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List of works by Joyce B J van Meurs

25-Hydroxyvitamin D and osteoarthritis: A meta-analysis including new data

scientific article

A Peripheral Blood DNA Methylation Signature of Hepatic Fat Reveals a Potential Causal Pathway for Nonalcoholic Fatty Liver Disease

scientific article published on 01 April 2019

A characterization of cis- and trans-heritability of RNA-Seq-based gene expression

scientific article published on 26 September 2019

A functional polymorphism in the catechol-O-methyltransferase gene is associated with osteoarthritis-related pain

scientific article published on 01 February 2009

A genetic variant in the seed region of miR-4513 shows pleiotropic effects on lipid and glucose homeostasis, blood pressure, and coronary artery disease

scientific article published in December 2014

A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22

scientific journal article

A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation

scientific article

A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus.

scientific article published on 16 December 2013

A meta-analysis of gene expression signatures of blood pressure and hypertension

scientific article (publication date: March 2015)

A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip

scientific article

A systematic analysis highlights multiple long non-coding RNAs associated with cardiometabolic disorders.

scientific article published on 30 January 2018

A variant in MCF2L is associated with osteoarthritis

scientific article

A whole-blood transcriptome meta-analysis identifies gene expression signatures of cigarette smoking

scientific article

Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms

scientific article published on 22 September 2016

An Epigenome-Wide Association Study (EWAS) of Obesity-Related Traits

An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits

scientific article

An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis.

scientific article published on 13 June 2019

Annotating transcriptional effects of genetic variants in disease relevant tissue: Transcriptome-wide allelic imbalance in osteoarthritic cartilage

scientific article published on 23 February 2019

Are Bone Mineral Density and Fractures Related to the Incidence and Progression of Radiographic Osteoarthritis of the Knee, Hip, and Hand in Elderly Men and Women? The Rotterdam Study

scientific article published on 09 February 2019

Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies

scientific article

Association between biomarkers of tissue inflammation and progression of osteoarthritis: evidence from the Rotterdam study cohort

scientific article published on April 2016

Association of 5' estrogen receptor alpha gene polymorphisms with bone mineral density, vertebral bone area and fracture risk

scientific article

Association of Methylation Signals With Incident Coronary Heart Disease in an Epigenome-Wide Assessment of Circulating Tumor Necrosis Factor α.

scientific article

Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals

scientific article published on 01 August 2019

Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults

Associations between joint effusion in the knee and gene expression levels in the circulation: a meta-analysis.

scientific article published on 27 January 2016

Associations between medication use and homocysteine levels in an older population, and potential mediation by vitamin B12 and folate: data from the B-PROOF Study

scientific article

Associations of polymorphisms of eight muscle- or metabolism-related genes with performance in Mount Olympus marathon runners

scientific article published on 31 December 2009

Asymptomatic radiographic hip osteoarthritis is associated with gait differences, especially in women: A population-based study

scientific article published on 16 March 2017

Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation

scientific article published in Nature Communications

B-vitamin levels and genetics of hyperhomocysteinemia are not associated with arterial stiffness

article

Biomarkers for osteoarthritis: Can they be used for risk assessment? A systematic review.

scientific article

Blood RNA expression profiles undergo major changes during the seventh decade

scientific article published on 17 September 2016

Blood lipids influence DNA methylation in circulating cells

scientific article published on 27 June 2016

Bone parameters across different types of hip osteoarthritis and their relationship to osteoporotic fracture risk

scientific article published in March 2013

COPD GWAS variant at 19q13.2 in relation with DNA methylation and gene expression

scientific article

Caenorhabditis elegans orthologs of human genes differentially expressed with age are enriched for determinants of longevity

scientific article published on 12 April 2017

Cam Deformity and Acetabular Dysplasia as Risk Factors for Hip Osteoarthritis

scientific article published on October 2016

Cdx-2 polymorphism in the promoter region of the human vitamin D receptor gene determines susceptibility to fracture in the elderly

scientific article published in September 2003

Cell Specific eQTL Analysis without Sorting Cells

scientific article published on 8 May 2015

Cell type specific DNA methylation in cord blood: A 450K-reference data set and cell count-based validation of estimated cell type composition

scientific article

Chronic joint pain in the lower body is associated with gait differences independent from radiographic osteoarthritis

scientific article

Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture

scientific article

Common Genetic Determinants of Vitamin D Insufficiency: A Genome-Wide Association Study

