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Authors whose works are in public domain in at least one jurisdiction

List of works by Robert J. Lutz

A Potent Cell Death Activity Associated with Transient High Level Expression of BCL-2 ⬇️

scientific article published on July 10, 1998

A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions

scientific article

A cytomegalovirus-encoded mitochondria-localized inhibitor of apoptosis structurally unrelated to Bcl-2.

scientific article published on October 1999

A flow system for the study of shear forces upon cultured endothelial cells

scientific article

A model for the kinetics of distribution of actinomycin-D in the beagle dog ⬇️

scientific article published on 01 March 1977

A novel anti-CD37 antibody-drug conjugate with multiple anti-tumor mechanisms for the treatment of B-cell malignancies ⬇️

scientific article published on September 3, 2013

A preliminary pharmacokinetic model for several chlorinated biphenyls in the rat ⬇️

scientific article published on July 1, 1977

A review of the applications of physiologically based pharmacokinetic modeling

scientific article published on April 1979

Alphav integrin-targeted immunoconjugates regress established human tumors in xenograft models

scientific article

Anin VitroFlow Model to Study Streaming during Pelvic Intra-arterial Drug Infusions ⬇️

scientific article published on 01 November 1995

Antibody-maytansinoid conjugates are activated in targeted cancer cells by lysosomal degradation and linker-dependent intracellular processing

scientific article

Antibody-maytansinoid conjugates designed to bypass multidrug resistance

scientific article

Antibody-maytansinoid conjugates for the treatment of myeloma

scientific article

Bak BH3 peptides antagonize Bcl-xL function and induce apoptosis through cytochrome c-independent activation of caspases

scientific article published on 01 May 1999

Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria

scientific article

Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins

scientific article

Comparison of steady and pulsatile flow in a double branching arterial model

scientific article published on January 1983

Comparison of the pharmacokinetics of several polychlorinated biphenyls in mouse, rat, dog, and monkey by means of a physiological pharmacokinetic model ⬇️

scientific article published on 01 September 1984

Defective elongation of fatty acids in a recessive 25-hydroxycholesterol-resistant mutant cell line.

scientific article published on August 1990

Design of Coltuximab Ravtansine, a CD19-Targeting Antibody-Drug Conjugate (ADC) for the Treatment of B-Cell Malignancies: Structure-Activity Relationships and Preclinical Evaluation

scientific article

Different analogues of farnesyl pyrophosphate inhibit squalene synthase and protein:farnesyltransferase to different extents

scientific article published on March 1995

Disulfide-Linked Antibody−Maytansinoid Conjugates: Optimization of In Vivo Activity by Varying the Steric Hindrance at Carbon Atoms Adjacent to the Disulfide Linkage ⬇️

scientific article published on March 22, 2011

Drug streaming during intra-arterial chemotherapy

scientific article published on February 1986

Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals

scientific article

Feedback inhibition of polyisoprenyl pyrophosphate synthesis from mevalonate in vitro. Implications for protein prenylation ⬇️

scientific article published on April 25, 1992

Glioblastoma: catheter techniques for isolated chemotherapy perfusion

scientific article published in May 1986

Growth factors inactivate the cell death promoter BAD by phosphorylation of its BH3 domain on Ser155.

scientific article

Hepatic artery model for evaluating the distribution of intraarterial chemotherapy infusion: nonpulsed versus pulsed infusions

scientific article published on 01 March 1989

IMGN853, a Folate Receptor-α (FRα)-Targeting Antibody-Drug Conjugate, Exhibits Potent Targeted Antitumor Activity against FRα-Expressing Tumors

scientific article published on 22 April 2015

Implications of pharmacokinetic modeling in risk assessment analysis

scientific article

In Vivo Methotrexate Transport in Murine Lewis Lung Tumor ⬇️

scientific article published on August 1, 1979

In vitro study of simultaneous infusion of incompatible drugs in multilumen catheters

scientific article published on 01 May 1991

Induction of apoptosis by the Bcl-2 homologue Bak

scientific article

Injection characteristics and downstream contrast material distribution of flush aortography catheters: in vitro study

scientific article published on November 1, 1992

Lorvotuzumab mertansine, a CD56-targeting antibody-drug conjugate with potent antitumor activity against small cell lung cancer in human xenograft models

scientific article published on 08 January 2014

Maytansinoid immunoconjugate IMGN901 is cytotoxic in a three-dimensional culture model of multiple myeloma

scientific article published on 18 May 2016

Mixing studies during intracarotid artery infusions in an in vitro model

scientific article published on February 1986

Pharmacokinetic study of cis-dichlorodiammineplatinum(II) (DDP) in the beagle dog: thermodynamic and kinetic behavior of DDP in a biologic millieu

scientific article published on January 1, 1979

Physiological pharmacokinetics: an in vivo approach to membrane transport

scientific article published on January 1980

Purification of a phospholipase C from rat liver cytosol that acts on phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 4-phosphate

scientific article published in November 1988

Quantification and pharmacokinetics of blood-brain barrier disruption in humans

scientific article published on December 1996

Ras (CXXX) and Rab (CC/CXC) prenylation signal sequences are unique and functionally distinct ⬇️

scientific article published on December 5, 1992

Relative toxicity of methotrexate in several tissues of mice bearing Lewis lung carcinoma ⬇️

scientific article published on June 1, 1974

Semisynthetic maytansine analogues for the targeted treatment of cancer

scientific article published on July 2006

Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate

scientific article

The construction of a pharmacokinetic model for the disposition of polychlorinated biphenyls in the rat ⬇️

scientific article published on November 1, 1977

The prenylation of proteins

scientific article published on January 1, 1992

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