List of works - Wakako Umene-Nakano

A case of late-onset Tourette's disorder successfully treated with aripiprazole: view from blood levels of catecholamine metabolites and brain-derived neurotrophic factor (BDNF).

scientific article published in January 2009

A case of schizophrenia with Meige syndrome induced by long-term aripiprazole successfully treated with perospirone ⬇️

scientific article published on September 16, 2010

A case with occurring adverse effects when cross-over titration from fluvoxamine to paroxetine associated with increasing the plasma fluvoxamine level in major depressive disorder

scientific article published in January 2009

A close correlation between plasma and serum levels of brain-derived neurotrophic factor (BDNF) in healthy volunteers

scientific article

Abnormal white matter integrity in the corpus callosum among smokers: tract-based spatial statistics

scientific article

Acute risperidone treatment did not increase daily cigarette consumption or plasma levels of cotinine and caffeine: a pilot study

scientific article

Adding a low dose atypical antipsychotic drug to an antidepressant induced a rapid increase of plasma brain-derived neurotrophic factor levels in patients with treatment-resistant depression

scientific article published on 11 December 2009

Addition of risperidone to sertraline improves sertraline-resistant refractory depression without influencing plasma concentrations of sertraline and desmethylsertraline

scientific article

An evaluation of polymorphisms in casein kinase 1 delta and epsilon genes in major psychiatric disorders

scientific article published on 7 September 2012

Aripiprazole altered plasma levels of brain-derived neurotrophic factor and catecholamine metabolites in first-episode untreated Japanese schizophrenia patients

scientific article

Aripiprazole improves various cognitive and behavioral impairments after traumatic brain injury: a case report ⬇️

scientific article published on June 14, 2012

Association analysis of SIGMAR1 with major depressive disorder and SSRI response

scientific article published on 21 February 2010

Association between plasma nitric oxide metabolites levels and negative symptoms of schizophrenia: a pilot study

scientific article published in March 2010

Associations between plasma levels of 3-methoxy-4-hydroxyphenylglycol (MHPG) and negative symptoms or cognitive impairments in early-stage schizophrenia

scientific article published in December 2009

Attitudes of early-career psychiatrists in Japan toward child and adolescent psychiatry and their career decision.

scientific article published on February 2010

Blood levels of brain-derived neurotrophic factor (BDNF) in major depressive disorder

scientific article published on January 2010

Brain-derived neurotrophic factor (BDNF) and mood disorder

scientific article published on November 2010

COMT Val158Met, but not BDNF Val66Met, is associated with white matter abnormalities of the temporal lobe in patients with first-episode, treatment-naïve major depressive disorder: a diffusion tensor imaging study

scientific article

Comparison of lithium, aripiprazole and olanzapine as augmentation to paroxetine for inpatients with major depressive disorder

scientific article

Comparison of the efficacy between paroxetine and sertraline augmented with aripiprazole in patients with refractory major depressive disorder

scientific article published on 17 July 2012

Continuous decrease in serum brain-derived neurotrophic factor (BDNF) levels in a neuropsychiatric syndrome of systemic lupus erythematosus patient with organic brain changes

scientific article published on December 2008

Critical examination of a correlation between brain gamma-aminobutyric acid (GABA) concentrations and a personality trait of extroversion in healthy volunteers as measured by a 3 Tesla proton magnetic resonance spectroscopy study

scientific article published on 12 March 2010

Current smoking rate in patients with psychiatric disorders in Japan: questionnaire survey

scientific article published on 17 April 2013

Differences in the preferred antipsychotics for acute schizophrenia among young psychiatrists in two regions of Japan

scientific article published on 31 May 2010

Different patterns of longitudinal changes in plasma levels of catecholamine metabolites and brain-derived neurotrophic factor after administration of atypical antipsychotics in first episode untreated schizophrenic patients

scientific article published in March 2010

Duloxetine, a Selective Noradrenaline Reuptake Inhibitor, Increased Plasma Levels of 3-Methoxy-4-hydroxyphenylglycol but Not Homovanillic Acid in Patients with Major Depressive Disorder

scientific article published on 24 April 2014

Effects of antidepressants on plasma metabolites of nitric oxide in major depressive disorder: comparison between milnacipran and paroxetine

scientific article published on 5 August 2009

Efficacy of electroconvulsive therapy is associated with changing blood levels of homovanillic acid and brain-derived neurotrophic factor (BDNF) in refractory depressed patients: a pilot study

