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List of works by Frans P. Nijkamp

A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation

scientific article published on 12 February 2006

ATP and the pathogenesis of COPD.

scientific article

ATP in the pathogenesis of lung emphysema

scientific article published on 3 August 2009

Acetylsalicylic acid-induced release of HSP70 from mast cells results in cell activation through TLR pathway

scientific article (publication date: 2006)

Acute allergic skin response as a new tool to evaluate the allergenicity of whey hydrolysates in a mouse model of orally induced cow's milk allergy.

scientific article published on 26 June 2009

Airway nitrergic pathways: is there therapeutic potential in asthma and COPD?

scientific article published on 01 June 2004

Alveolar macrophages have a dual role in a rat model for trimellitic anhydride-induced occupational asthma

scientific article published in July 2005

Alveolar macrophages suppress non-specific inflammation caused by inhalation challenge with trimellitic anhydride conjugated to albumin

scientific article published on 17 February 2006

Antigen Binding Characteristics of Immunoglobulin Free Light Chains: Crosslinking by Antigen is Essential to Induce Allergic Inflammation ⬇️

scientific article published on July 20, 2012

Aspirin induces the production of the inflammatory mediator 8-epi-PGF in mast cells

scientific article (publication date: 14 August 2006)

Beneficial effect of tachykinin NK1 receptor antagonism in the development of hapten-induced colitis in mice

scientific article published on 25 July 2006

Ca2+ sensors modulate asthmatic symptoms in an allergic model for asthma

scientific article published in August 2003

Capsazepine, a vanilloid receptor antagonist, inhibits allergen-induced tracheal contraction.

scientific article published in July 2005

Cells, mediators and Toll-like receptors in COPD.

scientific article published on 18 March 2008

Characterization of a phosphorylated peptide and peptoid and peptoid-peptide hybrids by mass spectrometry.

scientific article published on January 2002

Chlamydophila pneumoniae induces a sustained airway hyperresponsiveness and inflammation in mice

scientific article

Cigarette smoke attenuates the production of cytokines by human plasmacytoid dendritic cells and enhances the release of IL-8 in response to TLR-9 stimulation

scientific article published on 10 June 2009

Cigarette smoke regulates the expression of TLR4 and IL-8 production by human macrophages.

scientific article published on May 2009

Cigarette smoke stimulates the production of chemokines in mast cells

scientific article published on 21 December 2007

Cigarette smoke-induced lung emphysema in mice is associated with prolyl endopeptidase, an enzyme involved in collagen breakdown.

scientific article

Combination of fluticasone propionate and salmeterol potentiates the suppression of cigarette smoke-induced IL-8 production by macrophages

scientific article published on 05 June 2007

Critical role for mast cells in the pathogenesis of 2,4-dinitrobenzene-induced murine colonic hypersensitivity reaction

scientific article published on 01 April 2006

Differential responsiveness of proximal and distal parts of isolated guinea pig trachea

scientific article

Dual effects of acetylsalicylic acid on mast cell degranulation, expression of cyclooxygenase-2 and release of pro-inflammatory cytokines

scientific article (publication date: April 2005)

Editorial

scientific article published in December 2013

Effect of cigarette smoke extract on dendritic cells and their impact on T-cell proliferation.

scientific article

Elicitation of allergic asthma by immunoglobulin free light chains

scientific article

Eotaxin protein levels and airway pathology in a mouse model for allergic asthma

scientific article published on 01 October 2002

Free immunoglobulin light chains: a novel target in the therapy of inflammatory diseases

scientific article published on 18 March 2008

Functional expression of neurokinin 1 receptors on mast cells induced by IL-4 and stem cell factor

scientific article published in August 2003

Genetic analysis of antigen-induced airway manifestations of asthma using recombinant congenic mouse strains

scientific article published on 01 March 2002

Glutathione and other low-molecular-weight thiols relax guinea pig trachea ex vivo: interactions with nitric oxide?

scientific article

Hapten-induced hypersensitivity reactions in the airways: atopic versus non-atopic

scientific article published on July 2002

Humic acid enhances cigarette smoke-induced lung emphysema in mice and IL-8 release of human monocytes

scientific article published on 24 July 2011

IL-8 production by macrophages is synergistically enhanced when cigarette smoke is combined with TNF-alpha

scientific article published on 27 October 2009

Identification of novel target proteins in Th2-dominated allergic inflammatory responses using complementary DNA representational difference analysis and complementary DNA microarrays

scholarly article

Ig-free light chains play a crucial role in murine mast cell-dependent colitis and are associated with human inflammatory bowel diseases

scientific article published on 26 May 2010

Immunoglobulin free light chains and mast cells: pivotal role in T-cell-mediated immune reactions? ⬇️

scientific article published on April 1, 2003

Immunoglobulin-free light chains elicit immediate hypersensitivity-like responses

scientific article published on 17 June 2002

Immunoglobulin-free light chains mediate antigen-specific responses of murine dorsal root ganglion neurons.

scientific article published on 15 February 2009

Immunomodulatory effects of antigen-pulsed macrophages in a murine model of allergic asthma

scientific article published in August 2002

Increased expression and decreased activity of cytochrome P450 1A1 in a murine model of toluene diisocyanate-induced asthma

scientific article published on 21 August 2002

Induction of HSP70 is dispensable for anti-inflammatory action of heat shock or NSAIDs in mast cells

scientific article (publication date: April 2006)