Common genetic determinants of vitamin D insufficiency: a genome-wide association study

scientific article

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease

scientific article

Common genetic variation in the Estrogen Receptor Beta (ESR2) gene and osteoarthritis: results of a meta-analysis

scientific article

Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking

scientific article published on 19 September 2019

DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation

scientific article published on 30 November 2017

DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies

article published in 2018

DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis

scientific article published on 30 March 2016

DNA methylation mediates the effect of maternal smoking during pregnancy on birthweight of the offspring

scientific article

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

scientific article published on 12 December 2016

DNA methylation signatures of educational attainment

scientific article published on 23 March 2018

DNA methylation-based measures of biological age: meta-analysis predicting time to death

scientific article

Degenerative inter-vertebral disc disease osteochondrosis intervertebralis in Europe: prevalence, geographic variation and radiological correlates in men and women aged 50 and over

scientific article published on 7 April 2017

Determinants for Quantitative Sensory Testing and the Association with Chronic Musculoskeletal Pain in the General Elderly Population

scientific article published on 23 July 2015

Differential Genetic Effects of ESR1 Gene Polymorphisms on Osteoporosis Outcomes

scientific article published in The Journal of the American Medical Association

Differentially methylated regions in T cells identify kidney transplant patients at risk for de novo skin cancer.

scientific article

Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure

scientific article

Disease variants alter transcription factor levels and methylation of their binding sites

scientific article published on 5 December 2016

Dissecting the association of autophagy-related genes with cardiovascular diseases and intermediate vascular traits: A population-based approach

article

Diversity, compositional and functional differences between gut microbiota of children and adults

scientific article published on 23 January 2020

Effect of Vitamin B12 and Folic Acid Supplementation on Bone Mineral Density and Quantitative Ultrasound Parameters in Older People with an Elevated Plasma Homocysteine Level: B-PROOF, a Randomized Controlled Trial

scientific article published on 25 February 2015

Effect of daily vitamin B-12 and folic acid supplementation on fracture incidence in elderly individuals with an elevated plasma homocysteine concentration: B-PROOF, a randomized controlled trial

scientific article published in October 2014

Effect of dietary B vitamins on BMD and risk of fracture in elderly men and women: the Rotterdam study

scientific article published on 17 August 2007

Effect of genetic variants associated with plasma homocysteine levels on stroke risk

scientific article

Epigenetic Link Between Statin Therapy and Type 2 Diabetes

scientific article published on 07 February 2020

Epigenetic Signatures of Cigarette Smoking

scientific article

Epigenome-wide Association Study Identifies Methylation Sites Associated With Liver Enzymes and Hepatic Steatosis

scientific article published on 14 June 2017

Epigenome-wide association study (EWAS) on lipids: the Rotterdam Study

scientific article published on 07 February 2017

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

scientific article published on 21 December 2016

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article published in November 2011

Estrogen receptor alpha gene polymorphisms and risk of myocardial infarction

scientific article published in June 2004

Estrogen receptor alpha gene polymorphisms are associated with estradiol levels in postmenopausal women

scientific article published in August 2005

Estrogen receptor beta (ESR2) polymorphisms in interaction with estrogen receptor alpha (ESR1) and insulin-like growth factor I (IGF1) variants influence the risk of fracture in postmenopausal women

scientific article published in September 2006

Evaluation of commonly used analysis strategies for epigenome- and transcriptome-wide association studies through replication of large-scale population studies

scientific article published on 14 November 2019

Factors for pain in patients with different grades of knee osteoarthritis

scientific article published in May 2013

Finger length pattern as a biomarker for osteoarthritis and chronic joint pain: a population-based study and meta-analysis after systematic review

scientific article published on September 2014

GDF5 single-nucleotide polymorphism rs143383 is associated with lumbar disc degeneration in Northern European women

scientific article

GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures

scientific article published on 03 May 2019

Genetic and environmental influences interact with age and sex in shaping the human methylome.

scientific article published on 7 April 2016

Genetic evidence of assortative mating in humans

scholarly article

Genetic polymorphisms in the locus control region and promoter of GH1 are related to serum IGF-I levels and height in patients with isolated growth hormone deficiency and healthy controls

scientific article published on 15 January 2010

Genetic variation in homocysteine metabolism, cognition, and white matter lesions

scientific article published on 18 November 2008

Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes

scientific article published on 30 October 2017

Genome-wide Association Study for Radiographic Vertebral Fractures: A Potential Role for the 16q24 BMD Locus versus Lessons Learned from Challenging Phenotype Definition

Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis.

scientific article published on 20 March 2018

Genome-wide association analysis identifies six new loci associated with forced vital capacity

scientific article

Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

scientific article published on 24 November 2015

Genome-wide association and functional studies identify a role for IGFBP3 in hip osteoarthritis

scientific article published on 13 June 2014

Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis

scientific journal article

Genome-wide association scan of neuropathic pain symptoms post total joint replacement highlights a variant in the protein-kinase C gene

scientific article published on 4 January 2017

Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging

scientific article

Genome-wide association study for radiographic vertebral fractures: a potential role for the 16q24 BMD locus

scientific article

Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero

scientific article published on 12 April 2018

Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region

scientific article

Genome-wide identification of directed gene networks using large-scale population genomics data

scientific article published in Nature Communications

Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inference

scientific article published on 28 August 2020

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

scientific article

Genome-wide meta-analysis of common variant differences between men and women

scientific article published on 27 July 2012

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

scientific article

Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances

Gremlin 1, Frizzled-related protein, and Dkk-1 are key regulators of human articular cartilage homeostasis

scientific article published on 01 October 2012

Height in pre- and postmenopausal women is influenced by estrogen receptor alpha gene polymorphisms

scientific article published in January 2004

High bone mineral density and fracture risk in type 2 diabetes as skeletal complications of inadequate glucose control: the Rotterdam Study

scientific article published on 11 January 2013

Homocysteine and fracture prevention

scientific article published in March 2005

Homocysteine levels and the risk of osteoporotic fracture

scientific article

Homocysteine levels associate with subtle changes in leukocyte DNA methylation: an epigenome-wide analysis

scientific article published on 9 October 2017

Human age estimation from blood using mRNA, DNA methylation, DNA rearrangement, and telomere length

scientific article published on 24 May 2016

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis

scientific article published on 11 March 2008

Identification of context-dependent expression quantitative trait loci in whole blood

scientific article published on 5 December 2016

Identification of genetic loci associated with Helicobacter pylori serologic status

scientific article published in May 2013

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study ⬇️

scientific article published on July 3, 2012

Interaction between plasma homocysteine and the MTHFR c.677C > T polymorphism is associated with site-specific changes in DNA methylation in humans

scientific article published on 06 August 2018

Interactions between dietary vitamin E intake and SIRT1 genetic variation influence body mass index.

scientific article published on 24 March 2010

Intestinal microbiome composition and its relation to joint pain and inflammation

scientific article published on 25 October 2019

Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand

scientific article published on June 2009

Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis

scientific article published on March 2008

Large-scale analysis of association between polymorphisms in the transforming growth factor beta 1 gene (TGFB1) and osteoporosis: the GENOMOS study

scientific article published on 3 December 2007

Large-scale evidence for the effect of the COLIA1 Sp1 polymorphism on osteoporosis outcomes: the GENOMOS study

scientific article

Loci at chromosomes 13, 19 and 20 influence age at natural menopause

scientific article

Lower sex hormone levels are associated with more chronic musculoskeletal pain in community-dwelling elderly women

scientific article published on July 2016

Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns

scientific article published on 10 February 2016

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance

scientific article published on 23 July 2014

Meta-analysis of epigenome-wide association studies of cognitive abilities

scientific article published on 8 January 2018

Meta-analysis of genome-wide association data identifies two loci influencing age at menarche

scientific article

Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22

scientific article

Methylenetetrahydrofolate reductase C677T genotype and PD.

scientific article published in June 2005

Multi-Omics Analysis Reveals MicroRNAs Associated With Cardiometabolic Traits

scientific article published on 27 February 2020

No clear association between female hormonal aspects and osteoarthritis of the hand, hip and knee: a systematic review

scientific article published on 16 July 2009

Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis

scientific article

Osteoporosis

Peripheral Blood Transcriptomic Signatures of Fasting Glucose and Insulin Concentrations

scientific article

Polymorphisms in the sclerosteosis/van Buchem disease gene (SOST) region are associated with bone-mineral density in elderly whites

scientific article

Population genomics in a disease targeted primary cell model

scientific article published on 04 August 2009

Population-specific genetic variation in large sequencing data sets: why more data is still better

scientific article published on 19 July 2017

Promoter and 3'-untranslated-region haplotypes in the vitamin d receptor gene predispose to osteoporotic fracture: the rotterdam study

scientific article

Publisher Correction: GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures

scientific article published on 24 May 2019

RNA-Seq in 296 phased trios provides a high-resolution map of genomic imprinting.