scientific article

Fluctuating plasma levels of the active moiety of risperidone is related to occurrence of extrapyramidal symptoms

scientific article published on 01 January 2009

Follow-up Study on Electroconvulsive Therapy in Treatment-resistant Depressed Patients after Remission: A Chart Review

scientific article published on 24 April 2013

Frequency of pervasive developmental disorders and supports for workers with pervasive developmental disorders in workplaces: a field survey of psychiatrists well acquainted with occupational practices

scientific article published on 28 November 2011

Further evidence of an association between a genetic variant in BMP7 and treatment response to SSRIs in major depressive disorder

scientific article

GTP cyclohydrolase 1 gene haplotypes as predictors of SSRI response in Japanese patients with major depressive disorder

scientific article published on 6 July 2012

Grapefruit juice alters plasma sertraline levels after single ingestion of sertraline in healthy volunteers

scientific article published in January 2009

Higher plasma interleukin-6 (IL-6) level is associated with SSRI- or SNRI-refractory depression

scientific article published on 28 March 2009

Issues and the current situation of the new compulsory residency training program in Japan: the results of an attitude survey for young career psychiatrists

scientific article published in January 2010

Lack of association between MAGEL2 and schizophrenia and mood disorders in the Japanese population

scientific article published on 14 May 2010

Nationwide survey of work environment, work-life balance and burnout among psychiatrists in Japan

scientific article

No Association between the Response to the Addition of an Atypical Antipsychotic Drug to an SSRI or SNRI and the BDNF (Val66Met) Polymorphism in Refractory Major Depressive Disorder in Japanese Patients

scientific article published on 30 April 2012

No association between BDNF Val66Met polymorphism and emergence of psychiatric symptoms in systemic lupus erythematosus patients ⬇️

scientific article published on June 16, 2011

No difference in adherence to paroxetine between depressed patients with early remission and those with late remission based on monitoring of plasma paroxetine concentrations ⬇️

scientific article published on August 1, 2010

No significant association between brain-derived neurotrophic factor gene rs6265 and cognitive function in Japanese patients with schizophrenia.

scientific article

No support for replication of the genetic variants identified by a recent mega-analysis of the treatment response to antidepressants.

scientific article

Nonadherence to paroxetine: a study based on monitoring plasma paroxetine levels

scientific article published in February 2010

Pharmacogenetic study of serotonin 6 receptor gene with antidepressant response in major depressive disorder in the Japanese population

scientific article published on August 2010

Plasma Levels of Metabolites of Catecholamine in Nicotine-Dependent Patients Treated With Varenicline ⬇️

scientific article published on October 17, 2011

Plasma catecholamine metabolite levels and the activities of psychiatric symptoms in systemic lupus erythematosus

scientific article published in March 2013

Plasma levels of brain‐derived neurotrophic factor and interleukin‐6 in patients with dysthymic disorder: comparison with age‐ and sex‐matched major depressed patients and healthy controls ⬇️

scientific article published on November 1, 2010

Plasma levels of interleukin-6 and selective serotonin reuptake inhibitor response in patients with major depressive disorder

scientific article published on 30 June 2013

Possible association between ubiquitin-specific peptidase 46 gene and major depressive disorders in the Japanese population

scientific article published on 12 June 2011

Predictive factors for responding to sertraline treatment: views from plasma catecholamine metabolites and serotonin transporter polymorphism

scientific article published on 13 October 2009

Rapid response to paroxetine is associated with plasma paroxetine levels at 4 but not 8 weeks of treatment, and is independent of serotonin transporter promoter polymorphism in Japanese depressed patients.

scientific article published in August 2009

Reduction of brain gamma-aminobutyric acid (GABA) concentrations in early-stage schizophrenia patients: 3T Proton MRS study.

scientific article

Relationship between a BDNF gene polymorphism and the brain volume in treatment-naive patients with major depressive disorder: A VBM analysis of brain MRI.

