List of works - Laste Stojanovski

A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors

scientific article published on 12 September 2018

Automated design of ligands to polypharmacological profiles.

scientific article

Chemical Validation of Methionyl-tRNA Synthetase as a Druggable Target in Leishmania donovani

scientific article published on 2 October 2017

Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis

scientific article published on 25 May 2016

Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis

scientific article published in Nature

Design and Synthesis of Brain Penetrant Trypanocidal N-Myristoyltransferase Inhibitors.

scientific article published on 10 November 2017

Development of Small-Molecule Trypanosoma brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode.

scientific article published on 23 September 2015

Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi

scientific article

Discovery and Optimization of a Compound Series Active against Trypanosoma cruzi, the Causative Agent of Chagas Disease

scientific article published on 05 March 2020

Discovery of Indoline-2-carboxamide Derivatives as a New Class of Brain-Penetrant Inhibitors of Trypanosoma brucei

scientific article published on 29 September 2015

Discovery of Inhibitors of Trypanosoma brucei by Phenotypic Screening of a Focused Protein Kinase Library

scientific article published on 18 September 2015

Discovery of a Novel Class of Orally Active Trypanocidal N -Myristoyltransferase Inhibitors

scientific article

Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy

scientific article published on 10 September 2016

Essential but not vulnerable: indazole sulfonamides targeting inosine monophosphate dehydrogenase as potential leads against Mycobacterium tuberculosis

scientific article

Identification and optimisation of a series of 8-hydroxy naphthyridines with potent in vitro antileishmanial activity: Initial SAR and assessment of in vivo activity

scientific article published on 14 July 2020

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis

scientific article published on 20 December 2018

Identification of a κ-opioid agonist as a potent and selective lead for drug development against human African trypanosomiasis

scientific article

Lead optimization of a pyrazole sulfonamide series of Trypanosoma brucei N-myristoyltransferase inhibitors: identification and evaluation of CNS penetrant compounds as potential treatments for stage 2 human African trypanosomiasis

scientific article

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

scientific article published on 20 March 2019

N-myristoyltransferase inhibitors as new leads to treat sleeping sickness

scientific article

PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development

scientific article published on 5 March 2013

Pharmacological Validation of N-Myristoyltransferase as a Drug Target in Leishmania donovani

scholarly article by Victoriano Corpas-Lopez et al published 12 November 2018 in ACS Infectious Diseases

Pharmacological validation of N-myristoyltransferase as a drug target in Leishmania donovani

scholarly article by Victoriano Corpas-Lopez et al published 1 November 2018 in ACS Infectious Diseases

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

scientific article published on 08 April 2019

The Anthelmintic Drug Niclosamide and its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1.

scientific article published on 10 December 2017

The R enantiomer of the antitubercular drug PA-824 as a potential oral treatment for visceral Leishmaniasis

scientific article

The anti-trypanosome drug fexinidazole shows potential for treating visceral leishmaniasis

scientific article

The anti-tubercular drug delamanid as a potential oral treatment for visceral leishmaniasis

scientific article published on 24 May 2016

Trisubstituted Pyrimidines as Efficacious and Fast-Acting Antimalarials

scientific article published on 17 June 2016

List of works by Laste Stojanovski

A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors

Automated design of ligands to polypharmacological profiles.

Chemical Validation of Methionyl-tRNA Synthetase as a Druggable Target in Leishmania donovani

Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis

Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis

Design and Synthesis of Brain Penetrant Trypanocidal N-Myristoyltransferase Inhibitors.

Development of Small-Molecule Trypanosoma brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode.

Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi

Discovery and Optimization of a Compound Series Active against Trypanosoma cruzi, the Causative Agent of Chagas Disease

Discovery of Indoline-2-carboxamide Derivatives as a New Class of Brain-Penetrant Inhibitors of Trypanosoma brucei

Discovery of Inhibitors of Trypanosoma brucei by Phenotypic Screening of a Focused Protein Kinase Library

Discovery of a Novel Class of Orally Active Trypanocidal N -Myristoyltransferase Inhibitors

Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy

Essential but not vulnerable: indazole sulfonamides targeting inosine monophosphate dehydrogenase as potential leads against Mycobacterium tuberculosis

Identification and optimisation of a series of 8-hydroxy naphthyridines with potent in vitro antileishmanial activity: Initial SAR and assessment of in vivo activity

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis

Identification of a κ-opioid agonist as a potent and selective lead for drug development against human African trypanosomiasis

Lead optimization of a pyrazole sulfonamide series of Trypanosoma brucei N-myristoyltransferase inhibitors: identification and evaluation of CNS penetrant compounds as potential treatments for stage 2 human African trypanosomiasis

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

N-myristoyltransferase inhibitors as new leads to treat sleeping sickness

PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development

Pharmacological Validation of N-Myristoyltransferase as a Drug Target in Leishmania donovani

Pharmacological validation of N-myristoyltransferase as a drug target in Leishmania donovani

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

The Anthelmintic Drug Niclosamide and its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1.

The R enantiomer of the antitubercular drug PA-824 as a potential oral treatment for visceral Leishmaniasis

The anti-trypanosome drug fexinidazole shows potential for treating visceral leishmaniasis

The anti-tubercular drug delamanid as a potential oral treatment for visceral leishmaniasis

Trisubstituted Pyrimidines as Efficacious and Fast-Acting Antimalarials