scientific article

Rapid Low-Cost Microarray-Based Genotyping for Genetic Screening in Primary Immunodeficiency

scientific article published on 15 April 2020

Rationale and design of the B-PROOF study, a randomized controlled trial on the effect of supplemental intake of vitamin B12 and folic acid on fracture incidence

scientific article

Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs

scientific article

Reply to P-A Dugué et al

scientific article published on 01 January 2020

SIRT1 genetic variation and mortality in type 2 diabetes: interaction with smoking and dietary niacin

scientific article published on 10 January 2009

SIRT1 genetic variation is related to BMI and risk of obesity

scientific article published on 09 September 2009

Scheuermann disease: evaluation of radiological criteria and population prevalence

scientific article published in September 2013

Scheuermann's Disease: Evaluation of Radiological Criteria and Population Prevalence

scientific article

Serum C reactive protein levels and genetic variation in the CRP gene are not associated with the prevalence, incidence or progression of osteoarthritis independent of body mass index

scientific article

Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31.

scientific article published on 13 April 2014

Skewed X-inactivation is common in the general female population

scientific article published on 14 December 2018

Smoking-related changes in DNA methylation and gene expression are associated with cardio-metabolic traits

scientific article published on 22 October 2020

Systematic identification of trans eQTLs as putative drivers of known disease associations

scientific article (publication date: October 2013)

Telomere Length and the Risk of Alzheimer's Disease: The Rotterdam Study

scientific article published on 01 January 2020

The -1997 G/T and Sp1 polymorphisms in the collagen type I alpha1 (COLIA1) gene in relation to changes in femoral neck bone mineral density and the risk of fracture in the elderly: the Rotterdam study

scientific article published on 7 June 2007

The DOT1L rs12982744 polymorphism is associated with osteoarthritis of the hip with genome-wide statistical significance in males

scientific article published on 16 March 2013

The GDF5 rs143383 polymorphism is associated with osteoarthritis of the knee with genome-wide statistical significance

scientific article

The RIZ Pro704 insertion-deletion polymorphism, bone mineral density and fracture risk: the Rotterdam study

scientific article published on 23 October 2007

The association between common vitamin D receptor gene variations and osteoporosis: a participant-level meta-analysis

scientific article

The association between lumbar disc degeneration and low back pain: the influence of age, gender, and individual radiographic features

scientific article

The catechol-O-methyltransferase Met158 low-activity allele and association with nonvertebral fracture risk in elderly men

scientific article published on 15 May 2007

The effects of long-term daily folic acid and vitamin B12 supplementation on genome-wide DNA methylation in elderly subjects

scientific article

The interrelatedness of chronic cough and chronic pain

scientific article published on 29 October 2020

The role of vitamin D receptor gene polymorphisms in bone biology

scientific article

The transcriptional landscape of age in human peripheral blood

scientific article

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

scientific article

Tissue effect on genetic control of transcript isoform variation

scientific article

Tobacco smoking is associated with DNA methylation of diabetes susceptibility genes

scientific article published on 29 January 2016

Tobacco smoking is associated with methylation of genes related to coronary artery disease

scientific article

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

scientific article

Translation of clinical problems in osteoarthritis into pathophysiological research goals

scientific article published on 26 May 2016

Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies

scientific article

Twenty loci associated with bone mineral density identified by large-scale meta-analysis of genome-wide association datasets

Uncompromised 10-year survival of oldest old carrying somatic mutations in DNMT3A and TET2.

scientific article published on 29 January 2016

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

scholarly article published 19 October 2018

Validated inference of smoking habits from blood with a finite DNA methylation marker set

scientific article published on 07 September 2019

Variation at the ANP32A gene is associated with risk of hip osteoarthritis in women.

scientific article

Vitamin D binding protein genotype and osteoporosis

scientific article published on 02 June 2009

Vitamin D receptor gene haplotype is associated with body height and bone size

scientific article published on 9 January 2007

Vitamin D receptor gene polymorphisms in relation to Vitamin D related disease states

scientific article published in May 2004

Vitamin D-binding protein polymorphisms are not associated with development of (multiple) basal cell carcinomas

scientific article published on 31 August 2010

Whole Blood DNA Methylation Signatures of Diet Are Associated with Cardiovascular Disease Risk Factors and All-cause Mortality

scientific article published on 11 June 2020

Whole Blood Gene Expression Associated with Clinical Biological Age

article

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture

scientific article

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