scientific article published on 30 May 2015

Relationship between the catechol-O-methyl transferase Val108/158Met genotype and brain volume in treatment-naive major depressive disorder: Voxel-based morphometry analysis

scientific article published on 31 July 2015

Relationship between white matter integrity and serum cortisol levels in drug-naive patients with major depressive disorder: diffusion tensor imaging study using tract-based spatial statistics

scientific article published on 18 February 2016

Relationships between stress, social adaptation, personality traits, brain-derived neurotrophic factor and 3-methoxy-4-hydroxyphenylglycol plasma concentrations in employees at a publishing company in Japan ⬇️

scientific article published on September 15, 2010

Reliability, validity and clinical utility of a Japanese version of the Social Adaptation Self‐evaluation Scale as calibrated using the Beck Depression Inventory ⬇️

scientific article published on December 1, 2011

SIRT1 gene is associated with major depressive disorder in the Japanese population

scientific article published on 7 May 2010

Serotonin 6 receptor gene and mood disorders: case-control study and meta-analysis

scientific article published on 13 April 2010

Serum Brain–Derived Neurotrophic Factor Levels at 6 Months After Remission Are Not Associated With Subsequent Depressive Episodes ⬇️

scientific article published on February 1, 2013

Serum Levels of Brain-Derived Neurotrophic Factor at 4 Weeks and Response to Treatment with SSRIs.

scientific article published on 21 January 2014

Serum brain-derived neurotrophic factor levels as a novel biological marker for the activities of psychiatric symptoms in systemic lupus erythematosus

scientific article published in March 2010

Serum levels of brain-derived neurotrophic factor (BDNF), BDNF gene Val66Met polymorphism, or plasma catecholamine metabolites, and response to mirtazapine in Japanese patients with major depressive disorder (MDD) ⬇️

scientific article published on August 10, 2012

Serum levels of brain-derived neurotrophic factor in comorbidity of depression and alcohol dependence.

scientific article published in July 2009

Several prescription patterns of antipsychotic drugs influence cognitive functions in Japanese chronic schizophrenia patients ⬇️

scientific article published on 05 December 2011

Six-month treatment with atypical antipsychotic drugs decreased frontal-lobe levels of glutamate plus glutamine in early-stage first-episode schizophrenia ⬇️

scientific article published on April 3, 2012

Steroid psychosis in a polyarteritis nodosa patient successfully treated with risperidone: tracking serum brain-derived neurotrophic factor levels longitudinally ⬇️

scientific article published on January 23, 2012

The CLOCK gene and mood disorders: a case-control study and meta-analysis

scientific article published in November 2011

The Case of a Depressed Man Who Exhibited Hyperprolactinemia and Galactopoiesis After Electroconvulsive Therapy ⬇️

scientific article published on March 1, 2012

The brain-derived neurotrophic factor (BDNF) polymorphism Val66Met is associated with neither serum BDNF level nor response to selective serotonin reuptake inhibitors in depressed Japanese patients

scientific article published on 19 February 2011

The cognitive profile of aripiprazole differs from that of other atypical antipsychotics in schizophrenia patients ⬇️

scientific article published on March 29, 2012

The serotonin 1A receptor gene confer susceptibility to mood disorders: results from an extended meta-analysis of patients with major depression and bipolar disorder

scientific article published on 03 July 2012

Three polymorphisms of the eNOS gene and plasma levels of metabolites of nitric oxide in depressed Japanese patients: a preliminary report

scientific article published in October 2011

Varenicline does not increase serum BDNF levels in patients with nicotine dependence

scientific article published in April 2010

Views on the new psychiatric specialist certification system from the perspective of those experiencing the postgraduate psychiatric training system in Japan

scientific article published on 01 January 2011

[A thought on postgraduate psychiatric education from the viewpoint of residents in the latter stage of training based on the system of training of psychiatric specialists--the latter part of the psychiatric training at university hospitals]

scientific article published on 01 January 2009

[Postgraduate psychiatric training in Japan]

scientific article published on 01 January 2009

List of works by Wakako Umene-Nakano

A case of late-onset Tourette's disorder successfully treated with aripiprazole: view from blood levels of catecholamine metabolites and brain-derived neurotrophic factor (BDNF).

A case of schizophrenia with Meige syndrome induced by long-term aripiprazole successfully treated with perospirone ⬇️

A case with occurring adverse effects when cross-over titration from fluvoxamine to paroxetine associated with increasing the plasma fluvoxamine level in major depressive disorder

A close correlation between plasma and serum levels of brain-derived neurotrophic factor (BDNF) in healthy volunteers

Abnormal white matter integrity in the corpus callosum among smokers: tract-based spatial statistics

Acute risperidone treatment did not increase daily cigarette consumption or plasma levels of cotinine and caffeine: a pilot study

Adding a low dose atypical antipsychotic drug to an antidepressant induced a rapid increase of plasma brain-derived neurotrophic factor levels in patients with treatment-resistant depression

Addition of risperidone to sertraline improves sertraline-resistant refractory depression without influencing plasma concentrations of sertraline and desmethylsertraline