Induction of lung emphysema is prevented by L-arginine-threonine-arginine

scientific article published on 12 June 2008

Inflammatory changes in the airways of mice caused by cigarette smoke exposure are only partially reversed after smoking cessation

scientific article

Influence of the macrophage bacterial resistance gene, Nramp1 (Slc11a1), on the induction of allergic asthma in the mouse

scientific article published on 28 March 2003

Key role for mast cells in nonatopic asthma

scientific article published in August 2002

Lung proteome alterations in a mouse model for nonallergic asthma.

scientific article

Mast cell activation is differentially affected by heat shock

scientific article published in August 2005

Mast cell-derived TNF-alpha primes sensory nerve endings in a pulmonary hypersensitivity reaction

scientific article

Mast cells and nerves tickle in the tummy: implications for inflammatory bowel disease and irritable bowel syndrome

scientific article published on 18 July 2007

Mechanisms of allergy and asthma

scientific article published on 18 March 2008

Murine model for non-IgE-mediated asthma

scientific article published in June 2004

Mycobacteria, genes and the 'hygiene hypothesis'.

scientific article published on February 2004

N-acetylated Proline-Glycine-Proline induced G-protein dependent chemotaxis of neutrophils is independent of CXCL8 release

scientific article published on 31 March 2011

Neuro-immune interactions in inflammatory bowel disease and irritable bowel syndrome: future therapeutic targets

scientific article published on 18 March 2008

New endogenous CXC chemokine ligands as potential targets in lung emphysema

scientific article published on 18 March 2008

New insights on the possible role of mast cells in aspirin-induced asthma

scientific article published on June 2009

Nitric oxide in asthma therapy

scientific article published on January 2006

Nitric oxide synthase (NOS) as therapeutic target for asthma and chronic obstructive pulmonary disease

scientific article published on June 2006

Open letter to the European Commission: scientifically unfounded precaution drives European Commission's recommendations on EDC regulation, while defying common sense, well-established science, and risk assessment principles

scientific article published on 27 August 2013

Overexpression of endothelial nitric oxide synthase suppresses features of allergic asthma in mice

scientific article

Pulmonary intravascular volume can be used for dose calculation in isolated lung perfusion

scientific article published in October 2005

Ramp-ing up allergies: Nramp1 (Slc11a1), macrophages and the hygiene hypothesis.

scientific article published on July 2004

Respiratory sensitization: advances in assessing the risk of respiratory inflammation and irritation.

scientific article published on 05 May 2011

Salmeterol with fluticasone enhances the suppression of IL-8 release and increases the translocation of glucocorticoid receptor by human neutrophils stimulated with cigarette smoke.

scientific article published on 4 July 2008

Scientifically unfounded precaution drives European Commission's recommendations on EDC regulation, while defying common sense, well-established science and risk assessment principles.

scientific article published on 5 July 2013

Scientifically unfounded precaution drives European Commission's recommendations on EDC regulation, while defying common sense, well-established science and risk assessment principles.

scientific article published in December 2013

Scientifically unfounded precaution drives European Commission's recommendations on EDC regulation, while defying common sense, well-established science and risk assessment principles.

scientific article

Scientifically unfounded precaution drives European Commission’s recommendations on EDC regulation, while defying common sense, well-established science and risk assessment principles

scientific article published in September 2013

Scientifically unfounded precaution drives European Commission’s recommendations on EDC regulation, while defying common sense, well-established science and risk assessment principles

scientific article published in October 2013

Specific modulation of calmodulin activity induces a dramatic production of superoxide by alveolar macrophages

scientific article published in January 2004

Stimulation of cysteinyl leukotriene production in mast cells by heat shock and acetylsalicylic acid

scientific article (publication date: 30 April 2007)

Substance P can stimulate prostaglandin D2 and leukotriene C4 generation without granule exocytosis in murine mast cells

scientific article published in April 2004

Subunits of IgM reconstitute defective contact sensitivity in B-1 cell-deficient xid mice: kappa light chains recruit T cells independent of complement

scientific article published in October 2002

TNF-alpha is crucial for the development of mast cell-dependent colitis in mice

scientific article published on 22 June 2006

The Slc11a1 (Nramp1) gene controls efficacy of mycobacterial treatment of allergic asthma.

scientific article published on July 2003

The guinea pig as an animal model for asthma.

scientific article published on June 2008

The tachykinin NK1 receptor is crucial for the development of non-atopic airway inflammation and hyperresponsiveness

scientific article published in August 2003

Therapeutic treatment with heat-killed Mycobacterium vaccae (SRL172) in a mild and severe mouse model for allergic asthma

scientific article published on 01 June 2003

Toll-like receptor-4 mediates cigarette smoke-induced cytokine production by human macrophages.

scientific article published on 19 April 2006

Trimellitic anhydride-conjugated serum albumin activates rat alveolar macrophages in vitro

scientific article

TrkAd5: A novel therapeutic agent for treatment of inflammatory pain and asthma.

scientific article published on 11 November 2005

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