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List of works by Manuela Nieto-Rostro

A CaV2.1 N-terminal fragment relieves the dominant-negative inhibition by an Episodic ataxia 2 mutant

scientific article published on 31 May 2016

Ablation of αδ-1 inhibits cell-surface trafficking of endogenous N-type calcium channels in the pain pathway in vivo

article published in the Proceedings of the National Academy of Sciences of the United States of America

Effect of knockout of α2δ-1 on action potentials in mouse sensory neurons

scientific article published on August 2016

Fragile X mental retardation protein controls synaptic vesicle exocytosis by modulating N-type calcium channel density

scientific journal article

Interaction via a key tryptophan in the I-II linker of N-type calcium channels is required for beta1 but not for palmitoylated beta2, implicating an additional binding site in the regulation of channel voltage-dependent properties

scientific journal article

LRP1 influences trafficking of N-type calcium channels via interaction with the auxiliary α2δ-1 subunit

scientific article published on 3 March 2017

Labelling of the 3D structure of the cardiac L-type voltage-gated calcium channel

scientific article published on 01 November 2009

N terminus is key to the dominant negative suppression of Ca(V)2 calcium channels: implications for episodic ataxia type 2.

scientific article published on 10 November 2009

Pharmacological disruption of calcium channel trafficking by the alpha2delta ligand gabapentin

scientific article

Proteolytic maturation of α2δ represents a checkpoint for activation and neuronal trafficking of latent calcium channels ⬇️

scientific article published on 26 October 2016

The alpha2delta subunits of voltage-gated calcium channels form GPI-anchored proteins, a posttranslational modification essential for function

scientific article

The ducky(2J) mutation in Cacna2d2 results in reduced spontaneous Purkinje cell activity and altered gene expression

scientific article

The increased trafficking of the calcium channel subunit alpha2delta-1 to presynaptic terminals in neuropathic pain is inhibited by the alpha2delta ligand pregabalin

scientific article

Thrombospondin-4 reduces binding affinity of [(3)H]-gabapentin to calcium-channel α2δ-1-subunit but does not interact with α2δ-1 on the cell-surface when co-expressed

scientific article published on 14 April 2016

α2δ-1 gene deletion affects somatosensory neuron function and delays mechanical hypersensitivity in response to peripheral nerve damage

scientific article published on October 2013

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