An evaluation of polymorphisms in casein kinase 1 delta and epsilon genes in major psychiatric disorders

Aripiprazole altered plasma levels of brain-derived neurotrophic factor and catecholamine metabolites in first-episode untreated Japanese schizophrenia patients

Aripiprazole improves various cognitive and behavioral impairments after traumatic brain injury: a case report ⬇️

Association analysis of SIGMAR1 with major depressive disorder and SSRI response

Association between plasma nitric oxide metabolites levels and negative symptoms of schizophrenia: a pilot study

Associations between plasma levels of 3-methoxy-4-hydroxyphenylglycol (MHPG) and negative symptoms or cognitive impairments in early-stage schizophrenia

Attitudes of early-career psychiatrists in Japan toward child and adolescent psychiatry and their career decision.

Blood levels of brain-derived neurotrophic factor (BDNF) in major depressive disorder

Brain-derived neurotrophic factor (BDNF) and mood disorder

COMT Val158Met, but not BDNF Val66Met, is associated with white matter abnormalities of the temporal lobe in patients with first-episode, treatment-naïve major depressive disorder: a diffusion tensor imaging study

Comparison of lithium, aripiprazole and olanzapine as augmentation to paroxetine for inpatients with major depressive disorder

Comparison of the efficacy between paroxetine and sertraline augmented with aripiprazole in patients with refractory major depressive disorder

Continuous decrease in serum brain-derived neurotrophic factor (BDNF) levels in a neuropsychiatric syndrome of systemic lupus erythematosus patient with organic brain changes

Critical examination of a correlation between brain gamma-aminobutyric acid (GABA) concentrations and a personality trait of extroversion in healthy volunteers as measured by a 3 Tesla proton magnetic resonance spectroscopy study

Current smoking rate in patients with psychiatric disorders in Japan: questionnaire survey

Differences in the preferred antipsychotics for acute schizophrenia among young psychiatrists in two regions of Japan

Different patterns of longitudinal changes in plasma levels of catecholamine metabolites and brain-derived neurotrophic factor after administration of atypical antipsychotics in first episode untreated schizophrenic patients

Duloxetine, a Selective Noradrenaline Reuptake Inhibitor, Increased Plasma Levels of 3-Methoxy-4-hydroxyphenylglycol but Not Homovanillic Acid in Patients with Major Depressive Disorder

Effects of antidepressants on plasma metabolites of nitric oxide in major depressive disorder: comparison between milnacipran and paroxetine

Efficacy of electroconvulsive therapy is associated with changing blood levels of homovanillic acid and brain-derived neurotrophic factor (BDNF) in refractory depressed patients: a pilot study

Fluctuating plasma levels of the active moiety of risperidone is related to occurrence of extrapyramidal symptoms

Follow-up Study on Electroconvulsive Therapy in Treatment-resistant Depressed Patients after Remission: A Chart Review

Frequency of pervasive developmental disorders and supports for workers with pervasive developmental disorders in workplaces: a field survey of psychiatrists well acquainted with occupational practices

Further evidence of an association between a genetic variant in BMP7 and treatment response to SSRIs in major depressive disorder

GTP cyclohydrolase 1 gene haplotypes as predictors of SSRI response in Japanese patients with major depressive disorder

Grapefruit juice alters plasma sertraline levels after single ingestion of sertraline in healthy volunteers

Higher plasma interleukin-6 (IL-6) level is associated with SSRI- or SNRI-refractory depression

Issues and the current situation of the new compulsory residency training program in Japan: the results of an attitude survey for young career psychiatrists

Lack of association between MAGEL2 and schizophrenia and mood disorders in the Japanese population

Nationwide survey of work environment, work-life balance and burnout among psychiatrists in Japan

No Association between the Response to the Addition of an Atypical Antipsychotic Drug to an SSRI or SNRI and the BDNF (Val66Met) Polymorphism in Refractory Major Depressive Disorder in Japanese Patients

No association between BDNF Val66Met polymorphism and emergence of psychiatric symptoms in systemic lupus erythematosus patients ⬇️

No difference in adherence to paroxetine between depressed patients with early remission and those with late remission based on monitoring of plasma paroxetine concentrations ⬇️

No significant association between brain-derived neurotrophic factor gene rs6265 and cognitive function in Japanese patients with schizophrenia.

No support for replication of the genetic variants identified by a recent mega-analysis of the treatment response to antidepressants.

