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List of works by Sven Nylander

Accurate measurement of endogenous adenosine in human blood

scientific article published in PLoS ONE

Adenosine-mediated effects of ticagrelor: evidence and potential clinical relevance

scientific article published on 23 April 2014

Anti-platelet therapy: cyclo-oxygenase inhibition and the use of aspirin with particular regard to dual anti-platelet therapy

scientific article

Boosting the coagulation restores haemostasis in ticagrelor-treated mice

scientific article published on 11 January 2016

Characterisation of species differences in the platelet ADP and thrombin response

scientific article published in January 2006

Characterization of the adenosine pharmacology of ticagrelor reveals therapeutically relevant inhibition of equilibrative nucleoside transporter 1.

scientific article published on 10 January 2014

Chronic treatment with ticagrelor limits myocardial infarct size: an adenosine and cyclooxygenase-2-dependent effect

scientific article published on 10 July 2014

Crushed Versus Integral Tablets of Ticagrelor in ST-Segment Elevation Myocardial Infarction Patients: A Randomized Pharmacokinetic/Pharmacodynamic Study.

scientific article published on 28 August 2015

Dapagliflozin and Ticagrelor Have Additive Effects on the Attenuation of the Activation of the NLRP3 Inflammasome and the Progression of Diabetic Cardiomyopathy: an AMPK-mTOR Interplay

scientific article published on 25 April 2020

Discovery of 9-(1-phenoxyethyl)-2-morpholino-4-oxo-pyrido[1,2-a]pyrimidine-7-carboxamides as oral PI3Kβ inhibitors, useful as antiplatelet agents

scientific article

Discovery of phosphoinositide 3-kinases (PI3K) p110β isoform inhibitor 4-[2-hydroxyethyl(1-naphthylmethyl)amino]-6-[(2S)-2-methylmorpholin-4-yl]-1H-pyrimidin-2-one, an effective antithrombotic agent without associated bleeding and insulin resistance ⬇️

scientific article published on 06 September 2012

Effect of esomeprazole with/without acetylsalicylic acid, omeprazole and lansoprazole on pharmacokinetics and pharmacodynamics of clopidogrel in healthy volunteers

scientific article published on 01 June 2014

Effects of P2Y12 receptor antagonists beyond platelet inhibition--comparison of ticagrelor with thienopyridines

scientific article

Gradual increase in thrombogenicity of juvenile platelets formed upon offset of prasugrel medication.

scientific article published on 25 June 2015

High-dose aspirin in dogs increases vascular resistance with limited additional anti-platelet effect when combined with potent P2Y12 inhibition

scientific article published on 15 February 2013

In vitro anti-platelet potency of ticagrelor in blood samples from infants and children

scientific article

Inverse agonism at the P2Y12 receptor and ENT1 transporter blockade contribute to platelet inhibition by ticagrelor

scientific article published on 30 September 2016

Mode of action of P2Y(12 ) antagonists as inhibitors of platelet function

scientific article published on 12 October 2010

Quantification of unbound concentration of ticagrelor in plasma as a proof of mechanism biomarker of the reversal agent, MEDI2452

scientific article published in PLoS ONE

Reply: To PMID 23312702

scientific article published on 07 June 2013

Structural and functional characterization of a specific antidote for ticagrelor

scientific article published on 18 March 2015

Studies of the interaction of ticagrelor with the P2Y13 receptor and with P2Y13-dependent pro-platelet formation by human megakaryocytes

scientific article published on 08 September 2016

Synergistic action between inhibition of P2Y12/P2Y1 and P2Y12/thrombin in ADP- and thrombin-induced human platelet activation

scientific article published on 20 July 2004

The relative importance of the ADP receptors, P2Y12 and P2Y1, in thrombin-induced platelet activation.

scientific article

Thrombin-induced platelet activation and its inhibition by anticoagulants with different modes of action

scientific article published in February 2003

Ticagrelor Enhances Adenosine-Induced Coronary Vasodilatory Responses in Humans ⬇️

scientific article published on 09 January 2013

Ticagrelor Improves Remodeling, Reduces Apoptosis, Inflammation and Fibrosis and Increases the Number of Progenitor Stem Cells After Myocardial Infarction in a Rat Model of Ischemia Reperfusion

scientific article published on 01 January 2019

Ticagrelor and Rosuvastatin Have Additive Cardioprotective Effects via Adenosine

scientific article published on 10 November 2016

Ticagrelor effectively and reversibly blocks murine platelet P2Y12-mediated thrombosis and demonstrates a requirement for sustained P2Y12 inhibition to prevent subsequent neointima.

scientific article

Ticagrelor protects the heart against reperfusion injury and improves remodeling after myocardial infarction

scientific article published on 4 June 2015

Unraveling the Interaction of Aspirin, Ticagrelor, and Rosuvastatin on the Progression of Atherosclerosis and Inflammation in Diabetic Mice.

scientific article published on 28 November 2017

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