in HLA-A2 positive patients with NY-ESO-1-expressing cancer.

scientific article

Localization and density of immune cells in the invasive margin of human colorectal cancer liver metastases are prognostic for response to chemotherapy

scientific article published on 16 August 2011

Long-term complete remission following radiosurgery and immunotherapy in a melanoma patient with brain metastasis: immunologic correlates

scientific article published on 5 February 2014

MAGE expression in head and neck squamous cell carcinoma primary tumors, lymph node metastases and respective recurrences-implications for immunotherapy.

scientific article published on 27 January 2017

MAGE-A3 is highly expressed in a subset of colorectal cancer patients

scientific article published on 28 December 2012

MRI radiomics features predict immuno-oncological characteristics of hepatocellular carcinoma

scientific article published on 21 February 2020

Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C)

preprint published on 06 July 2020

Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C)

scientific article published on 14 September 2020

Melanoma and immunotherapy bridge 2015 : Naples, Italy. 1-5 December 2015

scientific article

Monitoring CD4+ T cell responses against viral and tumor antigens using T cells as novel target APC.

scientific article published in July 2003

Multiepitope CD8(+) T cell response to a NY-ESO-1 peptide vaccine results in imprecise tumor targeting

scientific article

Multiplexed Immunohistochemical Consecutive Staining on Single Slide (MICSSS): Multiplexed Chromogenic IHC Assay for High-Dimensional Tissue Analysis

scientific article published on 01 January 2020

NY-CO-58/KIF2C is overexpressed in a variety of solid tumors and induces frequent T cell responses in patients with colorectal cancer

scientific article

NY-ESO-1 DNA vaccine induces T-cell responses that are suppressed by regulatory T cells

scientific article published on 10 March 2009

NY-ESO-1 and LAGE-1 cancer-testis antigens are potential targets for immunotherapy in epithelial ovarian cancer.

scientific article published in September 2003

NY-ESO-1 cancer testis antigen demonstrates high immunogenicity in triple negative breast cancer

scientific article

NY-ESO-1 expression and immunogenicity in esophageal cancer

scientific article published in October 2004

NY-ESO-1 expression and immunogenicity in malignant and benign breast tumors

scientific article published in March 2004

NY-ESO-1 expression predicts an aggressive phenotype of ovarian cancer

scientific article published on 6 April 2017

NY-ESO-1 mRNA expression and immunogenicity in advanced prostate cancer

scientific article

NY-ESO-1 specific antibody and cellular responses in melanoma patients primed with NY-ESO-1 protein in ISCOMATRIX and boosted with recombinant NY-ESO-1 fowlpox virus

scientific article published on 14 August 2014

NY-ESO-1: review of an immunogenic tumor antigen

scientific article

Nonclassical antigen-processing pathways are required for MHC class II-restricted direct tumor recognition by NY-ESO-1-specific CD4(+) T cells

scientific article published on 17 December 2013

Overcoming regulatory T-cell suppression by a lyophilized preparation of Streptococcus pyogenes

scientific article published on 26 February 2013

PLAC1, a trophoblast-specific cell surface protein, is expressed in a range of human tumors and elicits spontaneous antibody responses

scientific article

Pathophysiology of SARS-CoV-2: targeting of endothelial cells renders a complex disease with thrombotic microangiopathy and aberrant immune response. The Mount Sinai COVID-19 autopsy experience

scientific article published on 22 May 2020

Perspectives in immunotherapy: meeting report from the “Immunotherapy Bridge”, Napoli, December 5th 2015.

scientific article published on 18 October 2016

Phase 2 Trial of Gemcitabine, Cisplatin, plus Ipilimumab in Patients with Metastatic Urothelial Cancer and Impact of DNA Damage Response Gene Mutations on Outcomes

scientific article published on 13 December 2017

Phase I clinical trial of mixed bacterial vaccine (Coley's toxins) in patients with NY-ESO-1 expressing cancers: immunological effects and clinical activity

scientific article published on 30 July 2012

Phase I/II study of Resiquimod as an immunologic adjuvant for NY-ESO-1 protein vaccination in patients with melanoma

scientific article published on 7 November 2013

Physical interaction of two cancer-testis antigens, MAGE-C1 (CT7) and NY-ESO-1 (CT6)

scientific article

Presence of B Cells in Tertiary Lymphoid Structures Is Associated with a Protective Immunity in Patients with Lung Cancer

scientific article published on 01 April 2014

Prognostic value of immune cells in the tumor microenvironment of early-stage lung cancer: a meta-analysis

scientific article published on 24 December 2019

Prostate cancer progression correlates with increased humoral immune response to a human endogenous retrovirus GAG protein

scientific article published on 30 September 2013

Protein Expression Analysis of Melanocyte Differentiation Antigen TRP-2.