Nonadherence to paroxetine: a study based on monitoring plasma paroxetine levels

Pharmacogenetic study of serotonin 6 receptor gene with antidepressant response in major depressive disorder in the Japanese population

Plasma Levels of Metabolites of Catecholamine in Nicotine-Dependent Patients Treated With Varenicline ⬇️

Plasma catecholamine metabolite levels and the activities of psychiatric symptoms in systemic lupus erythematosus

Plasma levels of brain‐derived neurotrophic factor and interleukin‐6 in patients with dysthymic disorder: comparison with age‐ and sex‐matched major depressed patients and healthy controls ⬇️

Plasma levels of interleukin-6 and selective serotonin reuptake inhibitor response in patients with major depressive disorder

Possible association between ubiquitin-specific peptidase 46 gene and major depressive disorders in the Japanese population

Predictive factors for responding to sertraline treatment: views from plasma catecholamine metabolites and serotonin transporter polymorphism

Rapid response to paroxetine is associated with plasma paroxetine levels at 4 but not 8 weeks of treatment, and is independent of serotonin transporter promoter polymorphism in Japanese depressed patients.

Reduction of brain gamma-aminobutyric acid (GABA) concentrations in early-stage schizophrenia patients: 3T Proton MRS study.

Relationship between a BDNF gene polymorphism and the brain volume in treatment-naive patients with major depressive disorder: A VBM analysis of brain MRI.

Relationship between the catechol-O-methyl transferase Val108/158Met genotype and brain volume in treatment-naive major depressive disorder: Voxel-based morphometry analysis

Relationship between white matter integrity and serum cortisol levels in drug-naive patients with major depressive disorder: diffusion tensor imaging study using tract-based spatial statistics

Relationships between stress, social adaptation, personality traits, brain-derived neurotrophic factor and 3-methoxy-4-hydroxyphenylglycol plasma concentrations in employees at a publishing company in Japan ⬇️

Reliability, validity and clinical utility of a Japanese version of the Social Adaptation Self‐evaluation Scale as calibrated using the Beck Depression Inventory ⬇️

SIRT1 gene is associated with major depressive disorder in the Japanese population

Serotonin 6 receptor gene and mood disorders: case-control study and meta-analysis

Serum Brain–Derived Neurotrophic Factor Levels at 6 Months After Remission Are Not Associated With Subsequent Depressive Episodes ⬇️

Serum Levels of Brain-Derived Neurotrophic Factor at 4 Weeks and Response to Treatment with SSRIs.

Serum brain-derived neurotrophic factor levels as a novel biological marker for the activities of psychiatric symptoms in systemic lupus erythematosus

Serum levels of brain-derived neurotrophic factor (BDNF), BDNF gene Val66Met polymorphism, or plasma catecholamine metabolites, and response to mirtazapine in Japanese patients with major depressive disorder (MDD) ⬇️

Serum levels of brain-derived neurotrophic factor in comorbidity of depression and alcohol dependence.

Several prescription patterns of antipsychotic drugs influence cognitive functions in Japanese chronic schizophrenia patients ⬇️

Six-month treatment with atypical antipsychotic drugs decreased frontal-lobe levels of glutamate plus glutamine in early-stage first-episode schizophrenia ⬇️

Steroid psychosis in a polyarteritis nodosa patient successfully treated with risperidone: tracking serum brain-derived neurotrophic factor levels longitudinally ⬇️

The CLOCK gene and mood disorders: a case-control study and meta-analysis

The Case of a Depressed Man Who Exhibited Hyperprolactinemia and Galactopoiesis After Electroconvulsive Therapy ⬇️

The brain-derived neurotrophic factor (BDNF) polymorphism Val66Met is associated with neither serum BDNF level nor response to selective serotonin reuptake inhibitors in depressed Japanese patients

The cognitive profile of aripiprazole differs from that of other atypical antipsychotics in schizophrenia patients ⬇️

The serotonin 1A receptor gene confer susceptibility to mood disorders: results from an extended meta-analysis of patients with major depression and bipolar disorder

Three polymorphisms of the eNOS gene and plasma levels of metabolites of nitric oxide in depressed Japanese patients: a preliminary report

Varenicline does not increase serum BDNF levels in patients with nicotine dependence

Views on the new psychiatric specialist certification system from the perspective of those experiencing the postgraduate psychiatric training system in Japan

[A thought on postgraduate psychiatric education from the viewpoint of residents in the latter stage of training based on the system of training of psychiatric specialists--the latter part of the psychiatric training at university hospitals]

[Postgraduate psychiatric training in Japan]