scientific article published on March 2016

RHAMM-R3 peptide vaccination in patients with acute myeloid leukemia, myelodysplastic syndrome, and multiple myeloma elicits immunologic and clinical responses

scientific article published on 31 October 2007

Radiotherapy induces responses of lung cancer to CTLA-4 blockade

Recognition of naturally processed and ovarian cancer reactive CD8+ T cell epitopes within a promiscuous HLA class II T-helper region of NY-ESO-1.

scientific article published on 6 February 2008

Recombinant NY-ESO-1 protein with ISCOMATRIX adjuvant induces broad integrated antibody and CD4+ and CD8+ T cell responses in humans

scholarly article

Recombinant vaccinia/fowlpox NY-ESO-1 vaccines induce both humoral and cellular NY-ESO-1-specific immune responses in cancer patients.

scholarly article

Regulatory T cell-resistant CD8+ T cells induced by glucocorticoid-induced tumor necrosis factor receptor signaling.

scientific article published in July 2008

Safety and immunogenicity study of NY-ESO-1b peptide and montanide ISA-51 vaccination of patients with epithelial ovarian cancer in high-risk first remission.

scientific article published in May 2008

Seromic analysis of antibody responses in non-small cell lung cancer patients and healthy donors using conformational protein arrays.

scientific article

Seromic profiling of ovarian and pancreatic cancer

scientific article

Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy

scientific article published on 29 August 2019

Split T cell tolerance against a self/tumor antigen: spontaneous CD4+ but not CD8+ T cell responses against p53 in cancer patients and healthy donors

scientific article

Split T-cell tolerance as a guide for the development of tumor antigen-specific immunotherapy

scientific article published on May 2012

Survey of naturally occurring CD4+ T cell responses against NY-ESO-1 in cancer patients: correlation with antibody responses

scientific article

Tertiary Lymphoid Structure-Associated B Cells are Key Players in Anti-Tumor Immunity

scientific article

Th1/Th2 CD4+ T cell responses against NY-ESO-1 in HLA-DPB1*0401/0402 patients with epithelial ovarian cancer

scientific article published on 3 November 2004

The Society for Immunotherapy in Cancer statement on best practices for multiplex immunohistochemistry (IHC) and immunofluorescence (IF) staining and validation

scientific article published on 01 May 2020

The abscopal effect associated with a systemic anti-melanoma immune response

scientific article

The non-small cell lung cancer immune contexture. A major determinant of tumor characteristics and patient outcome

scientific article

The spontaneous CD8+ T-cell response to HLA-A2-restricted NY-ESO-1b peptide in hepatocellular carcinoma patients

scientific article published in October 2004

Therapeutic administration of a synthetic CpG oligodeoxynucleotide triggers formation of anti-CpG antibodies

scientific article

Trypanosoma cruzi as an effective cancer antigen delivery vector.

scientific article published on 23 November 2011

Tumor-infiltrating NY-ESO-1-specific CD8+ T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer

scientific article

Tumor-infiltrating T lymphocyte clonality predicts prognosis in human ovarian cancer

scientific article published on 7 November 2013

Tumor-reactive CD8+ T-cell clones in patients after NY-ESO-1 peptide vaccination

scientific article

Tumor-reactive CD8+ T-cell responses after vaccination with NY-ESO-1 peptide, CpG 7909 and Montanide ISA-51: association with survival

scientific article

Tumoral and immune heterogeneity in an anti-PD-1-responsive glioblastoma: a case study

scientific article published on 01 April 2020

Urine antibody against human cancer antigen NY-ESO-1

scientific article published on 06 August 2002

Vaccination with an NY-ESO-1 peptide of HLA class I/II specificities induces integrated humoral and T cell responses in ovarian cancer

scholarly article

Vaccine-induced CD4+ T cell responses to MAGE-3 protein in lung cancer patients

scientific article published in March 2004

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